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The map label for this gene is arsc

Identifier: 15004808

GI number: 15004808

Start: 111324

End: 111734

Strand: Direct

Name: arsc

Synonym: CA_P0105

Alternate gene names: 15004808

Gene position: 111324-111734 (Clockwise)

Preceding gene: 15004807

Following gene: 15004810

Centisome position: 57.98

GC content: 33.58

Gene sequence:

>411_bases
ATGAAACCAAAAGTAGCATTTATATGCGTACACAATTCCTGTAGATCTCAAATGGCTGAAGCTCTTGGAAAGCTATTTGC
AGCTGACACCTTTGAAGCGTACTCCGCCGGCACAGAATTAAAAGATAACATAAATCAAGATGCAGTAAGAATTATAAGGG
ATTTATACGACATTGATATGAATGAAAAACATAAATCAAAGCTTTTAAAAGATCTTCCAAAGGTCGACATAGTGATAAAA
ATGGGCTGCAATGTAGTATGTCCTTTTGTGCTCTCAAAACACACAGAAGATTGGGGCTTAGACGATCCTTCAGGAAAAAG
TGATGAAGAATTTATAAGAACGGCAAAAACCATTGAAGAAAAAGTTAAGGATTTAGCTAAAAGAATTATAAATAAAGAAA
TTGAATTATAA

Upstream 100 bases:

>100_bases
CAGTTATAGGTCCTCTAGTAGAAGTACCTGTTATGATAGCACTCGTAAATGTAGCTCTATACTGGAGAAAAAAATATTTT
AGTAACGGAGGAAAATAACT

Downstream 100 bases:

>100_bases
ATAAAAAGTACAATAGGGTACACATGAAGAAATGTGTACCCTATTGTACTTATTTTATAATATTCATAATATCTTCTACT
ATCTGAACATCTGTAAGTCT

Product: arsenate reductase C

Products: NA

Alternate protein names: Arsenate reductase 1; Arsenical pump modifier 1; Low molecular weight protein-tyrosine-phosphatase 1 [H]

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MKPKVAFICVHNSCRSQMAEALGKLFAADTFEAYSAGTELKDNINQDAVRIIRDLYDIDMNEKHKSKLLKDLPKVDIVIK
MGCNVVCPFVLSKHTEDWGLDDPSGKSDEEFIRTAKTIEEKVKDLAKRIINKEIEL

Sequences:

>Translated_136_residues
MKPKVAFICVHNSCRSQMAEALGKLFAADTFEAYSAGTELKDNINQDAVRIIRDLYDIDMNEKHKSKLLKDLPKVDIVIK
MGCNVVCPFVLSKHTEDWGLDDPSGKSDEEFIRTAKTIEEKVKDLAKRIINKEIEL
>Mature_136_residues
MKPKVAFICVHNSCRSQMAEALGKLFAADTFEAYSAGTELKDNINQDAVRIIRDLYDIDMNEKHKSKLLKDLPKVDIVIK
MGCNVVCPFVLSKHTEDWGLDDPSGKSDEEFIRTAKTIEEKVKDLAKRIINKEIEL

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15427; Mature: 15427

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKVAFICVHNSCRSQMAEALGKLFAADTFEAYSAGTELKDNINQDAVRIIRDLYDIDM
CCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCC
NEKHKSKLLKDLPKVDIVIKMGCNVVCPFVLSKHTEDWGLDDPSGKSDEEFIRTAKTIEE
CHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KVKDLAKRIINKEIEL
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPKVAFICVHNSCRSQMAEALGKLFAADTFEAYSAGTELKDNINQDAVRIIRDLYDIDM
CCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCC
NEKHKSKLLKDLPKVDIVIKMGCNVVCPFVLSKHTEDWGLDDPSGKSDEEFIRTAKTIEE
CHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KVKDLAKRIINKEIEL
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA