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The map label for this gene is trpD

Identifier: 13470814

GI number: 13470814

Start: 479468

End: 480478

Strand: Direct

Name: trpD

Synonym: mlr0614

Alternate gene names: 13470814

Gene position: 479468-480478 (Clockwise)

Preceding gene: 13470813

Following gene: 13470815

Centisome position: 6.81

GC content: 66.67

Gene sequence:

>1011_bases
ATGAGCGCGTTGAAAACCCATATCGCCAAGGTGGCGGCCGGCACCGCGCTTTCCTTCGAGGAAGCGCGCGAGGCCTTCGA
CATAATCATGTCGGGCGACGCGACCCCTGGGCAGATCGGTGGTTTCCTGATGGCGCTTCGCGTACGCGGTGAGACAGTGA
GCGAGATTTCGGGCGCTGTCGCCACGATGCGGGCCAAGATGCTGCGCGTTGAGGCGCCCGCGGGTGCCATCGATATCGTC
GGCACGGGCGGCGACAATTCCCACAGCGTCAACATTTCGACGGGCTCGGCCTTCGTCATCGCCGCCGCCGGCGTGCCGGT
CGCCAAGCACGGCAATCGCGGCCTGTCGTCGCTGACCGGCGCGGCCGATGTCCTGATCGCGCTTGGGGTCAAGATAGACA
TTCCGCCGGACGCGATCGGCCGTTGCATCCACGAAGCCGGCGTCGGCTTCATGTTCGCGCCGGCGCACCATCCGGCTATG
AAGCATGTCGGCCCGACTCGCGTCGAGCTCGGCACCCGGACCATCTTCAACCTGCTCGGGCCCCTCTCCAATCCGGCTGG
CGTCGTCAGGCAGATGGTCGGTGTGTTCCTGCCGGAATGGATCTTGCCCGTGGCCGAGACATTGAAGGCGCTGGGCACCG
AGCATGCCTGGGTCGTCCATGGCGACGGCTATGACGAAATCACCACCACCGGCGAGACCCAGGTGGCGGAACTGATCGGC
GGTGAGATCCGCAGCTTCACGCTGACCCCGGAAGAGGTCGGACTGAAGCGCCACACCAAGGACGAGCTGCGCGGCGGCGA
CGCCGCCTACAACGCCAACGCCTTGCGCGACATGCTGGACGGCGCTGCCGGCGCCTATCGCGACACCGTGCTGATGAATG
CCGGCGCCGGGCTGGTGATCGCGGGCAAGGCGACGACGCTCGGCGACGGCATCGCGCTCGCAGCGCAAGCCATAGACAGC
GGCCGGGCGTTGCAGGTGCTCGACCGGCTGGTCGAAATTTCGAACGGGTGA

Upstream 100 bases:

>100_bases
CCGGCATGTCGGACGATCTGCTCGACCAATTGGTGGCGCAGTTGCAGACGCAGTACGACGTCCGCATCGACCAGGCCGCC
GTTGCCCAAGCCGCGACAAG

Downstream 100 bases:

>100_bases
ACCGTGTCTGACATTCTGCGCAAGATCGAGGCCTACAAGCGCGACGAGATCGCCGCCGCCAAGGCACACGTGCCGCTGGC
CGAGATCAAGGCGCGGGCGA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSALKTHIAKVAAGTALSFEEAREAFDIIMSGDATPGQIGGFLMALRVRGETVSEISGAVATMRAKMLRVEAPAGAIDIV
GTGGDNSHSVNISTGSAFVIAAAGVPVAKHGNRGLSSLTGAADVLIALGVKIDIPPDAIGRCIHEAGVGFMFAPAHHPAM
KHVGPTRVELGTRTIFNLLGPLSNPAGVVRQMVGVFLPEWILPVAETLKALGTEHAWVVHGDGYDEITTTGETQVAELIG
GEIRSFTLTPEEVGLKRHTKDELRGGDAAYNANALRDMLDGAAGAYRDTVLMNAGAGLVIAGKATTLGDGIALAAQAIDS
GRALQVLDRLVEISNG

Sequences:

>Translated_336_residues
MSALKTHIAKVAAGTALSFEEAREAFDIIMSGDATPGQIGGFLMALRVRGETVSEISGAVATMRAKMLRVEAPAGAIDIV
GTGGDNSHSVNISTGSAFVIAAAGVPVAKHGNRGLSSLTGAADVLIALGVKIDIPPDAIGRCIHEAGVGFMFAPAHHPAM
KHVGPTRVELGTRTIFNLLGPLSNPAGVVRQMVGVFLPEWILPVAETLKALGTEHAWVVHGDGYDEITTTGETQVAELIG
GEIRSFTLTPEEVGLKRHTKDELRGGDAAYNANALRDMLDGAAGAYRDTVLMNAGAGLVIAGKATTLGDGIALAAQAIDS
GRALQVLDRLVEISNG
>Mature_335_residues
SALKTHIAKVAAGTALSFEEAREAFDIIMSGDATPGQIGGFLMALRVRGETVSEISGAVATMRAKMLRVEAPAGAIDIVG
TGGDNSHSVNISTGSAFVIAAAGVPVAKHGNRGLSSLTGAADVLIALGVKIDIPPDAIGRCIHEAGVGFMFAPAHHPAMK
HVGPTRVELGTRTIFNLLGPLSNPAGVVRQMVGVFLPEWILPVAETLKALGTEHAWVVHGDGYDEITTTGETQVAELIGG
EIRSFTLTPEEVGLKRHTKDELRGGDAAYNANALRDMLDGAAGAYRDTVLMNAGAGLVIAGKATTLGDGIALAAQAIDSG
RALQVLDRLVEISNG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=281, Percent_Identity=42.3487544483986, Blast_Score=221, Evalue=5e-59,
Organism=Saccharomyces cerevisiae, GI6320561, Length=331, Percent_Identity=29.0030211480363, Blast_Score=110, Evalue=4e-25,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_RHILO (Q98ME4)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102383.1
- ProteinModelPortal:   Q98ME4
- SMR:   Q98ME4
- GeneID:   1225046
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr0614
- NMPDR:   fig|266835.1.peg.488
- HOGENOM:   HBG559996
- OMA:   ATPSQMG
- ProtClustDB:   PRK00188
- BRENDA:   2.4.2.18
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 34609; Mature: 34478

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALKTHIAKVAAGTALSFEEAREAFDIIMSGDATPGQIGGFLMALRVRGETVSEISGAV
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHEEEEECCCHHHHHHHHH
ATMRAKMLRVEAPAGAIDIVGTGGDNSHSVNISTGSAFVIAAAGVPVAKHGNRGLSSLTG
HHHHHHHHEEECCCCEEEEEECCCCCCEEEEEECCCEEEEEECCCCEECCCCCCHHHHHH
AADVLIALGVKIDIPPDAIGRCIHEAGVGFMFAPAHHPAMKHVGPTRVELGTRTIFNLLG
HHHHHHHCCCEEECCHHHHHHHHHHHCCCEEECCCCCCHHHCCCCCEEHHHHHHHHHHHC
PLSNPAGVVRQMVGVFLPEWILPVAETLKALGTEHAWVVHGDGYDEITTTGETQVAELIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHC
GEIRSFTLTPEEVGLKRHTKDELRGGDAAYNANALRDMLDGAAGAYRDTVLMNAGAGLVI
CCCEEEEECHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHCCCCCHHHEEEEECCCCEEE
AGKATTLGDGIALAAQAIDSGRALQVLDRLVEISNG
ECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SALKTHIAKVAAGTALSFEEAREAFDIIMSGDATPGQIGGFLMALRVRGETVSEISGAV
CHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHEEEEECCCHHHHHHHHH
ATMRAKMLRVEAPAGAIDIVGTGGDNSHSVNISTGSAFVIAAAGVPVAKHGNRGLSSLTG
HHHHHHHHEEECCCCEEEEEECCCCCCEEEEEECCCEEEEEECCCCEECCCCCCHHHHHH
AADVLIALGVKIDIPPDAIGRCIHEAGVGFMFAPAHHPAMKHVGPTRVELGTRTIFNLLG
HHHHHHHCCCEEECCHHHHHHHHHHHCCCEEECCCCCCHHHCCCCCEEHHHHHHHHHHHC
PLSNPAGVVRQMVGVFLPEWILPVAETLKALGTEHAWVVHGDGYDEITTTGETQVAELIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHC
GEIRSFTLTPEEVGLKRHTKDELRGGDAAYNANALRDMLDGAAGAYRDTVLMNAGAGLVI
CCCEEEEECHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHCCCCCHHHEEEEECCCCEEE
AGKATTLGDGIALAAQAIDSGRALQVLDRLVEISNG
ECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968