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The map label for this gene is moeA [H]

Identifier: 15602559

GI number: 15602559

Start: 805150

End: 806370

Strand: Direct

Name: moeA [H]

Synonym: PM0694

Alternate gene names: 15602559

Gene position: 805150-806370 (Clockwise)

Preceding gene: 15602557

Following gene: 15602560

Centisome position: 35.67

GC content: 45.45

Gene sequence:

>1221_bases
ATGTTGCCTCTTGAACAAGCACTGACTCAAATGCTCGCTATGTTGCCAACACCAGATTGTGCGCAAGCCGAACAACTCCC
CCTTCAACATGCGGTGAATCGCATTTGTGCTGAGGATATCATTTCCCCGCTTAATGTGCCCTCATTTGATAACTCGGCGA
TGGACGGCTATGCGGTGCGGCTGGCAGATTTAGCACAAAATTTAACTCTCACGGTCGCAGGAAAGTCCTTTGCGGGCGCA
CCTTTTGACGGGGAATGGCAAACACAAAGCACGGTCAGAATTATGACAGGAGCAATGTTGCCGGTGGGTGCGGATGCGGT
GGTGATGCAAGAAGACGTGATCGTCAATGAGGATGGTACAGTCACTTTCCCTGAAAAGATTAAAGCTGGTCAAAATATTC
GCTACATTGGCGAAGATGTCAAACAAGGTGAAGTGGTATTGAATAAAGGAAGCCTGTTAAATGCAGTTTCCTTACCCTTA
CTCGCCTCATTAGGCATAGATAACGTAAAGGTCTTTCCACGTTTGAAAGTAGCTGTGCTTTCGACTGGTGACGAACTTGT
GCCGGTAGGACAACCGCTGAAAGAAGGTCAAATTTACGACACTAACCGTTTCACGATTCAATTGTTACTGGAAAAGCTCA
ATTGTGAGATTCTGGATTTCGGTTTATTACCAGATAACGAGCAAGAATTTGAAAAAGCCTTTATTGAGGCTCAACAGCAA
GCGGACTTGGTGATCACAAGCGGTGGCGTTTCTGTGGGTGAAGCAGATTTTACCAAAAAAGTGCTTGAAAAAGTCGGTCA
AGTGAATTTCTGGAAAATTGCGATGAAGCCGGGTAAGCCTTTTGCCTTTGGTCGATTAAAAAACGCCTGGTTCTGTGGTT
TACCGGGTAATCCTGTGTCGGCATTGGCAACTTTTTATCAATTAGTACAACCGGTGATTGCCAAATTAAGTGGTTATAGC
CAGTGGAAAGCGCCGCAACGCTTGACAGCCATTGCAGCAACCAAGATGAAAAAAGCACCGGGGCGTTTAGATTTCCAACG
TGGTTTCTATCAAGTGAATGCCCAAGGGCAAATTGAGGTGCAACCCGTTGGTTTTCAAGGATCACATCTTTTTAGCTCTT
TTGTGAAAAGTAACTGCTTTATTGTGCTAGAGCGTGAACGTGGCAATGTGGAAGCGGGTGAAACGGTCACAATCGAGCCA
TTTAACCATCTAATGAGTTAA

Upstream 100 bases:

>100_bases
CTCACGCTCACATAAAATGTAAACAAAGTATGAGAAAAAGAGATCATCCTGCATTTTTGGTATAAAATATTGCCCGTTAA
ACTCAACTAAGGATTCAATT

Downstream 100 bases:

>100_bases
TATGACTGAATTAAGTTATCAAGAAGAATTACGTTATAACCGTCAAATTATGCTCAAGGCGGTAGATTTTGAGGGGCAAG
AAACCCTCAAACAAAGCAAA

Product: hypothetical protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MLPLEQALTQMLAMLPTPDCAQAEQLPLQHAVNRICAEDIISPLNVPSFDNSAMDGYAVRLADLAQNLTLTVAGKSFAGA
PFDGEWQTQSTVRIMTGAMLPVGADAVVMQEDVIVNEDGTVTFPEKIKAGQNIRYIGEDVKQGEVVLNKGSLLNAVSLPL
LASLGIDNVKVFPRLKVAVLSTGDELVPVGQPLKEGQIYDTNRFTIQLLLEKLNCEILDFGLLPDNEQEFEKAFIEAQQQ
ADLVITSGGVSVGEADFTKKVLEKVGQVNFWKIAMKPGKPFAFGRLKNAWFCGLPGNPVSALATFYQLVQPVIAKLSGYS
QWKAPQRLTAIAATKMKKAPGRLDFQRGFYQVNAQGQIEVQPVGFQGSHLFSSFVKSNCFIVLERERGNVEAGETVTIEP
FNHLMS

Sequences:

>Translated_406_residues
MLPLEQALTQMLAMLPTPDCAQAEQLPLQHAVNRICAEDIISPLNVPSFDNSAMDGYAVRLADLAQNLTLTVAGKSFAGA
PFDGEWQTQSTVRIMTGAMLPVGADAVVMQEDVIVNEDGTVTFPEKIKAGQNIRYIGEDVKQGEVVLNKGSLLNAVSLPL
LASLGIDNVKVFPRLKVAVLSTGDELVPVGQPLKEGQIYDTNRFTIQLLLEKLNCEILDFGLLPDNEQEFEKAFIEAQQQ
ADLVITSGGVSVGEADFTKKVLEKVGQVNFWKIAMKPGKPFAFGRLKNAWFCGLPGNPVSALATFYQLVQPVIAKLSGYS
QWKAPQRLTAIAATKMKKAPGRLDFQRGFYQVNAQGQIEVQPVGFQGSHLFSSFVKSNCFIVLERERGNVEAGETVTIEP
FNHLMS
>Mature_406_residues
MLPLEQALTQMLAMLPTPDCAQAEQLPLQHAVNRICAEDIISPLNVPSFDNSAMDGYAVRLADLAQNLTLTVAGKSFAGA
PFDGEWQTQSTVRIMTGAMLPVGADAVVMQEDVIVNEDGTVTFPEKIKAGQNIRYIGEDVKQGEVVLNKGSLLNAVSLPL
LASLGIDNVKVFPRLKVAVLSTGDELVPVGQPLKEGQIYDTNRFTIQLLLEKLNCEILDFGLLPDNEQEFEKAFIEAQQQ
ADLVITSGGVSVGEADFTKKVLEKVGQVNFWKIAMKPGKPFAFGRLKNAWFCGLPGNPVSALATFYQLVQPVIAKLSGYS
QWKAPQRLTAIAATKMKKAPGRLDFQRGFYQVNAQGQIEVQPVGFQGSHLFSSFVKSNCFIVLERERGNVEAGETVTIEP
FNHLMS

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=399, Percent_Identity=33.8345864661654, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI10880983, Length=399, Percent_Identity=33.8345864661654, Blast_Score=181, Evalue=1e-45,
Organism=Escherichia coli, GI1787049, Length=405, Percent_Identity=57.5308641975309, Blast_Score=462, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI25147659, Length=362, Percent_Identity=29.8342541436464, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17562606, Length=221, Percent_Identity=32.1266968325792, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17136978, Length=374, Percent_Identity=30.7486631016043, Blast_Score=144, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24638841, Length=374, Percent_Identity=30.7486631016043, Blast_Score=144, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 44287; Mature: 44287

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS01079 MOCF_BIOSYNTHESIS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPLEQALTQMLAMLPTPDCAQAEQLPLQHAVNRICAEDIISPLNVPSFDNSAMDGYAVR
CCCHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
LADLAQNLTLTVAGKSFAGAPFDGEWQTQSTVRIMTGAMLPVGADAVVMQEDVIVNEDGT
HHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCEEECCCCC
VTFPEKIKAGQNIRYIGEDVKQGEVVLNKGSLLNAVSLPLLASLGIDNVKVFPRLKVAVL
EECHHHHCCCCCEEECCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEECCEEEEEEE
STGDELVPVGQPLKEGQIYDTNRFTIQLLLEKLNCEILDFGLLPDNEQEFEKAFIEAQQQ
ECCCCEEECCCCCCCCEEEECCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCC
ADLVITSGGVSVGEADFTKKVLEKVGQVNFWKIAMKPGKPFAFGRLKNAWFCGLPGNPVS
CCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCEEECCCCCHHH
ALATFYQLVQPVIAKLSGYSQWKAPQRLTAIAATKMKKAPGRLDFQRGFYQVNAQGQIEV
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEE
QPVGFQGSHLFSSFVKSNCFIVLERERGNVEAGETVTIEPFNHLMS
EECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCHHHHCC
>Mature Secondary Structure
MLPLEQALTQMLAMLPTPDCAQAEQLPLQHAVNRICAEDIISPLNVPSFDNSAMDGYAVR
CCCHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
LADLAQNLTLTVAGKSFAGAPFDGEWQTQSTVRIMTGAMLPVGADAVVMQEDVIVNEDGT
HHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCEEECCCCC
VTFPEKIKAGQNIRYIGEDVKQGEVVLNKGSLLNAVSLPLLASLGIDNVKVFPRLKVAVL
EECHHHHCCCCCEEECCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEECCEEEEEEE
STGDELVPVGQPLKEGQIYDTNRFTIQLLLEKLNCEILDFGLLPDNEQEFEKAFIEAQQQ
ECCCCEEECCCCCCCCEEEECCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCC
ADLVITSGGVSVGEADFTKKVLEKVGQVNFWKIAMKPGKPFAFGRLKNAWFCGLPGNPVS
CCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCEEECCCCCHHH
ALATFYQLVQPVIAKLSGYSQWKAPQRLTAIAATKMKKAPGRLDFQRGFYQVNAQGQIEV
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEE
QPVGFQGSHLFSSFVKSNCFIVLERERGNVEAGETVTIEPFNHLMS
EECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]