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The map label for this gene is ureG

Identifier: 13357992

GI number: 13357992

Start: 491684

End: 492304

Strand: Reverse

Name: ureG

Synonym: UU429

Alternate gene names: 13357992

Gene position: 492304-491684 (Counterclockwise)

Preceding gene: 13357993

Following gene: 13357991

Centisome position: 65.49

GC content: 31.72

Gene sequence:

>621_bases
ATGAAAAGACCATTAATTATTGGTGTAGGTGGACCTGTAGGAGCAGGTAAAACAATGCTAATCGAAAGATTAACAAGATA
CCTTTCAACAAAAGGTTATAGTATGGCAGCAATTACTAATGATATTTACACTAAAGAAGATGCTAGAATTTTATTAAATA
CTTCTGTTTTACCAGCTGATCGTATTGCTGGTGTTGAAACAGGAGGATGTCCACATACAGCAATTCGTGAAGATGCTTCA
ATGAACTTTGCTGCAATTGAAGAAATGTGTGATAAACACCCTGATTTACAATTATTATTTTTAGAATCTGGTGGGGATAA
TTTATCTGCAACATTTAGTCCAGATTTAGTTGATTTTTCAATTTATATCATTGATGTTGCACAAGGAGAAAAAATTCCTC
GTAAGGGTGGTCAAGGAATGATTAAATCAGACTTATTTATTATTAATAAAGTTGATTTAGCTCCTTATGTTGGTGCTAAT
GTAGAAGTAATGAAAGCCGATACATTAAAATCACGTGGTAATAAAGATTTCTTTGTAACGAATTTAAAAACAGATGAAGG
TTTAAAATCTGTTGCTGATTGAATTGAAAAGCGTTTGCAATTAGCTTTACTAGAAGAATAA

Upstream 100 bases:

>100_bases
TCGATTATTCATGTCATAATTAAAGTTTTAGTCAACATTACATTAATCATAAAAATACCATTTAATATTTTTAAAAATTA
AAAAAGAAAGAGAATTAATT

Downstream 100 bases:

>100_bases
AGTTAACAAATGATTTTAAATAAAGAAAAAATTAAAAATTATGCTGCTTATTTATACATTAAAGTAGCATATGATCAAGC
TCATTCAAAAATGGCACATA

Product: urease complex component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKRPLIIGVGGPVGAGKTMLIERLTRYLSTKGYSMAAITNDIYTKEDARILLNTSVLPADRIAGVETGGCPHTAIREDAS
MNFAAIEEMCDKHPDLQLLFLESGGDNLSATFSPDLVDFSIYIIDVAQGEKIPRKGGQGMIKSDLFIINKVDLAPYVGAN
VEVMKADTLKSRGNKDFFVTNLKTDEGLKSVADWIEKRLQLALLEE

Sequences:

>Translated_206_residues
MKRPLIIGVGGPVGAGKTMLIERLTRYLSTKGYSMAAITNDIYTKEDARILLNTSVLPADRIAGVETGGCPHTAIREDAS
MNFAAIEEMCDKHPDLQLLFLESGGDNLSATFSPDLVDFSIYIIDVAQGEKIPRKGGQGMIKSDLFIINKVDLAPYVGAN
VEVMKADTLKSRGNKDFFVTNLKTDEGLKSVAD*IEKRLQLALLEE
>Mature_206_residues
MKRPLIIGVGGPVGAGKTMLIERLTRYLSTKGYSMAAITNDIYTKEDARILLNTSVLPADRIAGVETGGCPHTAIREDAS
MNFAAIEEMCDKHPDLQLLFLESGGDNLSATFSPDLVDFSIYIIDVAQGEKIPRKGGQGMIKSDLFIINKVDLAPYVGAN
VEVMKADTLKSRGNKDFFVTNLKTDEGLKSVAD*IEKRLQLALLEE

Specific function: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by ureG [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureG family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR012202
- InterPro:   IPR004400 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 22305; Mature: 22305

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPLIIGVGGPVGAGKTMLIERLTRYLSTKGYSMAAITNDIYTKEDARILLNTSVLPAD
CCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCCHH
RIAGVETGGCPHTAIREDASMNFAAIEEMCDKHPDLQLLFLESGGDNLSATFSPDLVDFS
HHCCCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCEEEEE
IYIIDVAQGEKIPRKGGQGMIKSDLFIINKVDLAPYVGANVEVMKADTLKSRGNKDFFVT
EEEEEECCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCCEEEEEECHHHCCCCCCEEEE
NLKTDEGLKSVADIEKRLQLALLEE
ECCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRPLIIGVGGPVGAGKTMLIERLTRYLSTKGYSMAAITNDIYTKEDARILLNTSVLPAD
CCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCCHH
RIAGVETGGCPHTAIREDASMNFAAIEEMCDKHPDLQLLFLESGGDNLSATFSPDLVDFS
HHCCCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCEEEEE
IYIIDVAQGEKIPRKGGQGMIKSDLFIINKVDLAPYVGANVEVMKADTLKSRGNKDFFVT
EEEEEECCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCCEEEEEECHHHCCCCCCEEEE
NLKTDEGLKSVADIEKRLQLALLEE
ECCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550495; 11048724 [H]