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The map label for this gene is ftsW1

Identifier: 15672650

GI number: 15672650

Start: 662276

End: 663538

Strand: Direct

Name: ftsW1

Synonym: L62179

Alternate gene names: 15672650

Gene position: 662276-663538 (Clockwise)

Preceding gene: 15672649

Following gene: 15672651

Centisome position: 28.0

GC content: 35.39

Gene sequence:

>1263_bases
ATGAATTTAAATAAGAATAATTTTTTAAACTACTCTATATTGATTCCATACCTAATTCTTGCAGGAATTGGTATTGTGAT
GGTTTTTTCAACCACGGTTCCTGATCAGTTACAAAAAGGATTAAATCCTTATAAATTAGTAATTAACCAAACAGCATTCG
AATTATTGAGTCTCATTATGATTGCAGTGATTTACCGTCTGAAACTTAGAGCCCTTAAGAATAGAAAAATGATAGGAACA
ATAATGGTTATTTTGATTCTGTCATTAATATTTTGTAGGATAATGCCTTCCAGTTTTGCTCTGACAGCACCCGTAAATGG
AGCCAGAGGTTGGATTCATATTCCAGGAATCGGAACTGTGCAGCCAGCAGAATTTGCCAAAGTTTTTATTATCTGGTATT
TAGCCTCAGTTTTTTCAACAAAACAAGAAGAAATTGAAAAACGTGATATAAATGAGATTTTTAAAGGAAAGACGCTCTTT
CAAAAACTTTTTGGTGGTTGGCGATTACCCGTAGTTGCCATTTTATTGGTTGACCTTATCATGCCTGACCTAGGTAATAC
TTTGATTATTGCTGCAGTTGCTTTGATAATGATTGGAGCCAGCGGTATATCTTGGCGTTGGTATTCCGGCTATTCAAAAT
TAATTCTATCTTTGATGGCCATTTTCTTAGGATTTCTTTTCATTGTAGGTGGAAATATCATTCCAAGTTTCTTACCCATC
ACTTATATCAATAAACGATTTGAAGCTTTTGTTAATCCTTTTACAGACTTAGCCAATTCTGGACACCAGTTAGCTAATTC
ATACTATGCTATAGTTAATGGTGGTTGGACAGGGCGTGGTTTAGGAAATTCGATTCAAAAAAATGGTTTCTTACCAGAAG
CTCAAACTGACTTTATCTTTCCAATTGTCGTGGAAGAATTAGGAATCATTGGCGGAATTATTATTCTAGCTATTCTCTTT
TTCTTGATAAGCAGAATGTTAATTGTTGGAATTCGTGCTAAAAGTGCCTTTAACTCACTCATTATGATTGGGGTATCTGG
TTTATTGTTAGTTCAAGTCTTTGTCAATGTGGGTGGAGCAATCGGAATTATTCCAGAAACAGGAGTAACCTTCCCCTTCC
TATCACAAGGAGGGTCGTCCTTCCTTGGCTTATCGTTGGGAATTGCATTTGCATTAAATATTTCAGCTGATGAGAAACGA
AGAGAAGTTTCTGAGCTCTCAAATCATTATAGTAGCAGTGTCCCAACTTATGAAAACGATTGA

Upstream 100 bases:

>100_bases
AATACCTTATCTTTGGGTGGTAGAAACTTATAAGCACTTTGAAAATCTTTATAAATTATTCAACTCATGCTATAATAATA
TGAATGAGGAAAAAAAGATA

Downstream 100 bases:

>100_bases
CAATTGTCAGTCGTTTAAAAGTGTATAAAAGATTTTTATAATATATGAAAGAGTGAAAGGTAATGACCAATTACCTTTCC
AAGCAAGCCTCATTAAGGAG

Product: FtsW1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MNLNKNNFLNYSILIPYLILAGIGIVMVFSTTVPDQLQKGLNPYKLVINQTAFELLSLIMIAVIYRLKLRALKNRKMIGT
IMVILILSLIFCRIMPSSFALTAPVNGARGWIHIPGIGTVQPAEFAKVFIIWYLASVFSTKQEEIEKRDINEIFKGKTLF
QKLFGGWRLPVVAILLVDLIMPDLGNTLIIAAVALIMIGASGISWRWYSGYSKLILSLMAIFLGFLFIVGGNIIPSFLPI
TYINKRFEAFVNPFTDLANSGHQLANSYYAIVNGGWTGRGLGNSIQKNGFLPEAQTDFIFPIVVEELGIIGGIIILAILF
FLISRMLIVGIRAKSAFNSLIMIGVSGLLLVQVFVNVGGAIGIIPETGVTFPFLSQGGSSFLGLSLGIAFALNISADEKR
REVSELSNHYSSSVPTYEND

Sequences:

>Translated_420_residues
MNLNKNNFLNYSILIPYLILAGIGIVMVFSTTVPDQLQKGLNPYKLVINQTAFELLSLIMIAVIYRLKLRALKNRKMIGT
IMVILILSLIFCRIMPSSFALTAPVNGARGWIHIPGIGTVQPAEFAKVFIIWYLASVFSTKQEEIEKRDINEIFKGKTLF
QKLFGGWRLPVVAILLVDLIMPDLGNTLIIAAVALIMIGASGISWRWYSGYSKLILSLMAIFLGFLFIVGGNIIPSFLPI
TYINKRFEAFVNPFTDLANSGHQLANSYYAIVNGGWTGRGLGNSIQKNGFLPEAQTDFIFPIVVEELGIIGGIIILAILF
FLISRMLIVGIRAKSAFNSLIMIGVSGLLLVQVFVNVGGAIGIIPETGVTFPFLSQGGSSFLGLSLGIAFALNISADEKR
REVSELSNHYSSSVPTYEND
>Mature_420_residues
MNLNKNNFLNYSILIPYLILAGIGIVMVFSTTVPDQLQKGLNPYKLVINQTAFELLSLIMIAVIYRLKLRALKNRKMIGT
IMVILILSLIFCRIMPSSFALTAPVNGARGWIHIPGIGTVQPAEFAKVFIIWYLASVFSTKQEEIEKRDINEIFKGKTLF
QKLFGGWRLPVVAILLVDLIMPDLGNTLIIAAVALIMIGASGISWRWYSGYSKLILSLMAIFLGFLFIVGGNIIPSFLPI
TYINKRFEAFVNPFTDLANSGHQLANSYYAIVNGGWTGRGLGNSIQKNGFLPEAQTDFIFPIVVEELGIIGGIIILAILF
FLISRMLIVGIRAKSAFNSLIMIGVSGLLLVQVFVNVGGAIGIIPETGVTFPFLSQGGSSFLGLSLGIAFALNISADEKR
REVSELSNHYSSSVPTYEND

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family

Homologues:

Organism=Escherichia coli, GI1786277, Length=395, Percent_Identity=29.873417721519, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786853, Length=348, Percent_Identity=29.0229885057471, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSW_LACLA (P58119)

Other databases:

- EMBL:   AE005176
- PIR:   D86708
- RefSeq:   NP_266824.1
- GeneID:   1114292
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L62179
- NMPDR:   fig|272623.1.peg.686
- HOGENOM:   HBG729614
- OMA:   FNSMMAL
- ProtClustDB:   CLSK2393126
- BioCyc:   LLAC272623:L62179-MONOMER
- InterPro:   IPR001182
- InterPro:   IPR018365

Pfam domain/function: PF01098 FTSW_RODA_SPOVE

EC number: NA

Molecular weight: Translated: 46097; Mature: 46097

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc655490)-; HASH(0xc8bc640)-; HASH(0xcc94600)-; HASH(0xd32c88c)-; HASH(0xd622594)-; HASH(0xd306e3c)-; HASH(0xd673f50)-; HASH(0xd196910)-; HASH(0xbe296a0)-; HASH(0xc94bcf0)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNKNNFLNYSILIPYLILAGIGIVMVFSTTVPDQLQKGLNPYKLVINQTAFELLSLIM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
IAVIYRLKLRALKNRKMIGTIMVILILSLIFCRIMPSSFALTAPVNGARGWIHIPGIGTV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEECCCCCCC
QPAEFAKVFIIWYLASVFSTKQEEIEKRDINEIFKGKTLFQKLFGGWRLPVVAILLVDLI
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MPDLGNTLIIAAVALIMIGASGISWRWYSGYSKLILSLMAIFLGFLFIVGGNIIPSFLPI
HCCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TYINKRFEAFVNPFTDLANSGHQLANSYYAIVNGGWTGRGLGNSIQKNGFLPEAQTDFIF
HHHHHHHHHHHCHHHHHCCCCHHHHHCEEEEEECCCCCCCCCCCHHHCCCCCCCCCCCHH
PIVVEELGIIGGIIILAILFFLISRMLIVGIRAKSAFNSLIMIGVSGLLLVQVFVNVGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IGIIPETGVTFPFLSQGGSSFLGLSLGIAFALNISADEKRREVSELSNHYSSSVPTYEND
EEECCCCCCCCCCHHCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure
MNLNKNNFLNYSILIPYLILAGIGIVMVFSTTVPDQLQKGLNPYKLVINQTAFELLSLIM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
IAVIYRLKLRALKNRKMIGTIMVILILSLIFCRIMPSSFALTAPVNGARGWIHIPGIGTV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEECCCCCCC
QPAEFAKVFIIWYLASVFSTKQEEIEKRDINEIFKGKTLFQKLFGGWRLPVVAILLVDLI
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MPDLGNTLIIAAVALIMIGASGISWRWYSGYSKLILSLMAIFLGFLFIVGGNIIPSFLPI
HCCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TYINKRFEAFVNPFTDLANSGHQLANSYYAIVNGGWTGRGLGNSIQKNGFLPEAQTDFIF
HHHHHHHHHHHCHHHHHCCCCHHHHHCEEEEEECCCCCCCCCCCHHHCCCCCCCCCCCHH
PIVVEELGIIGGIIILAILFFLISRMLIVGIRAKSAFNSLIMIGVSGLLLVQVFVNVGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IGIIPETGVTFPFLSQGGSSFLGLSLGIAFALNISADEKRREVSELSNHYSSSVPTYEND
EEECCCCCCCCCCHHCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471