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The map label for this gene is ptbA

Identifier: 15673442

GI number: 15673442

Start: 1490930

End: 1492840

Strand: Reverse

Name: ptbA

Synonym: L90678

Alternate gene names: 15673442

Gene position: 1492840-1490930 (Counterclockwise)

Preceding gene: 15673443

Following gene: 15673441

Centisome position: 63.11

GC content: 38.15

Gene sequence:

>1911_bases
ATGGGCAAATATGAAGCTCTTGCAAAAGACATTGTAGCAAATGTAGGTGGCAAAGAAAATGTCATCTCAGTGATTAACTG
TATTACACGGTTACGTTTTAAACTCAGAGATGAGAAAAAAGCAAATACCGATGTCCTGAAAAATATGGATGGTGTAGTTA
CAGTAATGCAATCTGGCGGCCAATACCAAGTCGTTATTGGGAATCATGTACCAGAAGTGCGTGCAGATGTAGATGCTGTC
CTTGGGGTACTTGATACCTCACCAGCAGACTCTACACAAAAAGGAAACCTTTTCGATCAATTTGTGGAATTGATCTCAGG
AATTTTCCAACCAATATTAGCTCCATTAGCAGCAGCGGGTATGATTAAAGGGGTTAATGCAATTTTATCCTTTGCCTTGG
GACAAAGTTTTCAAGCGTCTGCAACCTATGCTGTTTTTAATGCAATGGGTGATGGTCTATTTCTCTTCCTACCAATTTTC
ATTGGATATACTTCAATGAAAAAATTTAATGGTTCACCATTTGTTGGAATGATGATTGCCGCAGCACTTGTTTACCCAGG
TTTCGTAGACGGAACAGTTGCAAAAACATTTGCAGAAAGTGGCGGATTAAGCCTCTTTGGAATTCCTTTTTCAGTACCAA
CTGCTGGCTACGGGTCTTCTGTAATGCCAATTATTGCCATTACAGCATTTGCAGCATTTTTAGAACACCAGTTAAAGAAA
ATTATTCCTGATGTAGTAAAGCTTTTCTTGACACCATTCTTTACGGCAATCATCTCAATTCCTCTAGGCTTCCTAGTTAT
TGGACCAGTAATGAATCTTGCTTCAGATGCTTTAGGCAAAGGTTTACTAGCATTACAAGGATTTAATCCTATTATCTTTG
GTTTAGTGCTAGGATTTGCTTGGCAAGTCTTAGTCATGTTTGGACTACATTGGGCAATTGTTCCATTTGCAATTATCGCA
TTAGCAAAAGGAGAACCAACCGCGCTTTTAATTGCCGCAAGTGTTGCATCGTTTGCGCAAACTGGAGCTGTTGGAGCAGT
GATGCTAAAAACAAAAGATAAACGACTTCGTGAATTAGCAATACCAGCCTTTATTTCTGGTTGGTTTGGTGTTACAGAAC
CAGCAATTTACGGAATTACCCTCCCTAAGAAACGTCCATTTTGGGTTTCATGTATCGTAAGTGGAATTTTATCAGCTGTT
GCCATGGCCTTGGGAATTAAAGCCTACACAATGGGAGCTTTGGGAATCTTCAGTTTTACATCTAATATTACCCTTACAGG
TGAAGTTTCAGGCGCGATTAAAATTATGATTGTATCAGCTGTAGCAGTTATAGCAGGCTTTGTAGTAACCTATCTTGTGG
GATTTGAAGATGATGTTATTGAAAATCCAATCCCTGACAAAAAATTTAATAAACAAAAAACGAATAAAGAAATAATTGGA
AGCCCTCTTGAAGGAAAAGTTATTCCACTATCACAAGTTAAAGATGCAGCCTTTTCTGCAGGTGTAATGGGCAAAGGAGC
AGCGATTGAACCAACACTAGGTGAGGTTCGTGCTCCATTTGATGGAATGGTTATGATTTTGTTCCCAACTAAACATGCAG
TAGGTTTAATTTCAAATGAGGGAACTGAACTTCTCATTCATATCGGAATAGATACTGTCCAACTTGAAGGAAAATACTTT
GAAACCTTTGTAAAACAAGGACAGAGTGTAAAAAAAGGTGACTTACTCCTCAAGTTTGATATTGAGCGTATTCAAAATGC
GGGATACAGTACTCAAGTTCCAATCATTGTAACAAATACTCAGGATTATATGGACATTTTAGTTACAAATCAATCGACGA
TTCATCAAAATGAAGTGTTACTAACTGCAGTTAATGCACAAACAACTGAATTAGTGGCAAATCCAGTTTAA

Upstream 100 bases:

>100_bases
TTTTTAAGATGACTTTAGTCATCATCAACTATGGTAACAATTGGATCGTGACATTAAGTTGGCGAAACCTCTAAAAAATA
TATTATTTTGGAGGTTTGTA

Downstream 100 bases:

>100_bases
AATAGCATTGATGAAAAACTTTAAAAATTAGATAGGAAAATTATAAAATGACATTTAAAACAGACTTTTTATGGGGTGGA
GCAACGGCAGCAAATCAATT

Product: beta-glucoside-specific PTS system IIABC component

Products: NA

Alternate protein names: EIIBCA-Bgl; EII-Bgl; Beta-glucoside-specific phosphotransferase enzyme IIB component; PTS system beta-glucoside-specific EIIB component; Beta-glucoside permease IIC component; PTS system beta-glucoside-specific EIIC component; Beta-glucoside-specific phosphotransferase enzyme IIA component; PTS system beta-glucoside-specific EIIA component [H]

Number of amino acids: Translated: 636; Mature: 635

Protein sequence:

>636_residues
MGKYEALAKDIVANVGGKENVISVINCITRLRFKLRDEKKANTDVLKNMDGVVTVMQSGGQYQVVIGNHVPEVRADVDAV
LGVLDTSPADSTQKGNLFDQFVELISGIFQPILAPLAAAGMIKGVNAILSFALGQSFQASATYAVFNAMGDGLFLFLPIF
IGYTSMKKFNGSPFVGMMIAAALVYPGFVDGTVAKTFAESGGLSLFGIPFSVPTAGYGSSVMPIIAITAFAAFLEHQLKK
IIPDVVKLFLTPFFTAIISIPLGFLVIGPVMNLASDALGKGLLALQGFNPIIFGLVLGFAWQVLVMFGLHWAIVPFAIIA
LAKGEPTALLIAASVASFAQTGAVGAVMLKTKDKRLRELAIPAFISGWFGVTEPAIYGITLPKKRPFWVSCIVSGILSAV
AMALGIKAYTMGALGIFSFTSNITLTGEVSGAIKIMIVSAVAVIAGFVVTYLVGFEDDVIENPIPDKKFNKQKTNKEIIG
SPLEGKVIPLSQVKDAAFSAGVMGKGAAIEPTLGEVRAPFDGMVMILFPTKHAVGLISNEGTELLIHIGIDTVQLEGKYF
ETFVKQGQSVKKGDLLLKFDIERIQNAGYSTQVPIIVTNTQDYMDILVTNQSTIHQNEVLLTAVNAQTTELVANPV

Sequences:

>Translated_636_residues
MGKYEALAKDIVANVGGKENVISVINCITRLRFKLRDEKKANTDVLKNMDGVVTVMQSGGQYQVVIGNHVPEVRADVDAV
LGVLDTSPADSTQKGNLFDQFVELISGIFQPILAPLAAAGMIKGVNAILSFALGQSFQASATYAVFNAMGDGLFLFLPIF
IGYTSMKKFNGSPFVGMMIAAALVYPGFVDGTVAKTFAESGGLSLFGIPFSVPTAGYGSSVMPIIAITAFAAFLEHQLKK
IIPDVVKLFLTPFFTAIISIPLGFLVIGPVMNLASDALGKGLLALQGFNPIIFGLVLGFAWQVLVMFGLHWAIVPFAIIA
LAKGEPTALLIAASVASFAQTGAVGAVMLKTKDKRLRELAIPAFISGWFGVTEPAIYGITLPKKRPFWVSCIVSGILSAV
AMALGIKAYTMGALGIFSFTSNITLTGEVSGAIKIMIVSAVAVIAGFVVTYLVGFEDDVIENPIPDKKFNKQKTNKEIIG
SPLEGKVIPLSQVKDAAFSAGVMGKGAAIEPTLGEVRAPFDGMVMILFPTKHAVGLISNEGTELLIHIGIDTVQLEGKYF
ETFVKQGQSVKKGDLLLKFDIERIQNAGYSTQVPIIVTNTQDYMDILVTNQSTIHQNEVLLTAVNAQTTELVANPV
>Mature_635_residues
GKYEALAKDIVANVGGKENVISVINCITRLRFKLRDEKKANTDVLKNMDGVVTVMQSGGQYQVVIGNHVPEVRADVDAVL
GVLDTSPADSTQKGNLFDQFVELISGIFQPILAPLAAAGMIKGVNAILSFALGQSFQASATYAVFNAMGDGLFLFLPIFI
GYTSMKKFNGSPFVGMMIAAALVYPGFVDGTVAKTFAESGGLSLFGIPFSVPTAGYGSSVMPIIAITAFAAFLEHQLKKI
IPDVVKLFLTPFFTAIISIPLGFLVIGPVMNLASDALGKGLLALQGFNPIIFGLVLGFAWQVLVMFGLHWAIVPFAIIAL
AKGEPTALLIAASVASFAQTGAVGAVMLKTKDKRLRELAIPAFISGWFGVTEPAIYGITLPKKRPFWVSCIVSGILSAVA
MALGIKAYTMGALGIFSFTSNITLTGEVSGAIKIMIVSAVAVIAGFVVTYLVGFEDDVIENPIPDKKFNKQKTNKEIIGS
PLEGKVIPLSQVKDAAFSAGVMGKGAAIEPTLGEVRAPFDGMVMILFPTKHAVGLISNEGTELLIHIGIDTVQLEGKYFE
TFVKQGQSVKKGDLLLKFDIERIQNAGYSTQVPIIVTNTQDYMDILVTNQSTIHQNEVLLTAVNAQTTELVANPV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790159, Length=632, Percent_Identity=38.9240506329114, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI48994906, Length=467, Percent_Identity=29.9785867237687, Blast_Score=196, Evalue=5e-51,
Organism=Escherichia coli, GI2367362, Length=419, Percent_Identity=29.3556085918854, Blast_Score=158, Evalue=1e-39,
Organism=Escherichia coli, GI1788769, Length=479, Percent_Identity=27.348643006263, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1788757, Length=138, Percent_Identity=34.7826086956522, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786894, Length=134, Percent_Identity=35.8208955223881, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011297 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 67631; Mature: 67500

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1 ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKYEALAKDIVANVGGKENVISVINCITRLRFKLRDEKKANTDVLKNMDGVVTVMQSGG
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHEECCC
QYQVVIGNHVPEVRADVDAVLGVLDTSPADSTQKGNLFDQFVELISGIFQPILAPLAAAG
EEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MIKGVNAILSFALGQSFQASATYAVFNAMGDGLFLFLPIFIGYTSMKKFNGSPFVGMMIA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AALVYPGFVDGTVAKTFAESGGLSLFGIPFSVPTAGYGSSVMPIIAITAFAAFLEHQLKK
HHHHCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IIPDVVKLFLTPFFTAIISIPLGFLVIGPVMNLASDALGKGLLALQGFNPIIFGLVLGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHH
WQVLVMFGLHWAIVPFAIIALAKGEPTALLIAASVASFAQTGAVGAVMLKTKDKRLRELA
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCCCCEEEEEECCHHHHHHHH
IPAFISGWFGVTEPAIYGITLPKKRPFWVSCIVSGILSAVAMALGIKAYTMGALGIFSFT
HHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
SNITLTGEVSGAIKIMIVSAVAVIAGFVVTYLVGFEDDVIENPIPDKKFNKQKTNKEIIG
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHCCHHHCC
SPLEGKVIPLSQVKDAAFSAGVMGKGAAIEPTLGEVRAPFDGMVMILFPTKHAVGLISNE
CCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCEEEEEEECCCCEEEECCC
GTELLIHIGIDTVQLEGKYFETFVKQGQSVKKGDLLLKFDIERIQNAGYSTQVPIIVTNT
CCEEEEEECCEEEEECCHHHHHHHHCCCCCCCCCEEEEEEHHHHHCCCCCEECCEEEECC
QDYMDILVTNQSTIHQNEVLLTAVNAQTTELVANPV
CCCEEEEEECCCCCCCCCEEEEEECCCHHHHHCCCC
>Mature Secondary Structure 
GKYEALAKDIVANVGGKENVISVINCITRLRFKLRDEKKANTDVLKNMDGVVTVMQSGG
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHEECCC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CCCEEEEEECCCCCCCCCEEEEEECCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]