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The map label for this gene is yffD

Identifier: 15672543

GI number: 15672543

Start: 555661

End: 556116

Strand: Direct

Name: yffD

Synonym: L155602

Alternate gene names: 15672543

Gene position: 555661-556116 (Clockwise)

Preceding gene: 15672541

Following gene: 15672544

Centisome position: 23.49

GC content: 32.89

Gene sequence:

>456_bases
ATGAAAGAATACAGACAAAATGTTGCAGCCATTATTCTCAATAAAGAAAACAAAATTTGGCTAGGTAAACGAGCAGATGG
GATGAGCTGGGGCTTCCCACAAGGTGGAATTGAAGCTGGTGAAAAACCAGAGACAGCCATTATTCGAGAACTCTCAGAAG
AAATTGGCACAAAAGAGTTTGAAATCATTGGACAATATCCAGGAACTTTAAAATATGATTTTCCTAAAGAGATGAAATTT
CCAACTTGGACTTATGCTGGCCAAGAACAACATTATTTTCTTGTCCGATTGCATGAAGAAGCAAAAATTAATCTTGAAAG
CCATCCTGAAGAAATTGAATTTTCAACTTATCAATTTTTAGGACTTTCTGAAATTCGTAAAATGGATTTTGGCTTTAAAA
ATGATGTTTATCATCAAGCATTAGATTATTTTTCAAAGATAATAGAAAAGAATTAA

Upstream 100 bases:

>100_bases
TTTAGCGATGAAAATGGTAAAATTGTATTAGAAGATTAATAATAAGACAAATTTTACATCTATAGAATTCAGTAAACCTA
ATACTAAAAAGAGGATAAAA

Downstream 100 bases:

>100_bases
AGGAAAAAGAATGGCTATAGAAAGAATAACAGATAATAAATTTGAACTTGTTTCAAAATATGAGCCAGCCGGTGACCAAG
GTGAGGCGATTGCTGAGTTA

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKEYRQNVAAIILNKENKIWLGKRADGMSWGFPQGGIEAGEKPETAIIRELSEEIGTKEFEIIGQYPGTLKYDFPKEMKF
PTWTYAGQEQHYFLVRLHEEAKINLESHPEEIEFSTYQFLGLSEIRKMDFGFKNDVYHQALDYFSKIIEKN

Sequences:

>Translated_151_residues
MKEYRQNVAAIILNKENKIWLGKRADGMSWGFPQGGIEAGEKPETAIIRELSEEIGTKEFEIIGQYPGTLKYDFPKEMKF
PTWTYAGQEQHYFLVRLHEEAKINLESHPEEIEFSTYQFLGLSEIRKMDFGFKNDVYHQALDYFSKIIEKN
>Mature_151_residues
MKEYRQNVAAIILNKENKIWLGKRADGMSWGFPQGGIEAGEKPETAIIRELSEEIGTKEFEIIGQYPGTLKYDFPKEMKF
PTWTYAGQEQHYFLVRLHEEAKINLESHPEEIEFSTYQFLGLSEIRKMDFGFKNDVYHQALDYFSKIIEKN

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=150, Percent_Identity=32.6666666666667, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 17720; Mature: 17720

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEYRQNVAAIILNKENKIWLGKRADGMSWGFPQGGIEAGEKPETAIIRELSEEIGTKEF
CCHHHCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEE
EIIGQYPGTLKYDFPKEMKFPTWTYAGQEQHYFLVRLHEEAKINLESHPEEIEFSTYQFL
EEEECCCCEEEECCCCCCCCCCEEECCCCCEEEEEEEECCCEECCCCCCCCCCCCHHHHH
GLSEIRKMDFGFKNDVYHQALDYFSKIIEKN
CHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEYRQNVAAIILNKENKIWLGKRADGMSWGFPQGGIEAGEKPETAIIRELSEEIGTKEF
CCHHHCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEE
EIIGQYPGTLKYDFPKEMKFPTWTYAGQEQHYFLVRLHEEAKINLESHPEEIEFSTYQFL
EEEECCCCEEEECCCCCCCCCCEEECCCCCEEEEEEEECCCEECCCCCCCCCCCCHHHHH
GLSEIRKMDFGFKNDVYHQALDYFSKIIEKN
CHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA