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The map label for this gene is mcpB [H]

Identifier: 15594942

GI number: 15594942

Start: 618828

End: 621035

Strand: Direct

Name: mcpB [H]

Synonym: BB0597

Alternate gene names: 15594942

Gene position: 618828-621035 (Clockwise)

Preceding gene: 15594938

Following gene: 15594944

Centisome position: 67.95

GC content: 26.36

Gene sequence:

>2208_bases
ATGACAGATGAGAATTTAATTGATGTTAATCTGAAAAATACTAAACGATTTCTTTATCTAGTTTTATTTGGATTCCTTTT
TTTAAATTTTTTATTCATAGGCTATGCTTATATGAATCATAAAAATGAATATTTGGATCGCTTTAAATTTGATTCTAAGT
TGTTTTTAAACAGTGTGTCTGCTGTTATTAAAGCCAAATATTCGGAATCCTCTAGGTTTCTTGAGGAGCTTATAAGAGAT
AGCTATAGGTTTGGGATATTGGTGAATTCTTCAAAAAGCTTTCTTTTGTCTTCAAGTTTAAAATTAGGTGATAGTTTGGA
TGAAAATAGTGATTTGTTTTTAAGGTCAAGGGAATTTAACTCTATAGATAAAATTTTTAAAACTATTCCTTTAGCAGAAG
ATTCACTTGAAGGTATATTTTATATTCCTATAGGGAAAAATGTTTTAATATCAAATTCAAATTTTTCATCTTTAGGCTTA
AAAGATGTTAGATTGGATCCAATTTATTCTGTTCCTGTAGAAAAAAATTCTAAGTATTATTCAAGATATATGCAAATAGA
TGGGAAAATTTATTCTATAATAAGTTTTCCAGTTAGAGATTCTGTTTCAACATTGGGTGTGATAGGGATTTTAATATGCT
TTGATGAGTCGTTAGATATTATTGAAAATCAGTTGTATTCTTCTCTTAAATTTGGTAGTAAAAATTATAATTTTTTTATG
CTTGACAGAAATTACATGCCCATTTTTTCAAACCTTAATAATCTTCAGGCCAAATCTTTTTCTACAGCTTATAGTGAGAA
TTTTTTGAGTAAAGTTATAGCTTATGCTAAAAAAGATTCTTCTAGCTCTCAGTACACTTTTAATTATGAAAGAGATTTTT
ATTCTTTAAACTTTGTAAAAACCGATGATTTTTTGACTCAGGGGCTTATTTTAAATGTCAATTCCATTCCTATTATGTTT
AAATCAAATTGGGTTATATTTGTTGCATTTTTATTATTGTCTTTTGCAATTATTTTTTATTTATGCAATACTTTTGTTTT
TTCATTAATTAATGATTTTAACAGAATTGTTGACTATCAAAAATCAAAAAGCGATCCTTTTAGTCTTGAATCTCCCTTAG
AGGTTAAGTATTCTTCATCTATTATTTCTTATATTAGTTCAAAGCTAGATAATCTGTCTTCTAAGAGTAATGAATCTTTT
GAGAAGATAAAATTTTATTCTGAAGATTTGAATGAATATTTGGAACAAATAGAAACTGCTATATCAAATACTGAGAGTAT
AGATTCTAGCATTTTAGTTTACGAACAACTAAGAGATACTTTTTCTAGATTTGAAAAATCAATTGTTGATATTTTAAAAG
GCTTTGAATCTATTGCTGATCCGATTAATGATCACAATAAATATATATCAGAAATCTCTTCAAATTTTGAAGAGAGTGTT
AGTTTTTTCTATAGTATAGATAAAAATTTAGAAATTTTTAATAAGGTTGCTACTATAAATTCTACTGATATTGAAAATAT
TAAAAGTAAGGTTTTTGATTTAAATATTGTTTTTGAAAATGTGAATAAAAATTTTGCAGATCTTTTGTCTCAAACAAATA
GTTTGCAAAGTGTAAATAAACTTTTAGTTTCAATTTCAGCTCAGACCAATATGCTTGCTATGAATGCAGCAATTGAAGCA
GCAAAAGCAGGTGATGCAGGTAAAAGTTTTGCAGTTGTTGCTGAGGAGATTAGAAAGCTTGCTATTAATTCTGGAAAATA
TTCTAAAACCATTAAAGATGAACTTAAAACGGTCGACAGCATTATTGCAGTAATTAATTCAGAGATTGATACAATTTATA
AAAATTTCATAGACATTCAAGATAATGTGGACAACAATTTTTCAAGACACGAGAAAGTAGATCTTACTCTTGCTAAGCAT
TTTAAAGAAATTGGCGAGTTTAAAGAAAGGTATTTGTCTCACGATACTAAGATCAGAGATGCTAAGAATATGTATAAAGA
AATATTTAATAATCATTATTTTATTAGTGGCAAGTTTAACAACTTTAGTCAAGATTTAAAAGAGTTTAAAGTTTCTAAGA
TGAATTTAGATGCGGTAAGTTCTCTTCAAGAATATTCATCTTTAGTAAAGTCTTCTAAGGATAAGATATTAAAGACAAAG
GAATTGATTCAAAAGATTAATGATGAGATTAAAGATATTCTTTTTTAG

Upstream 100 bases:

>100_bases
TTGCCAATTGTTATTAGTAATTATTTATATATGATTTATGAAGGTGAAAGTTTTGTTTTAAGATTTTAATCATACTAATA
TTTATGTTTGGAGAGCTTTT

Downstream 100 bases:

>100_bases
TTTTTTTGATTATTTGAATCCTATGTAAAGAACTTCTTCTTCTAGTAAAAGTCCAGTTTTCAAGTAGACCTCAGCTTTTA
CTTTTTCAATTAAGCTTTTT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 735; Mature: 734

Protein sequence:

>735_residues
MTDENLIDVNLKNTKRFLYLVLFGFLFLNFLFIGYAYMNHKNEYLDRFKFDSKLFLNSVSAVIKAKYSESSRFLEELIRD
SYRFGILVNSSKSFLLSSSLKLGDSLDENSDLFLRSREFNSIDKIFKTIPLAEDSLEGIFYIPIGKNVLISNSNFSSLGL
KDVRLDPIYSVPVEKNSKYYSRYMQIDGKIYSIISFPVRDSVSTLGVIGILICFDESLDIIENQLYSSLKFGSKNYNFFM
LDRNYMPIFSNLNNLQAKSFSTAYSENFLSKVIAYAKKDSSSSQYTFNYERDFYSLNFVKTDDFLTQGLILNVNSIPIMF
KSNWVIFVAFLLLSFAIIFYLCNTFVFSLINDFNRIVDYQKSKSDPFSLESPLEVKYSSSIISYISSKLDNLSSKSNESF
EKIKFYSEDLNEYLEQIETAISNTESIDSSILVYEQLRDTFSRFEKSIVDILKGFESIADPINDHNKYISEISSNFEESV
SFFYSIDKNLEIFNKVATINSTDIENIKSKVFDLNIVFENVNKNFADLLSQTNSLQSVNKLLVSISAQTNMLAMNAAIEA
AKAGDAGKSFAVVAEEIRKLAINSGKYSKTIKDELKTVDSIIAVINSEIDTIYKNFIDIQDNVDNNFSRHEKVDLTLAKH
FKEIGEFKERYLSHDTKIRDAKNMYKEIFNNHYFISGKFNNFSQDLKEFKVSKMNLDAVSSLQEYSSLVKSSKDKILKTK
ELIQKINDEIKDILF

Sequences:

>Translated_735_residues
MTDENLIDVNLKNTKRFLYLVLFGFLFLNFLFIGYAYMNHKNEYLDRFKFDSKLFLNSVSAVIKAKYSESSRFLEELIRD
SYRFGILVNSSKSFLLSSSLKLGDSLDENSDLFLRSREFNSIDKIFKTIPLAEDSLEGIFYIPIGKNVLISNSNFSSLGL
KDVRLDPIYSVPVEKNSKYYSRYMQIDGKIYSIISFPVRDSVSTLGVIGILICFDESLDIIENQLYSSLKFGSKNYNFFM
LDRNYMPIFSNLNNLQAKSFSTAYSENFLSKVIAYAKKDSSSSQYTFNYERDFYSLNFVKTDDFLTQGLILNVNSIPIMF
KSNWVIFVAFLLLSFAIIFYLCNTFVFSLINDFNRIVDYQKSKSDPFSLESPLEVKYSSSIISYISSKLDNLSSKSNESF
EKIKFYSEDLNEYLEQIETAISNTESIDSSILVYEQLRDTFSRFEKSIVDILKGFESIADPINDHNKYISEISSNFEESV
SFFYSIDKNLEIFNKVATINSTDIENIKSKVFDLNIVFENVNKNFADLLSQTNSLQSVNKLLVSISAQTNMLAMNAAIEA
AKAGDAGKSFAVVAEEIRKLAINSGKYSKTIKDELKTVDSIIAVINSEIDTIYKNFIDIQDNVDNNFSRHEKVDLTLAKH
FKEIGEFKERYLSHDTKIRDAKNMYKEIFNNHYFISGKFNNFSQDLKEFKVSKMNLDAVSSLQEYSSLVKSSKDKILKTK
ELIQKINDEIKDILF
>Mature_734_residues
TDENLIDVNLKNTKRFLYLVLFGFLFLNFLFIGYAYMNHKNEYLDRFKFDSKLFLNSVSAVIKAKYSESSRFLEELIRDS
YRFGILVNSSKSFLLSSSLKLGDSLDENSDLFLRSREFNSIDKIFKTIPLAEDSLEGIFYIPIGKNVLISNSNFSSLGLK
DVRLDPIYSVPVEKNSKYYSRYMQIDGKIYSIISFPVRDSVSTLGVIGILICFDESLDIIENQLYSSLKFGSKNYNFFML
DRNYMPIFSNLNNLQAKSFSTAYSENFLSKVIAYAKKDSSSSQYTFNYERDFYSLNFVKTDDFLTQGLILNVNSIPIMFK
SNWVIFVAFLLLSFAIIFYLCNTFVFSLINDFNRIVDYQKSKSDPFSLESPLEVKYSSSIISYISSKLDNLSSKSNESFE
KIKFYSEDLNEYLEQIETAISNTESIDSSILVYEQLRDTFSRFEKSIVDILKGFESIADPINDHNKYISEISSNFEESVS
FFYSIDKNLEIFNKVATINSTDIENIKSKVFDLNIVFENVNKNFADLLSQTNSLQSVNKLLVSISAQTNMLAMNAAIEAA
KAGDAGKSFAVVAEEIRKLAINSGKYSKTIKDELKTVDSIIAVINSEIDTIYKNFIDIQDNVDNNFSRHEKVDLTLAKHF
KEIGEFKERYLSHDTKIRDAKNMYKEIFNNHYFISGKFNNFSQDLKEFKVSKMNLDAVSSLQEYSSLVKSSKDKILKTKE
LIQKINDEIKDILF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=310, Percent_Identity=21.6129032258065, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI2367378, Length=304, Percent_Identity=23.3552631578947, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788195, Length=209, Percent_Identity=26.7942583732057, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787690, Length=184, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 84571; Mature: 84440

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDENLIDVNLKNTKRFLYLVLFGFLFLNFLFIGYAYMNHKNEYLDRFKFDSKLFLNSVS
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHH
AVIKAKYSESSRFLEELIRDSYRFGILVNSSKSFLLSSSLKLGDSLDENSDLFLRSREFN
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHCCCCCCCCCCCCCCEEEECCCCH
SIDKIFKTIPLAEDSLEGIFYIPIGKNVLISNSNFSSLGLKDVRLDPIYSVPVEKNSKYY
HHHHHHHHCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCEECCCEEECCCCCCCHHH
SRYMQIDGKIYSIISFPVRDSVSTLGVIGILICFDESLDIIENQLYSSLKFGSKNYNFFM
HHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEE
LDRNYMPIFSNLNNLQAKSFSTAYSENFLSKVIAYAKKDSSSSQYTFNYERDFYSLNFVK
EECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEEE
TDDFLTQGLILNVNSIPIMFKSNWVIFVAFLLLSFAIIFYLCNTFVFSLINDFNRIVDYQ
CCHHHHCCEEEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSKSDPFSLESPLEVKYSSSIISYISSKLDNLSSKSNESFEKIKFYSEDLNEYLEQIETA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ISNTESIDSSILVYEQLRDTFSRFEKSIVDILKGFESIADPINDHNKYISEISSNFEESV
HCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
SFFYSIDKNLEIFNKVATINSTDIENIKSKVFDLNIVFENVNKNFADLLSQTNSLQSVNK
HHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHH
LLVSISAQTNMLAMNAAIEAAKAGDAGKSFAVVAEEIRKLAINSGKYSKTIKDELKTVDS
HHHHHCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
IIAVINSEIDTIYKNFIDIQDNVDNNFSRHEKVDLTLAKHFKEIGEFKERYLSHDTKIRD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AKNMYKEIFNNHYFISGKFNNFSQDLKEFKVSKMNLDAVSSLQEYSSLVKSSKDKILKTK
HHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELIQKINDEIKDILF
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDENLIDVNLKNTKRFLYLVLFGFLFLNFLFIGYAYMNHKNEYLDRFKFDSKLFLNSVS
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHH
AVIKAKYSESSRFLEELIRDSYRFGILVNSSKSFLLSSSLKLGDSLDENSDLFLRSREFN
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHCCCCCCCCCCCCCCEEEECCCCH
SIDKIFKTIPLAEDSLEGIFYIPIGKNVLISNSNFSSLGLKDVRLDPIYSVPVEKNSKYY
HHHHHHHHCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCEECCCEEECCCCCCCHHH
SRYMQIDGKIYSIISFPVRDSVSTLGVIGILICFDESLDIIENQLYSSLKFGSKNYNFFM
HHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEE
LDRNYMPIFSNLNNLQAKSFSTAYSENFLSKVIAYAKKDSSSSQYTFNYERDFYSLNFVK
EECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEEE
TDDFLTQGLILNVNSIPIMFKSNWVIFVAFLLLSFAIIFYLCNTFVFSLINDFNRIVDYQ
CCHHHHCCEEEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSKSDPFSLESPLEVKYSSSIISYISSKLDNLSSKSNESFEKIKFYSEDLNEYLEQIETA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ISNTESIDSSILVYEQLRDTFSRFEKSIVDILKGFESIADPINDHNKYISEISSNFEESV
HCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
SFFYSIDKNLEIFNKVATINSTDIENIKSKVFDLNIVFENVNKNFADLLSQTNSLQSVNK
HHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHH
LLVSISAQTNMLAMNAAIEAAKAGDAGKSFAVVAEEIRKLAINSGKYSKTIKDELKTVDS
HHHHHCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
IIAVINSEIDTIYKNFIDIQDNVDNNFSRHEKVDLTLAKHFKEIGEFKERYLSHDTKIRD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AKNMYKEIFNNHYFISGKFNNFSQDLKEFKVSKMNLDAVSSLQEYSSLVKSSKDKILKTK
HHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELIQKINDEIKDILF
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]