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The map label for this gene is bglH

Identifier: 15673441

GI number: 15673441

Start: 1489446

End: 1490882

Strand: Reverse

Name: bglH

Synonym: L89194

Alternate gene names: 15673441

Gene position: 1490882-1489446 (Counterclockwise)

Preceding gene: 15673442

Following gene: 15673440

Centisome position: 63.02

GC content: 35.63

Gene sequence:

>1437_bases
ATGACATTTAAAACAGACTTTTTATGGGGTGGAGCAACGGCAGCAAATCAATTAGAAGGTGCTTATGATATAGATGGTAA
AGGGCTCTCAGTAGCAGATGCAATGCCAGGAGGTAAAGAAAGATTGGCAATTCTTGCAAGTCCTGAATTTGATTGGACGA
TTGATATTGAACATTTTACTTATCCAAATCATGATGGAATTGATCATTATCATCATTTTAAAGAAGACATTGCATTATTT
GCAGAAATGGGATTTAAAGCTTACCGTTTTTCGGTAGCTTGGTCAAGAATTTTTCCAATGGGAGATGAAACAACTCCAAA
TGAAAAAGGTTTGCTTTTTTATGATCAGCTAATTGATGAGTGTTTGAAATATGGAATTGAACCAGTGGTTACAATTTCCC
ACTATGAAATGCCACTTAATTTAGCTAAAACATATGGAGGATGGAAAAATCGCGAACTAATCGAATTTTATGTCCGTTTT
GCAAAAGTTTTGTTAGAACGTTATCAAGACAAAGTGAAATATTGGATGACTTTTAACGAAATCAATTCAGCAACATTCTT
TTCAGGTTTAAGTCAAGGACTTGTTCCATCTAATGGTGGAGATGACAAAACTAATGTTTTCAAAGCTTGGCATAATCAAT
TTGTTGCAAGTGCTCAAGCTGTAAAATTTGGGCATGACTTGAATAAGAGTTTACAAATTGGTTGTATGAGTATTTATTCA
ACAACTTATTCGTTCGATGCAAACCCAGTAAATCAATTAGCAACACAAGAAAGCATTCAAGAGTTTAATTATTTCTGTAA
TGATGTACAAGTTCGAGGAGCCTATCCCGCATTTACGAATCGACTTCACCGTAAACACGGAGTAAATGCAGATGCACTTG
AAATTTCCGAAGAAGATCTAAAGATAATAAAAGAAGGAACAGTTGATTATATAGGATTTAGTTATTATATGTCGACTGTA
GAATCAAAAACAGGGGAAGGCGTTCAAGCTTCAGGAAATATGGTTCTTGGAGGAGTTAAAAACCCCTTCTTAAAAGAAAG
CGAATGGGGTTGGGCAGTTGACCCTGACGGACTTTGTTATGCCCTTAATGATTTATACGGTCGCTATCAAGTTCCGCTCT
TCATTGTCGAAAATGGCTTAGGCGCAATTGATAAAGTACAAGAAGACGGAACGATACAAGATGATTATCGTATTGATTAT
CTCAAAAAACACATTCAATCAATGAATGAAGCAGTTGAAGACGGCGTTGACCTAATGGGTTACACGCCTTGGGGATGTAT
TGATTTAGTTTCAGCATCTACAGGAGAAATGAGTAAGCGTTATGGATTCATCTACGTTGACTTAGATGACGAAGGAAAAG
GAACAAAAAAACGTTCTAAGAAAAAATCATTTGATTGGTATAAAGAAGTAATAGCTTCAAATGCTACCAACTTGTAA

Upstream 100 bases:

>100_bases
TACTAACTGCAGTTAATGCACAAACAACTGAATTAGTGGCAAATCCAGTTTAAAATAGCATTGATGAAAAACTTTAAAAA
TTAGATAGGAAAATTATAAA

Downstream 100 bases:

>100_bases
AAAAATCCTCATCTTTTTGATGAGGATTTTTTCTATTTTGCATTTAAATATAAAAGAGCTATTTGAATAGTTCTTTTTTG
TTTGACTTAAGTAAAAAACA

Product: beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MTFKTDFLWGGATAANQLEGAYDIDGKGLSVADAMPGGKERLAILASPEFDWTIDIEHFTYPNHDGIDHYHHFKEDIALF
AEMGFKAYRFSVAWSRIFPMGDETTPNEKGLLFYDQLIDECLKYGIEPVVTISHYEMPLNLAKTYGGWKNRELIEFYVRF
AKVLLERYQDKVKYWMTFNEINSATFFSGLSQGLVPSNGGDDKTNVFKAWHNQFVASAQAVKFGHDLNKSLQIGCMSIYS
TTYSFDANPVNQLATQESIQEFNYFCNDVQVRGAYPAFTNRLHRKHGVNADALEISEEDLKIIKEGTVDYIGFSYYMSTV
ESKTGEGVQASGNMVLGGVKNPFLKESEWGWAVDPDGLCYALNDLYGRYQVPLFIVENGLGAIDKVQEDGTIQDDYRIDY
LKKHIQSMNEAVEDGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGKGTKKRSKKKSFDWYKEVIASNATNL

Sequences:

>Translated_478_residues
MTFKTDFLWGGATAANQLEGAYDIDGKGLSVADAMPGGKERLAILASPEFDWTIDIEHFTYPNHDGIDHYHHFKEDIALF
AEMGFKAYRFSVAWSRIFPMGDETTPNEKGLLFYDQLIDECLKYGIEPVVTISHYEMPLNLAKTYGGWKNRELIEFYVRF
AKVLLERYQDKVKYWMTFNEINSATFFSGLSQGLVPSNGGDDKTNVFKAWHNQFVASAQAVKFGHDLNKSLQIGCMSIYS
TTYSFDANPVNQLATQESIQEFNYFCNDVQVRGAYPAFTNRLHRKHGVNADALEISEEDLKIIKEGTVDYIGFSYYMSTV
ESKTGEGVQASGNMVLGGVKNPFLKESEWGWAVDPDGLCYALNDLYGRYQVPLFIVENGLGAIDKVQEDGTIQDDYRIDY
LKKHIQSMNEAVEDGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGKGTKKRSKKKSFDWYKEVIASNATNL
>Mature_477_residues
TFKTDFLWGGATAANQLEGAYDIDGKGLSVADAMPGGKERLAILASPEFDWTIDIEHFTYPNHDGIDHYHHFKEDIALFA
EMGFKAYRFSVAWSRIFPMGDETTPNEKGLLFYDQLIDECLKYGIEPVVTISHYEMPLNLAKTYGGWKNRELIEFYVRFA
KVLLERYQDKVKYWMTFNEINSATFFSGLSQGLVPSNGGDDKTNVFKAWHNQFVASAQAVKFGHDLNKSLQIGCMSIYST
TYSFDANPVNQLATQESIQEFNYFCNDVQVRGAYPAFTNRLHRKHGVNADALEISEEDLKIIKEGTVDYIGFSYYMSTVE
SKTGEGVQASGNMVLGGVKNPFLKESEWGWAVDPDGLCYALNDLYGRYQVPLFIVENGLGAIDKVQEDGTIQDDYRIDYL
KKHIQSMNEAVEDGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGKGTKKRSKKKSFDWYKEVIASNATNL

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=492, Percent_Identity=30.6910569105691, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI13273313, Length=495, Percent_Identity=28.6868686868687, Blast_Score=182, Evalue=9e-46,
Organism=Homo sapiens, GI110681710, Length=494, Percent_Identity=29.3522267206478, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI28376633, Length=499, Percent_Identity=25.8517034068136, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI24497614, Length=488, Percent_Identity=27.0491803278689, Blast_Score=143, Evalue=3e-34,
Organism=Escherichia coli, GI2367174, Length=485, Percent_Identity=52.1649484536083, Blast_Score=508, Evalue=1e-145,
Organism=Escherichia coli, GI1789070, Length=477, Percent_Identity=49.0566037735849, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI2367270, Length=481, Percent_Identity=49.8960498960499, Blast_Score=452, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17552856, Length=494, Percent_Identity=31.1740890688259, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17539390, Length=491, Percent_Identity=28.3095723014257, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21356577, Length=500, Percent_Identity=28.2, Blast_Score=163, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54039; Mature: 53908

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFKTDFLWGGATAANQLEGAYDIDGKGLSVADAMPGGKERLAILASPEFDWTIDIEHFT
CCEECCEEECCCCHHHHCCCCEECCCCCCCHHCCCCCCCCEEEEEECCCCCEEEEEEEEE
YPNHDGIDHYHHFKEDIALFAEMGFKAYRFSVAWSRIFPMGDETTPNEKGLLFYDQLIDE
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEHHHEECCCCCCCCCCCCEEHHHHHHHH
CLKYGIEPVVTISHYEMPLNLAKTYGGWKNRELIEFYVRFAKVLLERYQDKVKYWMTFNE
HHHCCCCEEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEHHH
INSATFFSGLSQGLVPSNGGDDKTNVFKAWHNQFVASAQAVKFGHDLNKSLQIGCMSIYS
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEHH
TTYSFDANPVNQLATQESIQEFNYFCNDVQVRGAYPAFTNRLHRKHGVNADALEISEEDL
EEEECCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCEECCHHHH
KIIKEGTVDYIGFSYYMSTVESKTGEGVQASGNMVLGGVKNPFLKESEWGWAVDPDGLCY
HHHHCCCHHHHHHHHHHHHHHHCCCCCEECCCCEEECCCCCCCCCCCCCCCCCCCCCCEE
ALNDLYGRYQVPLFIVENGLGAIDKVQEDGTIQDDYRIDYLKKHIQSMNEAVEDGVDLMG
EEHHHCCCEECEEEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
YTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGKGTKKRSKKKSFDWYKEVIASNATNL
CCCCCHHHHHCCCCCCHHHCCEEEEEEECCCCCCCHHHHHHCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TFKTDFLWGGATAANQLEGAYDIDGKGLSVADAMPGGKERLAILASPEFDWTIDIEHFT
CEECCEEECCCCHHHHCCCCEECCCCCCCHHCCCCCCCCEEEEEECCCCCEEEEEEEEE
YPNHDGIDHYHHFKEDIALFAEMGFKAYRFSVAWSRIFPMGDETTPNEKGLLFYDQLIDE
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEHHHEECCCCCCCCCCCCEEHHHHHHHH
CLKYGIEPVVTISHYEMPLNLAKTYGGWKNRELIEFYVRFAKVLLERYQDKVKYWMTFNE
HHHCCCCEEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEHHH
INSATFFSGLSQGLVPSNGGDDKTNVFKAWHNQFVASAQAVKFGHDLNKSLQIGCMSIYS
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEHH
TTYSFDANPVNQLATQESIQEFNYFCNDVQVRGAYPAFTNRLHRKHGVNADALEISEEDL
EEEECCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCEECCHHHH
KIIKEGTVDYIGFSYYMSTVESKTGEGVQASGNMVLGGVKNPFLKESEWGWAVDPDGLCY
HHHHCCCHHHHHHHHHHHHHHHCCCCCEECCCCEEECCCCCCCCCCCCCCCCCCCCCCEE
ALNDLYGRYQVPLFIVENGLGAIDKVQEDGTIQDDYRIDYLKKHIQSMNEAVEDGVDLMG
EEHHHCCCEECEEEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
YTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGKGTKKRSKKKSFDWYKEVIASNATNL
CCCCCHHHHHCCCCCCHHHCCEEEEEEECCCCCCCHHHHHHCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377 [H]