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The map label for this gene is moeB [H]

Identifier: 15602560

GI number: 15602560

Start: 806372

End: 807088

Strand: Direct

Name: moeB [H]

Synonym: PM0695

Alternate gene names: 15602560

Gene position: 806372-807088 (Clockwise)

Preceding gene: 15602559

Following gene: 15602561

Centisome position: 35.72

GC content: 43.38

Gene sequence:

>717_bases
ATGACTGAATTAAGTTATCAAGAAGAATTACGTTATAACCGTCAAATTATGCTCAAGGCGGTAGATTTTGAGGGGCAAGA
AACCCTCAAACAAAGCAAAATGCTGATTGTTGGCTTAGGCGGTTTAGGCTGTGCGGCCAGCCAATATTTAACGACAGCTG
GTGTGGGGCATCTCACTTTGTTGGATTTTGATACGGTGTCGCTGTCGAACCTACAACGCCAGGTGTTGCACGATGACAGC
CGTTTAGCGATGCCGAAAGTCGATTCGGCAAAACTGTCGTTGCAACGCTTAAATCCACATATTCAGATTGACACTATCAA
TGCCAAACTCTCAACAGAAAAACTGGCTGAAATCATACCGCACTTTGATGTGATTTTAGATTGCACCGACAATATAGAAA
TTCGTAATCAGCTTGATCAGGTCTGCCAACAAGCGAAAGTGCCGTTAGTCTCTGGAGCGGCGATCCGCCTAGAAGGGCAA
GTAACGGTATTTACTTATCAAGAAAATACGCCAACCTATCGTACATTAAGTCAATTATTTGGCGAGAATACGCTAAGTTG
CGTCGAGGCGGGTGTATTAGCGCCCATTGTGGGCATTGTTGGTTCTATTCAAGCGCTAGAGGCAATTAAAGTGCGGTTAA
ATATCGGTAAGAATTTATGTGGCAGATTACTGATGATTGATGGGATGACGATGAATGTGAGAGAGATCAAATTTTAG

Upstream 100 bases:

>100_bases
GTGAAAAGTAACTGCTTTATTGTGCTAGAGCGTGAACGTGGCAATGTGGAAGCGGGTGAAACGGTCACAATCGAGCCATT
TAACCATCTAATGAGTTAAT

Downstream 100 bases:

>100_bases
TAAGGCAAATTTGCCTAATACTAAATATTCTGTACAATTTTATAACATGATTTTAATTAAATAATACAAAAACATTTCAT
GAAAATTATTGACAACATCA

Product: molybdopterin biosynthesis protein MoeB

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTELSYQEELRYNRQIMLKAVDFEGQETLKQSKMLIVGLGGLGCAASQYLTTAGVGHLTLLDFDTVSLSNLQRQVLHDDS
RLAMPKVDSAKLSLQRLNPHIQIDTINAKLSTEKLAEIIPHFDVILDCTDNIEIRNQLDQVCQQAKVPLVSGAAIRLEGQ
VTVFTYQENTPTYRTLSQLFGENTLSCVEAGVLAPIVGIVGSIQALEAIKVRLNIGKNLCGRLLMIDGMTMNVREIKF

Sequences:

>Translated_238_residues
MTELSYQEELRYNRQIMLKAVDFEGQETLKQSKMLIVGLGGLGCAASQYLTTAGVGHLTLLDFDTVSLSNLQRQVLHDDS
RLAMPKVDSAKLSLQRLNPHIQIDTINAKLSTEKLAEIIPHFDVILDCTDNIEIRNQLDQVCQQAKVPLVSGAAIRLEGQ
VTVFTYQENTPTYRTLSQLFGENTLSCVEAGVLAPIVGIVGSIQALEAIKVRLNIGKNLCGRLLMIDGMTMNVREIKF
>Mature_237_residues
TELSYQEELRYNRQIMLKAVDFEGQETLKQSKMLIVGLGGLGCAASQYLTTAGVGHLTLLDFDTVSLSNLQRQVLHDDSR
LAMPKVDSAKLSLQRLNPHIQIDTINAKLSTEKLAEIIPHFDVILDCTDNIEIRNQLDQVCQQAKVPLVSGAAIRLEGQV
TVFTYQENTPTYRTLSQLFGENTLSCVEAGVLAPIVGIVGSIQALEAIKVRLNIGKNLCGRLLMIDGMTMNVREIKF

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=228, Percent_Identity=39.9122807017544, Blast_Score=158, Evalue=4e-39,
Organism=Homo sapiens, GI4885649, Length=171, Percent_Identity=30.4093567251462, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI23510338, Length=166, Percent_Identity=27.1084337349398, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI23510340, Length=166, Percent_Identity=27.1084337349398, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1787048, Length=238, Percent_Identity=63.4453781512605, Blast_Score=322, Evalue=1e-89,
Organism=Escherichia coli, GI87082356, Length=229, Percent_Identity=39.7379912663755, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1789177, Length=126, Percent_Identity=26.1904761904762, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540406, Length=237, Percent_Identity=35.4430379746835, Blast_Score=174, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI193203301, Length=141, Percent_Identity=29.7872340425532, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321903, Length=231, Percent_Identity=37.6623376623377, Blast_Score=156, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6325438, Length=152, Percent_Identity=28.2894736842105, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582879, Length=238, Percent_Identity=44.5378151260504, Blast_Score=205, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24660640, Length=137, Percent_Identity=34.3065693430657, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28573937, Length=161, Percent_Identity=29.1925465838509, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 26317; Mature: 26186

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELSYQEELRYNRQIMLKAVDFEGQETLKQSKMLIVGLGGLGCAASQYLTTAGVGHLTL
CCCCCHHHHHHCCCEEEEEEECCCCHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCEEEE
LDFDTVSLSNLQRQVLHDDSRLAMPKVDSAKLSLQRLNPHIQIDTINAKLSTEKLAEIIP
EEECCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCC
HFDVILDCTDNIEIRNQLDQVCQQAKVPLVSGAAIRLEGQVTVFTYQENTPTYRTLSQLF
CCEEEEECCCCCHHHHHHHHHHHHHCCCEECCCEEEEECEEEEEEEECCCCHHHHHHHHH
GENTLSCVEAGVLAPIVGIVGSIQALEAIKVRLNIGKNLCGRLLMIDGMTMNVREIKF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHCEEEEECCCCCCCEEECC
>Mature Secondary Structure 
TELSYQEELRYNRQIMLKAVDFEGQETLKQSKMLIVGLGGLGCAASQYLTTAGVGHLTL
CCCCHHHHHHCCCEEEEEEECCCCHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCEEEE
LDFDTVSLSNLQRQVLHDDSRLAMPKVDSAKLSLQRLNPHIQIDTINAKLSTEKLAEIIP
EEECCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCC
HFDVILDCTDNIEIRNQLDQVCQQAKVPLVSGAAIRLEGQVTVFTYQENTPTYRTLSQLF
CCEEEEECCCCCHHHHHHHHHHHHHCCCEECCCEEEEECEEEEEEEECCCCHHHHHHHHH
GENTLSCVEAGVLAPIVGIVGSIQALEAIKVRLNIGKNLCGRLLMIDGMTMNVREIKF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHCEEEEECCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]