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The map label for this gene is celA

Identifier: 15672399

GI number: 15672399

Start: 422156

End: 423592

Strand: Direct

Name: celA

Synonym: L22116

Alternate gene names: 15672399

Gene position: 422156-423592 (Clockwise)

Preceding gene: 15672398

Following gene: 15672400

Centisome position: 17.85

GC content: 36.46

Gene sequence:

>1437_bases
ATGACTTTAAAAAAAGACTTCCTCTGGGGAGGAGCAGTTGCTGCACATCAACTTGAAGGAGGATGGAATGCCGGCGGAAA
GGGAGTTTCTGTTGCTGATGTCATGACAGCAGGGAGCAATGGAGTAGAGAGAAAAATCACAGATGGGGTAATTGAGGGAG
AAAATTATCCGAATCATGAAGCTATTGATTTTTATCATCGCTACAAAGAAGATATTGCACTCTTTGATGAATTGGGATTA
AATTGTTTTAGAACTTCCATTGCATGGACTCGTATTTTTCCAAATGGAGATGAAGCGGAACCTAATGAAGAAGGTTTGCA
ATTCTATGATGATTTATTTGATGAGTGTTTAAAACATGGGATTGAACCTGTAATTACTCTATCTCACTTTGAACTTCCTT
ATCACTTAGTGACAGAATATGGTGGCTTTCGTAATCGTAAACTCATTGATTTCTTTGTCCATTTTTCAGAAGTCGTAATG
AATCGTTATAAAGATAAAGTTAAATATTGGATGACTTTCAATGAAATCAACAACCAAGCAAACTATTTGCGTGATTTTGC
ACCATTTACTAATTCTGGTTTAAAATTCCCAGAAGGAGCAAGCGAAAAAGAACGTGAAGAAATGATGTATCAAGCGGCTC
ATTATGAGTTGGTTGCTTCTGCCAAAGTTGTCGCTCTGGGACATAAAATCAATCCAGATTTCCAAATTGGATGTATGATT
GCCATGTGTCCGATTTATCCTGCAACTTGTAAACCAGAAGATATGATGGCTTCAACCGTTGCTATGCAACGTCGCTATTG
GTTTGCAGATGTTCATGTTCGCGGACATTACCCAAGCTATTTAAAAGCCTATTTTGACCGTAAGGAATTTAAACTTGATA
TTCTTGATGATGATTTGAAAGCATTGGAAGAAGGAAAAGTAGATTATATTGGTTTTTCTTACTACATGAGTTTTGCAATT
AAAGACCATGGTAAAGCTCCTACTTTTGATTACAATGAAGATAAAGATTTAGTCAAAAATGAATATGTTAAAGCTTCTGA
ATGGGGCTGGCAAATTGATCCTTTAGGATTACGTTATGCAATGAATTGGTTCTATGAACGTTATGAAAAACCACTCTTCA
TTGTTGAAAATGGTTTTGGTGCTGTAGATGAAGTTGAAGCTGACGGAAGTATTCATGACCCTTATCGAGTAGATTATTTA
AAAGCTCATATAGAAGCAATGAAAAATGCTGTAGATTATGATGGAGTTGACTTAATGGGTTATACTCCGTGGGGCTTTAT
TGACCTTGTTTCTGCTGGGACAGGTGAGATGAAAAAACGCTATGGCGTCATATATGTAGATAAGGATAACGAAGGAAATG
GGACATTAGAACGTTCGAAAAAAGACTCCTTTACTTGGTATCAAAAAGTTATCGCAACAAATGGTGAAGAACTTTAA

Upstream 100 bases:

>100_bases
AATTAATGCTGCTGAATAATAGCAAATTTTAGATGAGCTCAAGAATTCTTGAGCTTATCTTATTAAAAATGTTAATTCTA
AAAATTTAAAAGGAGAAATT

Downstream 100 bases:

>100_bases
AAATAAAAGACACGAAAGTGTCTTTTTATTTTTATTGGAATGTAAAGAAAACACTCCAAAAGTGGAAAAAGTAGTATAAA
GGGTACGTAACTATATTTTA

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MTLKKDFLWGGAVAAHQLEGGWNAGGKGVSVADVMTAGSNGVERKITDGVIEGENYPNHEAIDFYHRYKEDIALFDELGL
NCFRTSIAWTRIFPNGDEAEPNEEGLQFYDDLFDECLKHGIEPVITLSHFELPYHLVTEYGGFRNRKLIDFFVHFSEVVM
NRYKDKVKYWMTFNEINNQANYLRDFAPFTNSGLKFPEGASEKEREEMMYQAAHYELVASAKVVALGHKINPDFQIGCMI
AMCPIYPATCKPEDMMASTVAMQRRYWFADVHVRGHYPSYLKAYFDRKEFKLDILDDDLKALEEGKVDYIGFSYYMSFAI
KDHGKAPTFDYNEDKDLVKNEYVKASEWGWQIDPLGLRYAMNWFYERYEKPLFIVENGFGAVDEVEADGSIHDPYRVDYL
KAHIEAMKNAVDYDGVDLMGYTPWGFIDLVSAGTGEMKKRYGVIYVDKDNEGNGTLERSKKDSFTWYQKVIATNGEEL

Sequences:

>Translated_478_residues
MTLKKDFLWGGAVAAHQLEGGWNAGGKGVSVADVMTAGSNGVERKITDGVIEGENYPNHEAIDFYHRYKEDIALFDELGL
NCFRTSIAWTRIFPNGDEAEPNEEGLQFYDDLFDECLKHGIEPVITLSHFELPYHLVTEYGGFRNRKLIDFFVHFSEVVM
NRYKDKVKYWMTFNEINNQANYLRDFAPFTNSGLKFPEGASEKEREEMMYQAAHYELVASAKVVALGHKINPDFQIGCMI
AMCPIYPATCKPEDMMASTVAMQRRYWFADVHVRGHYPSYLKAYFDRKEFKLDILDDDLKALEEGKVDYIGFSYYMSFAI
KDHGKAPTFDYNEDKDLVKNEYVKASEWGWQIDPLGLRYAMNWFYERYEKPLFIVENGFGAVDEVEADGSIHDPYRVDYL
KAHIEAMKNAVDYDGVDLMGYTPWGFIDLVSAGTGEMKKRYGVIYVDKDNEGNGTLERSKKDSFTWYQKVIATNGEEL
>Mature_477_residues
TLKKDFLWGGAVAAHQLEGGWNAGGKGVSVADVMTAGSNGVERKITDGVIEGENYPNHEAIDFYHRYKEDIALFDELGLN
CFRTSIAWTRIFPNGDEAEPNEEGLQFYDDLFDECLKHGIEPVITLSHFELPYHLVTEYGGFRNRKLIDFFVHFSEVVMN
RYKDKVKYWMTFNEINNQANYLRDFAPFTNSGLKFPEGASEKEREEMMYQAAHYELVASAKVVALGHKINPDFQIGCMIA
MCPIYPATCKPEDMMASTVAMQRRYWFADVHVRGHYPSYLKAYFDRKEFKLDILDDDLKALEEGKVDYIGFSYYMSFAIK
DHGKAPTFDYNEDKDLVKNEYVKASEWGWQIDPLGLRYAMNWFYERYEKPLFIVENGFGAVDEVEADGSIHDPYRVDYLK
AHIEAMKNAVDYDGVDLMGYTPWGFIDLVSAGTGEMKKRYGVIYVDKDNEGNGTLERSKKDSFTWYQKVIATNGEEL

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=499, Percent_Identity=29.4589178356713, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI32481206, Length=495, Percent_Identity=29.6969696969697, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI13273313, Length=494, Percent_Identity=26.1133603238866, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI24497614, Length=491, Percent_Identity=28.7169042769857, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI28376633, Length=490, Percent_Identity=28.7755102040816, Blast_Score=147, Evalue=3e-35,
Organism=Escherichia coli, GI2367174, Length=478, Percent_Identity=60.6694560669456, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI1789070, Length=480, Percent_Identity=48.75, Blast_Score=476, Evalue=1e-135,
Organism=Escherichia coli, GI2367270, Length=472, Percent_Identity=48.728813559322, Blast_Score=459, Evalue=1e-130,
Organism=Caenorhabditis elegans, GI17552856, Length=482, Percent_Identity=28.6307053941909, Blast_Score=171, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17539390, Length=487, Percent_Identity=27.9260780287474, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI21356577, Length=500, Percent_Identity=28, Blast_Score=157, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 55011; Mature: 54880

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKKDFLWGGAVAAHQLEGGWNAGGKGVSVADVMTAGSNGVERKITDGVIEGENYPNHE
CCCCCCCCCCCCHHHHEECCCCCCCCCCCCHHHHHCCCCCCCCHHHHCCEECCCCCCCCH
AIDFYHRYKEDIALFDELGLNCFRTSIAWTRIFPNGDEAEPNEEGLQFYDDLFDECLKHG
HHHHHHHHHHHHHHHHHHCCHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
IEPVITLSHFELPYHLVTEYGGFRNRKLIDFFVHFSEVVMNRYKDKVKYWMTFNEINNQA
CCEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHCCHH
NYLRDFAPFTNSGLKFPEGASEKEREEMMYQAAHYELVASAKVVALGHKINPDFQIGCMI
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEE
AMCPIYPATCKPEDMMASTVAMQRRYWFADVHVRGHYPSYLKAYFDRKEFKLDILDDDLK
EECCCCCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHCCCCEEEEECCHHHH
ALEEGKVDYIGFSYYMSFAIKDHGKAPTFDYNEDKDLVKNEYVKASEWGWQIDPLGLRYA
HHHCCCEEEEEHHHEEEEEEECCCCCCCCCCCCCHHHHHHHCEECCCCCCEECCHHHHHH
MNWFYERYEKPLFIVENGFGAVDEVEADGSIHDPYRVDYLKAHIEAMKNAVDYDGVDLMG
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEC
YTPWGFIDLVSAGTGEMKKRYGVIYVDKDNEGNGTLERSKKDSFTWYQKVIATNGEEL
CCCCCHHHHHCCCCCHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TLKKDFLWGGAVAAHQLEGGWNAGGKGVSVADVMTAGSNGVERKITDGVIEGENYPNHE
CCCCCCCCCCCHHHHEECCCCCCCCCCCCHHHHHCCCCCCCCHHHHCCEECCCCCCCCH
AIDFYHRYKEDIALFDELGLNCFRTSIAWTRIFPNGDEAEPNEEGLQFYDDLFDECLKHG
HHHHHHHHHHHHHHHHHHCCHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
IEPVITLSHFELPYHLVTEYGGFRNRKLIDFFVHFSEVVMNRYKDKVKYWMTFNEINNQA
CCEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHCCHH
NYLRDFAPFTNSGLKFPEGASEKEREEMMYQAAHYELVASAKVVALGHKINPDFQIGCMI
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEE
AMCPIYPATCKPEDMMASTVAMQRRYWFADVHVRGHYPSYLKAYFDRKEFKLDILDDDLK
EECCCCCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHCCCCEEEEECCHHHH
ALEEGKVDYIGFSYYMSFAIKDHGKAPTFDYNEDKDLVKNEYVKASEWGWQIDPLGLRYA
HHHCCCEEEEEHHHEEEEEEECCCCCCCCCCCCCHHHHHHHCEECCCCCCEECCHHHHHH
MNWFYERYEKPLFIVENGFGAVDEVEADGSIHDPYRVDYLKAHIEAMKNAVDYDGVDLMG
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEC
YTPWGFIDLVSAGTGEMKKRYGVIYVDKDNEGNGTLERSKKDSFTWYQKVIATNGEEL
CCCCCHHHHHCCCCCHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8125345; 9384377 [H]