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The map label for this gene is yqaG

Identifier: 15673548

GI number: 15673548

Start: 1607814

End: 1608641

Strand: Reverse

Name: yqaG

Synonym: L7563

Alternate gene names: 15673548

Gene position: 1608641-1607814 (Counterclockwise)

Preceding gene: 15673549

Following gene: 15673547

Centisome position: 68.0

GC content: 36.96

Gene sequence:

>828_bases
ATGAAAGACCATTACCGAATTCGCCTTGGAATTTTTGAGCCAGACCAAAAAGCAAAAGCGGTAGTACAATTAGTTCATGG
ATTTGGTGAATACACAAGTCATTATCTCTATTTAATTAATGAATTAGTCAATGCTGGTTTTGTTTGCCTAATGCACGATC
AGAGAGGACATGGTGTTTTGGCAGCTGCTAATCCAAAACTTCAAGGACGAGCTAGAGCTTACGAGAGCCTAATTAGCGAT
GTCTTAGAAGTGAGGAAGATAATTGGTAAAAAGTATCCAAAACTACCGGTTTATCTGTTTGGACATAGTATGGGGGGAAA
TATTTCACTCAATGTTCTTCTAAGAAATATTGAAAATCAAAAACTTTACCAAAAAGCAGTAATTGAATCTCCTTGGCTGG
CGCTGACAAACCCACCAGCCGTCCCGCTTCAAAGACTGGCAGGTTTTTTAGGAAAAATAAGTCCAAAAATTCGAGTTCGA
ACAGGCTTAAAAGTTGAAGCAATTTCTCACCGAAATGATTTAGTAGATTTAGTAACCAAAGATGGAATATATCACGAACT
TCTTTCTTTGCGGCTCTTTTCACAGATTATGGAAGCGGGGCGTTTTGCACAAAGTCAGGCTGGAAATTTGAAAATACCAA
CTTTATTATTCTGTGGTGAATCAGATCAGATTTGTTCGCCCGTAGCCATTCGTTCATTTGCAAACAATGCTGGGAAAAAC
TTAGAATTAATAGAGATTGCAGATGGTTACCATGCTCTCCATTTAGATACAGAGGCAGAGAATTTTATTGAAAGAACTAA
AGATTTTTTTCTAAAAGAAAATTTTTAA

Upstream 100 bases:

>100_bases
TTATAACATTACTAAAGAGAAATAGGATTTGTTATAATGGTTCATAATATGCTAAAAATAGTAAGGAAATCCAATGAAAA
AACAGTATTAAATTATTTCA

Downstream 100 bases:

>100_bases
TTAGTATCAAAGTAAATATAAAAAAAAGAGTCATTCAATTTGAATGGCTCTTTTATTAATTAAACTAAGGAAATTTTTTT
CATTCAAGGAAAAGATAGCT

Product: hypothetical protein

Products: NA

Alternate protein names: Bacilysocin biosynthesis protein ytpA [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKDHYRIRLGIFEPDQKAKAVVQLVHGFGEYTSHYLYLINELVNAGFVCLMHDQRGHGVLAAANPKLQGRARAYESLISD
VLEVRKIIGKKYPKLPVYLFGHSMGGNISLNVLLRNIENQKLYQKAVIESPWLALTNPPAVPLQRLAGFLGKISPKIRVR
TGLKVEAISHRNDLVDLVTKDGIYHELLSLRLFSQIMEAGRFAQSQAGNLKIPTLLFCGESDQICSPVAIRSFANNAGKN
LELIEIADGYHALHLDTEAENFIERTKDFFLKENF

Sequences:

>Translated_275_residues
MKDHYRIRLGIFEPDQKAKAVVQLVHGFGEYTSHYLYLINELVNAGFVCLMHDQRGHGVLAAANPKLQGRARAYESLISD
VLEVRKIIGKKYPKLPVYLFGHSMGGNISLNVLLRNIENQKLYQKAVIESPWLALTNPPAVPLQRLAGFLGKISPKIRVR
TGLKVEAISHRNDLVDLVTKDGIYHELLSLRLFSQIMEAGRFAQSQAGNLKIPTLLFCGESDQICSPVAIRSFANNAGKN
LELIEIADGYHALHLDTEAENFIERTKDFFLKENF
>Mature_275_residues
MKDHYRIRLGIFEPDQKAKAVVQLVHGFGEYTSHYLYLINELVNAGFVCLMHDQRGHGVLAAANPKLQGRARAYESLISD
VLEVRKIIGKKYPKLPVYLFGHSMGGNISLNVLLRNIENQKLYQKAVIESPWLALTNPPAVPLQRLAGFLGKISPKIRVR
TGLKVEAISHRNDLVDLVTKDGIYHELLSLRLFSQIMEAGRFAQSQAGNLKIPTLLFCGESDQICSPVAIRSFANNAGKN
LELIEIADGYHALHLDTEAENFIERTKDFFLKENF

Specific function: Phospholipase involved in the biosynthesis of the antibiotic bacilysocin. It probably catalyzes the hydrolysis of the 2-sn-acyl moiety of phosphatidylglycerol to produce bacilysocin (lysophosphatidylglycerol). Is also able to catalyze the hydrolysis react

COG id: COG2267

COG function: function code I; Lysophospholipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily [H]

Homologues:

Organism=Homo sapiens, GI6005786, Length=252, Percent_Identity=27.3809523809524, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI51242953, Length=252, Percent_Identity=27.3809523809524, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322756, Length=242, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR022742 [H]

Pfam domain/function: PF12146 Hydrolase_4 [H]

EC number: NA

Molecular weight: Translated: 30909; Mature: 30909

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDHYRIRLGIFEPDQKAKAVVQLVHGFGEYTSHYLYLINELVNAGFVCLMHDQRGHGVL
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEE
AAANPKLQGRARAYESLISDVLEVRKIIGKKYPKLPVYLFGHSMGGNISLNVLLRNIENQ
EECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECCCHH
KLYQKAVIESPWLALTNPPAVPLQRLAGFLGKISPKIRVRTGLKVEAISHRNDLVDLVTK
HHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEECCCHHHHHHHHC
DGIYHELLSLRLFSQIMEAGRFAQSQAGNLKIPTLLFCGESDQICSPVAIRSFANNAGKN
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCEEEEECCCCCCCCHHHHHHHHHCCCCC
LELIEIADGYHALHLDTEAENFIERTKDFFLKENF
EEEEEEECCEEEEEECCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKDHYRIRLGIFEPDQKAKAVVQLVHGFGEYTSHYLYLINELVNAGFVCLMHDQRGHGVL
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEE
AAANPKLQGRARAYESLISDVLEVRKIIGKKYPKLPVYLFGHSMGGNISLNVLLRNIENQ
EECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECCCHH
KLYQKAVIESPWLALTNPPAVPLQRLAGFLGKISPKIRVRTGLKVEAISHRNDLVDLVTK
HHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEECCCHHHHHHHHC
DGIYHELLSLRLFSQIMEAGRFAQSQAGNLKIPTLLFCGESDQICSPVAIRSFANNAGKN
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCEEEEECCCCCCCCHHHHHHHHHCCCCC
LELIEIADGYHALHLDTEAENFIERTKDFFLKENF
EEEEEEECCEEEEEECCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]