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The map label for this gene is def

Identifier: 15672542

GI number: 15672542

Start: 554872

End: 555507

Strand: Reverse

Name: def

Synonym: L154885

Alternate gene names: 15672542

Gene position: 555507-554872 (Counterclockwise)

Preceding gene: 15672547

Following gene: 15672540

Centisome position: 23.48

GC content: 38.21

Gene sequence:

>636_bases
ATGAATCGTGATGAAATTCAAGCAAATTTAATCAAAGCAAGTCACATGATTAGCATGGACGATATTATTCGTGAAGGTTA
TCCAACTTTACGTGAAGTGGCAAATGATGTAACCTTGCCATTGTCAGATGAAGACATTATCTTAGGAGAAAAAATGTTGC
AATTCTTACATAATTCTCAAGATCCTGTCATGGCTGAAAAAATGGGACTCCGTGGTGGAGTTGGACTTGCAGCAAACCAA
CTTGGCTTGCTCAAAAAAGTCATTGCCGTTTTGATTCCAAATGAACCTGAAGTTGATGAAGATGGAAATGAAATTCCACC
TAAAGAAGCTTACAAAATGCGCGAAATCATGTATAATGCAAAAGTGGTTAGTCACTCTGTTCAAGATGCGGCTGTTGAAG
GTGGCGAAGGTTGTCTTTCTGTTGACCGTGAAGTTCCAGGTTACGTCGTTCGCCATGCTCGTGTAACTGTGGAATACTAC
AACAAGGAAGGCGAAAAGAAAAAAATTCGCTTAAAAGATTTCCCAGCAATTTGTGTTCAACATGAGATTGATCACACTAA
TGGTGTTATGTTCTATGACCACATCAATATGAATGACCCTTGGGAAATTAAAGACGGTATGATTATTGTTAAATAA

Upstream 100 bases:

>100_bases
TCTTATTATTAATCTTCTAATACAATTTTACCATTTTCATCGCTAAAAATATGCTATAATTAATCTATATTCAAAAAAAG
ATAAGGAAGTTTTATTAATA

Downstream 100 bases:

>100_bases
TCGCCAAATTTACTGATGAATTTATGAATAGAAAAATTACTGACAGAATTTCCGTCAGTAATTTTTTATTTCATTTTCTA
CTTTTTAATTCTTGTCAGTA

Product: peptide deformylase

Products: NA

Alternate protein names: PDF; Polypeptide deformylase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MNRDEIQANLIKASHMISMDDIIREGYPTLREVANDVTLPLSDEDIILGEKMLQFLHNSQDPVMAEKMGLRGGVGLAANQ
LGLLKKVIAVLIPNEPEVDEDGNEIPPKEAYKMREIMYNAKVVSHSVQDAAVEGGEGCLSVDREVPGYVVRHARVTVEYY
NKEGEKKKIRLKDFPAICVQHEIDHTNGVMFYDHINMNDPWEIKDGMIIVK

Sequences:

>Translated_211_residues
MNRDEIQANLIKASHMISMDDIIREGYPTLREVANDVTLPLSDEDIILGEKMLQFLHNSQDPVMAEKMGLRGGVGLAANQ
LGLLKKVIAVLIPNEPEVDEDGNEIPPKEAYKMREIMYNAKVVSHSVQDAAVEGGEGCLSVDREVPGYVVRHARVTVEYY
NKEGEKKKIRLKDFPAICVQHEIDHTNGVMFYDHINMNDPWEIKDGMIIVK
>Mature_211_residues
MNRDEIQANLIKASHMISMDDIIREGYPTLREVANDVTLPLSDEDIILGEKMLQFLHNSQDPVMAEKMGLRGGVGLAANQ
LGLLKKVIAVLIPNEPEVDEDGNEIPPKEAYKMREIMYNAKVVSHSVQDAAVEGGEGCLSVDREVPGYVVRHARVTVEYY
NKEGEKKKIRLKDFPAICVQHEIDHTNGVMFYDHINMNDPWEIKDGMIIVK

Specific function: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions

COG id: COG0242

COG function: function code J; N-formylmethionyl-tRNA deformylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polypeptide deformylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000181 [H]

Pfam domain/function: PF01327 Pep_deformylase [H]

EC number: =3.5.1.88 [H]

Molecular weight: Translated: 23770; Mature: 23770

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRDEIQANLIKASHMISMDDIIREGYPTLREVANDVTLPLSDEDIILGEKMLQFLHNSQ
CCHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHCCC
DPVMAEKMGLRGGVGLAANQLGLLKKVIAVLIPNEPEVDEDGNEIPPKEAYKMREIMYNA
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KVVSHSVQDAAVEGGEGCLSVDREVPGYVVRHARVTVEYYNKEGEKKKIRLKDFPAICVQ
HHHHHHHHHHHHCCCCCCEECCCCCCCEEEHHEEEEEEEECCCCCCEEEEECCCCEEEEE
HEIDHTNGVMFYDHINMNDPWEIKDGMIIVK
EECCCCCCEEEEEECCCCCCCEECCCEEEEC
>Mature Secondary Structure
MNRDEIQANLIKASHMISMDDIIREGYPTLREVANDVTLPLSDEDIILGEKMLQFLHNSQ
CCHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHCCC
DPVMAEKMGLRGGVGLAANQLGLLKKVIAVLIPNEPEVDEDGNEIPPKEAYKMREIMYNA
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KVVSHSVQDAAVEGGEGCLSVDREVPGYVVRHARVTVEYYNKEGEKKKIRLKDFPAICVQ
HHHHHHHHHHHHCCCCCCEECCCCCCCEEEHHEEEEEEEECCCCCCEEEEECCCCEEEEE
HEIDHTNGVMFYDHINMNDPWEIKDGMIIVK
EECCCCCCEEEEEECCCCCCCEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7773380; 11337471 [H]