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The map label for this gene is ygbG

Identifier: 15672612

GI number: 15672612

Start: 618694

End: 619617

Strand: Direct

Name: ygbG

Synonym: L18686

Alternate gene names: 15672612

Gene position: 618694-619617 (Clockwise)

Preceding gene: 15672611

Following gene: 15672613

Centisome position: 26.15

GC content: 38.1

Gene sequence:

>924_bases
ATGGAAATCCAATTTTTAGGGACTGGGGCTGGTCAGCCTTCTAAATCAAGAAACACTCAGGCAATTGCCTTGAAAATGCT
TGATGAGCGTAATGAAATTTGGCTTTTTGACTGTGGTGAAGCAACGCAACATCAAATTTTAAATACGACAATTAAGCCAC
GAAAAATTACTAAGATTTTTATTACACATTTACATGGGGATCATATTTTTGGCTTGCCTGGTTTTTTGTCTAGTAGGAGT
TTTCAAAGTTCAGATGAACAAACTGATTTGGAGCTTTATGGCCCTGTGGGAATTAAAGATTTTGTTTTGACCGCTCTTAG
AATCTCGGGTTCACGCTTAGCTTATCGTATCAATTTTCATGAAATTGATTCGGCTGGAAAAATCTTTGAAGATGATAGTT
TTGAAGTCCATACAGATTTGCTTGACCATACTATTTTCTGCTTGGGTTATCGCGTCGTAGAAAAAAATCGAATAGGTGAA
CTCGATGCCAATGCTTTAAAAGAAGCTGGGCTTCCTTTCGGACCCCTTTTTGGTAAAATAAAAAAAGGTGAGATTGTTCA
GTATGAAGGAAAAACTTTCGATCCTAAAGATTATATCGGAGCGGATAAAGCTGGTAAAATAGTCACGATTTTAGGCGATA
CAAGAAAATCGAATGTTGCAGTACGCTTAGCTTATGGAGCAGACTTATTGGTTCATGAGGCAACTTATGAAGCAAATGAA
AGTAAAATGGCAAAAGCACATGGTCATTCAACGACTAAACAAGCAGCAGACGTCGCCAAAGAAGCCGGAGTTAATCGATT
GTTATTGACTCATATTAGTGCACGCTATGTTGGACCTTTGGTTGGACAATTGGTGCGTGAGGCACAAACTGTTCATTCCA
ACACTTTTGTGGTTAAGGATTTTTACGAGGAAAAAATTGGTTAG

Upstream 100 bases:

>100_bases
GGAGTTTCACAATCTTTTCTTGTTTTGGAAAATAATTCTCATTTTTGAGAAAATAAAGTTTTAATTTGCCTTAAGGTGAG
TTGAAACTGATGGAGGTTCA

Downstream 100 bases:

>100_bases
AAATATTGTAATTACAGGTGCAACTGGTGATATTGCTAAAGAAATTGTCAAATCTTTATCTAAAGAAAATGACCATTTAA
TTTTGGTTTCACGTAGCCGT

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MEIQFLGTGAGQPSKSRNTQAIALKMLDERNEIWLFDCGEATQHQILNTTIKPRKITKIFITHLHGDHIFGLPGFLSSRS
FQSSDEQTDLELYGPVGIKDFVLTALRISGSRLAYRINFHEIDSAGKIFEDDSFEVHTDLLDHTIFCLGYRVVEKNRIGE
LDANALKEAGLPFGPLFGKIKKGEIVQYEGKTFDPKDYIGADKAGKIVTILGDTRKSNVAVRLAYGADLLVHEATYEANE
SKMAKAHGHSTTKQAADVAKEAGVNRLLLTHISARYVGPLVGQLVREAQTVHSNTFVVKDFYEEKIG

Sequences:

>Translated_307_residues
MEIQFLGTGAGQPSKSRNTQAIALKMLDERNEIWLFDCGEATQHQILNTTIKPRKITKIFITHLHGDHIFGLPGFLSSRS
FQSSDEQTDLELYGPVGIKDFVLTALRISGSRLAYRINFHEIDSAGKIFEDDSFEVHTDLLDHTIFCLGYRVVEKNRIGE
LDANALKEAGLPFGPLFGKIKKGEIVQYEGKTFDPKDYIGADKAGKIVTILGDTRKSNVAVRLAYGADLLVHEATYEANE
SKMAKAHGHSTTKQAADVAKEAGVNRLLLTHISARYVGPLVGQLVREAQTVHSNTFVVKDFYEEKIG
>Mature_307_residues
MEIQFLGTGAGQPSKSRNTQAIALKMLDERNEIWLFDCGEATQHQILNTTIKPRKITKIFITHLHGDHIFGLPGFLSSRS
FQSSDEQTDLELYGPVGIKDFVLTALRISGSRLAYRINFHEIDSAGKIFEDDSFEVHTDLLDHTIFCLGYRVVEKNRIGE
LDANALKEAGLPFGPLFGKIKKGEIVQYEGKTFDPKDYIGADKAGKIVTILGDTRKSNVAVRLAYGADLLVHEATYEANE
SKMAKAHGHSTTKQAADVAKEAGVNRLLLTHISARYVGPLVGQLVREAQTVHSNTFVVKDFYEEKIG

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family

Homologues:

Organism=Homo sapiens, GI8922122, Length=333, Percent_Identity=39.3393393393393, Blast_Score=223, Evalue=2e-58,
Organism=Escherichia coli, GI87082078, Length=303, Percent_Identity=46.2046204620462, Blast_Score=269, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNZ_LACLA (Q9CHT8)

Other databases:

- EMBL:   AE005176
- PIR:   F86703
- RefSeq:   NP_266786.1
- ProteinModelPortal:   Q9CHT8
- SMR:   Q9CHT8
- GeneID:   1114250
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L18686
- NMPDR:   fig|272623.1.peg.645
- HOGENOM:   HBG648406
- OMA:   HSTSTMA
- ProtClustDB:   PRK00055
- BioCyc:   LLAC272623:L18686-MONOMER
- BRENDA:   3.1.26.11
- HAMAP:   MF_01818
- InterPro:   IPR001279
- InterPro:   IPR013471
- SMART:   SM00849
- TIGRFAMs:   TIGR02651

Pfam domain/function: PF00753 Lactamase_B

EC number: =3.1.26.11

Molecular weight: Translated: 34035; Mature: 34035

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIQFLGTGAGQPSKSRNTQAIALKMLDERNEIWLFDCGEATQHQILNTTIKPRKITKIF
CEEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHCCCCCCEEEEEE
ITHLHGDHIFGLPGFLSSRSFQSSDEQTDLELYGPVGIKDFVLTALRISGSRLAYRINFH
EEEECCCEEECCCCHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCEEEEEEEHE
EIDSAGKIFEDDSFEVHTDLLDHTIFCLGYRVVEKNRIGELDANALKEAGLPFGPLFGKI
EECCCCCEECCCCCEEHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHCCCCCCHHHCCC
KKGEIVQYEGKTFDPKDYIGADKAGKIVTILGDTRKSNVAVRLAYGADLLVHEATYEANE
CCCCEEEECCCCCCCHHHCCCCCCCCEEEEEECCCCCCEEEEEEECCEEEEEECCCCCCH
SKMAKAHGHSTTKQAADVAKEAGVNRLLLTHISARYVGPLVGQLVREAQTVHSNTFVVKD
HHHHHHCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
FYEEKIG
HHHHCCC
>Mature Secondary Structure
MEIQFLGTGAGQPSKSRNTQAIALKMLDERNEIWLFDCGEATQHQILNTTIKPRKITKIF
CEEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHCCCCCCEEEEEE
ITHLHGDHIFGLPGFLSSRSFQSSDEQTDLELYGPVGIKDFVLTALRISGSRLAYRINFH
EEEECCCEEECCCCHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCEEEEEEEHE
EIDSAGKIFEDDSFEVHTDLLDHTIFCLGYRVVEKNRIGELDANALKEAGLPFGPLFGKI
EECCCCCEECCCCCEEHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHCCCCCCHHHCCC
KKGEIVQYEGKTFDPKDYIGADKAGKIVTILGDTRKSNVAVRLAYGADLLVHEATYEANE
CCCCEEEECCCCCCCHHHCCCCCCCCEEEEEECCCCCCEEEEEEECCEEEEEECCCCCCH
SKMAKAHGHSTTKQAADVAKEAGVNRLLLTHISARYVGPLVGQLVREAQTVHSNTFVVKD
HHHHHHCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
FYEEKIG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471