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The map label for this gene is ppa

Identifier: 13357875

GI number: 13357875

Start: 358615

End: 359160

Strand: Reverse

Name: ppa

Synonym: UU315

Alternate gene names: 13357875

Gene position: 359160-358615 (Counterclockwise)

Preceding gene: 13357883

Following gene: 13357874

Centisome position: 47.78

GC content: 29.3

Gene sequence:

>546_bases
ATGAAATTAAATGTAACTATTGAAATTCCAAAGAACTCAAATATTAAATATGAATATGATCGTGCAACTAAAGAAATCAT
GGTTGATCGTATCTTACACGGTTCAATGGTTTATCCTCATAATTATGGTTTTTTAAAAGAAGCATTAGATTATGATGGTG
ACGAATTGGATGTTTTGGTTTTTGCTGATCAAGCATTCCAACCAGGAATTAAAGTACCTGCACGTGTTTTGGGCGCCATG
AAAATGATTGATGGAGGAGAAACAGATACTAAATTATTGGCAGTTATTGATGTTGATCCTCGTTATAAACACATTAATAA
TTTCAAAGATATTCCATTACATTGATTAGCAGAAGTGCAAGATTTCTTTGAAAATTACAAAAACTTACAAAATAAAAAAG
TTAAAATCTTGGGGTTTGAAGATGAAATATGAGCTCAAAAAGAATATGAAGAATGTGTTCTTTTAATGAAAGAATATGGC
CATCTTAAAAAAGATGAATTTGTAACTAAAATGATGAAAGAACGTCCAGAAAAGTACATTAAATAA

Upstream 100 bases:

>100_bases
TGGTAATCAATTATTTTTATCAAATATAAAATAAGACAAACATAATATAATTATAAAATATTAGTTAAGGATATTTAGAT
TAATAAAAAGGAGAGGTAGT

Downstream 100 bases:

>100_bases
TGCTTCAAAAAATCAAAAATTCAAATTTTTATATAATAATTAAAAAATTTAATCAATCACTTAGAAAAATAAATTTTTTT
GAGAAAATTATTTTAAAAAT

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MKLNVTIEIPKNSNIKYEYDRATKEIMVDRILHGSMVYPHNYGFLKEALDYDGDELDVLVFADQAFQPGIKVPARVLGAM
KMIDGGETDTKLLAVIDVDPRYKHINNFKDIPLHWLAEVQDFFENYKNLQNKKVKILGFEDEIWAQKEYEECVLLMKEYG
HLKKDEFVTKMMKERPEKYIK

Sequences:

>Translated_181_residues
MKLNVTIEIPKNSNIKYEYDRATKEIMVDRILHGSMVYPHNYGFLKEALDYDGDELDVLVFADQAFQPGIKVPARVLGAM
KMIDGGETDTKLLAVIDVDPRYKHINNFKDIPLH*LAEVQDFFENYKNLQNKKVKILGFEDEI*AQKEYEECVLLMKEYG
HLKKDEFVTKMMKERPEKYIK
>Mature_181_residues
MKLNVTIEIPKNSNIKYEYDRATKEIMVDRILHGSMVYPHNYGFLKEALDYDGDELDVLVFADQAFQPGIKVPARVLGAM
KMIDGGETDTKLLAVIDVDPRYKHINNFKDIPLH*LAEVQDFFENYKNLQNKKVKILGFEDEI*AQKEYEECVLLMKEYG
HLKKDEFVTKMMKERPEKYIK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=146, Percent_Identity=41.7808219178082, Blast_Score=104, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71984883, Length=180, Percent_Identity=30, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71984889, Length=180, Percent_Identity=30, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71984880, Length=180, Percent_Identity=30, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71984895, Length=180, Percent_Identity=30, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 20902; Mature: 20902

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNVTIEIPKNSNIKYEYDRATKEIMVDRILHGSMVYPHNYGFLKEALDYDGDELDVLV
CEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHCCCCCCEEEEE
FADQAFQPGIKVPARVLGAMKMIDGGETDTKLLAVIDVDPRYKHINNFKDIPLHLAEVQD
EECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHCCCCCCCHHHHHHHH
FFENYKNLQNKKVKILGFEDEIAQKEYEECVLLMKEYGHLKKDEFVTKMMKERPEKYIK
HHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLNVTIEIPKNSNIKYEYDRATKEIMVDRILHGSMVYPHNYGFLKEALDYDGDELDVLV
CEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHCCCCCCEEEEE
FADQAFQPGIKVPARVLGAMKMIDGGETDTKLLAVIDVDPRYKHINNFKDIPLHLAEVQD
EECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHCCCCCCCHHHHHHHH
FFENYKNLQNKKVKILGFEDEIAQKEYEECVLLMKEYGHLKKDEFVTKMMKERPEKYIK
HHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11048724 [H]