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The map label for this gene is grpE

Identifier: 13357968

GI number: 13357968

Start: 467811

End: 468467

Strand: Reverse

Name: grpE

Synonym: UU406

Alternate gene names: 13357968

Gene position: 468467-467811 (Counterclockwise)

Preceding gene: 13357969

Following gene: 13357966

Centisome position: 62.32

GC content: 24.51

Gene sequence:

>657_bases
ATGAGCAAAAATAATGAAAACATCAAACACCAAAATAATGACAAAGTTAACAACCAAGTTGATAAAAAAGAAACTAAAAA
TCATAATAAGCAAGAATTTAAATATAAAGAATTATATGAACATGAATTAAAGAAAAATAAAGAATTACAAAATATCAATA
CACTTTTAAAAGATAAAAATCAACAGTTAGAAGAGCAAATTAGTCAATTAAATCAAGATTTTATCAAACAATTAGAAACA
AAAGCAAAACAAGCACAACAAATTCTAGAACAAAAAGTTAATGAACTAGAAGCACGCCATGAAGCCAAAGTAAATGATGC
TGTCTTTAAAATTTTCAAATTTAAAATGGAACCTTTATTAGATGCAATTAATCATTTTACGAAAATTGTAAATCAAAACT
ATGATGATCCTAAAATCCAAGCTTTCATTGAGGGGTTTAAAATGTTTTCTCAAAACATGATTGATGGTTTAGATAATCTA
AAAATTACAAAAATATCTCCACAGGTTAATGATAGTTTAAATGACGAAATAATGGAAGTTTTTGAAGTTGTTGAAAACAC
AAACAAACCATCAATGCATGTAGTTGAAGTTATTAGTGATGGTTTTAAATATAATGATAAAGTTATTAAATTTGCAGTTG
TAAAAGTTGCTAAATAA

Upstream 100 bases:

>100_bases
TATCCAAAGATGAAATTGCTTATTTAAAAAATATTTCTACTCGTACAAACCAAAATGTTGAGTATTATAAAAATAAAGTA
TTAAAGGAGATTAGTAAATA

Downstream 100 bases:

>100_bases
AATAAAAAAAGTGAATAGCATTTTATAAATTGCTTTCACTTTTTTTATTTATGCTCTATAAATGCATGGTAATAAAATTG
CATTTAAAAAAATTAGCCAA

Product: heat shock protein

Products: NA

Alternate protein names: HSP-70 cofactor

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MSKNNENIKHQNNDKVNNQVDKKETKNHNKQEFKYKELYEHELKKNKELQNINTLLKDKNQQLEEQISQLNQDFIKQLET
KAKQAQQILEQKVNELEARHEAKVNDAVFKIFKFKMEPLLDAINHFTKIVNQNYDDPKIQAFIEGFKMFSQNMIDGLDNL
KITKISPQVNDSLNDEIMEVFEVVENTNKPSMHVVEVISDGFKYNDKVIKFAVVKVAK

Sequences:

>Translated_218_residues
MSKNNENIKHQNNDKVNNQVDKKETKNHNKQEFKYKELYEHELKKNKELQNINTLLKDKNQQLEEQISQLNQDFIKQLET
KAKQAQQILEQKVNELEARHEAKVNDAVFKIFKFKMEPLLDAINHFTKIVNQNYDDPKIQAFIEGFKMFSQNMIDGLDNL
KITKISPQVNDSLNDEIMEVFEVVENTNKPSMHVVEVISDGFKYNDKVIKFAVVKVAK
>Mature_217_residues
SKNNENIKHQNNDKVNNQVDKKETKNHNKQEFKYKELYEHELKKNKELQNINTLLKDKNQQLEEQISQLNQDFIKQLETK
AKQAQQILEQKVNELEARHEAKVNDAVFKIFKFKMEPLLDAINHFTKIVNQNYDDPKIQAFIEGFKMFSQNMIDGLDNLK
ITKISPQVNDSLNDEIMEVFEVVENTNKPSMHVVEVISDGFKYNDKVIKFAVVKVAK

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with dnaK and grpE. It is the nucleotide exchange factor for dnaK and may function as a thermosensor. Unfolded

COG id: COG0576

COG function: function code O; Molecular chaperone GrpE (heat shock protein)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the grpE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GRPE_UREP2 (B1AJ46)

Other databases:

- EMBL:   CP000942
- RefSeq:   YP_001752490.1
- ProteinModelPortal:   B1AJ46
- SMR:   B1AJ46
- GeneID:   6155669
- GenomeReviews:   CP000942_GR
- KEGG:   upa:UPA3_0423
- HOGENOM:   HBG734488
- OMA:   NANEYLI
- ProtClustDB:   CLSK382244
- BioCyc:   UPAR505682:UPA3_0423-MONOMER
- GO:   GO:0005739
- HAMAP:   MF_01151
- InterPro:   IPR000740
- InterPro:   IPR009012
- Gene3D:   G3DSA:2.30.22.10
- PANTHER:   PTHR21237

Pfam domain/function: PF01025 GrpE; SSF51064 GrpE_head

EC number: NA

Molecular weight: Translated: 25638; Mature: 25506

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS01071 GRPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNNENIKHQNNDKVNNQVDKKETKNHNKQEFKYKELYEHELKKNKELQNINTLLKDKN
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
QQLEEQISQLNQDFIKQLETKAKQAQQILEQKVNELEARHEAKVNDAVFKIFKFKMEPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAINHFTKIVNQNYDDPKIQAFIEGFKMFSQNMIDGLDNLKITKISPQVNDSLNDEIMEV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHH
FEVVENTNKPSMHVVEVISDGFKYNDKVIKFAVVKVAK
HHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SKNNENIKHQNNDKVNNQVDKKETKNHNKQEFKYKELYEHELKKNKELQNINTLLKDKN
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
QQLEEQISQLNQDFIKQLETKAKQAQQILEQKVNELEARHEAKVNDAVFKIFKFKMEPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAINHFTKIVNQNYDDPKIQAFIEGFKMFSQNMIDGLDNLKITKISPQVNDSLNDEIMEV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHH
FEVVENTNKPSMHVVEVISDGFKYNDKVIKFAVVKVAK
HHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA