BacMap

Definition	Ureaplasma parvum serovar 3 str. ATCC 700970, complete genome.
Accession	NC_002162
Length	751,719

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The map label for this gene is dnaJ

Identifier: 13357969

GI number: 13357969

Start: 468467

End: 469594

Strand: Reverse

Name: dnaJ

Synonym: UU407

Alternate gene names: 13357969

Gene position: 469594-468467 (Counterclockwise)

Preceding gene: 13357970

Following gene: 13357968

Centisome position: 62.47

GC content: 29.79

Gene sequence:

>1128_bases
ATGGCAAAACGTGATTATTATGAAATTTTAGGTGTTAGTAAATCAGCAACTCCTGAAGAGATTAAAGCGGCATTTCGTAA
ATTAGCAAAAGAACACCATCCTGATCGTAATAAATCTGCTGATGATACTCTTTTTAAAGAAATTAATGAAGCATATGAGG
TTTTATCTGATTCTAAAAAACGTGCACAATACGACCAATTTGGCCATGATGGTCCACAAGGTTTTAGCAGTGCTAGTGGG
TTTTCTGGGTTTAGTGGAGGATTTGGTGGTGTTGATTTTGATATTAATGACATTTTTGGCAGTTTTTTTAATAATGCTTC
TAGTTCACATAATTCATCAAACCAATATGAAACATATGATATTCACTTACGTTTACATTTAGATTTTATGGAAGCTGTTA
ATGGTATTTCTAAAAATATTAATTATGATCGTAAAATTACGTGTCATAAATGTCAAGGAACAGGTGCAAAAGATCCTAAA
GATGTCAAAATTTGCACTAAATGTCACGGTAGAGGAACTAGCATTGAAAATGTTCATTCCTTATTTGGAACAATTCAACA
AGAAGTTGAATGTCATGAGTGTGAAGGAACAGGTAAAGTTGCTAGTAGCAAATGTGAACAATGTTATGGTAAAAAAGTTA
TCAATGAACGTGTTAATTTAACTGTTGAAATCCCAGCAGGTACACGAGAAGGTGAAAAATTATTAGTAAGCAAAAAAGGT
AATATTGTCAATAATCAAGAATTTGATCTTTATTTACACATTAGTGTTAAACCATCAAAGTATTTTGCATTAGATGGTTT
AGATATTTATTCAGAAACTTACATTGATCCCATCAAAGCAATTGTTGGAGGAATAATTGAAGTAGTAACAATTAATGGTA
TTAAAACCATTGAAATTCCTTCAAATACTCCTGAAGGTAAAAAATTTAGAATTAGTGGATCAGGAATCGTTAATAAAAAA
TCAAATATTTTTGGTAAAAAGAATGGAGATTTTTATACTACAATTCGTTATGCAAAGCCAGTTGAATTATCCAAAGATGA
AATTGCTTATTTAAAAAATATTTCTACTCGTACAAACCAAAATGTTGAGTATTATAAAAATAAAGTATTAAAGGAGATTA
GTAAATAA

Upstream 100 bases:

>100_bases
TGATTATTTTTAGCAATCAGATATGATGATTGCTAATTTTTATTATTTTAGGTTATAATATATCATTGTAATTATCATAT
TTAGGGGGAATGTTTTAAGT

Downstream 100 bases:

>100_bases
TGAGCAAAAATAATGAAAACATCAAACACCAAAATAATGACAAAGTTAACAACCAAGTTGATAAAAAAGAAACTAAAAAT
CATAATAAGCAAGAATTTAA

Product: heat shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MAKRDYYEILGVSKSATPEEIKAAFRKLAKEHHPDRNKSADDTLFKEINEAYEVLSDSKKRAQYDQFGHDGPQGFSSASG
FSGFSGGFGGVDFDINDIFGSFFNNASSSHNSSNQYETYDIHLRLHLDFMEAVNGISKNINYDRKITCHKCQGTGAKDPK
DVKICTKCHGRGTSIENVHSLFGTIQQEVECHECEGTGKVASSKCEQCYGKKVINERVNLTVEIPAGTREGEKLLVSKKG
NIVNNQEFDLYLHISVKPSKYFALDGLDIYSETYIDPIKAIVGGIIEVVTINGIKTIEIPSNTPEGKKFRISGSGIVNKK
SNIFGKKNGDFYTTIRYAKPVELSKDEIAYLKNISTRTNQNVEYYKNKVLKEISK

Sequences:

>Translated_375_residues
MAKRDYYEILGVSKSATPEEIKAAFRKLAKEHHPDRNKSADDTLFKEINEAYEVLSDSKKRAQYDQFGHDGPQGFSSASG
FSGFSGGFGGVDFDINDIFGSFFNNASSSHNSSNQYETYDIHLRLHLDFMEAVNGISKNINYDRKITCHKCQGTGAKDPK
DVKICTKCHGRGTSIENVHSLFGTIQQEVECHECEGTGKVASSKCEQCYGKKVINERVNLTVEIPAGTREGEKLLVSKKG
NIVNNQEFDLYLHISVKPSKYFALDGLDIYSETYIDPIKAIVGGIIEVVTINGIKTIEIPSNTPEGKKFRISGSGIVNKK
SNIFGKKNGDFYTTIRYAKPVELSKDEIAYLKNISTRTNQNVEYYKNKVLKEISK
>Mature_374_residues
AKRDYYEILGVSKSATPEEIKAAFRKLAKEHHPDRNKSADDTLFKEINEAYEVLSDSKKRAQYDQFGHDGPQGFSSASGF
SGFSGGFGGVDFDINDIFGSFFNNASSSHNSSNQYETYDIHLRLHLDFMEAVNGISKNINYDRKITCHKCQGTGAKDPKD
VKICTKCHGRGTSIENVHSLFGTIQQEVECHECEGTGKVASSKCEQCYGKKVINERVNLTVEIPAGTREGEKLLVSKKGN
IVNNQEFDLYLHISVKPSKYFALDGLDIYSETYIDPIKAIVGGIIEVVTINGIKTIEIPSNTPEGKKFRISGSGIVNKKS
NIFGKKNGDFYTTIRYAKPVELSKDEIAYLKNISTRTNQNVEYYKNKVLKEISK

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Homo sapiens, GI205360838, Length=356, Percent_Identity=31.7415730337079, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI205360840, Length=356, Percent_Identity=31.7415730337079, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI194328758, Length=282, Percent_Identity=33.6879432624113, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI194328760, Length=282, Percent_Identity=33.6879432624113, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI4504511, Length=302, Percent_Identity=31.1258278145695, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI5031741, Length=373, Percent_Identity=28.686327077748, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI5453690, Length=364, Percent_Identity=27.1978021978022, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI7706495, Length=338, Percent_Identity=28.698224852071, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI201862518, Length=373, Percent_Identity=27.8820375335121, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI201862587, Length=373, Percent_Identity=27.8820375335121, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI56549115, Length=373, Percent_Identity=27.8820375335121, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI194328762, Length=245, Percent_Identity=30.2040816326531, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI194306642, Length=109, Percent_Identity=45.8715596330275, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI194306640, Length=109, Percent_Identity=45.8715596330275, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI6631085, Length=331, Percent_Identity=29.9093655589124, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI9558755, Length=104, Percent_Identity=46.1538461538462, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI23503241, Length=104, Percent_Identity=48.0769230769231, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI4885495, Length=66, Percent_Identity=56.0606060606061, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI47777312, Length=104, Percent_Identity=46.1538461538462, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI17388799, Length=66, Percent_Identity=56.0606060606061, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI27151736, Length=108, Percent_Identity=41.6666666666667, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI21553335, Length=73, Percent_Identity=49.3150684931507, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI88501736, Length=108, Percent_Identity=41.6666666666667, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI39204547, Length=198, Percent_Identity=29.2929292929293, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI56687498, Length=69, Percent_Identity=50.7246376811594, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI72534740, Length=120, Percent_Identity=39.1666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI22749377, Length=68, Percent_Identity=51.4705882352941, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI217035105, Length=72, Percent_Identity=45.8333333333333, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI24308127, Length=70, Percent_Identity=47.1428571428571, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI29126218, Length=67, Percent_Identity=52.2388059701493, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1786197, Length=359, Percent_Identity=33.7047353760446, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1787235, Length=295, Percent_Identity=31.1864406779661, Blast_Score=105, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17553096, Length=360, Percent_Identity=31.3888888888889, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17553098, Length=360, Percent_Identity=31.3888888888889, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17507263, Length=292, Percent_Identity=30.4794520547945, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17534355, Length=321, Percent_Identity=30.8411214953271, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI212645553, Length=72, Percent_Identity=55.5555555555556, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115532378, Length=97, Percent_Identity=45.360824742268, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115532476, Length=67, Percent_Identity=50.7462686567164, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17538236, Length=112, Percent_Identity=36.6071428571429, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554644, Length=107, Percent_Identity=41.1214953271028, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17568643, Length=68, Percent_Identity=50, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324265, Length=329, Percent_Identity=34.9544072948328, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6323870, Length=239, Percent_Identity=32.6359832635983, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321094, Length=391, Percent_Identity=30.9462915601023, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323119, Length=244, Percent_Identity=31.1475409836066, Blast_Score=105, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6324252, Length=302, Percent_Identity=26.158940397351, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320888, Length=103, Percent_Identity=44.6601941747573, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323813, Length=132, Percent_Identity=37.8787878787879, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322194, Length=105, Percent_Identity=42.8571428571429, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324321, Length=62, Percent_Identity=50, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322388, Length=113, Percent_Identity=40.7079646017699, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324828, Length=89, Percent_Identity=40.4494382022472, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI45549272, Length=374, Percent_Identity=29.144385026738, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI45552813, Length=374, Percent_Identity=29.144385026738, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI45552811, Length=374, Percent_Identity=29.144385026738, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646562, Length=283, Percent_Identity=31.095406360424, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24646560, Length=283, Percent_Identity=31.095406360424, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24646558, Length=283, Percent_Identity=31.095406360424, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24646556, Length=283, Percent_Identity=31.095406360424, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI21357547, Length=283, Percent_Identity=31.095406360424, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI28574949, Length=349, Percent_Identity=26.0744985673352, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20129487, Length=275, Percent_Identity=31.6363636363636, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24584014, Length=275, Percent_Identity=31.6363636363636, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI85726398, Length=387, Percent_Identity=28.6821705426357, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24658562, Length=304, Percent_Identity=27.6315789473684, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24658555, Length=304, Percent_Identity=27.6315789473684, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19920464, Length=378, Percent_Identity=25.6613756613757, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24654066, Length=103, Percent_Identity=48.5436893203884, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654070, Length=103, Percent_Identity=48.5436893203884, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654068, Length=103, Percent_Identity=48.5436893203884, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654072, Length=103, Percent_Identity=48.5436893203884, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI18858081, Length=322, Percent_Identity=26.0869565217391, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24584630, Length=123, Percent_Identity=39.0243902439024, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17648033, Length=123, Percent_Identity=39.0243902439024, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI161077138, Length=64, Percent_Identity=56.25, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21358273, Length=121, Percent_Identity=37.1900826446281, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641698, Length=62, Percent_Identity=51.6129032258064, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641696, Length=62, Percent_Identity=51.6129032258064, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17737735, Length=67, Percent_Identity=49.2537313432836, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574723, Length=67, Percent_Identity=49.2537313432836, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24668523, Length=67, Percent_Identity=49.2537313432836, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAJ_UREPA (Q9PQ82)

Other databases:

- EMBL:   AF222894
- RefSeq:   NP_078243.1
- ProteinModelPortal:   Q9PQ82
- GeneID:   876239
- GenomeReviews:   AF222894_GR
- KEGG:   uur:UU407
- HOGENOM:   HBG635315
- OMA:   KERCTAC
- ProtClustDB:   CLSK2298921
- BioCyc:   UURE95667:UU407-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01152
- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:2.10.230.10
- PANTHER:   PTHR11821
- PRINTS:   PR00625
- SMART:   SM00271
- TIGRFAMs:   TIGR02349

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG; SSF46565 DnaJ_N; SSF49493 HSP40_DnaJ_pep; SSF57938 HSP_DnaJ_cys-rich

EC number: NA

Molecular weight: Translated: 41841; Mature: 41710

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2; PS51188 ZF_CR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRDYYEILGVSKSATPEEIKAAFRKLAKEHHPDRNKSADDTLFKEINEAYEVLSDSKK
CCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHH
RAQYDQFGHDGPQGFSSASGFSGFSGGFGGVDFDINDIFGSFFNNASSSHNSSNQYETYD
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEE
IHLRLHLDFMEAVNGISKNINYDRKITCHKCQGTGAKDPKDVKICTKCHGRGTSIENVHS
EEEEEEEEHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCEEECCCCCCCHHHHHH
LFGTIQQEVECHECEGTGKVASSKCEQCYGKKVINERVNLTVEIPAGTREGEKLLVSKKG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCC
NIVNNQEFDLYLHISVKPSKYFALDGLDIYSETYIDPIKAIVGGIIEVVTINGIKTIEIP
CCCCCCCEEEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHEEEEEECCEEEEECC
SNTPEGKKFRISGSGIVNKKSNIFGKKNGDFYTTIRYAKPVELSKDEIAYLKNISTRTNQ
CCCCCCCEEEEECCCEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCC
NVEYYKNKVLKEISK
CHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKRDYYEILGVSKSATPEEIKAAFRKLAKEHHPDRNKSADDTLFKEINEAYEVLSDSKK
CCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHH
RAQYDQFGHDGPQGFSSASGFSGFSGGFGGVDFDINDIFGSFFNNASSSHNSSNQYETYD
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEE
IHLRLHLDFMEAVNGISKNINYDRKITCHKCQGTGAKDPKDVKICTKCHGRGTSIENVHS
EEEEEEEEHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCEEECCCCCCCHHHHHH
LFGTIQQEVECHECEGTGKVASSKCEQCYGKKVINERVNLTVEIPAGTREGEKLLVSKKG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCC
NIVNNQEFDLYLHISVKPSKYFALDGLDIYSETYIDPIKAIVGGIIEVVTINGIKTIEIP
CCCCCCCEEEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHEEEEEECCEEEEECC
SNTPEGKKFRISGSGIVNKKSNIFGKKNGDFYTTIRYAKPVELSKDEIAYLKNISTRTNQ
CCCCCCCEEEEECCCEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCC
NVEYYKNKVLKEISK
CHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11048724