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The map label for this gene is purQ

Identifier: 15673513

GI number: 15673513

Start: 1576611

End: 1577282

Strand: Reverse

Name: purQ

Synonym: L176360

Alternate gene names: 15673513

Gene position: 1577282-1576611 (Counterclockwise)

Preceding gene: 15673514

Following gene: 15673512

Centisome position: 66.68

GC content: 40.18

Gene sequence:

>672_bases
ATGAAATTTGCAGTCATTCAATTTCCAGGGTCAAATTGTGATTTTGATTTACTTTGGGCAATTCGTGATGTTATGGGAGC
TGAGGCAGAATTTGTCTGGCATGATGAGAAGTCGCTTGCAGGTTTTGACGGAGTGTTGATTCCAGGGGGATTTTCTTATG
GTGATTATTTACGCTGTGGTGCGATTGCGTCATTTGCCAATATTATGCCGGAAATCAAACGTTTGGCTAAAGAAGGGAAA
CCGGTTTTTGGCACTTGCAATGGATTTCAAATTTTGGTTGAATCTGGGCTTTTACCGGGTGTATTGATTCGCAATGAGGG
TTTGAAATTTGTTTCCAAATGGCAAGCTCTTAAAGTTGAAAATAATCAAAGTAATTTTACGACTGAATATGCCAAGGACG
CTTTGATTAATTTACCAATTGCTCACGGTGAGGGTCAATATGTTGCTGACGAAGCTCAGCTTGCTGAACTTAAAGCAAAT
GGGCAAATTATTTTCACTTATGCTGACGAAAATCCTAATGGGTCAGTTGAAAATATTGCTGGAATTGTCAATAAAGAAGG
AAATGTGCTTGGGATGATGCCTCACCCTGAGCGGGCCATGGAAGAACTGCTTGGTGGCGCTGATGGAGTAGATTTGTTTG
CTTCTGTCTTGAAAAACTTTGTTGGAAAATAA

Upstream 100 bases:

>100_bases
GCGCAAAAGCAATTGAAATTGCCAATGAATTGTTGGCAAATCCAAATATGGAAACTTATAAAGTTGAAATTTTGAATGAA
CAAAGCGAAGGAGCTAATTA

Downstream 100 bases:

>100_bases
AAAAATTACTGACAGAATTTAGATTTTAAAAAACGAATCTGTCAGTAAATTTGTAATTTGAAATAATTGAATTCAGAGCG
CTGAAAGCTTTTAAAGTAGA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKFAVIQFPGSNCDFDLLWAIRDVMGAEAEFVWHDEKSLAGFDGVLIPGGFSYGDYLRCGAIASFANIMPEIKRLAKEGK
PVFGTCNGFQILVESGLLPGVLIRNEGLKFVSKWQALKVENNQSNFTTEYAKDALINLPIAHGEGQYVADEAQLAELKAN
GQIIFTYADENPNGSVENIAGIVNKEGNVLGMMPHPERAMEELLGGADGVDLFASVLKNFVGK

Sequences:

>Translated_223_residues
MKFAVIQFPGSNCDFDLLWAIRDVMGAEAEFVWHDEKSLAGFDGVLIPGGFSYGDYLRCGAIASFANIMPEIKRLAKEGK
PVFGTCNGFQILVESGLLPGVLIRNEGLKFVSKWQALKVENNQSNFTTEYAKDALINLPIAHGEGQYVADEAQLAELKAN
GQIIFTYADENPNGSVENIAGIVNKEGNVLGMMPHPERAMEELLGGADGVDLFASVLKNFVGK
>Mature_223_residues
MKFAVIQFPGSNCDFDLLWAIRDVMGAEAEFVWHDEKSLAGFDGVLIPGGFSYGDYLRCGAIASFANIMPEIKRLAKEGK
PVFGTCNGFQILVESGLLPGVLIRNEGLKFVSKWQALKVENNQSNFTTEYAKDALINLPIAHGEGQYVADEAQLAELKAN
GQIIFTYADENPNGSVENIAGIVNKEGNVLGMMPHPERAMEELLGGADGVDLFASVLKNFVGK

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=240, Percent_Identity=27.5, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI48994899, Length=226, Percent_Identity=28.3185840707965, Blast_Score=72, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321498, Length=231, Percent_Identity=26.8398268398268, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582111, Length=237, Percent_Identity=29.535864978903, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24582109, Length=237, Percent_Identity=29.535864978903, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI17137292, Length=237, Percent_Identity=29.535864978903, Blast_Score=91, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24206; Mature: 24206

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAVIQFPGSNCDFDLLWAIRDVMGAEAEFVWHDEKSLAGFDGVLIPGGFSYGDYLRCG
CCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCCCHHHHHH
AIASFANIMPEIKRLAKEGKPVFGTCNGFQILVESGLLPGVLIRNEGLKFVSKWQALKVE
HHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCEEEECCCCHHHHHHEEEEEE
NNQSNFTTEYAKDALINLPIAHGEGQYVADEAQLAELKANGQIIFTYADENPNGSVENIA
CCCCCCHHHHHHHHEEECEEECCCCCEEECHHHHHHHCCCCEEEEEECCCCCCCCHHHHH
GIVNKEGNVLGMMPHPERAMEELLGGADGVDLFASVLKNFVGK
HHCCCCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFAVIQFPGSNCDFDLLWAIRDVMGAEAEFVWHDEKSLAGFDGVLIPGGFSYGDYLRCG
CCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCCCHHHHHH
AIASFANIMPEIKRLAKEGKPVFGTCNGFQILVESGLLPGVLIRNEGLKFVSKWQALKVE
HHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCEEEECCCCHHHHHHEEEEEE
NNQSNFTTEYAKDALINLPIAHGEGQYVADEAQLAELKANGQIIFTYADENPNGSVENIA
CCCCCCHHHHHHHHEEECEEECCCCCEEECHHHHHHHCCCCEEEEEECCCCCCCCHHHHH
GIVNKEGNVLGMMPHPERAMEELLGGADGVDLFASVLKNFVGK
HHCCCCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10071207 [H]