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The map label for this gene is arsb

Identifier: 15004807

GI number: 15004807

Start: 110272

End: 111321

Strand: Direct

Name: arsb

Synonym: CA_P0104

Alternate gene names: 15004807

Gene position: 110272-111321 (Clockwise)

Preceding gene: 15004806

Following gene: 15004808

Centisome position: 57.43

GC content: 32.67

Gene sequence:

>1050_bases
TTGAATAAAACATCAAAATTATTTTGGCTTGATCGTTATTTAACTATATGGATTTTCACTGCAATGGCAATCGGTATACT
TTTAGGATGGACTTTTCCAGGGCTTTCTACTACATTGTCAAGTTTATCAGTAGGAACCACCTCTATTCCCATGGCTATTG
GACTTATAGTTATGCTTTATCCACCACTTGCAAAAGTTAACTATAAAGAGCTCTATAAAGTTTTTAAAAATCCCAAAGTT
TTAGGTTTATCACTTTTACAAAATTGGATTGTGGGACCAATTTTAATGTTTATAATAGCAATCATATTTTTAAAATCATA
TCCAGCATTTATGACTGGGCTTATATTAATTGGTCTTGCAAGGTGCATTGCCATGGTTATTGTATGGAATGGTTTGGCCG
ATGGAGATACAGAGTATGCAGCAGCTCTTGTGGCCTTCAACTCAATTTTTCAGGTTATTTTTTATTCAGTATACTGCTAT
ATATTTATAACAGTTTTACCAACAGTATTTGGGTTGAATGGTTATAAAGTTGATATTTCAATGGTAAAAGTAGCTGGTTC
TGTAGCCATTTATCTTGGTATACCATTTGCAGCTGGACTTCTTACAAGGCTAATATTAGAACCTAAAATGGGAACTGAAT
GGTATACAAAAAAGTTTGTACCTAAGGTGAGTCCGCTAGCATTAATTGCTCTACTTTTTACTATAGTAATCATGTTTACT
TATAAGGGAAAATATATAGTTGAACTTCCGATGGATGTTATAAGAATTGCAGTTCCTCTTTTAGTATATTTTATAATAAT
GTTTTCGGTATCATTTTTTATAAGTTATAAATCAGGAATAGATTATAAAAAAACAACAACTCTATCATTTACAGCCGCAA
GCAATAACTTTGAACTTGCCATAGCCGTTGCAGTTGCAGTTTTCGGAATACAGTCAAAAGAAGCCTTTACGGCAGTTATA
GGTCCTCTAGTAGAAGTACCTGTTATGATAGCACTCGTAAATGTAGCTCTATACTGGAGAAAAAAATATTTTAGTAACGG
AGGAAAATAA

Upstream 100 bases:

>100_bases
CTAGAACAATGTAAAAAAGATTTACGACAATTAAAAAAATATAAAGAAAGTGGCCTTAACTGCGATGAGTTAAAGGAAAC
TAAATTAGGGGGAAAATAAA

Downstream 100 bases:

>100_bases
CTATGAAACCAAAAGTAGCATTTATATGCGTACACAATTCCTGTAGATCTCAAATGGCTGAAGCTCTTGGAAAGCTATTT
GCAGCTGACACCTTTGAAGC

Product: heavy metal resistance membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MNKTSKLFWLDRYLTIWIFTAMAIGILLGWTFPGLSTTLSSLSVGTTSIPMAIGLIVMLYPPLAKVNYKELYKVFKNPKV
LGLSLLQNWIVGPILMFIIAIIFLKSYPAFMTGLILIGLARCIAMVIVWNGLADGDTEYAAALVAFNSIFQVIFYSVYCY
IFITVLPTVFGLNGYKVDISMVKVAGSVAIYLGIPFAAGLLTRLILEPKMGTEWYTKKFVPKVSPLALIALLFTIVIMFT
YKGKYIVELPMDVIRIAVPLLVYFIIMFSVSFFISYKSGIDYKKTTTLSFTAASNNFELAIAVAVAVFGIQSKEAFTAVI
GPLVEVPVMIALVNVALYWRKKYFSNGGK

Sequences:

>Translated_349_residues
MNKTSKLFWLDRYLTIWIFTAMAIGILLGWTFPGLSTTLSSLSVGTTSIPMAIGLIVMLYPPLAKVNYKELYKVFKNPKV
LGLSLLQNWIVGPILMFIIAIIFLKSYPAFMTGLILIGLARCIAMVIVWNGLADGDTEYAAALVAFNSIFQVIFYSVYCY
IFITVLPTVFGLNGYKVDISMVKVAGSVAIYLGIPFAAGLLTRLILEPKMGTEWYTKKFVPKVSPLALIALLFTIVIMFT
YKGKYIVELPMDVIRIAVPLLVYFIIMFSVSFFISYKSGIDYKKTTTLSFTAASNNFELAIAVAVAVFGIQSKEAFTAVI
GPLVEVPVMIALVNVALYWRKKYFSNGGK
>Mature_349_residues
MNKTSKLFWLDRYLTIWIFTAMAIGILLGWTFPGLSTTLSSLSVGTTSIPMAIGLIVMLYPPLAKVNYKELYKVFKNPKV
LGLSLLQNWIVGPILMFIIAIIFLKSYPAFMTGLILIGLARCIAMVIVWNGLADGDTEYAAALVAFNSIFQVIFYSVYCY
IFITVLPTVFGLNGYKVDISMVKVAGSVAIYLGIPFAAGLLTRLILEPKMGTEWYTKKFVPKVSPLALIALLFTIVIMFT
YKGKYIVELPMDVIRIAVPLLVYFIIMFSVSFFISYKSGIDYKKTTTLSFTAASNNFELAIAVAVAVFGIQSKEAFTAVI
GPLVEVPVMIALVNVALYWRKKYFSNGGK

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=335, Percent_Identity=33.7313432835821, Blast_Score=164, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 38693; Mature: 38693

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTSKLFWLDRYLTIWIFTAMAIGILLGWTFPGLSTTLSSLSVGTTSIPMAIGLIVMLY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHC
PPLAKVNYKELYKVFKNPKVLGLSLLQNWIVGPILMFIIAIIFLKSYPAFMTGLILIGLA
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RCIAMVIVWNGLADGDTEYAAALVAFNSIFQVIFYSVYCYIFITVLPTVFGLNGYKVDIS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHH
MVKVAGSVAIYLGIPFAAGLLTRLILEPKMGTEWYTKKFVPKVSPLALIALLFTIVIMFT
HEEHHCCEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
YKGKYIVELPMDVIRIAVPLLVYFIIMFSVSFFISYKSGIDYKKTTTLSFTAASNNFELA
CCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHH
IAVAVAVFGIQSKEAFTAVIGPLVEVPVMIALVNVALYWRKKYFSNGGK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNKTSKLFWLDRYLTIWIFTAMAIGILLGWTFPGLSTTLSSLSVGTTSIPMAIGLIVMLY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHC
PPLAKVNYKELYKVFKNPKVLGLSLLQNWIVGPILMFIIAIIFLKSYPAFMTGLILIGLA
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RCIAMVIVWNGLADGDTEYAAALVAFNSIFQVIFYSVYCYIFITVLPTVFGLNGYKVDIS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHH
MVKVAGSVAIYLGIPFAAGLLTRLILEPKMGTEWYTKKFVPKVSPLALIALLFTIVIMFT
HEEHHCCEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
YKGKYIVELPMDVIRIAVPLLVYFIIMFSVSFFISYKSGIDYKKTTTLSFTAASNNFELA
CCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHH
IAVAVAVFGIQSKEAFTAVIGPLVEVPVMIALVNVALYWRKKYFSNGGK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]