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The map label for this gene is tenA

Identifier: 15673761

GI number: 15673761

Start: 1838686

End: 1839342

Strand: Reverse

Name: tenA

Synonym: L0228

Alternate gene names: 15673761

Gene position: 1839342-1838686 (Counterclockwise)

Preceding gene: 30024054

Following gene: 15673760

Centisome position: 77.75

GC content: 35.62

Gene sequence:

>657_bases
ATGTTATTTACTGAATTAGCAAGAGAAAAATCATCAATATTTTGGGAAAGAAGTTTTGAGCATCCTTTTATTCAAGGATT
AGTGAGTGGAGAATTAGCTCCTGAGGTTTTTCGCTATTATTTGTTGCAAGACCGTTATTATCTTGAACATTTTAGTAAGT
TATATTTTCTTATTGCCAAGAAATCTGCTAGTGAAGAGATTCAAGCACATTTAAGATTAAATGCCGAAGAACTAAAAAAT
GGAGAGATTTTTGTTCGCGAGGGATTTTTTAAAGAATTAGAGATTGGTGAACAAGAAATTTTAGAAACGCCGGTTGCTCC
CACTGCTTATCATTATGTTTCTCATATGTATCGTCAGCTTATTGATGGCTCTGTCAATAGTGCAATTGCGGGAATGTTGC
CTTGTGCTTGGCTATATCATGAAATTGGTTTACGATTAATTGAGGTGGGGTCGCCCAATCCTTTGTATCAAAAATGGATT
GAAACCTATGCGAGTGAAGAAGCTACCGTCCAAATCGCAAAAGAGTGTGATATTATTAATCGGCTTTATCAAGAAAGTGA
TGAACAAGAGCAAGAACAGATGCTTGAGGCTTTTTTGATTAGTAGTAAAATGGAGGCTGATTTTTGGGAAATGGCTTTGG
TCTTAGAAAAATGGTAG

Upstream 100 bases:

>100_bases
TCAAGTGCAGCTCCGCTTTTAATCCAAATTGTCATCGACATTGGCAAGTTTATTTTAATGAATAGGCATATGTTTTTAAT
ATTATGAAGGAAGAAATGAA

Downstream 100 bases:

>100_bases
TTGAAATTTTTCTGTAAAAGTTAAAAAGTCTTATATGACTTCTAATATAAAAAAAGATTAAATCTATATCAGTTAATTCT
TGCAAACGGATACACAAAAT

Product: TenA

Products: NA

Alternate protein names: Thiaminase II; Transcriptional activator tenA [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MLFTELAREKSSIFWERSFEHPFIQGLVSGELAPEVFRYYLLQDRYYLEHFSKLYFLIAKKSASEEIQAHLRLNAEELKN
GEIFVREGFFKELEIGEQEILETPVAPTAYHYVSHMYRQLIDGSVNSAIAGMLPCAWLYHEIGLRLIEVGSPNPLYQKWI
ETYASEEATVQIAKECDIINRLYQESDEQEQEQMLEAFLISSKMEADFWEMALVLEKW

Sequences:

>Translated_218_residues
MLFTELAREKSSIFWERSFEHPFIQGLVSGELAPEVFRYYLLQDRYYLEHFSKLYFLIAKKSASEEIQAHLRLNAEELKN
GEIFVREGFFKELEIGEQEILETPVAPTAYHYVSHMYRQLIDGSVNSAIAGMLPCAWLYHEIGLRLIEVGSPNPLYQKWI
ETYASEEATVQIAKECDIINRLYQESDEQEQEQMLEAFLISSKMEADFWEMALVLEKW
>Mature_218_residues
MLFTELAREKSSIFWERSFEHPFIQGLVSGELAPEVFRYYLLQDRYYLEHFSKLYFLIAKKSASEEIQAHLRLNAEELKN
GEIFVREGFFKELEIGEQEILETPVAPTAYHYVSHMYRQLIDGSVNSAIAGMLPCAWLYHEIGLRLIEVGSPNPLYQKWI
ETYASEEATVQIAKECDIINRLYQESDEQEQEQMLEAFLISSKMEADFWEMALVLEKW

Specific function: Stimulates the production of several extracellular degradative enzymes at the transcriptional level, probably by interfering with degS and degU, which are required for this effect. Is not an essential protein, but affects the sporulation frequency [H]

COG id: COG0819

COG function: function code K; Putative transcription activator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiaminase-2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016084
- InterPro:   IPR004305 [H]

Pfam domain/function: PF03070 TENA_THI-4 [H]

EC number: =3.5.99.2 [H]

Molecular weight: Translated: 25609; Mature: 25609

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFTELAREKSSIFWERSFEHPFIQGLVSGELAPEVFRYYLLQDRYYLEHFSKLYFLIAK
CCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
KSASEEIQAHLRLNAEELKNGEIFVREGFFKELEIGEQEILETPVAPTAYHYVSHMYRQL
CCHHHHHHHHHCCCHHHCCCCCEEEECCCHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHH
IDGSVNSAIAGMLPCAWLYHEIGLRLIEVGSPNPLYQKWIETYASEEATVQIAKECDIIN
HCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
RLYQESDEQEQEQMLEAFLISSKMEADFWEMALVLEKW
HHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLFTELAREKSSIFWERSFEHPFIQGLVSGELAPEVFRYYLLQDRYYLEHFSKLYFLIAK
CCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
KSASEEIQAHLRLNAEELKNGEIFVREGFFKELEIGEQEILETPVAPTAYHYVSHMYRQL
CCHHHHHHHHHCCCHHHCCCCCEEEECCCHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHH
IDGSVNSAIAGMLPCAWLYHEIGLRLIEVGSPNPLYQKWIETYASEEATVQIAKECDIIN
HCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
RLYQESDEQEQEQMLEAFLISSKMEADFWEMALVLEKW
HHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1898926; 9384377 [H]