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The map label for this gene is pabA

Identifier: 15673297

GI number: 15673297

Start: 1348464

End: 1349045

Strand: Reverse

Name: pabA

Synonym: L0178

Alternate gene names: 15673297

Gene position: 1349045-1348464 (Counterclockwise)

Preceding gene: 15673298

Following gene: 15673296

Centisome position: 57.03

GC content: 33.33

Gene sequence:

>582_bases
ATGAAATTGCTATTAATTGATAATTATGATTCTTTTACTTATTTGCTTGCACAGTATTTTGAGGAATTAGATTGTAGTGT
AACAGTGGTTAATGACCAAGATAAAATGAGTCAGAAAATTAGAATTTCTCCGGATTTTATTTGTGAAAATTATGATGCGA
TTATCATTTCTCCAGGTCCAAAAACACCAAAAGAAGCCGTTTTTAGTAGGGATGTAGTTCAACTATACGCTGGAAAAATT
CCTATGTTAGGAATTTGCTTGGGTCAGCAAGTCATTGCTGAATGTTTTGGAGGAAATGTTGTTCTTGGTGAGAGGCCAAT
GCATGGAAAAATTTCTGTCATTCGTCATAATTGTCAAGGAATTTTTAAAGGACTTCCACAAAATTTGAAAGTTGCACGTT
ATCATTCGTTGATTGTCGATAAACTACCTAATGATTTTGAAATTGATGCGCAGAGTGAGGATGGTGTTATTCAGGCCATT
CATCAGCCAAAATTAAAATTGTGGGCTTTACAATTTCACCCAGAAAGTTTAGTTACTGAATATGGTCATGAAATGTTAAA
TAATTTTTTGAAAGTGGTGTAG

Upstream 100 bases:

>100_bases
TTAATTTATGAGGAAATATTCGCTTTATAGATTTGAAATTAGACTGATTAAAATACTTAACTTAATAAATATTTTAGTAT
AATTAAAAAAGGAGGCTGAA

Downstream 100 bases:

>100_bases
TCTTTTGAAGGAATTTATAATAAAAAATACGGATATTTGGAAAATTTTCCTAAAATATTATCGGTCAGATGAAGAAATTG
TTTTTTTACATAGTAGTCAG

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKLLLIDNYDSFTYLLAQYFEELDCSVTVVNDQDKMSQKIRISPDFICENYDAIIISPGPKTPKEAVFSRDVVQLYAGKI
PMLGICLGQQVIAECFGGNVVLGERPMHGKISVIRHNCQGIFKGLPQNLKVARYHSLIVDKLPNDFEIDAQSEDGVIQAI
HQPKLKLWALQFHPESLVTEYGHEMLNNFLKVV

Sequences:

>Translated_193_residues
MKLLLIDNYDSFTYLLAQYFEELDCSVTVVNDQDKMSQKIRISPDFICENYDAIIISPGPKTPKEAVFSRDVVQLYAGKI
PMLGICLGQQVIAECFGGNVVLGERPMHGKISVIRHNCQGIFKGLPQNLKVARYHSLIVDKLPNDFEIDAQSEDGVIQAI
HQPKLKLWALQFHPESLVTEYGHEMLNNFLKVV
>Mature_193_residues
MKLLLIDNYDSFTYLLAQYFEELDCSVTVVNDQDKMSQKIRISPDFICENYDAIIISPGPKTPKEAVFSRDVVQLYAGKI
PMLGICLGQQVIAECFGGNVVLGERPMHGKISVIRHNCQGIFKGLPQNLKVARYHSLIVDKLPNDFEIDAQSEDGVIQAI
HQPKLKLWALQFHPESLVTEYGHEMLNNFLKVV

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=146, Percent_Identity=32.8767123287671, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1789760, Length=191, Percent_Identity=48.6910994764398, Blast_Score=174, Evalue=4e-45,
Organism=Escherichia coli, GI1787517, Length=188, Percent_Identity=35.6382978723404, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1788854, Length=200, Percent_Identity=26.5, Blast_Score=65, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=193, Percent_Identity=40.9326424870466, Blast_Score=151, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6324361, Length=217, Percent_Identity=31.7972350230415, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281365319, Length=144, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 21823; Mature: 21823

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLLIDNYDSFTYLLAQYFEELDCSVTVVNDQDKMSQKIRISPDFICENYDAIIISPGP
CEEEEEECCCHHHHHHHHHHHHCCCEEEEECCHHHHHCEECCCHHHEECCCCEEEECCCC
KTPKEAVFSRDVVQLYAGKIPMLGICLGQQVIAECFGGNVVLGERPMHGKISVIRHNCQG
CCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHH
IFKGLPQNLKVARYHSLIVDKLPNDFEIDAQSEDGVIQAIHQPKLKLWALQFHPESLVTE
HHHCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHCCCCEEEEEEEECCHHHHHH
YGHEMLNNFLKVV
HHHHHHHHHHHCC
>Mature Secondary Structure
MKLLLIDNYDSFTYLLAQYFEELDCSVTVVNDQDKMSQKIRISPDFICENYDAIIISPGP
CEEEEEECCCHHHHHHHHHHHHCCCEEEEECCHHHHHCEECCCHHHEECCCCEEEECCCC
KTPKEAVFSRDVVQLYAGKIPMLGICLGQQVIAECFGGNVVLGERPMHGKISVIRHNCQG
CCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHH
IFKGLPQNLKVARYHSLIVDKLPNDFEIDAQSEDGVIQAIHQPKLKLWALQFHPESLVTE
HHHCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHCCCCEEEEEEEECCHHHHHH
YGHEMLNNFLKVV
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3894673; 2403545; 11677609 [H]