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The map label for this gene is mtgA

Identifier: 15602189

GI number: 15602189

Start: 379224

End: 379964

Strand: Reverse

Name: mtgA

Synonym: PM0324

Alternate gene names: 15602189

Gene position: 379964-379224 (Counterclockwise)

Preceding gene: 15602190

Following gene: 15602180

Centisome position: 16.83

GC content: 42.24

Gene sequence:

>741_bases
ATGAGCAAGCTAAAAAAGACTAAGCATCCTTTTCCTTGTTTCAGTATTTGGCAACAATTTAAACGCAAACTTTACCGCAC
TTTTGCACTATTTCTCGTGCTGTTTCTTTCAAGTGTGGTACTGTTTCGTTTCGTACCCGTTCCGTTTTCTGCCTATATGC
TACAGCAAAAAATAGGCTATCTGTTTGAAGGGAATTTGAGTAGCACGATCCATTATCAATGGGTCCCTCTTGAGCAAATA
AGTCAATCCATGCAGTTAGCCGTCATTGCTAGCGAAGATCAACGCTTTGCGACCCATTATGGCTTTGATTGGGACGCCAT
TCAATCTGCTTTACAACACAATCAACGCGGAAAAAGAATCCGCGGAGGCTCAACCATCAGCCAGCAAACAGCTAAAAATC
TATACTTGTGGCATGGGCAAAGTTGGTTGCGCAAAGCTATTGAGATGCCTACCACGCTCGTGCTTGAAACCCTTTGGTCT
AAAAAACGCATTCTGGAAGTCTATCTTAATATTGCTGAATTTGGACCGAATATTTTTGGTGTAGAAGCCGCCAGTCAGCA
TTATTTTCGCAAACCGGCTAAACAGTTAAGCAATGCTGAAGCCGCATTACTCGCGGCAGTACTTCCAAACCCGATTATCT
TCAAAGTGAACAAACCCAGTGCTTATGTGAAAAAAAGACAACAGCATATTCAGCGTCAAATGGGGTTGTTAGGAAAGCAG
CATTTAAGTCAGTTAGATTAG

Upstream 100 bases:

>100_bases
CAGCAAAATCTCAATACCAGCGCAGCCACCATTACTCGTGGCTCAAATATGATTAAAACCATGCCACCTGAATTTATGGC
GTGGGTAAAAGAACAATTAG

Downstream 100 bases:

>100_bases
CGCTATGCTGAAAGTGCGGTCGATTTTAGGTCAGTTTTCTTAAAGAGAAAGGCTCAACTTTGTTGAGCCTTTTGTTTATT
CTTCACGCGCGTGGTTTAAA

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MSKLKKTKHPFPCFSIWQQFKRKLYRTFALFLVLFLSSVVLFRFVPVPFSAYMLQQKIGYLFEGNLSSTIHYQWVPLEQI
SQSMQLAVIASEDQRFATHYGFDWDAIQSALQHNQRGKRIRGGSTISQQTAKNLYLWHGQSWLRKAIEMPTTLVLETLWS
KKRILEVYLNIAEFGPNIFGVEAASQHYFRKPAKQLSNAEAALLAAVLPNPIIFKVNKPSAYVKKRQQHIQRQMGLLGKQ
HLSQLD

Sequences:

>Translated_246_residues
MSKLKKTKHPFPCFSIWQQFKRKLYRTFALFLVLFLSSVVLFRFVPVPFSAYMLQQKIGYLFEGNLSSTIHYQWVPLEQI
SQSMQLAVIASEDQRFATHYGFDWDAIQSALQHNQRGKRIRGGSTISQQTAKNLYLWHGQSWLRKAIEMPTTLVLETLWS
KKRILEVYLNIAEFGPNIFGVEAASQHYFRKPAKQLSNAEAALLAAVLPNPIIFKVNKPSAYVKKRQQHIQRQMGLLGKQ
HLSQLD
>Mature_245_residues
SKLKKTKHPFPCFSIWQQFKRKLYRTFALFLVLFLSSVVLFRFVPVPFSAYMLQQKIGYLFEGNLSSTIHYQWVPLEQIS
QSMQLAVIASEDQRFATHYGFDWDAIQSALQHNQRGKRIRGGSTISQQTAKNLYLWHGQSWLRKAIEMPTTLVLETLWSK
KRILEVYLNIAEFGPNIFGVEAASQHYFRKPAKQLSNAEAALLAAVLPNPIIFKVNKPSAYVKKRQQHIQRQMGLLGKQH
LSQLD

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=225, Percent_Identity=55.5555555555556, Blast_Score=251, Evalue=3e-68,
Organism=Escherichia coli, GI87082258, Length=142, Percent_Identity=38.7323943661972, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786343, Length=147, Percent_Identity=34.0136054421769, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788867, Length=136, Percent_Identity=38.2352941176471, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_PASMU (Q9CNV0)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245261.1
- ProteinModelPortal:   Q9CNV0
- SMR:   Q9CNV0
- GeneID:   1243671
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0324
- NMPDR:   fig|272843.1.peg.324
- HOGENOM:   HBG685698
- OMA:   RQMSQLG
- ProtClustDB:   PRK00056
- BioCyc:   PMUL272843:PM0324-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 28486; Mature: 28354

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc390d28)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLKKTKHPFPCFSIWQQFKRKLYRTFALFLVLFLSSVVLFRFVPVPFSAYMLQQKIGY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCH
LFEGNLSSTIHYQWVPLEQISQSMQLAVIASEDQRFATHYGFDWDAIQSALQHNQRGKRI
HEECCCCCEEEEEECCHHHHHHHHEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHCCCEE
RGGSTISQQTAKNLYLWHGQSWLRKAIEMPTTLVLETLWSKKRILEVYLNIAEFGPNIFG
CCCCCHHHHHHHCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VEAASQHYFRKPAKQLSNAEAALLAAVLPNPIIFKVNKPSAYVKKRQQHIQRQMGLLGKQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
HLSQLD
HHHHCH
>Mature Secondary Structure 
SKLKKTKHPFPCFSIWQQFKRKLYRTFALFLVLFLSSVVLFRFVPVPFSAYMLQQKIGY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCH
LFEGNLSSTIHYQWVPLEQISQSMQLAVIASEDQRFATHYGFDWDAIQSALQHNQRGKRI
HEECCCCCEEEEEECCHHHHHHHHEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHCCCEE
RGGSTISQQTAKNLYLWHGQSWLRKAIEMPTTLVLETLWSKKRILEVYLNIAEFGPNIFG
CCCCCHHHHHHHCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VEAASQHYFRKPAKQLSNAEAALLAAVLPNPIIFKVNKPSAYVKKRQQHIQRQMGLLGKQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
HLSQLD
HHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100