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The map label for this gene is rgrA

Identifier: 15672407

GI number: 15672407

Start: 436511

End: 437227

Strand: Reverse

Name: rgrA

Synonym: L0150

Alternate gene names: 15672407

Gene position: 437227-436511 (Counterclockwise)

Preceding gene: 15672412

Following gene: 15672386

Centisome position: 18.48

GC content: 36.26

Gene sequence:

>717_bases
ATGAAGAAATATGAAGTGATTTTGCAAGATTTAGAAAAAAAGATTTTTAACGATATCTATAAAACGAACGATATTCTTCC
AAGTGAAAATGAGCTCTCTGCTAATTACGAGAGCAGTCGTTCAACAGTCAGACAGGCTTTAAAAATTTTAGAAGAGAAAG
GGCTTATTCAAAGACGACATGGCTATGGTAGCATTGTCCTCGCTCACGATAGGCTCCTTTTCCCTATCTCTGGCTTAACT
TCATACAAAGAACTACAAACCTCTATGGGTTTCCATAGTGAAACTGAGGTCATTCGATTTGAAAGACTTGAAATTAACCC
TAAACTTTCAGAAACAACTGGTTTTGCCGTTGGTGAACACGCCATAAGTATTCTCAGAAGGCGCAAAGTAGATGGCAAAT
TTTCAATTTTAGATTGGGATTTATTTTTAGAAAAATATTCCGAAGGTTTAACTCCAGAACATGCTAAAATTTCAACCTAT
GACTACTTAGAAGATACTCTAGGGCTTGATATTGCCTATGCTCAAAAGGAAGTCACGATTGATTTTGCCTGCGAAGATGA
CTTTAAATATCTTGACTTAAATCCCAAAGACCATCATGTCGTGTCTGTCAAATCTCATGTTTATCTTGCTGATAATACTC
TTTTTCAGTATACTGAATCTCGACATCAAGTCGACCGCTTTCGTTTCACAGAATTTGCCAGACGACAAAAAAGATAA

Upstream 100 bases:

>100_bases
TATCTTTTGAAGTTGTACGTACAAGTTAACAAAATCATTGTATCATATAAAAACGTTTTCAGCAAGCGGTAACAATTATT
TTTATGATAAAATATAAAGT

Downstream 100 bases:

>100_bases
AAAAGCTCTCCCAATAAGGAGAGTTTTTACTTGATAATAAAAAGCAAGAACAAAATCAGTTCTTGCTTTTTTTCTTTATT
TTACACCAATTTCTGCTTCA

Product: GntR family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKKYEVILQDLEKKIFNDIYKTNDILPSENELSANYESSRSTVRQALKILEEKGLIQRRHGYGSIVLAHDRLLFPISGLT
SYKELQTSMGFHSETEVIRFERLEINPKLSETTGFAVGEHAISILRRRKVDGKFSILDWDLFLEKYSEGLTPEHAKISTY
DYLEDTLGLDIAYAQKEVTIDFACEDDFKYLDLNPKDHHVVSVKSHVYLADNTLFQYTESRHQVDRFRFTEFARRQKR

Sequences:

>Translated_238_residues
MKKYEVILQDLEKKIFNDIYKTNDILPSENELSANYESSRSTVRQALKILEEKGLIQRRHGYGSIVLAHDRLLFPISGLT
SYKELQTSMGFHSETEVIRFERLEINPKLSETTGFAVGEHAISILRRRKVDGKFSILDWDLFLEKYSEGLTPEHAKISTY
DYLEDTLGLDIAYAQKEVTIDFACEDDFKYLDLNPKDHHVVSVKSHVYLADNTLFQYTESRHQVDRFRFTEFARRQKR
>Mature_238_residues
MKKYEVILQDLEKKIFNDIYKTNDILPSENELSANYESSRSTVRQALKILEEKGLIQRRHGYGSIVLAHDRLLFPISGLT
SYKELQTSMGFHSETEVIRFERLEINPKLSETTGFAVGEHAISILRRRKVDGKFSILDWDLFLEKYSEGLTPEHAKISTY
DYLEDTLGLDIAYAQKEVTIDFACEDDFKYLDLNPKDHHVVSVKSHVYLADNTLFQYTESRHQVDRFRFTEFARRQKR

Specific function: Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790540, Length=238, Percent_Identity=23.5294117647059, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790118, Length=169, Percent_Identity=27.2189349112426, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786950, Length=233, Percent_Identity=24.4635193133047, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR012770
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27866; Mature: 27866

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYEVILQDLEKKIFNDIYKTNDILPSENELSANYESSRSTVRQALKILEEKGLIQRRH
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHEECC
GYGSIVLAHDRLLFPISGLTSYKELQTSMGFHSETEVIRFERLEINPKLSETTGFAVGEH
CCCEEEEECCCEEEECCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHH
AISILRRRKVDGKFSILDWDLFLEKYSEGLTPEHAKISTYDYLEDTLGLDIAYAQKEVTI
HHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCCCCEECHHHHHHHHHCCEEEEECEEEEE
DFACEDDFKYLDLNPKDHHVVSVKSHVYLADNTLFQYTESRHQVDRFRFTEFARRQKR
EEEECCCCEEEECCCCCCEEEEEECEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKYEVILQDLEKKIFNDIYKTNDILPSENELSANYESSRSTVRQALKILEEKGLIQRRH
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHEECC
GYGSIVLAHDRLLFPISGLTSYKELQTSMGFHSETEVIRFERLEINPKLSETTGFAVGEH
CCCEEEEECCCEEEECCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHH
AISILRRRKVDGKFSILDWDLFLEKYSEGLTPEHAKISTYDYLEDTLGLDIAYAQKEVTI
HHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCCCCEECHHHHHHHHHCCEEEEECEEEEE
DFACEDDFKYLDLNPKDHHVVSVKSHVYLADNTLFQYTESRHQVDRFRFTEFARRQKR
EEEECCCCEEEECCCCCCEEEEEECEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9384377; 7651129; 8755887 [H]