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The map label for this gene is yriD

Identifier: 15673713

GI number: 15673713

Start: 1788237

End: 1789658

Strand: Reverse

Name: yriD

Synonym: L171588

Alternate gene names: 15673713

Gene position: 1789658-1788237 (Counterclockwise)

Preceding gene: 15673718

Following gene: 15673712

Centisome position: 75.65

GC content: 38.12

Gene sequence:

>1422_bases
GTGAACAAGTTCTTTAAACTTGAAGAAAACGGCACAACAGTTGGCCGTGAAATAATGGCTGGTTTGACTACATTCTTTGC
TATGAGTTATATCCTCTTTGTTAACCCACAAGTTTTGGGTACAACAGGAATGCCTGTCCAAGCAGTTTTCTTAGCAACTA
TTTTGGCCTCTATTGTTGGGACACTTGCAATTGCCTTAATCGCTAATGTTCCCTACGCTTTGGCACCCGGAATGGGTCTA
AATGCATTCTTTGCTTACACTGTTGTATTATCTCTTGGTTATACTTGGCAAGAAGCTTTGGCAATGGTCTTCATTTGTGG
GATTATCAATATTATTATTACTTTTACTTCCATTCGTAAAGCAATCATTCTTGGAATTCCTGAAAGTTTACAACACGCAA
TTGGTGGTGGTATCGGTATTTTCATTGCCTATATTGGGATTAAAAATGCAGGAATTTTGCGTTTTATCGCTGACCCAGGA
ACTTATGTGAACAACCATGGAACTATTACAGCAAATTCATCAATTGTTCCAGAACTTGTAACTTTTAATAACCCAGGCGT
ATTAGTCGCACTTGTTGGGATTGTAGTGACAATGTTCTTTGTTATTCGTAAATGGCGTGCAGGAATTTTACTTTCAATCT
TAGTAACAACTATCCTAGCTCTTTTGACTGGTGTAGTTAAAGTTGATGTGAATACTTTATTTGCTGAAAACAACTTAGGA
ACAGCTATCAATCAAATGGGAACAACCTTTGGTGCTGCTTTTGGTCCAAAAGGTTTTGGCTCTTTATTCTCAGACTCATC
ACGTTATATTGAAGTTTTGATGACAGTCCTTGCTTTCTCATTGACATCTATCTTTGACCCAATTGGTACCTTTATTGGAA
CAGGTCGCGCAACAGGAATCTTTACAGATGAAGATTTGAAAGATATGGAAACAAGTCATGGTTTCTCTTCTAAAATGGAT
AAAGCTTTGTTTGCTGACATGATTGCCACTCCAATCGGAGCAATTTTCGGAACATCAAATACAACTGTTTATGTGGAATC
TGCAGCCGGAATTGGTGCAGGGGGACGTACTGGTCTTGCATCTGTTGTAACGGCAATTATGTTTGCTGTCTCAAGTTTAT
TCTTACCACTTCTTGCAATTGTTCCAACACAAGCAACTGCACCAATCTTGATTATTGTTGGGATGATGATGCTTGGTTCA
TTTAAAGAAATTAAATGGGGTGATTTGACTGAAGCAATTCCTGCTTTCTTTGCCTCAGTATTTATGGGACTTGCTTACTC
AATCTCTTATGGGATTGCAGCTGGTTTCATCACTTACATTCTGGTCAAACTGTTCACAGGAAAAGTGAAAGAAGTAAAAC
CTGTCATTTGGGTTGTTGCACTTTTATTCTTGATTAACTTCGCTGTTTTGGCAGTACTTTAA

Upstream 100 bases:

>100_bases
AATGTTTTTTATTTTATGACGTGTTTGCTTAAAAAGCAAAGACAACTTTTTATCAAAGGGTTGAAATTTTAATCACAGAC
CCTAAAAGGAGAAATTATTC

Downstream 100 bases:

>100_bases
AAAATTAAGATTCGTCAGTAAATGACGGGTCTTTTTTACTCACAGCTTTAGTCGCAAGCCAATGAAACAAATATAATGCA
TATCTAAAGATAAAAAAATT

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MNKFFKLEENGTTVGREIMAGLTTFFAMSYILFVNPQVLGTTGMPVQAVFLATILASIVGTLAIALIANVPYALAPGMGL
NAFFAYTVVLSLGYTWQEALAMVFICGIINIIITFTSIRKAIILGIPESLQHAIGGGIGIFIAYIGIKNAGILRFIADPG
TYVNNHGTITANSSIVPELVTFNNPGVLVALVGIVVTMFFVIRKWRAGILLSILVTTILALLTGVVKVDVNTLFAENNLG
TAINQMGTTFGAAFGPKGFGSLFSDSSRYIEVLMTVLAFSLTSIFDPIGTFIGTGRATGIFTDEDLKDMETSHGFSSKMD
KALFADMIATPIGAIFGTSNTTVYVESAAGIGAGGRTGLASVVTAIMFAVSSLFLPLLAIVPTQATAPILIIVGMMMLGS
FKEIKWGDLTEAIPAFFASVFMGLAYSISYGIAAGFITYILVKLFTGKVKEVKPVIWVVALLFLINFAVLAVL

Sequences:

>Translated_473_residues
MNKFFKLEENGTTVGREIMAGLTTFFAMSYILFVNPQVLGTTGMPVQAVFLATILASIVGTLAIALIANVPYALAPGMGL
NAFFAYTVVLSLGYTWQEALAMVFICGIINIIITFTSIRKAIILGIPESLQHAIGGGIGIFIAYIGIKNAGILRFIADPG
TYVNNHGTITANSSIVPELVTFNNPGVLVALVGIVVTMFFVIRKWRAGILLSILVTTILALLTGVVKVDVNTLFAENNLG
TAINQMGTTFGAAFGPKGFGSLFSDSSRYIEVLMTVLAFSLTSIFDPIGTFIGTGRATGIFTDEDLKDMETSHGFSSKMD
KALFADMIATPIGAIFGTSNTTVYVESAAGIGAGGRTGLASVVTAIMFAVSSLFLPLLAIVPTQATAPILIIVGMMMLGS
FKEIKWGDLTEAIPAFFASVFMGLAYSISYGIAAGFITYILVKLFTGKVKEVKPVIWVVALLFLINFAVLAVL
>Mature_473_residues
MNKFFKLEENGTTVGREIMAGLTTFFAMSYILFVNPQVLGTTGMPVQAVFLATILASIVGTLAIALIANVPYALAPGMGL
NAFFAYTVVLSLGYTWQEALAMVFICGIINIIITFTSIRKAIILGIPESLQHAIGGGIGIFIAYIGIKNAGILRFIADPG
TYVNNHGTITANSSIVPELVTFNNPGVLVALVGIVVTMFFVIRKWRAGILLSILVTTILALLTGVVKVDVNTLFAENNLG
TAINQMGTTFGAAFGPKGFGSLFSDSSRYIEVLMTVLAFSLTSIFDPIGTFIGTGRATGIFTDEDLKDMETSHGFSSKMD
KALFADMIATPIGAIFGTSNTTVYVESAAGIGAGGRTGLASVVTAIMFAVSSLFLPLLAIVPTQATAPILIIVGMMMLGS
FKEIKWGDLTEAIPAFFASVFMGLAYSISYGIAAGFITYILVKLFTGKVKEVKPVIWVVALLFLINFAVLAVL

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine. May work at purine concentrations higher than 100 uM [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=471, Percent_Identity=35.6687898089172, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1790150, Length=466, Percent_Identity=36.9098712446352, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI1790499, Length=453, Percent_Identity=31.7880794701987, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI48994909, Length=458, Percent_Identity=31.2227074235808, Blast_Score=165, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 50077; Mature: 50077

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFFKLEENGTTVGREIMAGLTTFFAMSYILFVNPQVLGTTGMPVQAVFLATILASIVG
CCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHH
TLAIALIANVPYALAPGMGLNAFFAYTVVLSLGYTWQEALAMVFICGIINIIITFTSIRK
HHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AIILGIPESLQHAIGGGIGIFIAYIGIKNAGILRFIADPGTYVNNHGTITANSSIVPELV
HHHHCCCHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCCEECCCCEEEECCCCCCHHH
TFNNPGVLVALVGIVVTMFFVIRKWRAGILLSILVTTILALLTGVVKVDVNTLFAENNLG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCH
TAINQMGTTFGAAFGPKGFGSLFSDSSRYIEVLMTVLAFSLTSIFDPIGTFIGTGRATGI
HHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FTDEDLKDMETSHGFSSKMDKALFADMIATPIGAIFGTSNTTVYVESAAGIGAGGRTGLA
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHH
SVVTAIMFAVSSLFLPLLAIVPTQATAPILIIVGMMMLGSFKEIKWGDLTEAIPAFFASV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
FMGLAYSISYGIAAGFITYILVKLFTGKVKEVKPVIWVVALLFLINFAVLAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNKFFKLEENGTTVGREIMAGLTTFFAMSYILFVNPQVLGTTGMPVQAVFLATILASIVG
CCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHH
TLAIALIANVPYALAPGMGLNAFFAYTVVLSLGYTWQEALAMVFICGIINIIITFTSIRK
HHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AIILGIPESLQHAIGGGIGIFIAYIGIKNAGILRFIADPGTYVNNHGTITANSSIVPELV
HHHHCCCHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCCEECCCCEEEECCCCCCHHH
TFNNPGVLVALVGIVVTMFFVIRKWRAGILLSILVTTILALLTGVVKVDVNTLFAENNLG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCH
TAINQMGTTFGAAFGPKGFGSLFSDSSRYIEVLMTVLAFSLTSIFDPIGTFIGTGRATGI
HHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FTDEDLKDMETSHGFSSKMDKALFADMIATPIGAIFGTSNTTVYVESAAGIGAGGRTGLA
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHH
SVVTAIMFAVSSLFLPLLAIVPTQATAPILIIVGMMMLGSFKEIKWGDLTEAIPAFFASV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
FMGLAYSISYGIAAGFITYILVKLFTGKVKEVKPVIWVVALLFLINFAVLAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 11591660 [H]