Click here to switch to the map view.

The map label for this gene is pabB

Identifier: 15673296

GI number: 15673296

Start: 1346573

End: 1348459

Strand: Reverse

Name: pabB

Synonym: L0179

Alternate gene names: 15673296

Gene position: 1348459-1346573 (Counterclockwise)

Preceding gene: 15673297

Following gene: 30024036

Centisome position: 57.0

GC content: 34.5

Gene sequence:

>1887_bases
TTGAAGGAATTTATAATAAAAAATACGGATATTTGGAAAATTTTCCTAAAATATTATCGGTCAGATGAAGAAATTGTTTT
TTTACATAGTAGTCAGGTGACCGAAAATGAGCATTATAGTATTTTAGCTCATAAACCTTATAAAAAGGTTTCAAAATATA
AGGGTCAAGTGTTTTTTAATGGTGAAAAAAAGAAGTTCAATTTTTTAGATGCGGTAGATTTGCTGAAGGATGAGAGAGTT
GAACGACCTAAAAATTGGCCTTTTTATCCAGAATTATTGGGTTTTGTAAGTTATGAGCAAGATCCGGCTTGTTTTGCAGC
TTATGATGAAGTTTTACTTTTTGACCATAGAACAAAACTGTTACGTGTCGTGCAATTTGAACAAACTGATGGCCAATATT
GGCTGACTGAATCGGAAGAAATTGAAGTGGATTCAGAGATTGAGTTCGATGGTCAGAATGGCATAGGGGCTATTTTTATT
GACCAAACGAGGCAAGAATATATTGCTTCAATAAAAAAATTACAAGATTATATGAAGGCTGGCGATATCTATGTTGCCAA
TTTGACGCAACAATTTGAAATTTGGTCCGATCAAAAACCTATTGAAGTTTTTAAGAAAACAAGGAAACAAATTCCAGCTC
CTTTCTCATCATTTTTACAATATCCTGAATGGAAAATGACGCAAATTTCAAGTTCAGTGGAACGCTTTGTTTCTATTCAT
GATGGAGCATTAATTTCAAAACCAATTAAAGGAACAATTGCCAGAGGAGAAGATGTTGGAGCTGATAGATTACAAAAGGA
AATACTTTCCGACAGTAGTAAAGAACGGTCTGAGTTACTGATGGTGACGGATTTATTGCGTAATGATATTGTCCGAATTA
GTCAACCTTTTTCTTTGTCTGTCCCTAAATTTGCAGAAATTGAAACTTTTTCTCATGTTCATCAACTGGTGACTTCAATA
AAAAGTAGAATTAAAGAAGATTTGACTTTTTCAGAATTTATGACGGCTTTATTCCCGGGAGGGTCAATCACAGGTACACC
TAAGAAGCGGGCAATGGAGATTATTAAGGAAGTTGAAAAACAACCTAGAGGAATTTATACAGGGATGCAGGGTTGGTTAA
GTCGAGAAATGGATTTGGATATGAACATCGTGATTCGGACATTAGTTCATGACGGTGAGCATTATCAACTTGGTGTAGGC
GGTGGAATTACGTTCGAGAGCAAAGCAGAAGCAGAGTTTTCAGAGATTTTACTAAAAGCAAAACCCTTTTTAGATATTTT
AGGTGTAAAAGATGTTCCAAGTATTTTATTTACAACAGGCATTATTAAAAATGGTGAATTGTTAAATTTAGAGGGTCATG
TCAATCGCTTGAAAAAACAATACCATCATCCAGATTTGGAAGAAAAATTGAGAATATTTGCCCAAAATGTTACTGACGGC
GTTTTACGTATCAGTACTGACGGAGATTCTTTGTCCCCTGGGATTCGTCAGCTGACGCATTCAAATGAGGCCTATCGAGT
TAAACTGTCGTCAATTAATGACAAACCTAGTCTTTTGTCTAACTTTAAACTTTCAGGCCCAGATTTTCAAAAGGTCTTTC
GTCAGGAAGTCTTAGAAGCGAAAAAAGAAGGGTTTCAAGATATTCTATTTCATACAGATGGTTTGATCAGTGAATTATCA
ATCGGAAATTTTGTGGCAAAAAAGGGGAATCAGTACGAAACGCCAGCCAAATATGCTCTAAAAGGAACTTTTTTAGATTT
ATTTGCGAAAAATCATACGCTAATATATAAAGATATTGCCCTTTCTGATTTGAAAACATATGATTGTTTTTATATGACAA
ATGCTGTCAGAGGATTAGTTGAAATAAAAATTGATGGAATTTCCTAA

Upstream 100 bases:

>100_bases
CCAAAATTAAAATTGTGGGCTTTACAATTTCACCCAGAAAGTTTAGTTACTGAATATGGTCATGAAATGTTAAATAATTT
TTTGAAAGTGGTGTAGTCTT

Downstream 100 bases:

>100_bases
TATAAGTCCTTGGTTTTACTGACCAAGGACTTTTTTTGGAGCAAAAATTACTGACAGAATCTGTCAGTAAAAATATTCTA
AAATTTTACTGACAAAAATA

Product: para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 628; Mature: 628

Protein sequence:

>628_residues
MKEFIIKNTDIWKIFLKYYRSDEEIVFLHSSQVTENEHYSILAHKPYKKVSKYKGQVFFNGEKKKFNFLDAVDLLKDERV
ERPKNWPFYPELLGFVSYEQDPACFAAYDEVLLFDHRTKLLRVVQFEQTDGQYWLTESEEIEVDSEIEFDGQNGIGAIFI
DQTRQEYIASIKKLQDYMKAGDIYVANLTQQFEIWSDQKPIEVFKKTRKQIPAPFSSFLQYPEWKMTQISSSVERFVSIH
DGALISKPIKGTIARGEDVGADRLQKEILSDSSKERSELLMVTDLLRNDIVRISQPFSLSVPKFAEIETFSHVHQLVTSI
KSRIKEDLTFSEFMTALFPGGSITGTPKKRAMEIIKEVEKQPRGIYTGMQGWLSREMDLDMNIVIRTLVHDGEHYQLGVG
GGITFESKAEAEFSEILLKAKPFLDILGVKDVPSILFTTGIIKNGELLNLEGHVNRLKKQYHHPDLEEKLRIFAQNVTDG
VLRISTDGDSLSPGIRQLTHSNEAYRVKLSSINDKPSLLSNFKLSGPDFQKVFRQEVLEAKKEGFQDILFHTDGLISELS
IGNFVAKKGNQYETPAKYALKGTFLDLFAKNHTLIYKDIALSDLKTYDCFYMTNAVRGLVEIKIDGIS

Sequences:

>Translated_628_residues
MKEFIIKNTDIWKIFLKYYRSDEEIVFLHSSQVTENEHYSILAHKPYKKVSKYKGQVFFNGEKKKFNFLDAVDLLKDERV
ERPKNWPFYPELLGFVSYEQDPACFAAYDEVLLFDHRTKLLRVVQFEQTDGQYWLTESEEIEVDSEIEFDGQNGIGAIFI
DQTRQEYIASIKKLQDYMKAGDIYVANLTQQFEIWSDQKPIEVFKKTRKQIPAPFSSFLQYPEWKMTQISSSVERFVSIH
DGALISKPIKGTIARGEDVGADRLQKEILSDSSKERSELLMVTDLLRNDIVRISQPFSLSVPKFAEIETFSHVHQLVTSI
KSRIKEDLTFSEFMTALFPGGSITGTPKKRAMEIIKEVEKQPRGIYTGMQGWLSREMDLDMNIVIRTLVHDGEHYQLGVG
GGITFESKAEAEFSEILLKAKPFLDILGVKDVPSILFTTGIIKNGELLNLEGHVNRLKKQYHHPDLEEKLRIFAQNVTDG
VLRISTDGDSLSPGIRQLTHSNEAYRVKLSSINDKPSLLSNFKLSGPDFQKVFRQEVLEAKKEGFQDILFHTDGLISELS
IGNFVAKKGNQYETPAKYALKGTFLDLFAKNHTLIYKDIALSDLKTYDCFYMTNAVRGLVEIKIDGIS
>Mature_628_residues
MKEFIIKNTDIWKIFLKYYRSDEEIVFLHSSQVTENEHYSILAHKPYKKVSKYKGQVFFNGEKKKFNFLDAVDLLKDERV
ERPKNWPFYPELLGFVSYEQDPACFAAYDEVLLFDHRTKLLRVVQFEQTDGQYWLTESEEIEVDSEIEFDGQNGIGAIFI
DQTRQEYIASIKKLQDYMKAGDIYVANLTQQFEIWSDQKPIEVFKKTRKQIPAPFSSFLQYPEWKMTQISSSVERFVSIH
DGALISKPIKGTIARGEDVGADRLQKEILSDSSKERSELLMVTDLLRNDIVRISQPFSLSVPKFAEIETFSHVHQLVTSI
KSRIKEDLTFSEFMTALFPGGSITGTPKKRAMEIIKEVEKQPRGIYTGMQGWLSREMDLDMNIVIRTLVHDGEHYQLGVG
GGITFESKAEAEFSEILLKAKPFLDILGVKDVPSILFTTGIIKNGELLNLEGHVNRLKKQYHHPDLEEKLRIFAQNVTDG
VLRISTDGDSLSPGIRQLTHSNEAYRVKLSSINDKPSLLSNFKLSGPDFQKVFRQEVLEAKKEGFQDILFHTDGLISELS
IGNFVAKKGNQYETPAKYALKGTFLDLFAKNHTLIYKDIALSDLKTYDCFYMTNAVRGLVEIKIDGIS

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=412, Percent_Identity=31.5533980582524, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1787518, Length=279, Percent_Identity=28.3154121863799, Blast_Score=119, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6320935, Length=259, Percent_Identity=32.8185328185328, Blast_Score=140, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6324361, Length=290, Percent_Identity=29.3103448275862, Blast_Score=119, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 71987; Mature: 71987

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEFIIKNTDIWKIFLKYYRSDEEIVFLHSSQVTENEHYSILAHKPYKKVSKYKGQVFFN
CCCCEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCHHHHHHCCCCEEEC
GEKKKFNFLDAVDLLKDERVERPKNWPFYPELLGFVSYEQDPACFAAYDEVLLFDHRTKL
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHEEHHHHHH
LRVVQFEQTDGQYWLTESEEIEVDSEIEFDGQNGIGAIFIDQTRQEYIASIKKLQDYMKA
HHHHEEECCCCCEEECCCCCCCCCCCEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHC
GDIYVANLTQQFEIWSDQKPIEVFKKTRKQIPAPFSSFLQYPEWKMTQISSSVERFVSIH
CCEEEEECCHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHC
DGALISKPIKGTIARGEDVGADRLQKEILSDSSKERSELLMVTDLLRNDIVRISQPFSLS
CCCEECCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEECCCCCCCC
VPKFAEIETFSHVHQLVTSIKSRIKEDLTFSEFMTALFPGGSITGTPKKRAMEIIKEVEK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
QPRGIYTGMQGWLSREMDLDMNIVIRTLVHDGEHYQLGVGGGITFESKAEAEFSEILLKA
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHHC
KPFLDILGVKDVPSILFTTGIIKNGELLNLEGHVNRLKKQYHHPDLEEKLRIFAQNVTDG
CCCHHHCCCCCHHHHHHHHCEECCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
VLRISTDGDSLSPGIRQLTHSNEAYRVKLSSINDKPSLLSNFKLSGPDFQKVFRQEVLEA
EEEEECCCCCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHH
KKEGFQDILFHTDGLISELSIGNFVAKKGNQYETPAKYALKGTFLDLFAKNHTLIYKDIA
HHCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHH
LSDLKTYDCFYMTNAVRGLVEIKIDGIS
HHHCCHHHHHHHHHHHCEEEEEEEECCC
>Mature Secondary Structure
MKEFIIKNTDIWKIFLKYYRSDEEIVFLHSSQVTENEHYSILAHKPYKKVSKYKGQVFFN
CCCCEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCHHHHHHCCCCEEEC
GEKKKFNFLDAVDLLKDERVERPKNWPFYPELLGFVSYEQDPACFAAYDEVLLFDHRTKL
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHEEHHHHHH
LRVVQFEQTDGQYWLTESEEIEVDSEIEFDGQNGIGAIFIDQTRQEYIASIKKLQDYMKA
HHHHEEECCCCCEEECCCCCCCCCCCEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHC
GDIYVANLTQQFEIWSDQKPIEVFKKTRKQIPAPFSSFLQYPEWKMTQISSSVERFVSIH
CCEEEEECCHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHC
DGALISKPIKGTIARGEDVGADRLQKEILSDSSKERSELLMVTDLLRNDIVRISQPFSLS
CCCEECCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEECCCCCCCC
VPKFAEIETFSHVHQLVTSIKSRIKEDLTFSEFMTALFPGGSITGTPKKRAMEIIKEVEK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
QPRGIYTGMQGWLSREMDLDMNIVIRTLVHDGEHYQLGVGGGITFESKAEAEFSEILLKA
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHHC
KPFLDILGVKDVPSILFTTGIIKNGELLNLEGHVNRLKKQYHHPDLEEKLRIFAQNVTDG
CCCHHHCCCCCHHHHHHHHCEECCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
VLRISTDGDSLSPGIRQLTHSNEAYRVKLSSINDKPSLLSNFKLSGPDFQKVFRQEVLEA
EEEEECCCCCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHH
KKEGFQDILFHTDGLISELSIGNFVAKKGNQYETPAKYALKGTFLDLFAKNHTLIYKDIA
HHCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHH
LSDLKTYDCFYMTNAVRGLVEIKIDGIS
HHHCCHHHHHHHHHHHCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 11677609; 2251281 [H]