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The map label for this gene is era

Identifier: 13358054

GI number: 13358054

Start: 588882

End: 589796

Strand: Direct

Name: era

Synonym: UU491

Alternate gene names: 13358054

Gene position: 588882-589796 (Clockwise)

Preceding gene: 13358053

Following gene: 13358055

Centisome position: 78.34

GC content: 26.12

Gene sequence:

>915_bases
ATGGTGCTAGAAATGATTAAAAAATACGGAATCGTAGCTATTGTTGGAAAACCAAATGTTGGTAAATCAACATTAATCAA
TGCGATTATGAAAAAAAAAGTCTCAATCATTTCAAATAAGCCGCAAACAACACGCAATGCTGTTAAAGAGATTTATGAAG
ATGATGAATCAGCAATTATTTTTACTGATACGCCTGGTTTTCATGAACCATCAAATAAACTAGATTTATTTTTAAATCAT
GAAATTGAAATTTCATATAAAGAAGCAAATGTAATCTTATTCGTGACAACTATGGACAAGGAATTAGATGCCAATGATTT
TGAAATTATTAATTTAATTAAAGAAGCAAATAAAGAAAATATTATTTTAGTCATTTCAAAAGCTGAAATGGCTAAAAATC
AAGATCAAATTGATGAAAGAATCCACTTTTTAAAAAAACATATAGCATTTAAGGATGTTGTTCAAATAAGTGCTTTACAT
GTTATTAACATTGATAAATTAATTAATACAATCAAAAATTACCTTCACAAAGATGTGGTAACCGATTATTTTCGTCAAAA
AGCCGAAAAAGAAGATAAATTTGTTATTACTGAAATTATTCGTGAACAATGCTTATTAAATTTAAACCATGAAGTTCCTC
ACGGTGTTGGTGTAGAAATTGATGAAAGTAAATACAACCAAGAAGCAAATCATTGGATAATTAAAGCTTCAATAATAATT
GAAAAAAATTCTCATAAACCTATTATTATTGGCCAAAATGGTACGATGATTAAAAAAATTAGCATGGGGGCAAGAAAGCA
GTTGCATGAAATTTATGATTGTCATATTTCATTAACAATTTTTGTTAAAGTTGAAAACAATTGACGTGATAATAATAATA
TTATTAAATCATTAGGGTATAAAATTAAAAAATAA

Upstream 100 bases:

>100_bases
CATTTATTAGGTTATGATCATATAAAAATTGAAGATGAAAAAATTATGTTTGCTTTACAAGATGAAATTTTAAATGAATT
AAAAATTACAAGAAATATAA

Downstream 100 bases:

>100_bases
TGGCTGAAATAATAACTAGAGGATATTTAGTTGCGCGCCAGGATTATGATGTTTTTGATGAAATATTAACATTTATTAAT
GAATATGGTAATCGTTTTAT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MVLEMIKKYGIVAIVGKPNVGKSTLINAIMKKKVSIISNKPQTTRNAVKEIYEDDESAIIFTDTPGFHEPSNKLDLFLNH
EIEISYKEANVILFVTTMDKELDANDFEIINLIKEANKENIILVISKAEMAKNQDQIDERIHFLKKHIAFKDVVQISALH
VINIDKLINTIKNYLHKDVVTDYFRQKAEKEDKFVITEIIREQCLLNLNHEVPHGVGVEIDESKYNQEANHWIIKASIII
EKNSHKPIIIGQNGTMIKKISMGARKQLHEIYDCHISLTIFVKVENNWRDNNNIIKSLGYKIKK

Sequences:

>Translated_304_residues
MVLEMIKKYGIVAIVGKPNVGKSTLINAIMKKKVSIISNKPQTTRNAVKEIYEDDESAIIFTDTPGFHEPSNKLDLFLNH
EIEISYKEANVILFVTTMDKELDANDFEIINLIKEANKENIILVISKAEMAKNQDQIDERIHFLKKHIAFKDVVQISALH
VINIDKLINTIKNYLHKDVVTDYFRQKAEKEDKFVITEIIREQCLLNLNHEVPHGVGVEIDESKYNQEANHWIIKASIII
EKNSHKPIIIGQNGTMIKKISMGARKQLHEIYDCHISLTIFVKVENN*RDNNNIIKSLGYKIKK
>Mature_304_residues
MVLEMIKKYGIVAIVGKPNVGKSTLINAIMKKKVSIISNKPQTTRNAVKEIYEDDESAIIFTDTPGFHEPSNKLDLFLNH
EIEISYKEANVILFVTTMDKELDANDFEIINLIKEANKENIILVISKAEMAKNQDQIDERIHFLKKHIAFKDVVQISALH
VINIDKLINTIKNYLHKDVVTDYFRQKAEKEDKFVITEIIREQCLLNLNHEVPHGVGVEIDESKYNQEANHWIIKASIII
EKNSHKPIIIGQNGTMIKKISMGARKQLHEIYDCHISLTIFVKVENN*RDNNNIIKSLGYKIKK

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=294, Percent_Identity=31.2925170068027, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI87082120, Length=166, Percent_Identity=26.5060240963855, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34821; Mature: 34821

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLEMIKKYGIVAIVGKPNVGKSTLINAIMKKKVSIISNKPQTTRNAVKEIYEDDESAII
CHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEE
FTDTPGFHEPSNKLDLFLNHEIEISYKEANVILFVTTMDKELDANDFEIINLIKEANKEN
EECCCCCCCCCCCEEEEEECEEEEEEEECCEEEEEEEECCCCCCCHHHHHHHHHHCCCCC
IILVISKAEMAKNQDQIDERIHFLKKHIAFKDVVQISALHVINIDKLINTIKNYLHKDVV
EEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHH
TDYFRQKAEKEDKFVITEIIREQCLLNLNHEVPHGVGVEIDESKYNQEANHWIIKASIII
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEECHHHCCCCCCEEEEEEEEEE
EKNSHKPIIIGQNGTMIKKISMGARKQLHEIYDCHISLTIFVKVENNRDNNNIIKSLGYK
EECCCCCEEECCCCCEEEEEHHHHHHHHHHHHHEEEEEEEEEEEECCCCCHHHHHHCCCC
IKK
CCC
>Mature Secondary Structure
MVLEMIKKYGIVAIVGKPNVGKSTLINAIMKKKVSIISNKPQTTRNAVKEIYEDDESAII
CHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEE
FTDTPGFHEPSNKLDLFLNHEIEISYKEANVILFVTTMDKELDANDFEIINLIKEANKEN
EECCCCCCCCCCCEEEEEECEEEEEEEECCEEEEEEEECCCCCCCHHHHHHHHHHCCCCC
IILVISKAEMAKNQDQIDERIHFLKKHIAFKDVVQISALHVINIDKLINTIKNYLHKDVV
EEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHH
TDYFRQKAEKEDKFVITEIIREQCLLNLNHEVPHGVGVEIDESKYNQEANHWIIKASIII
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEECHHHCCCCCCEEEEEEEEEE
EKNSHKPIIIGQNGTMIKKISMGARKQLHEIYDCHISLTIFVKVENNRDNNNIIKSLGYK
EECCCCCEEECCCCCEEEEEHHHHHHHHHHHHHEEEEEEEEEEEECCCCCHHHHHHCCCC
IKK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA