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The map label for this gene is fhuG

Identifier: 15672311

GI number: 15672311

Start: 328424

End: 329362

Strand: Direct

Name: fhuG

Synonym: L128386

Alternate gene names: 15672311

Gene position: 328424-329362 (Clockwise)

Preceding gene: 15672310

Following gene: 15672312

Centisome position: 13.88

GC content: 34.72

Gene sequence:

>939_bases
ATGAAAAGAAAATTCACTTTACTTTTTGTCCTGCTTTTGGTTTTGATAGTGGTTGATTTGACGCAATTTTCAACAAATCC
TCAAATTCTATCAATCCTAATTCCTAATTTTCGTCTTCCTCGTTTAATAACAATCCTGTCAGCTGGAATTGCTCTTTCCT
TATCAGGCTTTATTATCCAAAATATTACAGAAAATCCTTTAGCTGATAGTGGAACAATTGGGATAACCTCTGGTGCTTCG
GCAGGAAGTGTTGCTTTTTTACTGATTGCTGACCATTTTAAGCTGACAGGACTTTGGAATTTTTCCTATCCTATTTTTGC
TTTAATAGGTGCTCTTCTTTCATTTGTCTTAATTTACTTTTTTGCCTTAAGAAAGCAAGTTTCTTCTGTCAGAGTTTTAC
TGACAGGAATTGCAATTACCGCTTTTTTCCAAGCATTAATCACAATTGGTCAGCTTTCAGTCAATGCCTTTGACTTTCAG
AAAGTTGCAGTTTGGCTGTCAGGAGATATCTGGCAAACGGGAAGCACTTATTTGTTCATTTGTGTTCTCTTATTAGTAAT
TGGCTTGATTATTTTGCCATTTTTCTTAAGAAAACTTGAAATCCTCTCACTTGGCGAAGAAATGGCAACTACTTTAGGAT
TAGAAGTTCAAAAAACGAAAATCTATCTTTACTTGTTAGCACTCCTTTTTGCAGCTGTCGGTGTTTTATTGGTTGGAGGA
TTAGCATTTGTTGGTTTAATTGCCCCTCATATTGCTCGTGAAATCGCTGGTTTTAAATCACGAAAAAGTTTAATTGCCAC
CGCGCTTTCTGGTATGATTATTTTATCTTTTGCTGATATTATTTCACAAACAATCATTGCACCATCAAGTTTACCTTTAG
GTTTTGTAGTTGCCTTTATTGGCGCTCCATACTATATTTATCTTATTCAAAAAGTTTAA

Upstream 100 bases:

>100_bases
AGAAATTTATTTAAACCTTACGAATTTCCAGCAGGAAGTCTAACCATGCTTCTAGGTGCTCCCTTCTTTCTTTGGGTTAT
TACAAAGGAGGCAAAATAGA

Downstream 100 bases:

>100_bases
GAAATTAATTTACTTTTAGTAAATTTCTTATAAAAAAATATCGGCTTATTTTTAAAAAATAGCCTAAAAATAGAGGAGAA
TCTTTTGAAAAAAGTACTCA

Product: ferrichrome ABC transporter permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKRKFTLLFVLLLVLIVVDLTQFSTNPQILSILIPNFRLPRLITILSAGIALSLSGFIIQNITENPLADSGTIGITSGAS
AGSVAFLLIADHFKLTGLWNFSYPIFALIGALLSFVLIYFFALRKQVSSVRVLLTGIAITAFFQALITIGQLSVNAFDFQ
KVAVWLSGDIWQTGSTYLFICVLLLVIGLIILPFFLRKLEILSLGEEMATTLGLEVQKTKIYLYLLALLFAAVGVLLVGG
LAFVGLIAPHIAREIAGFKSRKSLIATALSGMIILSFADIISQTIIAPSSLPLGFVVAFIGAPYYIYLIQKV

Sequences:

>Translated_312_residues
MKRKFTLLFVLLLVLIVVDLTQFSTNPQILSILIPNFRLPRLITILSAGIALSLSGFIIQNITENPLADSGTIGITSGAS
AGSVAFLLIADHFKLTGLWNFSYPIFALIGALLSFVLIYFFALRKQVSSVRVLLTGIAITAFFQALITIGQLSVNAFDFQ
KVAVWLSGDIWQTGSTYLFICVLLLVIGLIILPFFLRKLEILSLGEEMATTLGLEVQKTKIYLYLLALLFAAVGVLLVGG
LAFVGLIAPHIAREIAGFKSRKSLIATALSGMIILSFADIISQTIIAPSSLPLGFVVAFIGAPYYIYLIQKV
>Mature_312_residues
MKRKFTLLFVLLLVLIVVDLTQFSTNPQILSILIPNFRLPRLITILSAGIALSLSGFIIQNITENPLADSGTIGITSGAS
AGSVAFLLIADHFKLTGLWNFSYPIFALIGALLSFVLIYFFALRKQVSSVRVLLTGIAITAFFQALITIGQLSVNAFDFQ
KVAVWLSGDIWQTGSTYLFICVLLLVIGLIILPFFLRKLEILSLGEEMATTLGLEVQKTKIYLYLLALLFAAVGVLLVGG
LAFVGLIAPHIAREIAGFKSRKSLIATALSGMIILSFADIISQTIIAPSSLPLGFVVAFIGAPYYIYLIQKV

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=293, Percent_Identity=32.7645051194539, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1786347, Length=325, Percent_Identity=34.4615384615385, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1790741, Length=296, Percent_Identity=28.0405405405405, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786805, Length=286, Percent_Identity=34.965034965035, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1788004, Length=280, Percent_Identity=32.5, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786804, Length=288, Percent_Identity=29.1666666666667, Blast_Score=105, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 33850; Mature: 33850

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKFTLLFVLLLVLIVVDLTQFSTNPQILSILIPNFRLPRLITILSAGIALSLSGFIIQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
NITENPLADSGTIGITSGASAGSVAFLLIADHFKLTGLWNFSYPIFALIGALLSFVLIYF
CCCCCCCCCCCCEEEECCCCCCCEEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHH
FALRKQVSSVRVLLTGIAITAFFQALITIGQLSVNAFDFQKVAVWLSGDIWQTGSTYLFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEECCCCCCCCHHHHH
CVLLLVIGLIILPFFLRKLEILSLGEEMATTLGLEVQKTKIYLYLLALLFAAVGVLLVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAFVGLIAPHIAREIAGFKSRKSLIATALSGMIILSFADIISQTIIAPSSLPLGFVVAFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GAPYYIYLIQKV
CCCEEEEEEECC
>Mature Secondary Structure
MKRKFTLLFVLLLVLIVVDLTQFSTNPQILSILIPNFRLPRLITILSAGIALSLSGFIIQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
NITENPLADSGTIGITSGASAGSVAFLLIADHFKLTGLWNFSYPIFALIGALLSFVLIYF
CCCCCCCCCCCCEEEECCCCCCCEEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHH
FALRKQVSSVRVLLTGIAITAFFQALITIGQLSVNAFDFQKVAVWLSGDIWQTGSTYLFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEECCCCCCCCHHHHH
CVLLLVIGLIILPFFLRKLEILSLGEEMATTLGLEVQKTKIYLYLLALLFAAVGVLLVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAFVGLIAPHIAREIAGFKSRKSLIATALSGMIILSFADIISQTIIAPSSLPLGFVVAFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GAPYYIYLIQKV
CCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]