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The map label for this gene is gpmA [H]

Identifier: 15595003

GI number: 15595003

Start: 697571

End: 698332

Strand: Direct

Name: gpmA [H]

Synonym: BB0658

Alternate gene names: 15595003

Gene position: 697571-698332 (Clockwise)

Preceding gene: 15595001

Following gene: 15595006

Centisome position: 76.6

GC content: 34.38

Gene sequence:

>762_bases
ATGCTAGGAGATTTTATGTATAAATTAGTTTTAGTAAGACACGGAGAGAGTGAGTGGAATAAAGAAAATCTTTTTACTGG
TTGGACAGATGTTAAACTTTCTGACAAGGGTATCGATGAGGCTGTTGAGGCGGGTTTGCTTCTCAAACAAGAAGGCTATT
CTTTTGATATTGCTTTTAGTTCTTTGTTGTCAAGAGCTAATGACACTTTAAATATTATTTTGCGAGAATTAGGGCAATCT
TATATTAGTGTAAAAAAAACCTGGAGATTAAATGAAAGGCACTATGGAGCTTTGCAAGGTTTAAATAAGTCAGAAACAGC
TGCAAAATATGGGGAAGATAAGGTTTTAATTTGGAGACGTAGTTATGATGTGCCCCCAATGTCTTTGGATGAGTCTGATG
ATCGTCATCCCATAAAAGATCCAAGATATAAACATATCCCCAAAAGGGAACTTCCTTCAACAGAGTGCCTTAAAGATACT
GTTGCAAGAGTTATTCCTTATTGGACTGATGAGATTGCAAAAGAAGTTCTTGAAGGTAAAAAAGTTATTGTTGCTGCTCA
CGGTAATTCTTTAAGAGCGCTTGTTAAATATTTTGACAATTTAAGTGAAGAAGATGTTTTAAAGCTTAACATTCCCACAG
GCATTCCTTTAGTTTACGAATTAGATAAAGATTTAAATCCCATTAAACATTACTATCTAGGTGATGAGAGCAAAATTAAA
AAGGCAATGGAATCTGTTGCTAGTCAAGGAAAGTTAAAGTAA

Upstream 100 bases:

>100_bases
TAATGTATTTTAAAGTATATCATTATTTAATTACTAAGGTTTAAATCTTGACTAGATTTTATGCTAATTTATAATTATTA
GTATTGGTAAATAAAATAAT

Downstream 100 bases:

>100_bases
CGATTTATTTGTATTAAAGTGTAAATAAGTCATATAATTATGACTTATTTTTTATTAATTTTAAGGCTTAAACGTATTTG
CTTGTAATCTTTTCAAAGCG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MLGDFMYKLVLVRHGESEWNKENLFTGWTDVKLSDKGIDEAVEAGLLLKQEGYSFDIAFSSLLSRANDTLNIILRELGQS
YISVKKTWRLNERHYGALQGLNKSETAAKYGEDKVLIWRRSYDVPPMSLDESDDRHPIKDPRYKHIPKRELPSTECLKDT
VARVIPYWTDEIAKEVLEGKKVIVAAHGNSLRALVKYFDNLSEEDVLKLNIPTGIPLVYELDKDLNPIKHYYLGDESKIK
KAMESVASQGKLK

Sequences:

>Translated_253_residues
MLGDFMYKLVLVRHGESEWNKENLFTGWTDVKLSDKGIDEAVEAGLLLKQEGYSFDIAFSSLLSRANDTLNIILRELGQS
YISVKKTWRLNERHYGALQGLNKSETAAKYGEDKVLIWRRSYDVPPMSLDESDDRHPIKDPRYKHIPKRELPSTECLKDT
VARVIPYWTDEIAKEVLEGKKVIVAAHGNSLRALVKYFDNLSEEDVLKLNIPTGIPLVYELDKDLNPIKHYYLGDESKIK
KAMESVASQGKLK
>Mature_253_residues
MLGDFMYKLVLVRHGESEWNKENLFTGWTDVKLSDKGIDEAVEAGLLLKQEGYSFDIAFSSLLSRANDTLNIILRELGQS
YISVKKTWRLNERHYGALQGLNKSETAAKYGEDKVLIWRRSYDVPPMSLDESDDRHPIKDPRYKHIPKRELPSTECLKDT
VARVIPYWTDEIAKEVLEGKKVIVAAHGNSLRALVKYFDNLSEEDVLKLNIPTGIPLVYELDKDLNPIKHYYLGDESKIK
KAMESVASQGKLK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI4505753, Length=250, Percent_Identity=55.6, Blast_Score=278, Evalue=3e-75,
Organism=Homo sapiens, GI50593010, Length=253, Percent_Identity=51.7786561264822, Blast_Score=276, Evalue=1e-74,
Organism=Homo sapiens, GI71274132, Length=250, Percent_Identity=52.8, Blast_Score=260, Evalue=1e-69,
Organism=Homo sapiens, GI4502445, Length=255, Percent_Identity=46.6666666666667, Blast_Score=250, Evalue=8e-67,
Organism=Homo sapiens, GI40353764, Length=255, Percent_Identity=46.6666666666667, Blast_Score=250, Evalue=8e-67,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=53.7037037037037, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI9966849, Length=255, Percent_Identity=27.4509803921569, Blast_Score=71, Evalue=7e-13,
Organism=Escherichia coli, GI1786970, Length=246, Percent_Identity=59.7560975609756, Blast_Score=305, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=53.2520325203252, Blast_Score=253, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6324516, Length=282, Percent_Identity=32.6241134751773, Blast_Score=146, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6320183, Length=299, Percent_Identity=32.4414715719064, Blast_Score=138, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6324857, Length=213, Percent_Identity=23.0046948356808, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI85725270, Length=251, Percent_Identity=54.5816733067729, Blast_Score=278, Evalue=2e-75,
Organism=Drosophila melanogaster, GI85725272, Length=251, Percent_Identity=54.5816733067729, Blast_Score=278, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24650981, Length=251, Percent_Identity=54.5816733067729, Blast_Score=278, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24646216, Length=251, Percent_Identity=51.792828685259, Blast_Score=273, Evalue=6e-74,
Organism=Drosophila melanogaster, GI28571815, Length=257, Percent_Identity=39.6887159533074, Blast_Score=191, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24648979, Length=248, Percent_Identity=39.5161290322581, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI28571817, Length=248, Percent_Identity=39.5161290322581, Blast_Score=189, Evalue=1e-48,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 28943; Mature: 28943

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGDFMYKLVLVRHGESEWNKENLFTGWTDVKLSDKGIDEAVEAGLLLKQEGYSFDIAFS
CCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCEEEECCCCEEHHHHH
SLLSRANDTLNIILRELGQSYISVKKTWRLNERHYGALQGLNKSETAAKYGEDKVLIWRR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHCCCCEEEEEEE
SYDVPPMSLDESDDRHPIKDPRYKHIPKRELPSTECLKDTVARVIPYWTDEIAKEVLEGK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCC
KVIVAAHGNSLRALVKYFDNLSEEDVLKLNIPTGIPLVYELDKDLNPIKHYYLGDESKIK
EEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHHCCCHHHHH
KAMESVASQGKLK
HHHHHHHHCCCCC
>Mature Secondary Structure
MLGDFMYKLVLVRHGESEWNKENLFTGWTDVKLSDKGIDEAVEAGLLLKQEGYSFDIAFS
CCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCEEEECCCCEEHHHHH
SLLSRANDTLNIILRELGQSYISVKKTWRLNERHYGALQGLNKSETAAKYGEDKVLIWRR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHCCCCEEEEEEE
SYDVPPMSLDESDDRHPIKDPRYKHIPKRELPSTECLKDTVARVIPYWTDEIAKEVLEGK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCC
KVIVAAHGNSLRALVKYFDNLSEEDVLKLNIPTGIPLVYELDKDLNPIKHYYLGDESKIK
EEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHHCCCHHHHH
KAMESVASQGKLK
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA