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The map label for this gene is ahpF

Identifier: 15672320

GI number: 15672320

Start: 336014

End: 337543

Strand: Direct

Name: ahpF

Synonym: L135954

Alternate gene names: 15672320

Gene position: 336014-337543 (Clockwise)

Preceding gene: 15672319

Following gene: 15672321

Centisome position: 14.2

GC content: 38.56

Gene sequence:

>1530_bases
ATGATTTTAGATGAAACTCTTCGTGCTCAGTTGATGCCTTATATGGATTTGTTGGAAAATCCAATTATTTTAAAAGTTGA
TGCAGATTTAGAGAGCGAAAATGGGAAAAAAATAGTAGAATTTACAGATGAACTTGCAAGTTTGTCCGAAATGATTTCAA
AAGAAACAGCAAAACTCAATCGAAAAACAGCTTTCTCTATTGAAAGAGAAGGTGTTTCTGGAGTCCTTTTTTCAGGGCTA
CCATTAGGTCATGAGTTGAATTCATTGGTCTTGGCGCTTGTCCAAGTAAGTGGACGCCCTCCACGGATTGAACAAGAATT
AGTTGAGCGAATTCAAGCGATTCAAAATCCACTTCACTTTGAAACTTATGTGAGTTTAACTTGTCATAACTGTCCAGATG
TTGTCCAAGCATTAAACACAATGAGTATTCTCAACCCCAATATTAGTCACACAATGATTGAGGGGGGAATGTTTCAAGAA
GAAGTGGAAGCAAAAGGAATTATGGCGGTTCCAACTGTTTTCAAAAATGGTGAAGAATTTCATAATGGACGAGCTAGTCT
TGAAGAATTACTAGAAAAAATTACTGGTCCAGAGAGTTCGGAAGCTTTTTTTGATAAAGACCCTTATGATGTTTTAGTTG
TTGGTGGAGGCCCTGCTGGTGCAAGTGCAGCTATTTATGCTGCACGTAAAGGGATTCGGACAGGTTTAATCGCTGAACGC
TTTGGCGGTCAACCACTAGAAACTTTAGGAATTGAAAACCTCATTGGAACTCCTTATGTTGAAGGAGTTCAACTTGGTCG
TCAGCTTGAAGAACATGTGAAAAAATATCCTGTCGATTTGATGAACTTGCAAAAAGCAGTTAAGCTAGAGAAAAAAGATT
TGATTGAGGTGAGTCTTGAAAATGGGGCACTTCTAAAAAGTAAGTCAGTCATTATTTCAACGGGCGCTCGTTGGCGAGAT
TTGGGAATTCCAGGAGAGCAAGAATTTAAAACCAAAGGAGTCGCTTACTGTCCACATTGTGATGGTCCTTTGTTTGCAGG
AAAAGATGTAGCGGTTATCGGTGGCGGAAATTCAGGAATCGAAGCAGCTATTGATTTAGCTGGTTTGGTTAGACATGTTA
CTGTTCTTGAATTTTTACCTGAACTTAAAGCAGACAAAATTTTACAAGAAAAACTTGCGACCCTAAATAATGTTACTGTC
CTCACCAATGTAGAAACAAAAGAGATTTTAGGAGATGACAAGGTTAGAGGTTTGAATTATCAAGTTCGCGGCTCTAAAGA
AACTGTTCATTTGGAACTTGCTGGTGTCTTTGTATTAATTGGTTTAGTTCCGAATACTCAGTGGTTGGAGGGAACAATTG
ACTTATCCGCACGTGGAGAAATTTTGACTGATAAAGTTGGAGCGACAAATCTTCCTGGTGTTTTTGCAGCGGGAGATTGT
ACGGATAGTGTTTATAAGCAAATTATTATTTCAATGGGGACTGGGGCGACCGCTTCTCTAGGTGCTTTTGATTATTTAAT
AAGAAACTAA

Upstream 100 bases:

>100_bases
TCACGTTGGTATTGACCTTGTAGGTAAAATATAGAATAAAAAAAGTGAGTCTTGGCTCACTTTATTTGTCTTTAGAAACT
TAATGACAGAAAGGTTTAAT

Downstream 100 bases:

>100_bases
AATTTTAGATGACAAAAAAGAAAACGTATTTGAGTTTTCTTTTTTTATTTGATTAAATTGATAGGAATCAAAATTGTAAG
GAAAAGTTTTCATAAATGTG

Product: alkyl hydroperoxide reductase

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MILDETLRAQLMPYMDLLENPIILKVDADLESENGKKIVEFTDELASLSEMISKETAKLNRKTAFSIEREGVSGVLFSGL
PLGHELNSLVLALVQVSGRPPRIEQELVERIQAIQNPLHFETYVSLTCHNCPDVVQALNTMSILNPNISHTMIEGGMFQE
EVEAKGIMAVPTVFKNGEEFHNGRASLEELLEKITGPESSEAFFDKDPYDVLVVGGGPAGASAAIYAARKGIRTGLIAER
FGGQPLETLGIENLIGTPYVEGVQLGRQLEEHVKKYPVDLMNLQKAVKLEKKDLIEVSLENGALLKSKSVIISTGARWRD
LGIPGEQEFKTKGVAYCPHCDGPLFAGKDVAVIGGGNSGIEAAIDLAGLVRHVTVLEFLPELKADKILQEKLATLNNVTV
LTNVETKEILGDDKVRGLNYQVRGSKETVHLELAGVFVLIGLVPNTQWLEGTIDLSARGEILTDKVGATNLPGVFAAGDC
TDSVYKQIIISMGTGATASLGAFDYLIRN

Sequences:

>Translated_509_residues
MILDETLRAQLMPYMDLLENPIILKVDADLESENGKKIVEFTDELASLSEMISKETAKLNRKTAFSIEREGVSGVLFSGL
PLGHELNSLVLALVQVSGRPPRIEQELVERIQAIQNPLHFETYVSLTCHNCPDVVQALNTMSILNPNISHTMIEGGMFQE
EVEAKGIMAVPTVFKNGEEFHNGRASLEELLEKITGPESSEAFFDKDPYDVLVVGGGPAGASAAIYAARKGIRTGLIAER
FGGQPLETLGIENLIGTPYVEGVQLGRQLEEHVKKYPVDLMNLQKAVKLEKKDLIEVSLENGALLKSKSVIISTGARWRD
LGIPGEQEFKTKGVAYCPHCDGPLFAGKDVAVIGGGNSGIEAAIDLAGLVRHVTVLEFLPELKADKILQEKLATLNNVTV
LTNVETKEILGDDKVRGLNYQVRGSKETVHLELAGVFVLIGLVPNTQWLEGTIDLSARGEILTDKVGATNLPGVFAAGDC
TDSVYKQIIISMGTGATASLGAFDYLIRN
>Mature_509_residues
MILDETLRAQLMPYMDLLENPIILKVDADLESENGKKIVEFTDELASLSEMISKETAKLNRKTAFSIEREGVSGVLFSGL
PLGHELNSLVLALVQVSGRPPRIEQELVERIQAIQNPLHFETYVSLTCHNCPDVVQALNTMSILNPNISHTMIEGGMFQE
EVEAKGIMAVPTVFKNGEEFHNGRASLEELLEKITGPESSEAFFDKDPYDVLVVGGGPAGASAAIYAARKGIRTGLIAER
FGGQPLETLGIENLIGTPYVEGVQLGRQLEEHVKKYPVDLMNLQKAVKLEKKDLIEVSLENGALLKSKSVIISTGARWRD
LGIPGEQEFKTKGVAYCPHCDGPLFAGKDVAVIGGGNSGIEAAIDLAGLVRHVTVLEFLPELKADKILQEKLATLNNVTV
LTNVETKEILGDDKVRGLNYQVRGSKETVHLELAGVFVLIGLVPNTQWLEGTIDLSARGEILTDKVGATNLPGVFAAGDC
TDSVYKQIIISMGTGATASLGAFDYLIRN

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone [H]

COG id: COG3634

COG function: function code O; Alkyl hydroperoxide reductase, large subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081763, Length=518, Percent_Identity=53.4749034749035, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI1787114, Length=309, Percent_Identity=36.2459546925566, Blast_Score=161, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=32.9073482428115, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=310, Percent_Identity=33.8709677419355, Blast_Score=140, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012081
- InterPro:   IPR013027
- InterPro:   IPR002109
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 55143; Mature: 55143

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILDETLRAQLMPYMDLLENPIILKVDADLESENGKKIVEFTDELASLSEMISKETAKLN
CCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RKTAFSIEREGVSGVLFSGLPLGHELNSLVLALVQVSGRPPRIEQELVERIQAIQNPLHF
CHHEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCE
ETYVSLTCHNCPDVVQALNTMSILNPNISHTMIEGGMFQEEVEAKGIMAVPTVFKNGEEF
EEEEEEEECCCHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHCCCEEEECHHHCCCHHH
HNGRASLEELLEKITGPESSEAFFDKDPYDVLVVGGGPAGASAAIYAARKGIRTGLIAER
HCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHH
FGGQPLETLGIENLIGTPYVEGVQLGRQLEEHVKKYPVDLMNLQKAVKLEKKDLIEVSLE
HCCCCHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHEEEEEEC
NGALLKSKSVIISTGARWRDLGIPGEQEFKTKGVAYCPHCDGPLFAGKDVAVIGGGNSGI
CCCEEECCCEEEECCCCEEECCCCCCHHHCCCCEEECCCCCCCEECCCCEEEEECCCCCH
EAAIDLAGLVRHVTVLEFLPELKADKILQEKLATLNNVTVLTNVETKEILGDDKVRGLNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCCCCCCCCCE
QVRGSKETVHLELAGVFVLIGLVPNTQWLEGTIDLSARGEILTDKVGATNLPGVFAAGDC
EEECCCCEEEEEHEEEEEEEEECCCCCEEEEEEEECCCCCEEECCCCCCCCCCEEECCCC
TDSVYKQIIISMGTGATASLGAFDYLIRN
HHHHHHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MILDETLRAQLMPYMDLLENPIILKVDADLESENGKKIVEFTDELASLSEMISKETAKLN
CCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RKTAFSIEREGVSGVLFSGLPLGHELNSLVLALVQVSGRPPRIEQELVERIQAIQNPLHF
CHHEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCE
ETYVSLTCHNCPDVVQALNTMSILNPNISHTMIEGGMFQEEVEAKGIMAVPTVFKNGEEF
EEEEEEEECCCHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHCCCEEEECHHHCCCHHH
HNGRASLEELLEKITGPESSEAFFDKDPYDVLVVGGGPAGASAAIYAARKGIRTGLIAER
HCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHH
FGGQPLETLGIENLIGTPYVEGVQLGRQLEEHVKKYPVDLMNLQKAVKLEKKDLIEVSLE
HCCCCHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHEEEEEEC
NGALLKSKSVIISTGARWRDLGIPGEQEFKTKGVAYCPHCDGPLFAGKDVAVIGGGNSGI
CCCEEECCCEEEECCCCEEECCCCCCHHHCCCCEEECCCCCCCEECCCCEEEEECCCCCH
EAAIDLAGLVRHVTVLEFLPELKADKILQEKLATLNNVTVLTNVETKEILGDDKVRGLNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCCCCCCCCCE
QVRGSKETVHLELAGVFVLIGLVPNTQWLEGTIDLSARGEILTDKVGATNLPGVFAAGDC
EEECCCCEEEEEHEEEEEEEEECCCCCEEEEEEEECCCCCEEECCCCCCCCCCEEECCCC
TDSVYKQIIISMGTGATASLGAFDYLIRN
HHHHHHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1917890; 2760020 [H]