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The map label for this gene is murG

Identifier: 15673571

GI number: 15673571

Start: 1632262

End: 1633335

Strand: Reverse

Name: murG

Synonym: L0238

Alternate gene names: 15673571

Gene position: 1633335-1632262 (Counterclockwise)

Preceding gene: 15673572

Following gene: 15673570

Centisome position: 69.05

GC content: 36.87

Gene sequence:

>1074_bases
ATGCGAATTATCATTACAGGTGGCGGCACAGGCGGTCATATTTATCCAGCGCTAGCTTTCCTTAAGTATTTGGAAAAAGT
AGAACCAGATACAGAAGTGCTTTATATTGGAACGAAAAAAGGCTTGGAGGCAAAAATTGTCCCTCAAGCAGGAATTAAAT
TAAAAACAGTTGATATCCAAGGATTACGTCGTTCACTAAGTCCGCAAAATTTAAAAACAGCTTATAAGTTTTTTAAATCT
GTCTCAGATGCTAAAAAAATTATGAAAGAATTTAAACCGGATGTTGTTTTGGGAACTGGTGGATATGTGGCAGGGCCAGT
TGTTTATGCTGCTGCGCAATTAAAAATTCCAACAATTATACATGAAGGAAATTCTTTCCCAGGAATAACTAATCGTTTTC
TTGCTAAAAAAGTTGACCGAATTGCAGTAGGTTTTCACGCAGCAGAACAATATTTTCCAGCGAGCAAAACGACTTTTACT
GGAAATCCAAGGGCACAAGAAGTTGCAGATGCAGCGGCTCAAGTAGAAAAATTTGAAGAACCAACGGTTGTTATTTTTGG
TGGCTCACGTGGCGCTTTAAAACTTAACAATGCTTTTATTGAAGCCCTTCCTGAATTAGCACAACGTTCATTTAAAACCG
TTTATGCTTCAGGAGAGATTTATTATGATGATTACAAGGAAACTTTTAATCAATATAAAGAAAATTCTAATTTAGATATT
CGTCCTTATATTAATAATATGACAGAACTTTTAGCAAAAAGTCAGCTCTTTTTAGGACGGTCTGGTTCAACAACTATTGC
TGAAGTGACCGCTTTAGGCTTACCAGCCGTTTATGTCCCAAGTCCAAATGTGACAGCTGACCAACAAACTAAAAATGCTC
AAGAATACGTTGACCAAGGTGCAGCTATTATCATCAAAGACGAAGACCTAACGGGTCAAACATTGGTTGAAGCTATTTCA
AATATACTCGAAAATAATGAGAAGTATCAAGAAATGCAAGCAGCTAGTCTAAAAGCGGGCGTTCCAGATGCTAGCCAACG
CCTTTACAATCTAGTGAAAGAAATTAGTAAATAA

Upstream 100 bases:

>100_bases
TCTATCGTTATTTTCTTGTTTATTAGAGAACAGGATTTAATGAAAGTTGGGTACAAAAATATTTGTCAGAGAATCCCCAA
ACTATTGGAGAAAAACAAAC

Downstream 100 bases:

>100_bases
ATGAGTGAAAAAGATAATAACTTAACCCCTTGGCAGCAAAAACATCTTGAATATCAGAAAAGAAAAGCAGAAGAAGCCAA
AAAAGAAAAGAAAGCAAATC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRIIITGGGTGGHIYPALAFLKYLEKVEPDTEVLYIGTKKGLEAKIVPQAGIKLKTVDIQGLRRSLSPQNLKTAYKFFKS
VSDAKKIMKEFKPDVVLGTGGYVAGPVVYAAAQLKIPTIIHEGNSFPGITNRFLAKKVDRIAVGFHAAEQYFPASKTTFT
GNPRAQEVADAAAQVEKFEEPTVVIFGGSRGALKLNNAFIEALPELAQRSFKTVYASGEIYYDDYKETFNQYKENSNLDI
RPYINNMTELLAKSQLFLGRSGSTTIAEVTALGLPAVYVPSPNVTADQQTKNAQEYVDQGAAIIIKDEDLTGQTLVEAIS
NILENNEKYQEMQAASLKAGVPDASQRLYNLVKEISK

Sequences:

>Translated_357_residues
MRIIITGGGTGGHIYPALAFLKYLEKVEPDTEVLYIGTKKGLEAKIVPQAGIKLKTVDIQGLRRSLSPQNLKTAYKFFKS
VSDAKKIMKEFKPDVVLGTGGYVAGPVVYAAAQLKIPTIIHEGNSFPGITNRFLAKKVDRIAVGFHAAEQYFPASKTTFT
GNPRAQEVADAAAQVEKFEEPTVVIFGGSRGALKLNNAFIEALPELAQRSFKTVYASGEIYYDDYKETFNQYKENSNLDI
RPYINNMTELLAKSQLFLGRSGSTTIAEVTALGLPAVYVPSPNVTADQQTKNAQEYVDQGAAIIIKDEDLTGQTLVEAIS
NILENNEKYQEMQAASLKAGVPDASQRLYNLVKEISK
>Mature_357_residues
MRIIITGGGTGGHIYPALAFLKYLEKVEPDTEVLYIGTKKGLEAKIVPQAGIKLKTVDIQGLRRSLSPQNLKTAYKFFKS
VSDAKKIMKEFKPDVVLGTGGYVAGPVVYAAAQLKIPTIIHEGNSFPGITNRFLAKKVDRIAVGFHAAEQYFPASKTTFT
GNPRAQEVADAAAQVEKFEEPTVVIFGGSRGALKLNNAFIEALPELAQRSFKTVYASGEIYYDDYKETFNQYKENSNLDI
RPYINNMTELLAKSQLFLGRSGSTTIAEVTALGLPAVYVPSPNVTADQQTKNAQEYVDQGAAIIIKDEDLTGQTLVEAIS
NILENNEKYQEMQAASLKAGVPDASQRLYNLVKEISK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=365, Percent_Identity=32.0547945205479, Blast_Score=176, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_LACLA (Q9CF92)

Other databases:

- EMBL:   AE005176
- PIR:   E86823
- RefSeq:   NP_267745.1
- ProteinModelPortal:   Q9CF92
- SMR:   Q9CF92
- GeneID:   1115249
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0238
- NMPDR:   fig|272623.1.peg.1631
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   LLAC272623:L0238-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39072; Mature: 39072

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIITGGGTGGHIYPALAFLKYLEKVEPDTEVLYIGTKKGLEAKIVPQAGIKLKTVDIQ
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCCEEEEEEHH
GLRRSLSPQNLKTAYKFFKSVSDAKKIMKEFKPDVVLGTGGYVAGPVVYAAAQLKIPTII
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHEECCEEE
HEGNSFPGITNRFLAKKVDRIAVGFHAAEQYFPASKTTFTGNPRAQEVADAAAQVEKFEE
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHCCC
PTVVIFGGSRGALKLNNAFIEALPELAQRSFKTVYASGEIYYDDYKETFNQYKENSNLDI
CEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHEEEECCCEEECHHHHHHHHHHCCCCCEE
RPYINNMTELLAKSQLFLGRSGSTTIAEVTALGLPAVYVPSPNVTADQQTKNAQEYVDQG
EHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCC
AAIIIKDEDLTGQTLVEAISNILENNEKYQEMQAASLKAGVPDASQRLYNLVKEISK
CEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRIIITGGGTGGHIYPALAFLKYLEKVEPDTEVLYIGTKKGLEAKIVPQAGIKLKTVDIQ
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCCEEEEEEHH
GLRRSLSPQNLKTAYKFFKSVSDAKKIMKEFKPDVVLGTGGYVAGPVVYAAAQLKIPTII
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHEECCEEE
HEGNSFPGITNRFLAKKVDRIAVGFHAAEQYFPASKTTFTGNPRAQEVADAAAQVEKFEE
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHCCC
PTVVIFGGSRGALKLNNAFIEALPELAQRSFKTVYASGEIYYDDYKETFNQYKENSNLDI
CEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHEEEECCCEEECHHHHHHHHHHCCCCCEE
RPYINNMTELLAKSQLFLGRSGSTTIAEVTALGLPAVYVPSPNVTADQQTKNAQEYVDQG
EHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCC
AAIIIKDEDLTGQTLVEAISNILENNEKYQEMQAASLKAGVPDASQRLYNLVKEISK
CEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11337471