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The map label for this gene is ceo

Identifier: 15673219

GI number: 15673219

Start: 1264586

End: 1265515

Strand: Reverse

Name: ceo

Synonym: L64332

Alternate gene names: 15673219

Gene position: 1265515-1264586 (Counterclockwise)

Preceding gene: 15673220

Following gene: 30024030

Centisome position: 53.5

GC content: 33.44

Gene sequence:

>930_bases
ATGAAAATTGGCCTAGTAAAAACAAACTTCCCAGGAGAGAGACGAGTCCCACTTCTACCAAAAGACATTAAAGATTTTAA
AAATGAAATATTAGTAGAGGAGGGGTTTGGAAAATTTTTAGATATTGATGATCAAGAATACATTGATAAAGGATGTCATA
TTTTATCAAGAGCTGAGGTTTTTTCGGAATCAGAGGCAATCTTCTCACTAAAACTCATCCAGCCTACTGATTACCCTTAT
CTTAGAGAGGGGCAGATGATTATAGGGTGGACACATCCTTTTGGTTCAGGACGATTATTCATGAAAGAGCAAGCTCTACC
TAAAAAGTTAATTGTAGTAGATTTAGATAGTAATTCACCTTGTATTTATTATGAAAATGAGATATTTGAATCAGGTATTC
CGAAGGGACTTTTATATAAAAATAGTTTTTACGCAGGCTATGCAGGTGTCCTTGATGCTTTATTGCAATATGGATTTATT
CCAACTGAAGAGACAAAAATAGCTATTTTAGGTTCCGGAAATGTTGCACAGGGTGCCTTTAGTAGTATCTCAAAATATTC
CTCAAACATCCGAATGTATTATCGAAAAACAATGTCCATCTTCAAAGAAAATTATACAAAGTACGACATCATCATCAATG
GAATTGAAATTGGGAAAGAGGATGATCCAATTTTAAGCTTTTCAGAACAAAAATCATTGAAAAAAGGGACTTTTATTATT
GATGTAGCAGCTGATGCTGGAAATACTATTGAAGGAACGCATTTTACTAGTATGGATGACCCCATCTACGAAAATGATGG
AAAATACTATTATGTTGTTCCTAATACTCCATCACTGATCTACCGAAATGTGAGTCAAGATTTAAGTAAGATTTTGAGCG
AGAATATCTTTAGTGAAGATTGTTCACGATTTTTAAGTATTAAATCTTGA

Upstream 100 bases:

>100_bases
TTGTTTCGCTTCTAATCAGTGTATTAGTTTGGTACTGGTTAAAAAAGAAAAAAACTTTTTAGAGAAATTTATAAAATTAT
AGAAAGAAGAAGGAAAAACT

Downstream 100 bases:

>100_bases
AGAAACAATTATATTTCTTTGAGTATTAATTCCATTGCCGCAGCAGCAATAGTAGCAAAAAATATATTAGCTCATTCTAT
CACCAATTACATTAAAATAA

Product: N5-carboxyethyl-ornithine synthase

Products: NA

Alternate protein names: CEOS; N(5)-(L-1-carboxyethyl)-L-ornithine:NADP(+) oxidoreductase [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKIGLVKTNFPGERRVPLLPKDIKDFKNEILVEEGFGKFLDIDDQEYIDKGCHILSRAEVFSESEAIFSLKLIQPTDYPY
LREGQMIIGWTHPFGSGRLFMKEQALPKKLIVVDLDSNSPCIYYENEIFESGIPKGLLYKNSFYAGYAGVLDALLQYGFI
PTEETKIAILGSGNVAQGAFSSISKYSSNIRMYYRKTMSIFKENYTKYDIIINGIEIGKEDDPILSFSEQKSLKKGTFII
DVAADAGNTIEGTHFTSMDDPIYENDGKYYYVVPNTPSLIYRNVSQDLSKILSENIFSEDCSRFLSIKS

Sequences:

>Translated_309_residues
MKIGLVKTNFPGERRVPLLPKDIKDFKNEILVEEGFGKFLDIDDQEYIDKGCHILSRAEVFSESEAIFSLKLIQPTDYPY
LREGQMIIGWTHPFGSGRLFMKEQALPKKLIVVDLDSNSPCIYYENEIFESGIPKGLLYKNSFYAGYAGVLDALLQYGFI
PTEETKIAILGSGNVAQGAFSSISKYSSNIRMYYRKTMSIFKENYTKYDIIINGIEIGKEDDPILSFSEQKSLKKGTFII
DVAADAGNTIEGTHFTSMDDPIYENDGKYYYVVPNTPSLIYRNVSQDLSKILSENIFSEDCSRFLSIKS
>Mature_309_residues
MKIGLVKTNFPGERRVPLLPKDIKDFKNEILVEEGFGKFLDIDDQEYIDKGCHILSRAEVFSESEAIFSLKLIQPTDYPY
LREGQMIIGWTHPFGSGRLFMKEQALPKKLIVVDLDSNSPCIYYENEIFESGIPKGLLYKNSFYAGYAGVLDALLQYGFI
PTEETKIAILGSGNVAQGAFSSISKYSSNIRMYYRKTMSIFKENYTKYDIIINGIEIGKEDDPILSFSEQKSLKKGTFII
DVAADAGNTIEGTHFTSMDDPIYENDGKYYYVVPNTPSLIYRNVSQDLSKILSENIFSEDCSRFLSIKS

Specific function: Catalyzes the NADPH-dependent reductive condensation between pyruvic acid and the side chain amino group of L-ornithine to form N(5)-(L-1-carboxyethyl)-L-ornithine. To a lesser extent, can also use L-lysine as substrate (yielding N(6)-(L-1- carboxyethyl)-

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family. CEOS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR007886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.5.1.24 [H]

Molecular weight: Translated: 35008; Mature: 35008

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGLVKTNFPGERRVPLLPKDIKDFKNEILVEEGFGKFLDIDDQEYIDKGCHILSRAEV
CEEEEEECCCCCCCCCCCCCHHHHHHHHHEEEECCCCCEECCCCHHHHHHHHHHHHHHHH
FSESEAIFSLKLIQPTDYPYLREGQMIIGWTHPFGSGRLFMKEQALPKKLIVVDLDSNSP
HCCCCEEEEEEEECCCCCCEEECCCEEEEEECCCCCCEEEEECCCCCCEEEEEEECCCCC
CIYYENEIFESGIPKGLLYKNSFYAGYAGVLDALLQYGFIPTEETKIAILGSGNVAQGAF
EEEECHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHH
SSISKYSSNIRMYYRKTMSIFKENYTKYDIIINGIEIGKEDDPILSFSEQKSLKKGTFII
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCHHHHCCCCCCEEE
DVAADAGNTIEGTHFTSMDDPIYENDGKYYYVVPNTPSLIYRNVSQDLSKILSENIFSED
EEECCCCCCCCCCEECCCCCCCEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
CSRFLSIKS
HHHHHCCCC
>Mature Secondary Structure
MKIGLVKTNFPGERRVPLLPKDIKDFKNEILVEEGFGKFLDIDDQEYIDKGCHILSRAEV
CEEEEEECCCCCCCCCCCCCHHHHHHHHHEEEECCCCCEECCCCHHHHHHHHHHHHHHHH
FSESEAIFSLKLIQPTDYPYLREGQMIIGWTHPFGSGRLFMKEQALPKKLIVVDLDSNSP
HCCCCEEEEEEEECCCCCCEEECCCEEEEEECCCCCCEEEEECCCCCCEEEEEEECCCCC
CIYYENEIFESGIPKGLLYKNSFYAGYAGVLDALLQYGFIPTEETKIAILGSGNVAQGAF
EEEECHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHH
SSISKYSSNIRMYYRKTMSIFKENYTKYDIIINGIEIGKEDDPILSFSEQKSLKKGTFII
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCHHHHCCCCCCEEE
DVAADAGNTIEGTHFTSMDDPIYENDGKYYYVVPNTPSLIYRNVSQDLSKILSENIFSED
EEECCCCCCCCCCEECCCCCCCEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
CSRFLSIKS
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7744873; 2498334; 10548058; 10525296 [H]