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The map label for this gene is suhB

Identifier: 15602180

GI number: 15602180

Start: 371754

End: 372557

Strand: Reverse

Name: suhB

Synonym: PM0315

Alternate gene names: 15602180

Gene position: 372557-371754 (Counterclockwise)

Preceding gene: 15602189

Following gene: 15602167

Centisome position: 16.5

GC content: 40.67

Gene sequence:

>804_bases
ATGAATCCAATGTTAAATATCGCGATTCGTGCGGCACGAAAAGCGGGCAATGTAATTGCTAAAGGTTATGAGCGCCGTGA
TGATCTTCAAACAACGCTAAAAAGCACAAACGATTATGTGACAAATATTGATAAAGCTTCTGAAGAAGCCATTATTGAAG
TGATTAGAAAATCGTACCCGGATCACACAATTATTACGGAAGAAAGTGGTGCGTTAGAAGGTAAAGATAGCGATATTCAA
TGGGTGATTGATCCACTAGATGGCACCACAAACTTTGTTAAAGGTTTACCGCATTTTTCTGTTTCTATTGCTATTCGTGT
CAAAGGTCGCACCGAAGTGGGTGTGGTTTACGATCCTATCCGTAACGAATTATTCACCGCAGTACGTGGTGAAGGCGCTA
AAATTAATGACATGCGTTTACGCGTTGAAAATAAACGCGACTTAGCTGGTACCGTGTTAACAACAGGTTTTCCTTTTAAA
CAAACGCGCTTAATGCCAATGCAATTTGCGATGATGAATAACTTAATTCAAGATTGTGCTGATTTCCGTCGCATGGGCTC
TGCGGCATTAGACTTATGCTATGTTGCTGCGGGACGCGTTGATGGTTATTTTGAAGTCGGTGTTAAAGCTTGGGATATTG
CTGCAGGCGACTTGATCGTACGTGAAGCTGGCGGGTTAGTTTGTGATTTTAATGGTGGGCATAGCTATTTAACATCAGGT
CATCTTGTTGCTGCAGCACCTCGTATTGTGAAAGAAATCTTAAATAAAATTCAACCTTGTCTGTCTGACGAATTTAAAAA
ATAA

Upstream 100 bases:

>100_bases
CACGATAAGAATAAAAGAGGTGAAAATTTCTCTCGCCATTTTTAATGAAATTCCCTATAATACCCGCCACTTTTCTGTTC
TTTAAAATCTGGTGGAAACA

Downstream 100 bases:

>100_bases
GTTTAATACATTTAAGTGATCAAAAAATCCCTCAATAATGCGTTATTGAGGGATTTTTTTAGTTTATAAATCGCGTAGCA
ATGTACGACGTTGCGGTCTG

Product: hypothetical protein

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MNPMLNIAIRAARKAGNVIAKGYERRDDLQTTLKSTNDYVTNIDKASEEAIIEVIRKSYPDHTIITEESGALEGKDSDIQ
WVIDPLDGTTNFVKGLPHFSVSIAIRVKGRTEVGVVYDPIRNELFTAVRGEGAKINDMRLRVENKRDLAGTVLTTGFPFK
QTRLMPMQFAMMNNLIQDCADFRRMGSAALDLCYVAAGRVDGYFEVGVKAWDIAAGDLIVREAGGLVCDFNGGHSYLTSG
HLVAAAPRIVKEILNKIQPCLSDEFKK

Sequences:

>Translated_267_residues
MNPMLNIAIRAARKAGNVIAKGYERRDDLQTTLKSTNDYVTNIDKASEEAIIEVIRKSYPDHTIITEESGALEGKDSDIQ
WVIDPLDGTTNFVKGLPHFSVSIAIRVKGRTEVGVVYDPIRNELFTAVRGEGAKINDMRLRVENKRDLAGTVLTTGFPFK
QTRLMPMQFAMMNNLIQDCADFRRMGSAALDLCYVAAGRVDGYFEVGVKAWDIAAGDLIVREAGGLVCDFNGGHSYLTSG
HLVAAAPRIVKEILNKIQPCLSDEFKK
>Mature_267_residues
MNPMLNIAIRAARKAGNVIAKGYERRDDLQTTLKSTNDYVTNIDKASEEAIIEVIRKSYPDHTIITEESGALEGKDSDIQ
WVIDPLDGTTNFVKGLPHFSVSIAIRVKGRTEVGVVYDPIRNELFTAVRGEGAKINDMRLRVENKRDLAGTVLTTGFPFK
QTRLMPMQFAMMNNLIQDCADFRRMGSAALDLCYVAAGRVDGYFEVGVKAWDIAAGDLIVREAGGLVCDFNGGHSYLTSG
HLVAAAPRIVKEILNKIQPCLSDEFKK

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family

Homologues:

Organism=Homo sapiens, GI5031789, Length=261, Percent_Identity=36.3984674329502, Blast_Score=161, Evalue=5e-40,
Organism=Homo sapiens, GI221625487, Length=258, Percent_Identity=36.046511627907, Blast_Score=161, Evalue=5e-40,
Organism=Homo sapiens, GI7657236, Length=249, Percent_Identity=36.9477911646586, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI221625507, Length=146, Percent_Identity=36.986301369863, Blast_Score=101, Evalue=7e-22,
Organism=Escherichia coli, GI1788882, Length=267, Percent_Identity=64.0449438202247, Blast_Score=373, Evalue=1e-105,
Organism=Escherichia coli, GI1790659, Length=133, Percent_Identity=33.0827067669173, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193202572, Length=266, Percent_Identity=32.7067669172932, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI193202570, Length=269, Percent_Identity=33.0855018587361, Blast_Score=144, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6320493, Length=208, Percent_Identity=35.5769230769231, Blast_Score=123, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6321836, Length=241, Percent_Identity=31.9502074688797, Blast_Score=115, Evalue=9e-27,
Organism=Drosophila melanogaster, GI21357329, Length=270, Percent_Identity=37.7777777777778, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI21357303, Length=248, Percent_Identity=35.0806451612903, Blast_Score=147, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24664922, Length=259, Percent_Identity=30.5019305019305, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24664926, Length=233, Percent_Identity=30.4721030042918, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI21357957, Length=262, Percent_Identity=29.7709923664122, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24664918, Length=240, Percent_Identity=35, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SUHB_PASMU (Q9CNV8)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245252.1
- ProteinModelPortal:   Q9CNV8
- SMR:   Q9CNV8
- PRIDE:   Q9CNV8
- GeneID:   1243662
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0315
- NMPDR:   fig|272843.1.peg.315
- HOGENOM:   HBG730251
- OMA:   TGFPFKQ
- ProtClustDB:   CLSK870048
- BioCyc:   PMUL272843:PM0315-MONOMER
- BRENDA:   3.1.3.25
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337
- PANTHER:   PTHR20854
- PRINTS:   PR00377
- PRINTS:   PR01959

Pfam domain/function: PF00459 Inositol_P

EC number: =3.1.3.25

Molecular weight: Translated: 29470; Mature: 29470

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00629 IMP_1; PS00630 IMP_2

Important sites: BINDING 67-67 BINDING 183-183 BINDING 212-212

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPMLNIAIRAARKAGNVIAKGYERRDDLQTTLKSTNDYVTNIDKASEEAIIEVIRKSYP
CCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHCCC
DHTIITEESGALEGKDSDIQWVIDPLDGTTNFVKGLPHFSVSIAIRVKGRTEVGVVYDPI
CCEEEECCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCEEEEEEEEECCCCEEEEEECHH
RNELFTAVRGEGAKINDMRLRVENKRDLAGTVLTTGFPFKQTRLMPMQFAMMNNLIQDCA
HHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEEECCCCCHHCCCCHHHHHHHHHHHHHHH
DFRRMGSAALDLCYVAAGRVDGYFEVGVKAWDIAAGDLIVREAGGLVCDFNGGHSYLTSG
HHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCEEEEECCCEEEEECCCCCEEECC
HLVAAAPRIVKEILNKIQPCLSDEFKK
CHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPMLNIAIRAARKAGNVIAKGYERRDDLQTTLKSTNDYVTNIDKASEEAIIEVIRKSYP
CCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHCCC
DHTIITEESGALEGKDSDIQWVIDPLDGTTNFVKGLPHFSVSIAIRVKGRTEVGVVYDPI
CCEEEECCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCEEEEEEEEECCCCEEEEEECHH
RNELFTAVRGEGAKINDMRLRVENKRDLAGTVLTTGFPFKQTRLMPMQFAMMNNLIQDCA
HHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEEECCCCCHHCCCCHHHHHHHHHHHHHHH
DFRRMGSAALDLCYVAAGRVDGYFEVGVKAWDIAAGDLIVREAGGLVCDFNGGHSYLTSG
HHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCEEEEECCCEEEEECCCCCEEECC
HLVAAAPRIVKEILNKIQPCLSDEFKK
CHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100