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The map label for this gene is fabZ1

Identifier: 15672547

GI number: 15672547

Start: 560411

End: 560866

Strand: Reverse

Name: fabZ1

Synonym: L160425

Alternate gene names: 15672547

Gene position: 560866-560411 (Counterclockwise)

Preceding gene: 15672551

Following gene: 15672542

Centisome position: 23.71

GC content: 34.87

Gene sequence:

>456_bases
ATGACTAAAAAATACGCTATGACTGCTACAGAAGTGATGGAAGTTATTCCGAACCGCTATCCTATCATGTTTATTGACTA
CGTTGATGAAATTTCTGAAAATAAAATTGTTGCAACGAAAAATGTAACGATTAACGAAGAAGTTTTTAATGGACATTTCC
CTGGTAATCCAACTTTCCCTGGTGTTTTGATTCTTGAATCACTCGCTCAAGCTGGTTCAATTTTGATTCTCAAAAAAGAA
GAATTTCAAGGAAAAATGGCTTATATTGGTGGAATTGATAAAGCAAAATTCCGTCAAAAAGTCACTCCTGGTGATGTAAT
GAAACTTGAATTTGAAATTACAAAATTCCGTGGAAAAGTAGGAACTGCTGATGCCGCAGCTTATGTTGATGGTAAAAAAG
TAACCACTTGTCAGTTCACTTTCATCGTTGATGAAGCAGCTGAACAAACAAACTAA

Upstream 100 bases:

>100_bases
TTTTAACTTAAAAATGTTGAACTGTCAAGTTAGAGTGATGGCTCTTTTTCCCTGATTACTCGGGCTTTTCATTAATTTTT
AATAAGAAAAGGAATAAAAA

Downstream 100 bases:

>100_bases
AAAAAATTTACTGACAGTCTTTGTCAGTAAATTTTTTTATTATATACAGGATTTGTCAGTAAATATCTTAACTCTCCTGC
ATTTTTTTAATAAAGGATTG

Product: hydroxymyristoyl-acyl carrier protein dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase 1

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MTKKYAMTATEVMEVIPNRYPIMFIDYVDEISENKIVATKNVTINEEVFNGHFPGNPTFPGVLILESLAQAGSILILKKE
EFQGKMAYIGGIDKAKFRQKVTPGDVMKLEFEITKFRGKVGTADAAAYVDGKKVTTCQFTFIVDEAAEQTN

Sequences:

>Translated_151_residues
MTKKYAMTATEVMEVIPNRYPIMFIDYVDEISENKIVATKNVTINEEVFNGHFPGNPTFPGVLILESLAQAGSILILKKE
EFQGKMAYIGGIDKAKFRQKVTPGDVMKLEFEITKFRGKVGTADAAAYVDGKKVTTCQFTFIVDEAAEQTN
>Mature_150_residues
TKKYAMTATEVMEVIPNRYPIMFIDYVDEISENKIVATKNVTINEEVFNGHFPGNPTFPGVLILESLAQAGSILILKKEE
FQGKMAYIGGIDKAKFRQKVTPGDVMKLEFEITKFRGKVGTADAAAYVDGKKVTTCQFTFIVDEAAEQTN

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=151, Percent_Identity=41.0596026490066, Blast_Score=115, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ1_LACLA (Q9CI03)

Other databases:

- EMBL:   AE005176
- PIR:   E86695
- RefSeq:   NP_266721.1
- ProteinModelPortal:   Q9CI03
- SMR:   Q9CI03
- GeneID:   1114184
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L160425
- NMPDR:   fig|272623.1.peg.580
- HOGENOM:   HBG433282
- OMA:   AELTFIV
- ProtClustDB:   CLSK697292
- BioCyc:   LLAC272623:L160425-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16797; Mature: 16665

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: ACT_SITE 52-52

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKYAMTATEVMEVIPNRYPIMFIDYVDEISENKIVATKNVTINEEVFNGHFPGNPTFP
CCCCHHHHHHHHHHHCCCCCCEEEEEEHHCCCCCEEEEECCCEECHHHCCCCCCCCCCCC
GVLILESLAQAGSILILKKEEFQGKMAYIGGIDKAKFRQKVTPGDVMKLEFEITKFRGKV
HHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCHHHHHHCCCCCCEEEEEEEEEEECCCC
GTADAAAYVDGKKVTTCQFTFIVDEAAEQTN
CCCCCEEEECCCEEEEEEEEEEEECCCCCCC
>Mature Secondary Structure 
TKKYAMTATEVMEVIPNRYPIMFIDYVDEISENKIVATKNVTINEEVFNGHFPGNPTFP
CCCHHHHHHHHHHHCCCCCCEEEEEEHHCCCCCEEEEECCCEECHHHCCCCCCCCCCCC
GVLILESLAQAGSILILKKEEFQGKMAYIGGIDKAKFRQKVTPGDVMKLEFEITKFRGKV
HHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCHHHHHHCCCCCCEEEEEEEEEEECCCC
GTADAAAYVDGKKVTTCQFTFIVDEAAEQTN
CCCCCEEEECCCEEEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471