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The map label for this gene is agl

Identifier: 15673660

GI number: 15673660

Start: 1731220

End: 1732857

Strand: Reverse

Name: agl

Synonym: L128691

Alternate gene names: 15673660

Gene position: 1732857-1731220 (Counterclockwise)

Preceding gene: 15673661

Following gene: 15673659

Centisome position: 73.25

GC content: 35.65

Gene sequence:

>1638_bases
ATGAAAAAAATAAAAACAAATGATTTTCACAAGATGGTAGGTTATCAGATTTATCCAAAATCATTCAAAGATACCAATGG
AGATGGCATTGGCGACATCAATGGCATCATTGAAAAAATTCCTTATCTACGTGAATTGGGGATTGATTTTATCTGGATAA
ATCCAATTTACAAGAGTCCACAAGTTGACGGGGGCTATGATATTTCTGATTATCAAGTCATTGATGAAATGTTTGGCTCA
CTTGAAGATTTTAAAAAATTACTAGATAAAGCGCATGAAAATGGCTTGAAAGTCATCATGGATTTGGTAGTCAATCATAC
ATCAGACCAACACCCTTGGTTTTTAGAAAGTCAAAAATCAAAAGATAATCCTTACCGTGATTATTATTTGTGGGAAGACG
CTAGCCCTAACCAAATGCCAAATGATTGGATTTCCTTTTTTGGTGATTCAACTTGGGCTTATGATGAAAAAACAAAACAA
GCTTATTTTCACGTTTTTGCCAAAGAGCAGCCTGATTTAAATTGGAAAAATCCCAAAGTCCGGCAAGAAATTTATGACAT
GATTCGCTGGTGGTTAGATTTGGGAATAGATGGCTTCAGATTAGATGCGATTTCACACATTCAAAAAATGCCATGGAACT
ATAAAATTAAATCTTGGAAAGGCGACGGCCCGTGGGTGCCTTTCATGAATGTTGCTGGGATTGAAACATATATGTCAGAT
TTGAAAGCTATTTTTGATGAATATGGTGCTTTGACTGTTGGGGAAGCTTCAGGGGTTCGCTCCAAGCAAGCGCCCGATTG
GACCGATGAAGCTGGCTATATCAATATGATTTTTGAATTAGAACATAATGTCAGAAAATCAAATGGCAATGGTCAGGGCA
GTATTTATGGCTACAAAAAAGTCATTATGCGTTGGCAAGAAGATTTGCTTGAACGGGGTTGGAATGCTTTGTATATTGAA
AATCATGACCAACCAAGAAGTATTGATACTTTTGGCGATGGTTCAATAGAATCAGCAAAAGCGTTGGCTGTCAGTTATAT
GCTCTTAAGAGGAACGCCTTTCATATATCAAGGGCAGGAATTTGGGATGACTAATTTTCCATTTACTGACGCAAAGCAAT
TGCGAGCTGACGAGATTAAAAAGAAATATGAAATGTTAATGACAGAACTGTCAGCAAATCAAGCACTAGCAGAAGTCACC
CAAAATAGTCGTGAACACTCAAGAACACCAATGCAGTGGGACAATTCTAAAAATGCAGGATTTACAAGTGGACAAGCTTG
GATGGAAATTAATCCAAATTTTTCTGTTATTAGTAGTCGAACTAATCAAGAACTCATTGAACTTTATAAAAAATTGATTG
AATTACGGCATCAAGAACCAGCGATTTCAGAGGGTTCAATTAAATTTCATTTTAAAAGACATCCTCAAGTTTTAGTTTAT
GAACGAGCTGAATTTTTAATTATTGTCAATTTGGCTGACAAAAAAGCTCATTTAGATTTTACAAAAATTGACAGTTTTAC
TGACAGCTCTGCTGAAAGTTCTGTCATTAATTATCAACAAGTCTTGGGCAGTTCAAATCAAAAATTTCAAGAAAAAATGG
TTCTGTCAGCCTGGGAATATCGGGTTTATAAAAAATAG

Upstream 100 bases:

>100_bases
ATTAACTGATGGAAAATTGACAATTCCAGCTTACAGCACCGTTATTTTAAAAAAATAAATAAGTTCAGTTTAGGGACTTT
AAAAATGAAAATGTAAAACT

Downstream 100 bases:

>100_bases
AAGGTGAGAACAAGATAACACTATGAAACAAATCAAAAGAATTATGGGCATTGACCCTTGGAAAATTACATCAAATCAGA
TTGAAAAAGAAGACCGTCGT

Product: alpha-glucosidase

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MKKIKTNDFHKMVGYQIYPKSFKDTNGDGIGDINGIIEKIPYLRELGIDFIWINPIYKSPQVDGGYDISDYQVIDEMFGS
LEDFKKLLDKAHENGLKVIMDLVVNHTSDQHPWFLESQKSKDNPYRDYYLWEDASPNQMPNDWISFFGDSTWAYDEKTKQ
AYFHVFAKEQPDLNWKNPKVRQEIYDMIRWWLDLGIDGFRLDAISHIQKMPWNYKIKSWKGDGPWVPFMNVAGIETYMSD
LKAIFDEYGALTVGEASGVRSKQAPDWTDEAGYINMIFELEHNVRKSNGNGQGSIYGYKKVIMRWQEDLLERGWNALYIE
NHDQPRSIDTFGDGSIESAKALAVSYMLLRGTPFIYQGQEFGMTNFPFTDAKQLRADEIKKKYEMLMTELSANQALAEVT
QNSREHSRTPMQWDNSKNAGFTSGQAWMEINPNFSVISSRTNQELIELYKKLIELRHQEPAISEGSIKFHFKRHPQVLVY
ERAEFLIIVNLADKKAHLDFTKIDSFTDSSAESSVINYQQVLGSSNQKFQEKMVLSAWEYRVYKK

Sequences:

>Translated_545_residues
MKKIKTNDFHKMVGYQIYPKSFKDTNGDGIGDINGIIEKIPYLRELGIDFIWINPIYKSPQVDGGYDISDYQVIDEMFGS
LEDFKKLLDKAHENGLKVIMDLVVNHTSDQHPWFLESQKSKDNPYRDYYLWEDASPNQMPNDWISFFGDSTWAYDEKTKQ
AYFHVFAKEQPDLNWKNPKVRQEIYDMIRWWLDLGIDGFRLDAISHIQKMPWNYKIKSWKGDGPWVPFMNVAGIETYMSD
LKAIFDEYGALTVGEASGVRSKQAPDWTDEAGYINMIFELEHNVRKSNGNGQGSIYGYKKVIMRWQEDLLERGWNALYIE
NHDQPRSIDTFGDGSIESAKALAVSYMLLRGTPFIYQGQEFGMTNFPFTDAKQLRADEIKKKYEMLMTELSANQALAEVT
QNSREHSRTPMQWDNSKNAGFTSGQAWMEINPNFSVISSRTNQELIELYKKLIELRHQEPAISEGSIKFHFKRHPQVLVY
ERAEFLIIVNLADKKAHLDFTKIDSFTDSSAESSVINYQQVLGSSNQKFQEKMVLSAWEYRVYKK
>Mature_545_residues
MKKIKTNDFHKMVGYQIYPKSFKDTNGDGIGDINGIIEKIPYLRELGIDFIWINPIYKSPQVDGGYDISDYQVIDEMFGS
LEDFKKLLDKAHENGLKVIMDLVVNHTSDQHPWFLESQKSKDNPYRDYYLWEDASPNQMPNDWISFFGDSTWAYDEKTKQ
AYFHVFAKEQPDLNWKNPKVRQEIYDMIRWWLDLGIDGFRLDAISHIQKMPWNYKIKSWKGDGPWVPFMNVAGIETYMSD
LKAIFDEYGALTVGEASGVRSKQAPDWTDEAGYINMIFELEHNVRKSNGNGQGSIYGYKKVIMRWQEDLLERGWNALYIE
NHDQPRSIDTFGDGSIESAKALAVSYMLLRGTPFIYQGQEFGMTNFPFTDAKQLRADEIKKKYEMLMTELSANQALAEVT
QNSREHSRTPMQWDNSKNAGFTSGQAWMEINPNFSVISSRTNQELIELYKKLIELRHQEPAISEGSIKFHFKRHPQVLVY
ERAEFLIIVNLADKKAHLDFTKIDSFTDSSAESSVINYQQVLGSSNQKFQEKMVLSAWEYRVYKK

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=524, Percent_Identity=30.5343511450382, Blast_Score=238, Evalue=7e-63,
Organism=Escherichia coli, GI1790687, Length=499, Percent_Identity=37.875751503006, Blast_Score=347, Evalue=1e-96,
Organism=Escherichia coli, GI1786604, Length=187, Percent_Identity=28.3422459893048, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI32565753, Length=197, Percent_Identity=32.48730964467, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25147709, Length=488, Percent_Identity=24.5901639344262, Blast_Score=99, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6322245, Length=574, Percent_Identity=33.6236933797909, Blast_Score=288, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6321726, Length=462, Percent_Identity=37.4458874458874, Blast_Score=283, Evalue=6e-77,
Organism=Saccharomyces cerevisiae, GI6324416, Length=579, Percent_Identity=32.6424870466321, Blast_Score=276, Evalue=8e-75,
Organism=Saccharomyces cerevisiae, GI6322241, Length=579, Percent_Identity=32.6424870466321, Blast_Score=275, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6322021, Length=579, Percent_Identity=32.6424870466321, Blast_Score=275, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6321731, Length=580, Percent_Identity=33.1034482758621, Blast_Score=268, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6319776, Length=580, Percent_Identity=33.1034482758621, Blast_Score=268, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24583747, Length=550, Percent_Identity=32.3636363636364, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24583749, Length=550, Percent_Identity=32.3636363636364, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24586597, Length=537, Percent_Identity=32.2160148975791, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24586591, Length=568, Percent_Identity=31.3380281690141, Blast_Score=258, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24583745, Length=545, Percent_Identity=31.3761467889908, Blast_Score=254, Evalue=8e-68,
Organism=Drosophila melanogaster, GI24586589, Length=559, Percent_Identity=28.4436493738819, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24586599, Length=535, Percent_Identity=30.2803738317757, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI221330053, Length=507, Percent_Identity=31.3609467455621, Blast_Score=248, Evalue=6e-66,
Organism=Drosophila melanogaster, GI45549022, Length=530, Percent_Identity=29.2452830188679, Blast_Score=241, Evalue=9e-64,
Organism=Drosophila melanogaster, GI24586587, Length=527, Percent_Identity=29.4117647058824, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24586593, Length=200, Percent_Identity=46, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI281360393, Length=153, Percent_Identity=39.8692810457516, Blast_Score=133, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 63398; Mature: 63398

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIKTNDFHKMVGYQIYPKSFKDTNGDGIGDINGIIEKIPYLRELGIDFIWINPIYKSP
CCCCCCCCHHHHHCEEECCCCCCCCCCCCCCHHHHHHHHCCHHHHCCCCEEEECCCCCCC
QVDGGYDISDYQVIDEMFGSLEDFKKLLDKAHENGLKVIMDLVVNHTSDQHPWFLESQKS
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEEECCCC
KDNPYRDYYLWEDASPNQMPNDWISFFGDSTWAYDEKTKQAYFHVFAKEQPDLNWKNPKV
CCCCCCCEEEECCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHEEEEECCCCCCCCCCCHH
RQEIYDMIRWWLDLGIDGFRLDAISHIQKMPWNYKIKSWKGDGPWVPFMNVAGIETYMSD
HHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
LKAIFDEYGALTVGEASGVRSKQAPDWTDEAGYINMIFELEHNVRKSNGNGQGSIYGYKK
HHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHCCCCCCCCCCHHHHH
VIMRWQEDLLERGWNALYIENHDQPRSIDTFGDGSIESAKALAVSYMLLRGTPFIYQGQE
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCC
FGMTNFPFTDAKQLRADEIKKKYEMLMTELSANQALAEVTQNSREHSRTPMQWDNSKNAG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCC
FTSGQAWMEINPNFSVISSRTNQELIELYKKLIELRHQEPAISEGSIKFHFKRHPQVLVY
CCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEE
ERAEFLIIVNLADKKAHLDFTKIDSFTDSSAESSVINYQQVLGSSNQKFQEKMVLSAWEY
ECCCEEEEEEECCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RVYKK
HEECC
>Mature Secondary Structure
MKKIKTNDFHKMVGYQIYPKSFKDTNGDGIGDINGIIEKIPYLRELGIDFIWINPIYKSP
CCCCCCCCHHHHHCEEECCCCCCCCCCCCCCHHHHHHHHCCHHHHCCCCEEEECCCCCCC
QVDGGYDISDYQVIDEMFGSLEDFKKLLDKAHENGLKVIMDLVVNHTSDQHPWFLESQKS
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEEECCCC
KDNPYRDYYLWEDASPNQMPNDWISFFGDSTWAYDEKTKQAYFHVFAKEQPDLNWKNPKV
CCCCCCCEEEECCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHEEEEECCCCCCCCCCCHH
RQEIYDMIRWWLDLGIDGFRLDAISHIQKMPWNYKIKSWKGDGPWVPFMNVAGIETYMSD
HHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
LKAIFDEYGALTVGEASGVRSKQAPDWTDEAGYINMIFELEHNVRKSNGNGQGSIYGYKK
HHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHCCCCCCCCCCHHHHH
VIMRWQEDLLERGWNALYIENHDQPRSIDTFGDGSIESAKALAVSYMLLRGTPFIYQGQE
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCC
FGMTNFPFTDAKQLRADEIKKKYEMLMTELSANQALAEVTQNSREHSRTPMQWDNSKNAG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCC
FTSGQAWMEINPNFSVISSRTNQELIELYKKLIELRHQEPAISEGSIKFHFKRHPQVLVY
CCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEE
ERAEFLIIVNLADKKAHLDFTKIDSFTDSSAESSVINYQQVLGSSNQKFQEKMVLSAWEY
ECCCEEEEEEECCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RVYKK
HEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1761534 [H]