Click here to switch to the map view.

The map label for this gene is rnhB-1

Identifier: 161579047

GI number: 161579047

Start: 330423

End: 331322

Strand: Reverse

Name: rnhB-1

Synonym: TC0276

Alternate gene names: 161579047

Gene position: 331322-330423 (Counterclockwise)

Preceding gene: 15834898

Following gene: 15834894

Centisome position: 30.88

GC content: 40.0

Gene sequence:

>900_bases
ATGCCCACCCCTTTCGTCTCGCAACTTTCTCCTTCTCTATTCACAACTCTTAGGGAACAGTTAGAGAAAAAAGGGTTTGT
GATTTCTATCCCTCCTCATACTGTTTTTCAAGGAAGATCTTCTACCGTAAGCTGCACTGTATATCAATCTGGGAAAATAG
TGGTACAAGGAAAGGGAACTCAAGAATTTGTTGAATTTTTCCTTGAACCCGAAATTTTACACTCCTTTTCTATACAAAAT
GTGCAACAGGATTTACGTCCACGCATAGGCGTGGACGAATCTGGAAAAGGAGATTTCTTTGGCCCCCTTTGTACAGCTGG
AGTCTATGCTCCTTCTATAAAATCTATAGAATCTCTTTACGAAATAACCATTTGTGATTCTAAACTTATCTCCGATGCTA
AGATCCCCTCTCTAGCTCGTAGTATCCGCTCGCTTTGTACTTGTAAGGTCATTACTTTATTCCCAGAAAAATATAATGCT
CTATACGCTAATTTTCAGAACCTAAATGCTCTCCTCGCTTGGACGCACGCGACTATTATTGATGATTTGGCTCCTAAACC
TACTGGGGACGTCTTTGCTATTTCAGATCAATTTGCTTCTTCCGAAAGAGTCCTTTTGCAAGCTGTCCGAAAAAAACGAG
CAGATATTGAATTAATTCAGCGTCACCGTGCAGAACAAGATGTTGTAGTAGCTGCAGCTTCTATCTTAGCTCGAGATGCT
TTTCTCTCTTCTATGCAAACACTAGAATCTCAGTATCAAGTCCGGCTACTCAAGGGAGCTTCAGGGAAAGTTAAACAGCA
AGCAAAAGAGATTCTTCGCGACAAAGGACAACCTGTTCTAGAAAAGGTTTGCAAAACACATTTTAAAACATTTTATGAAG
TACTTGGTTCAACTTCTTAA

Upstream 100 bases:

>100_bases
GAAAAATTTTTCGATCATAAAGATTTAAGGGTGATAGAATGGGGAGAGAAATCCTTAATTGTGGTTTCTTTCTTGAAAAG
ATAATTTTTTTAGGATGATT

Downstream 100 bases:

>100_bases
CAGAAGCATCCCGTATTTTTAAAAGTGTAGATTTGCAGAGCCTCCAAAAAATAGCGAAGAACCAAACTTATATATCTTTT
CATCCTCATTGTGAGGATTA

Product: ribonuclease HIII

Products: NA

Alternate protein names: RNase HIII

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MPTPFVSQLSPSLFTTLREQLEKKGFVISIPPHTVFQGRSSTVSCTVYQSGKIVVQGKGTQEFVEFFLEPEILHSFSIQN
VQQDLRPRIGVDESGKGDFFGPLCTAGVYAPSIKSIESLYEITICDSKLISDAKIPSLARSIRSLCTCKVITLFPEKYNA
LYANFQNLNALLAWTHATIIDDLAPKPTGDVFAISDQFASSERVLLQAVRKKRADIELIQRHRAEQDVVVAAASILARDA
FLSSMQTLESQYQVRLLKGASGKVKQQAKEILRDKGQPVLEKVCKTHFKTFYEVLGSTS

Sequences:

>Translated_299_residues
MPTPFVSQLSPSLFTTLREQLEKKGFVISIPPHTVFQGRSSTVSCTVYQSGKIVVQGKGTQEFVEFFLEPEILHSFSIQN
VQQDLRPRIGVDESGKGDFFGPLCTAGVYAPSIKSIESLYEITICDSKLISDAKIPSLARSIRSLCTCKVITLFPEKYNA
LYANFQNLNALLAWTHATIIDDLAPKPTGDVFAISDQFASSERVLLQAVRKKRADIELIQRHRAEQDVVVAAASILARDA
FLSSMQTLESQYQVRLLKGASGKVKQQAKEILRDKGQPVLEKVCKTHFKTFYEVLGSTS
>Mature_298_residues
PTPFVSQLSPSLFTTLREQLEKKGFVISIPPHTVFQGRSSTVSCTVYQSGKIVVQGKGTQEFVEFFLEPEILHSFSIQNV
QQDLRPRIGVDESGKGDFFGPLCTAGVYAPSIKSIESLYEITICDSKLISDAKIPSLARSIRSLCTCKVITLFPEKYNAL
YANFQNLNALLAWTHATIIDDLAPKPTGDVFAISDQFASSERVLLQAVRKKRADIELIQRHRAEQDVVVAAASILARDAF
LSSMQTLESQYQVRLLKGASGKVKQQAKEILRDKGQPVLEKVCKTHFKTFYEVLGSTS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH3_CHLMU (Q9PL32)

Other databases:

- EMBL:   AE002160
- PIR:   D81720
- RefSeq:   NP_296655.2
- ProteinModelPortal:   Q9PL32
- SMR:   Q9PL32
- GeneID:   1246446
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0276
- TIGR:   TC_0276
- HOGENOM:   HBG549406
- OMA:   ASIIARY
- ProtClustDB:   PRK00996
- BioCyc:   CMUR243161:TC_0276-MONOMER
- BRENDA:   3.1.26.4
- GO:   GO:0005737
- HAMAP:   MF_00053
- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337
- PIRSF:   PIRSF037748
- TIGRFAMs:   TIGR00716

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 33181; Mature: 33049

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTPFVSQLSPSLFTTLREQLEKKGFVISIPPHTVFQGRSSTVSCTVYQSGKIVVQGKGT
CCCCCHHHHCHHHHHHHHHHHHHCCCEEECCCCHHCCCCCCEEEEEEEECCEEEEECCCH
QEFVEFFLEPEILHSFSIQNVQQDLRPRIGVDESGKGDFFGPLCTAGVYAPSIKSIESLY
HHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHH
EITICDSKLISDAKIPSLARSIRSLCTCKVITLFPEKYNALYANFQNLNALLAWTHATII
HHHCCCHHHHCCCCCHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
DDLAPKPTGDVFAISDQFASSERVLLQAVRKKRADIELIQRHRAEQDVVVAAASILARDA
HHCCCCCCCCEEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FLSSMQTLESQYQVRLLKGASGKVKQQAKEILRDKGQPVLEKVCKTHFKTFYEVLGSTS
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PTPFVSQLSPSLFTTLREQLEKKGFVISIPPHTVFQGRSSTVSCTVYQSGKIVVQGKGT
CCCCHHHHCHHHHHHHHHHHHHCCCEEECCCCHHCCCCCCEEEEEEEECCEEEEECCCH
QEFVEFFLEPEILHSFSIQNVQQDLRPRIGVDESGKGDFFGPLCTAGVYAPSIKSIESLY
HHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHH
EITICDSKLISDAKIPSLARSIRSLCTCKVITLFPEKYNALYANFQNLNALLAWTHATII
HHHCCCHHHHCCCCCHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
DDLAPKPTGDVFAISDQFASSERVLLQAVRKKRADIELIQRHRAEQDVVVAAASILARDA
HHCCCCCCCCEEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FLSSMQTLESQYQVRLLKGASGKVKQQAKEILRDKGQPVLEKVCKTHFKTFYEVLGSTS
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935