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The map label for this gene is ycgE

Identifier: 15672248

GI number: 15672248

Start: 265021

End: 265497

Strand: Reverse

Name: ycgE

Synonym: L65029

Alternate gene names: 15672248

Gene position: 265497-265021 (Counterclockwise)

Preceding gene: 15672254

Following gene: 30023985

Centisome position: 11.22

GC content: 38.78

Gene sequence:

>477_bases
ATGGCTGAAGTAGAATCTTTTCAATTAGACCACACAAAAGTACTTGCCCCTTATGTCCGCTTAATCGGTAGCGAAACTGG
GCCTAAAGGCGATGTTATCACTAATTTTGACGTTCGTTTTGTTCAACCTAATGCGAATGCCATTGGAATGGCCGCTTTAC
ACACTATTGAGCATAGCATGGCTAGTTTAATTCGCGATAGAATTGATGGCATGATTGACTTTTCACCTTTTGGATGTCAA
ACTGGTTTCCACATGATTATGTGGGGTGAACATAGTTCAGAAGAAATTGCTAAAGTAATTAAATCTTCTCTAGAAGAGCT
TGCAAGTGACGAATTTGGTTGGGATAATGTCCCTGGTGTTGCTGAAAAAGAATGCGGAAATTACCGTAATCACTCACTTT
TCGGTGCTAAAGAATGGTCTAAGAAAATTCTTTCTGAAGGAATTTCTACTGACCCTTACGAACGTAAAGTAATTTAA

Upstream 100 bases:

>100_bases
TTTCGCTCAAAAAATGATAGAATAGAATTAGAATTTAAAATAAAGGAGGAGATACTAATAAGGCTGACTTTTATCAGCTG
AGTTTTGTATCCTATATCTT

Downstream 100 bases:

>100_bases
AGTTCAGCATTTTTAAATTACAAGTGCAACTTCATTTCCTTTAGTAAGGAATTTAATCGGTCAAATTTTTACTGACAGCT
CTTGTCAGTAACTTTTTGAC

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MAEVESFQLDHTKVLAPYVRLIGSETGPKGDVITNFDVRFVQPNANAIGMAALHTIEHSMASLIRDRIDGMIDFSPFGCQ
TGFHMIMWGEHSSEEIAKVIKSSLEELASDEFGWDNVPGVAEKECGNYRNHSLFGAKEWSKKILSEGISTDPYERKVI

Sequences:

>Translated_158_residues
MAEVESFQLDHTKVLAPYVRLIGSETGPKGDVITNFDVRFVQPNANAIGMAALHTIEHSMASLIRDRIDGMIDFSPFGCQ
TGFHMIMWGEHSSEEIAKVIKSSLEELASDEFGWDNVPGVAEKECGNYRNHSLFGAKEWSKKILSEGISTDPYERKVI
>Mature_157_residues
AEVESFQLDHTKVLAPYVRLIGSETGPKGDVITNFDVRFVQPNANAIGMAALHTIEHSMASLIRDRIDGMIDFSPFGCQT
GFHMIMWGEHSSEEIAKVIKSSLEELASDEFGWDNVPGVAEKECGNYRNHSLFGAKEWSKKILSEGISTDPYERKVI

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=158, Percent_Identity=33.5443037974684, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_LACLA (Q9CIU0)

Other databases:

- EMBL:   AE005176
- PIR:   B86658
- RefSeq:   NP_266422.1
- ProteinModelPortal:   Q9CIU0
- SMR:   Q9CIU0
- GeneID:   1113876
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L65029
- NMPDR:   fig|272623.1.peg.274
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- ProtClustDB:   PRK02260
- BioCyc:   LLAC272623:L65029-MONOMER
- BRENDA:   4.4.1.21
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 17605; Mature: 17474

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVESFQLDHTKVLAPYVRLIGSETGPKGDVITNFDVRFVQPNANAIGMAALHTIEHSM
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCEEEEECCCCCCHHHHHHHHHHHHH
ASLIRDRIDGMIDFSPFGCQTGFHMIMWGEHSSEEIAKVIKSSLEELASDEFGWDNVPGV
HHHHHHHHCCEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
AEKECGNYRNHSLFGAKEWSKKILSEGISTDPYERKVI
CHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AEVESFQLDHTKVLAPYVRLIGSETGPKGDVITNFDVRFVQPNANAIGMAALHTIEHSM
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCEEEEECCCCCCHHHHHHHHHHHHH
ASLIRDRIDGMIDFSPFGCQTGFHMIMWGEHSSEEIAKVIKSSLEELASDEFGWDNVPGV
HHHHHHHHCCEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
AEKECGNYRNHSLFGAKEWSKKILSEGISTDPYERKVI
CHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471