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The map label for this gene is ptsG [H]

Identifier: 15594990

GI number: 15594990

Start: 683423

End: 684967

Strand: Direct

Name: ptsG [H]

Synonym: BB0645

Alternate gene names: 15594990

Gene position: 683423-684967 (Clockwise)

Preceding gene: 15594989

Following gene: 15594994

Centisome position: 75.04

GC content: 35.28

Gene sequence:

>1545_bases
ATGTTAAAGGGTTTTGAACAAGCTCAGAAATTTGGACGTTCTTTTATGCTTCCAATTGCTATTTTGCCAGCAGCGGGGCT
GCTTTTAGGAATTGGAGGCTCTCTTTCTAATCCAGAAACCGTTAGGACGTATTCTTTTTTGAATATATTCTTCTTACAAT
CAGTTTTCAAAATAATGAGTGCGTCGGGTTCTATTATTTTTTCAAATTTAGCGCCAATATTTTCTATTGGAATTGCTGTT
GGACTTGCAAAATCAGATAAAGGCACATCTGGAATCGCAGCATTTATTGGCTACCTTGTAATGAATGCTACTATTGGAGT
TTTAATTGATGTGTCAGGCAGAGCGGAGTCTTTCTCTAGTGGTGCTGTGGGTTTTGTTCTTGGAATTAAGACTTTAGAAA
CGGGGGTTTTTGGCGGGGTTGTAGTTGGTATTTTGACTTATTATCTTCATTCTAGATTTAACAAAGTAGATTTACCTAAG
GTTCTTGGATTTTTTTCTGGATCTAGATTTGTTCCGATCATTGTTTCTTTTTCTAGTATTTTTCTTGCTGTTATTATGTT
TCTTGTTTGGCCATTTGTACAAAGTGGAATTAATAAAGTAGGGGGCTTAGTAGATTCAACCGGTTATATTGGAACACTTA
TTTATGGGATTTTTTTAAGGATGCTTGGACCTTTTGGTCTTCATCATATATTTTATTTGCCATTTTGGACAACAGGCCTT
GGGGGATCTGTTATTATTGATGGAAAGTTAATTGAAGGAACTCAGAATATTTTCTTTGCAGAACTTGCTGCCCAAGGTAC
AGATAGATTTTTTATCGGAACTAGCCGTTTTATGAGTGGACGATTTATTACCATGATGTTTGGTTTGCCCGGAGCTGCAC
TTGCTCTATATTACACTGCAAAGCGCGAGGAGAGAACAAAAGTTTTTGGTCTTTTGATGTCTTCAGCGCTAACGTCATTT
TTAACAGGTATAACAGAACCTCTTGAATTTTCTTTTCTTTTTGTAGCCCCTATTCTTTATGTTGTTCATGCTACATTTGA
TGGATTTGCTTTCATGCTAGCGCATATTTTGCAAATTACAATAGGTCAAACGTTTTCTGGAGGGTTTGTCGATTTTATTC
TTTTTGGCATTTTGCAGGGAAATTCAAGAACTAATTGGCTTTTGGTGCCAGTTATAGGCATTGTTTGGTTTTTTCTTTAC
TACTTTACTTTTATATTTTTAATAAATAAGTTTGATTTTAAAACTCCGGGTAGAACGCAAGATTTAAATTCTGAAGATTC
TCCAAGTTCTAAGAGTAGTGAATTTGAAGAAAATTATGCCACTAAGGTTATTATTGGGCTTGGTGGTGCTTCAAATATTG
TTGAGCTTGATTGTTGTGCAACTAGGCTTAGAATTACAGTAAGGGATGTTCTTAAAGTTTCTGAAAAAATTTTAAAAAAA
ACTGGTTCTAAAGGAGTAATTATTAAAGGCAATGGGGTTCAGGTAGTTTACGGACCAGGTGTTAGTGTTCTTAAGAATGA
AATAGAAGAATTGCTAGAGGCTTGA

Upstream 100 bases:

>100_bases
GCCCGCTGAGATTACTAAAAAATTTGTAGAAAAAATAAATCAGATTAAAAAATAATTTTAAACTTAAGGGTTAATTTATT
TTTTATTTTAGGAGGGTTTT

Downstream 100 bases:

>100_bases
TTTTTTTAATAAGTAATAGCTTAAGGCTATTACTTATTAATCTTGTTTATGAAATCAAATACATACTTTGTGAAGTATGA
TGTGTTTTGGGCGCTTTTGT

Product: PTS system, glucose-specific IIBC component (ptsG)

Products: NA

Alternate protein names: EIICBA-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MLKGFEQAQKFGRSFMLPIAILPAAGLLLGIGGSLSNPETVRTYSFLNIFFLQSVFKIMSASGSIIFSNLAPIFSIGIAV
GLAKSDKGTSGIAAFIGYLVMNATIGVLIDVSGRAESFSSGAVGFVLGIKTLETGVFGGVVVGILTYYLHSRFNKVDLPK
VLGFFSGSRFVPIIVSFSSIFLAVIMFLVWPFVQSGINKVGGLVDSTGYIGTLIYGIFLRMLGPFGLHHIFYLPFWTTGL
GGSVIIDGKLIEGTQNIFFAELAAQGTDRFFIGTSRFMSGRFITMMFGLPGAALALYYTAKREERTKVFGLLMSSALTSF
LTGITEPLEFSFLFVAPILYVVHATFDGFAFMLAHILQITIGQTFSGGFVDFILFGILQGNSRTNWLLVPVIGIVWFFLY
YFTFIFLINKFDFKTPGRTQDLNSEDSPSSKSSEFEENYATKVIIGLGGASNIVELDCCATRLRITVRDVLKVSEKILKK
TGSKGVIIKGNGVQVVYGPGVSVLKNEIEELLEA

Sequences:

>Translated_514_residues
MLKGFEQAQKFGRSFMLPIAILPAAGLLLGIGGSLSNPETVRTYSFLNIFFLQSVFKIMSASGSIIFSNLAPIFSIGIAV
GLAKSDKGTSGIAAFIGYLVMNATIGVLIDVSGRAESFSSGAVGFVLGIKTLETGVFGGVVVGILTYYLHSRFNKVDLPK
VLGFFSGSRFVPIIVSFSSIFLAVIMFLVWPFVQSGINKVGGLVDSTGYIGTLIYGIFLRMLGPFGLHHIFYLPFWTTGL
GGSVIIDGKLIEGTQNIFFAELAAQGTDRFFIGTSRFMSGRFITMMFGLPGAALALYYTAKREERTKVFGLLMSSALTSF
LTGITEPLEFSFLFVAPILYVVHATFDGFAFMLAHILQITIGQTFSGGFVDFILFGILQGNSRTNWLLVPVIGIVWFFLY
YFTFIFLINKFDFKTPGRTQDLNSEDSPSSKSSEFEENYATKVIIGLGGASNIVELDCCATRLRITVRDVLKVSEKILKK
TGSKGVIIKGNGVQVVYGPGVSVLKNEIEELLEA
>Mature_514_residues
MLKGFEQAQKFGRSFMLPIAILPAAGLLLGIGGSLSNPETVRTYSFLNIFFLQSVFKIMSASGSIIFSNLAPIFSIGIAV
GLAKSDKGTSGIAAFIGYLVMNATIGVLIDVSGRAESFSSGAVGFVLGIKTLETGVFGGVVVGILTYYLHSRFNKVDLPK
VLGFFSGSRFVPIIVSFSSIFLAVIMFLVWPFVQSGINKVGGLVDSTGYIGTLIYGIFLRMLGPFGLHHIFYLPFWTTGL
GGSVIIDGKLIEGTQNIFFAELAAQGTDRFFIGTSRFMSGRFITMMFGLPGAALALYYTAKREERTKVFGLLMSSALTSF
LTGITEPLEFSFLFVAPILYVVHATFDGFAFMLAHILQITIGQTFSGGFVDFILFGILQGNSRTNWLLVPVIGIVWFFLY
YFTFIFLINKFDFKTPGRTQDLNSEDSPSSKSSEFEENYATKVIIGLGGASNIVELDCCATRLRITVRDVLKVSEKILKK
TGSKGVIIKGNGVQVVYGPGVSVLKNEIEELLEA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=513, Percent_Identity=40.5458089668616, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1787343, Length=517, Percent_Identity=38.4912959381045, Blast_Score=336, Evalue=2e-93,
Organism=Escherichia coli, GI1786894, Length=508, Percent_Identity=35.8267716535433, Blast_Score=257, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 55843; Mature: 55843

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKGFEQAQKFGRSFMLPIAILPAAGLLLGIGGSLSNPETVRTYSFLNIFFLQSVFKIMS
CCCCHHHHHHHCCHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
ASGSIIFSNLAPIFSIGIAVGLAKSDKGTSGIAAFIGYLVMNATIGVLIDVSGRAESFSS
CCCCEEEHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
GAVGFVLGIKTLETGVFGGVVVGILTYYLHSRFNKVDLPKVLGFFSGSRFVPIIVSFSSI
CCEEHHEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHH
FLAVIMFLVWPFVQSGINKVGGLVDSTGYIGTLIYGIFLRMLGPFGLHHIFYLPFWTTGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHEEEHHHHCCC
GGSVIIDGKLIEGTQNIFFAELAAQGTDRFFIGTSRFMSGRFITMMFGLPGAALALYYTA
CCCEEECCEEECCCHHHHHHHHHHCCCCEEEEEHHHHHCCCEEEEEECCCHHHHHHHHHH
KREERTKVFGLLMSSALTSFLTGITEPLEFSFLFVAPILYVVHATFDGFAFMLAHILQIT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGQTFSGGFVDFILFGILQGNSRTNWLLVPVIGIVWFFLYYFTFIFLINKFDFKTPGRTQ
HCCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DLNSEDSPSSKSSEFEENYATKVIIGLGGASNIVELDCCATRLRITVRDVLKVSEKILKK
CCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
TGSKGVIIKGNGVQVVYGPGVSVLKNEIEELLEA
CCCCCEEEECCCEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKGFEQAQKFGRSFMLPIAILPAAGLLLGIGGSLSNPETVRTYSFLNIFFLQSVFKIMS
CCCCHHHHHHHCCHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
ASGSIIFSNLAPIFSIGIAVGLAKSDKGTSGIAAFIGYLVMNATIGVLIDVSGRAESFSS
CCCCEEEHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
GAVGFVLGIKTLETGVFGGVVVGILTYYLHSRFNKVDLPKVLGFFSGSRFVPIIVSFSSI
CCEEHHEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHH
FLAVIMFLVWPFVQSGINKVGGLVDSTGYIGTLIYGIFLRMLGPFGLHHIFYLPFWTTGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHEEEHHHHCCC
GGSVIIDGKLIEGTQNIFFAELAAQGTDRFFIGTSRFMSGRFITMMFGLPGAALALYYTA
CCCEEECCEEECCCHHHHHHHHHHCCCCEEEEEHHHHHCCCEEEEEECCCHHHHHHHHHH
KREERTKVFGLLMSSALTSFLTGITEPLEFSFLFVAPILYVVHATFDGFAFMLAHILQIT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGQTFSGGFVDFILFGILQGNSRTNWLLVPVIGIVWFFLYYFTFIFLINKFDFKTPGRTQ
HCCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DLNSEDSPSSKSSEFEENYATKVIIGLGGASNIVELDCCATRLRITVRDVLKVSEKILKK
CCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
TGSKGVIIKGNGVQVVYGPGVSVLKNEIEELLEA
CCCCCEEEECCCEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA