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The map label for this gene is atpD

Identifier: 15673746

GI number: 15673746

Start: 1823212

End: 1824621

Strand: Reverse

Name: atpD

Synonym: L6563

Alternate gene names: 15673746

Gene position: 1824621-1823212 (Counterclockwise)

Preceding gene: 15673747

Following gene: 15673745

Centisome position: 77.13

GC content: 42.62

Gene sequence:

>1410_bases
TTGAGTTCTGGTAAAATTACTCAGATTATCGGTCCCGTCGTTGACGTGGAATTTGGTTCTGATGCCAAATTGCCTGAGAT
TAACAATGCCTTGATTGTCTACAAAGATGTCAATGGCCTAAAAACAAAAATTACTCTTGAAGTTGCTTTGGAACTTGGTG
ATGGTGCAGTTCGTACAATCGCTATGGAATCTACTGATGGCTTGACTCGTGGACTTGAAGTCCTTGATACAGGTAAAGCA
GTCAGCGTTCCTGTTGGGGAAGCCACTCTTGGTCGTGTTTTTAACGTTCTTGGTGATGTTATTGACGGTGGGGAAGAATT
TGCTGCTGATGCAGAACGTAATCCTATCCATAAAAAAGCTCCAACATTTGACGAATTGTCAACTGCAAACGAAGTTCTCG
TAACTGGGATTAAAGTTGTCGATTTGCTTGCACCTTACCTTAAAGGTGGTAAAGTTGGACTTTTCGGTGGTGCCGGAGTT
GGTAAAACCGTCCTTATTCAAGAATTGATTCACAACATCGCCCAAGAACACGGAGGTATTTCTGTGTTTACCGGTGTTGG
GGAACGTACTCGTGAAGGGAATGACCTTTACTGGGAAATGAAAGAATCAGGCGTTATTGAAAAAACTGCCATGGTCTTTG
GTCAAATGAATGAACCACCAGGAGCACGTATGCGTGTTGCCCTTACTGGTTTGACAATTGCTGAATATTTCCGTGATGTT
CAAGGTCAAGACGTACTGCTTTTCATTGACAACATCTTCCGTTTCACACAAGCTGGTTCAGAAGTTTCTGCCCTTTTGGG
ACGTATGCCTTCTGCCGTTGGTTACCAACCAACACTTGCTACTGAAATGGGGCAATTGCAAGAACGTATCACTTCTACTA
AGAAGGGTTCTGTTACATCTATCCAAGCGATTTATGTCCCTGCCGATGACTATACTGACCCAGCGCCAGCTACAGCCTTC
GCTCACTTGGATGCAACAACTAACTTGGAACGTCGTTTGACACAAATGGGTATTTATCCAGCCGTTGACCCACTTGCTTC
ATCATCACGTGCGCTTACACCTGAAATTGTTGGTGAAGAACACTATGAAGTGGCAATGGAAGTTCAACGTGTCCTCCAAC
GTTATAAAGAATTGCAAGATATTATTGCCATTCTTGGTATGGATGAATTGTCTGACGATGAAAAAATTCTCGTTGGACGT
GCACGTCGTATCCAATTCTTCCTTTCACAAAACTTCCACGTTGCGGAACAATTTACTGGTCAACCTGGTTCATATGTACC
AATTGACAAAACTGTTCATGACTTCAAAGAAATTTTGGAAGGTAAATATGACGAAGTCCCTGAAGATGCTTTCCGTGGTG
TAGGTCCAATTGAAGATGTACTCGAAAAAGCAAAATCAATGGGTTATTAA

Upstream 100 bases:

>100_bases
TGAATCTTAATTGTTTTTGTCAGTAAAATTTTTACTGACAAACATAAAAATGAATAGAAATTCTGTTCTTTGACAGAAAA
TAAAAACAGGAGGAAAAACA

Downstream 100 bases:

>100_bases
TTCGATTTCTGATGAATTGAGAAAGTGAAAATACTCTATTGACTAAAAAAATTACTGACAAAAAATTCTGTCAGTAAAAG
TTGATTGAATTGTAAAATTT

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MSSGKITQIIGPVVDVEFGSDAKLPEINNALIVYKDVNGLKTKITLEVALELGDGAVRTIAMESTDGLTRGLEVLDTGKA
VSVPVGEATLGRVFNVLGDVIDGGEEFAADAERNPIHKKAPTFDELSTANEVLVTGIKVVDLLAPYLKGGKVGLFGGAGV
GKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDV
QGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAF
AHLDATTNLERRLTQMGIYPAVDPLASSSRALTPEIVGEEHYEVAMEVQRVLQRYKELQDIIAILGMDELSDDEKILVGR
ARRIQFFLSQNFHVAEQFTGQPGSYVPIDKTVHDFKEILEGKYDEVPEDAFRGVGPIEDVLEKAKSMGY

Sequences:

>Translated_469_residues
MSSGKITQIIGPVVDVEFGSDAKLPEINNALIVYKDVNGLKTKITLEVALELGDGAVRTIAMESTDGLTRGLEVLDTGKA
VSVPVGEATLGRVFNVLGDVIDGGEEFAADAERNPIHKKAPTFDELSTANEVLVTGIKVVDLLAPYLKGGKVGLFGGAGV
GKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDV
QGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAF
AHLDATTNLERRLTQMGIYPAVDPLASSSRALTPEIVGEEHYEVAMEVQRVLQRYKELQDIIAILGMDELSDDEKILVGR
ARRIQFFLSQNFHVAEQFTGQPGSYVPIDKTVHDFKEILEGKYDEVPEDAFRGVGPIEDVLEKAKSMGY
>Mature_468_residues
SSGKITQIIGPVVDVEFGSDAKLPEINNALIVYKDVNGLKTKITLEVALELGDGAVRTIAMESTDGLTRGLEVLDTGKAV
SVPVGEATLGRVFNVLGDVIDGGEEFAADAERNPIHKKAPTFDELSTANEVLVTGIKVVDLLAPYLKGGKVGLFGGAGVG
KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVQ
GQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFA
HLDATTNLERRLTQMGIYPAVDPLASSSRALTPEIVGEEHYEVAMEVQRVLQRYKELQDIIAILGMDELSDDEKILVGRA
RRIQFFLSQNFHVAEQFTGQPGSYVPIDKTVHDFKEILEGKYDEVPEDAFRGVGPIEDVLEKAKSMGY

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=477, Percent_Identity=65.4088050314465, Blast_Score=612, Evalue=1e-175,
Organism=Homo sapiens, GI19913424, Length=349, Percent_Identity=27.2206303724928, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI19913428, Length=342, Percent_Identity=25.4385964912281, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI19913426, Length=361, Percent_Identity=24.9307479224377, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI50345984, Length=348, Percent_Identity=27.0114942528736, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4757810, Length=348, Percent_Identity=27.0114942528736, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1790170, Length=467, Percent_Identity=63.8115631691649, Blast_Score=591, Evalue=1e-170,
Organism=Escherichia coli, GI1788251, Length=316, Percent_Identity=31.0126582278481, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790172, Length=319, Percent_Identity=28.5266457680251, Blast_Score=109, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=477, Percent_Identity=62.8930817610063, Blast_Score=588, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI17565854, Length=358, Percent_Identity=29.3296089385475, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17570191, Length=399, Percent_Identity=24.3107769423559, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17510931, Length=404, Percent_Identity=24.2574257425743, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71988080, Length=349, Percent_Identity=26.9340974212034, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=349, Percent_Identity=26.9340974212034, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988074, Length=412, Percent_Identity=25, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322581, Length=464, Percent_Identity=67.8879310344828, Blast_Score=609, Evalue=1e-175,
Organism=Saccharomyces cerevisiae, GI6319603, Length=419, Percent_Identity=24.582338902148, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6319370, Length=378, Percent_Identity=28.042328042328, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320016, Length=280, Percent_Identity=26.0714285714286, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24638766, Length=473, Percent_Identity=65.53911205074, Blast_Score=605, Evalue=1e-173,
Organism=Drosophila melanogaster, GI28574560, Length=470, Percent_Identity=64.2553191489362, Blast_Score=585, Evalue=1e-167,
Organism=Drosophila melanogaster, GI20129479, Length=347, Percent_Identity=27.0893371757925, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24583988, Length=353, Percent_Identity=28.0453257790368, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24583986, Length=353, Percent_Identity=28.0453257790368, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24583984, Length=353, Percent_Identity=28.0453257790368, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24583992, Length=349, Percent_Identity=26.9340974212034, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281361666, Length=409, Percent_Identity=24.9388753056235, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646341, Length=409, Percent_Identity=24.9388753056235, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17136796, Length=409, Percent_Identity=24.9388753056235, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24658560, Length=363, Percent_Identity=26.9972451790634, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24638768, Length=96, Percent_Identity=52.0833333333333, Blast_Score=90, Evalue=4e-18,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_LACLA (Q9CES0)

Other databases:

- EMBL:   AF393838
- EMBL:   AB072443
- EMBL:   AE005176
- PIR:   D86845
- RefSeq:   NP_267920.1
- ProteinModelPortal:   Q9CES0
- SMR:   Q9CES0
- GeneID:   1115427
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L6563
- NMPDR:   fig|272623.1.peg.1808
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- ProtClustDB:   PRK09280
- BioCyc:   LLAC272623:L6563-MONOMER
- BRENDA:   3.6.3.14
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 50912; Mature: 50780

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGKITQIIGPVVDVEFGSDAKLPEINNALIVYKDVNGLKTKITLEVALELGDGAVRTI
CCCCCCHHHHCCEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEEEEEEEECCCCCEEEE
AMESTDGLTRGLEVLDTGKAVSVPVGEATLGRVFNVLGDVIDGGEEFAADAERNPIHKKA
EECCCCCHHHCHHHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCC
PTFDELSTANEVLVTGIKVVDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCE
SVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDV
EEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHHCC
QGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTS
CCCEEEEEHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEE
IQAIYVPADDYTDPAPATAFAHLDATTNLERRLTQMGIYPAVDPLASSSRALTPEIVGEE
EEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCH
HYEVAMEVQRVLQRYKELQDIIAILGMDELSDDEKILVGRARRIQFFLSQNFHVAEQFTG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHEEEECCCCCEEHHHHCC
QPGSYVPIDKTVHDFKEILEGKYDEVPEDAFRGVGPIEDVLEKAKSMGY
CCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SSGKITQIIGPVVDVEFGSDAKLPEINNALIVYKDVNGLKTKITLEVALELGDGAVRTI
CCCCCHHHHCCEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEEEEEEEECCCCCEEEE
AMESTDGLTRGLEVLDTGKAVSVPVGEATLGRVFNVLGDVIDGGEEFAADAERNPIHKKA
EECCCCCHHHCHHHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCC
PTFDELSTANEVLVTGIKVVDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCE
SVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDV
EEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHHCC
QGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTS
CCCEEEEEHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEE
IQAIYVPADDYTDPAPATAFAHLDATTNLERRLTQMGIYPAVDPLASSSRALTPEIVGEE
EEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCH
HYEVAMEVQRVLQRYKELQDIIAILGMDELSDDEKILVGRARRIQFFLSQNFHVAEQFTG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHEEEECCCCCEEHHHHCC
QPGSYVPIDKTVHDFKEILEGKYDEVPEDAFRGVGPIEDVLEKAKSMGY
CCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471