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The map label for this gene is pyrZ

Identifier: 15673329

GI number: 15673329

Start: 1383817

End: 1384605

Strand: Reverse

Name: pyrZ

Synonym: L183563

Alternate gene names: 15673329

Gene position: 1384605-1383817 (Counterclockwise)

Preceding gene: 15673330

Following gene: 15673328

Centisome position: 58.53

GC content: 38.53

Gene sequence:

>789_bases
ATGCCTAAGTTACAAGAGATGATGACGATTGTCAGCCAACGTGAGGTTGCTTCTAATATTTTCGAGATGGTTCTTAAAGG
AGAGCTAGTAGAAGAGATGGATTTGCCGGGACAATTTTTACATCTTGCTGTGCCTAATGCTAGTATGCTTTTACGTCGCC
CAATCTCTATTTCCAGTTGGGATAAAGTCGCAAAAACTTGTACGATTCTTTATCGAATTGGGGACGAAACAAGTGGAACT
TATGAAATTTCAAAATTACAATCAGGTGCAAAAATTGATGTAATGGGCCCACTGGGAAATGGTTTTCCAGTAGATGAAGT
AGTTTCGACTGATAAAATTTTAATTGTCGGCGGAGGAATTGGGGTTCCACCTCTCTATGAATTGGCCAAACAACTTGAAG
AAAAAAACTGCCAAATGACCATTTTGCTAGGTTTTGCTTCTGAAAAGGTCAAGATTTTAGAGAAGGAATTTGCTGAATTA
AAAAATGTAAGCTTGAAAATTGCAACTGACGATGGCTCTTATGGAACAAAAGGTCATGTTGGGATGTTGATGGAAGAAAT
TGATTTTGAAGTTGACGCTCTTTATACTTGTGGTGCGCCAGCCATGCTCAAAGCTGTTGCAAAAAAATATGAACAGTTGG
AACGACTTTATATTTCAATGGAAAGCCGGATGGCTTGTGGAATCGGAGCATGTTATGCTTGCGTTGAACATGATAAAGAA
GATGAGAATCATGCCCTTAAAGTCTGTGAAGATGGCCCTGTATTTTTAGGAAAACAGCTATTACTATAA

Upstream 100 bases:

>100_bases
AACTTTCTGTCAGTAATGCGATTAACATGAGCATTTTATCAATGAATAAAAGAAGGTTCAGCAAGCTGTTGCTTCTGTCC
GAATAAAGAATGGAGAAATA

Downstream 100 bases:

>100_bases
TTGGACTACTCTATCAGCATAAAAAAATCATCAGTAGAGCTGATGATTGTCACAAAAAAATTAGGAGAAAAAATGACCGA
AAATAATCGTCTGTCAGTAA

Product: dihydroorotate dehydrogenase electron transfer subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MPKLQEMMTIVSQREVASNIFEMVLKGELVEEMDLPGQFLHLAVPNASMLLRRPISISSWDKVAKTCTILYRIGDETSGT
YEISKLQSGAKIDVMGPLGNGFPVDEVVSTDKILIVGGGIGVPPLYELAKQLEEKNCQMTILLGFASEKVKILEKEFAEL
KNVSLKIATDDGSYGTKGHVGMLMEEIDFEVDALYTCGAPAMLKAVAKKYEQLERLYISMESRMACGIGACYACVEHDKE
DENHALKVCEDGPVFLGKQLLL

Sequences:

>Translated_262_residues
MPKLQEMMTIVSQREVASNIFEMVLKGELVEEMDLPGQFLHLAVPNASMLLRRPISISSWDKVAKTCTILYRIGDETSGT
YEISKLQSGAKIDVMGPLGNGFPVDEVVSTDKILIVGGGIGVPPLYELAKQLEEKNCQMTILLGFASEKVKILEKEFAEL
KNVSLKIATDDGSYGTKGHVGMLMEEIDFEVDALYTCGAPAMLKAVAKKYEQLERLYISMESRMACGIGACYACVEHDKE
DENHALKVCEDGPVFLGKQLLL
>Mature_261_residues
PKLQEMMTIVSQREVASNIFEMVLKGELVEEMDLPGQFLHLAVPNASMLLRRPISISSWDKVAKTCTILYRIGDETSGTY
EISKLQSGAKIDVMGPLGNGFPVDEVVSTDKILIVGGGIGVPPLYELAKQLEEKNCQMTILLGFASEKVKILEKEFAELK
NVSLKIATDDGSYGTKGHVGMLMEEIDFEVDALYTCGAPAMLKAVAKKYEQLERLYISMESRMACGIGACYACVEHDKED
ENHALKVCEDGPVFLGKQLLL

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrDB subunit to the ultimate electron acceptor NAD(+)

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRK_LACLA (Q9CFW7)

Other databases:

- EMBL:   AE005176
- PIR:   C86793
- RefSeq:   NP_267503.1
- ProteinModelPortal:   Q9CFW7
- SMR:   Q9CFW7
- GeneID:   1114997
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L183563
- NMPDR:   fig|272623.1.peg.1382
- HOGENOM:   HBG730970
- OMA:   RPISICS
- ProtClustDB:   CLSK697702
- BioCyc:   LLAC272623:L183563-MONOMER
- BioCyc:   MetaCyc:MONOMER-14472
- GO:   GO:0006810
- HAMAP:   MF_01211_B
- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938
- PIRSF:   PIRSF006816

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1; SSF63380 Riboflavin_synthase_like_b-brl

EC number: NA

Molecular weight: Translated: 28832; Mature: 28701

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS51384 FAD_FR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLQEMMTIVSQREVASNIFEMVLKGELVEEMDLPGQFLHLAVPNASMLLRRPISISSW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCHH
DKVAKTCTILYRIGDETSGTYEISKLQSGAKIDVMGPLGNGFPVDEVVSTDKILIVGGGI
HHHHHHHHEEEEECCCCCCEEEEHECCCCCEEEEECCCCCCCCHHHHHCCCEEEEEECCC
GVPPLYELAKQLEEKNCQMTILLGFASEKVKILEKEFAELKNVSLKIATDDGSYGTKGHV
CCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHH
GMLMEEIDFEVDALYTCGAPAMLKAVAKKYEQLERLYISMESRMACGIGACYACVEHDKE
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DENHALKVCEDGPVFLGKQLLL
CCCCEEEEECCCCEEHHHHHCC
>Mature Secondary Structure 
PKLQEMMTIVSQREVASNIFEMVLKGELVEEMDLPGQFLHLAVPNASMLLRRPISISSW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCHH
DKVAKTCTILYRIGDETSGTYEISKLQSGAKIDVMGPLGNGFPVDEVVSTDKILIVGGGI
HHHHHHHHEEEEECCCCCCEEEEHECCCCCEEEEECCCCCCCCHHHHHCCCEEEEEECCC
GVPPLYELAKQLEEKNCQMTILLGFASEKVKILEKEFAELKNVSLKIATDDGSYGTKGHV
CCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHH
GMLMEEIDFEVDALYTCGAPAMLKAVAKKYEQLERLYISMESRMACGIGACYACVEHDKE
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DENHALKVCEDGPVFLGKQLLL
CCCCEEEEECCCCEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471