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The map label for this gene is dexA

Identifier: 15673663

GI number: 15673663

Start: 1735096

End: 1736721

Strand: Reverse

Name: dexA

Synonym: L128693

Alternate gene names: 15673663

Gene position: 1736721-1735096 (Counterclockwise)

Preceding gene: 15673664

Following gene: 15673662

Centisome position: 73.42

GC content: 36.35

Gene sequence:

>1626_bases
ATGAACTCACATCTTAATGGAGTAGTTAATATGAAAGAAAATTGGTGGCAAAAAACAGTCGTTTATCAGATTTATCCGCG
TTCTTTTATGGATGCTAATGGTGATGGTGTTGGAGATTTGCAAGGAATTATCTCTAAATTAGATTATCTTGAAAAACTTG
GGATTGGTGCAATTTGGTTGAGTCCAGTTTATCAATCGCCAATGGATGATAATGGTTATGATATTTCTGATTATCAAGCA
ATTGCTGATGTTTTTGGAACGATGGCGGATATGGATGAATTGCTCATGGAAGCTAAAAAGCGAAACATTCAAATTGTTAT
GGATTTGGTAGTTAATCATACTTCCGATGAACATAAGTGGTTTGTGGAAGCTAGAAAATCAAAAGATAATGCTTATCGTG
ATTATTATATTTGGGCTGATGAACCCAATGGTTTGCAATCTACCTTTTCTGGTTCTGCTTGGGAATTTGATGAGGAATCG
GGCCAATATTTCCTTCATCTTTTTAGCAAGCGTCAGCCAGATTTAAACTGGGGAAATCCTCAGGTTCATCAAGAAGTTTA
TGACATGATGAATTTCTGGATTGATAAGGGAATCGGCGGTTTTCGCATGGATGTGATTGACTTGATTGGGAAAGAAATTG
ACCAAGAAATCACAGGAAATGGGCCTAAATTACATGAGTATTTGCATGAGATGAATCAGGCAACTTTTGGTCAGAAAAAT
TTGCTGACCGTAGGTGAAACTTGGGGAGCAACACCAGAGATTGCGGAACTTTATTCTGACCCTAAACGTCAAGAATTATC
AATGGTTTTTCAATTTGAACACATCACAAATGCTTATCTTGATGAGGGCGAAAAATGGGATAAAAAGGAATTTTCAGTTT
CAAAACTTAAAGAAATTTTAGCCAAATGGCAAGCTTTAGAAAAAGGTTGGAATTCACTTTTTTGGAATAATCATGATTTA
CCACGGATTGTATCAAATTGGGGAAATGACGGGAAATATCGTTTGAAATCAGCTAAAACTTTTGCGATTTTATTGCATTT
GATGAAAGGAACGCCTTATATTTATCAAGGTGAAGAGCTTGGAATGACGAATTATTCTTTTGAATTAATTGAAGAAGTCA
ATGATATCGAGTCACGGAATATGTTTGCTGAACGCTTAGCTGCTGGTCATTCTGAAAATGAAATCATGGATTCAATTCGT
CGTGTTGGTCGTGATAATGCCAGAACACCGATGCAATGGACGGCTGGAGAAAATGCAGGTTTTACTGATGGAAAACCTTG
GCTCGCTGTCAATCCTAATCATGAAGAAATTAATGCTGATCAAGCCATGAGTGATCCTGATTCTGTTTTTTATACTTATC
AAAAGTTGATTGAACTTCGTAAACAACATGATTGGGTCATTTATGGGGACTTCAAGTTGATTGATTCTGAGGCTGATGTT
TTTGCATATTTGCGGACTTATAAGGGCAAGAAATATTTGGTCGTTGCCAATTTATCTGATGAAGAAAATCAATTTAAAAC
AGGATTTGTCTGTCGTGACTTATTGATTCACAATGAAAATTTCCTGCCTGAACTTTCTCAGATTAAATTAAAAGCTTGGG
AAGCCTTTGCTTGCGAAGTGGAATAG

Upstream 100 bases:

>100_bases
TCTTTGGTTTAGTGAGTATTTTACTGACGGGATTAACTTATAAAGCTGTCAGTAAAATTTTAATTGAGTTCATTCTCCTA
TACCCTAGGAAAATAGGAGA

Downstream 100 bases:

>100_bases
TAAAAGCGCAAAAGGGTGAGGTGAAAATGAGCGAATTTAAAAGAATGGTTGCTGGCGAACTCTATAAAGCAAGTAAAGTT
GAACCAGAATACAAACCTGA

Product: oligo-1,6-glucosidase

Products: NA

Alternate protein names: Dextran glucosidase; Exo-1,6-alpha-glucosidase; Glucodextranase [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MNSHLNGVVNMKENWWQKTVVYQIYPRSFMDANGDGVGDLQGIISKLDYLEKLGIGAIWLSPVYQSPMDDNGYDISDYQA
IADVFGTMADMDELLMEAKKRNIQIVMDLVVNHTSDEHKWFVEARKSKDNAYRDYYIWADEPNGLQSTFSGSAWEFDEES
GQYFLHLFSKRQPDLNWGNPQVHQEVYDMMNFWIDKGIGGFRMDVIDLIGKEIDQEITGNGPKLHEYLHEMNQATFGQKN
LLTVGETWGATPEIAELYSDPKRQELSMVFQFEHITNAYLDEGEKWDKKEFSVSKLKEILAKWQALEKGWNSLFWNNHDL
PRIVSNWGNDGKYRLKSAKTFAILLHLMKGTPYIYQGEELGMTNYSFELIEEVNDIESRNMFAERLAAGHSENEIMDSIR
RVGRDNARTPMQWTAGENAGFTDGKPWLAVNPNHEEINADQAMSDPDSVFYTYQKLIELRKQHDWVIYGDFKLIDSEADV
FAYLRTYKGKKYLVVANLSDEENQFKTGFVCRDLLIHNENFLPELSQIKLKAWEAFACEVE

Sequences:

>Translated_541_residues
MNSHLNGVVNMKENWWQKTVVYQIYPRSFMDANGDGVGDLQGIISKLDYLEKLGIGAIWLSPVYQSPMDDNGYDISDYQA
IADVFGTMADMDELLMEAKKRNIQIVMDLVVNHTSDEHKWFVEARKSKDNAYRDYYIWADEPNGLQSTFSGSAWEFDEES
GQYFLHLFSKRQPDLNWGNPQVHQEVYDMMNFWIDKGIGGFRMDVIDLIGKEIDQEITGNGPKLHEYLHEMNQATFGQKN
LLTVGETWGATPEIAELYSDPKRQELSMVFQFEHITNAYLDEGEKWDKKEFSVSKLKEILAKWQALEKGWNSLFWNNHDL
PRIVSNWGNDGKYRLKSAKTFAILLHLMKGTPYIYQGEELGMTNYSFELIEEVNDIESRNMFAERLAAGHSENEIMDSIR
RVGRDNARTPMQWTAGENAGFTDGKPWLAVNPNHEEINADQAMSDPDSVFYTYQKLIELRKQHDWVIYGDFKLIDSEADV
FAYLRTYKGKKYLVVANLSDEENQFKTGFVCRDLLIHNENFLPELSQIKLKAWEAFACEVE
>Mature_541_residues
MNSHLNGVVNMKENWWQKTVVYQIYPRSFMDANGDGVGDLQGIISKLDYLEKLGIGAIWLSPVYQSPMDDNGYDISDYQA
IADVFGTMADMDELLMEAKKRNIQIVMDLVVNHTSDEHKWFVEARKSKDNAYRDYYIWADEPNGLQSTFSGSAWEFDEES
GQYFLHLFSKRQPDLNWGNPQVHQEVYDMMNFWIDKGIGGFRMDVIDLIGKEIDQEITGNGPKLHEYLHEMNQATFGQKN
LLTVGETWGATPEIAELYSDPKRQELSMVFQFEHITNAYLDEGEKWDKKEFSVSKLKEILAKWQALEKGWNSLFWNNHDL
PRIVSNWGNDGKYRLKSAKTFAILLHLMKGTPYIYQGEELGMTNYSFELIEEVNDIESRNMFAERLAAGHSENEIMDSIR
RVGRDNARTPMQWTAGENAGFTDGKPWLAVNPNHEEINADQAMSDPDSVFYTYQKLIELRKQHDWVIYGDFKLIDSEADV
FAYLRTYKGKKYLVVANLSDEENQFKTGFVCRDLLIHNENFLPELSQIKLKAWEAFACEVE

Specific function: The physiological substrates may be short isomaltosaccharides [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=530, Percent_Identity=28.4905660377358, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI61744479, Length=109, Percent_Identity=33.0275229357798, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI61744483, Length=109, Percent_Identity=33.0275229357798, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI61744477, Length=109, Percent_Identity=33.0275229357798, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI65506891, Length=109, Percent_Identity=33.0275229357798, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI61744481, Length=109, Percent_Identity=33.0275229357798, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI61744475, Length=109, Percent_Identity=33.0275229357798, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1790687, Length=542, Percent_Identity=45.9409594095941, Blast_Score=489, Evalue=1e-139,
Organism=Escherichia coli, GI1786604, Length=187, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25147709, Length=496, Percent_Identity=26.008064516129, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32565753, Length=518, Percent_Identity=22.972972972973, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6322245, Length=537, Percent_Identity=37.9888268156425, Blast_Score=348, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6321726, Length=540, Percent_Identity=36.8518518518519, Blast_Score=346, Evalue=5e-96,
Organism=Saccharomyces cerevisiae, GI6322241, Length=539, Percent_Identity=36.9202226345083, Blast_Score=338, Evalue=1e-93,
Organism=Saccharomyces cerevisiae, GI6322021, Length=539, Percent_Identity=36.9202226345083, Blast_Score=338, Evalue=1e-93,
Organism=Saccharomyces cerevisiae, GI6324416, Length=539, Percent_Identity=36.9202226345083, Blast_Score=337, Evalue=3e-93,
Organism=Saccharomyces cerevisiae, GI6321731, Length=541, Percent_Identity=36.0443622920518, Blast_Score=321, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6319776, Length=541, Percent_Identity=36.0443622920518, Blast_Score=320, Evalue=4e-88,
Organism=Drosophila melanogaster, GI221330053, Length=539, Percent_Identity=34.8794063079777, Blast_Score=299, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24583749, Length=529, Percent_Identity=36.6729678638941, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24583747, Length=529, Percent_Identity=36.6729678638941, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24583745, Length=540, Percent_Identity=33.7037037037037, Blast_Score=278, Evalue=8e-75,
Organism=Drosophila melanogaster, GI24586593, Length=537, Percent_Identity=31.8435754189944, Blast_Score=267, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24586597, Length=535, Percent_Identity=31.7757009345794, Blast_Score=258, Evalue=7e-69,
Organism=Drosophila melanogaster, GI24586599, Length=529, Percent_Identity=31.3799621928166, Blast_Score=258, Evalue=9e-69,
Organism=Drosophila melanogaster, GI24586587, Length=543, Percent_Identity=30.0184162062615, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24586591, Length=500, Percent_Identity=33.2, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI45549022, Length=542, Percent_Identity=31.9188191881919, Blast_Score=244, Evalue=8e-65,
Organism=Drosophila melanogaster, GI24586589, Length=532, Percent_Identity=31.015037593985, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI281360393, Length=484, Percent_Identity=28.099173553719, Blast_Score=189, Evalue=6e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.70 [H]

Molecular weight: Translated: 62683; Mature: 62683

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSHLNGVVNMKENWWQKTVVYQIYPRSFMDANGDGVGDLQGIISKLDYLEKLGIGAIWL
CCCCCCCEEECCHHHHHHEEEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
SPVYQSPMDDNGYDISDYQAIADVFGTMADMDELLMEAKKRNIQIVMDLVVNHTSDEHKW
CHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCCHHH
FVEARKSKDNAYRDYYIWADEPNGLQSTFSGSAWEFDEESGQYFLHLFSKRQPDLNWGNP
HHHHHHCCCCCCEEEEEECCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCH
QVHQEVYDMMNFWIDKGIGGFRMDVIDLIGKEIDQEITGNGPKLHEYLHEMNQATFGQKN
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
LLTVGETWGATPEIAELYSDPKRQELSMVFQFEHITNAYLDEGEKWDKKEFSVSKLKEIL
CEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHH
AKWQALEKGWNSLFWNNHDLPRIVSNWGNDGKYRLKSAKTFAILLHLMKGTPYIYQGEEL
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCEEEECCCC
GMTNYSFELIEEVNDIESRNMFAERLAAGHSENEIMDSIRRVGRDNARTPMQWTAGENAG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEECCCCCCC
FTDGKPWLAVNPNHEEINADQAMSDPDSVFYTYQKLIELRKQHDWVIYGDFKLIDSEADV
CCCCCCEEEECCCHHHCCCHHCCCCCHHHHHHHHHHHHHHHHCCEEEEECEEEECCCHHH
FAYLRTYKGKKYLVVANLSDEENQFKTGFVCRDLLIHNENFLPELSQIKLKAWEAFACEV
HHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEEEEC
E
C
>Mature Secondary Structure
MNSHLNGVVNMKENWWQKTVVYQIYPRSFMDANGDGVGDLQGIISKLDYLEKLGIGAIWL
CCCCCCCEEECCHHHHHHEEEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
SPVYQSPMDDNGYDISDYQAIADVFGTMADMDELLMEAKKRNIQIVMDLVVNHTSDEHKW
CHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCCHHH
FVEARKSKDNAYRDYYIWADEPNGLQSTFSGSAWEFDEESGQYFLHLFSKRQPDLNWGNP
HHHHHHCCCCCCEEEEEECCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCH
QVHQEVYDMMNFWIDKGIGGFRMDVIDLIGKEIDQEITGNGPKLHEYLHEMNQATFGQKN
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
LLTVGETWGATPEIAELYSDPKRQELSMVFQFEHITNAYLDEGEKWDKKEFSVSKLKEIL
CEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHH
AKWQALEKGWNSLFWNNHDLPRIVSNWGNDGKYRLKSAKTFAILLHLMKGTPYIYQGEEL
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCEEEECCCC
GMTNYSFELIEEVNDIESRNMFAERLAAGHSENEIMDSIRRVGRDNARTPMQWTAGENAG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEECCCCCCC
FTDGKPWLAVNPNHEEINADQAMSDPDSVFYTYQKLIELRKQHDWVIYGDFKLIDSEADV
CCCCCCEEEECCCHHHCCCHHCCCCCHHHHHHHHHHHHHHHHCCEEEEECEEEECCCHHH
FAYLRTYKGKKYLVVANLSDEENQFKTGFVCRDLLIHNENFLPELSQIKLKAWEAFACEV
HHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEEEEC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11463916; 8566758; 8021229; 9466257; 9383201 [H]