Click here to switch to the map view.

The map label for this gene is cysS [H]

Identifier: 15594944

GI number: 15594944

Start: 622005

End: 623447

Strand: Direct

Name: cysS [H]

Synonym: BB0599

Alternate gene names: 15594944

Gene position: 622005-623447 (Clockwise)

Preceding gene: 15594942

Following gene: 15594945

Centisome position: 68.3

GC content: 29.52

Gene sequence:

>1443_bases
ATGATTTTAAAGTTATATAATACTAGAACAAAGGATTTTTCAGAATTAACAAATTTTGAAAATGTTAAAGTGTATGCTTG
CGGGCCTACTGTTTATAATTATGCTCACATCGGGAATTTTAGAACTTATATTTTTGGAGATTTGTTAATTAAAACTTTAA
GGTTTTTGGGGTATAAAGTTAATTATGCGATGAATATTACAGATATTGGACATTTAACAGGTGATCTTGATGATGGAGAA
GATAAGGTTGCTAAGACCGCAAGAGAGAAGGGCCTTACAGTTTATGAGATTAGTGAATTTTTCACAGAGGCTTTTTTTAA
CGATTGTAGAAAATTAAACATTGTATATCCCGACAAAGTTCTTGTTGCAAGTAAACATATTCCCATAATGATAGAGGTTG
TTAAAATTCTTGAAGAAAAAAAAATTACTTATTTTTCTAATGGTAATGTGTATTTTGATACTTCTTGTTTTAAAAGCTAT
GGTGAGATGGCCGGCATTGATCTTATTGATAAAGATATGACTTTACCCAGAGTTGATGTTGATAAATTTAAAAGGAATAA
AACCGATTTTGTTTTGTGGTTTACTAATTCTAAGTTTAAAGATCAGGAGATGAAATGGGATTCTCCTTGGGGATTTGGTT
ATCCAAGTTGGCATTTGGAGTGCGCTGCGATGAATTTGGAGTATTTCAAAGATGCTCTTGATATTCATTTGGGAGGAGTT
GATCATATTGGAGTTCACCACATAAATGAAATAGCAATAGCAGAGTGTTTTTTGAATAAAAAATGGTGTGATGTCTTTGT
TCATGGAGAATTTTTGATTATGGATTATAATAAGATGTCAAAGTCACGTGGAAATTTTATTACAGTTAAAGATTTAGAAG
ATCAAAATTTTTCCCCTCTTGATTTTAGATATTTATGTTTGACATCGCACTACAGGAACCAATTAAAATTTTCATTAGAT
AATCTTCAAGCAAGCAAGATTGCTAGAGAAAATTTGATAAACAAGCTAAGTTATTTTTATGAATCTTTAGATCCAGTTGA
TTTAAATACACTTAATAAGGATTTAAAAAATTTTGGTTTTAGTGTAGAAAAAGAATATTATGACTCTTTTGTAGAAAAAA
TTTCTTTTGATTTAAATGTTGCTCAAGGATTGGCTTTGCTTTGGGAGATAATTAAATCTGACAATCTAAGCTTTGTTTCA
AAGCTTAGATTAGCTTTTATTTTTGATGAGATTATGTCACTTAATCTGAGAGAAGAAATTTTAAAAAATTTACAAAACCA
TGACGTAGTTATTGATGAGAATATGAAAGCTTTGATTGAAGAGAGAAGAATAGCTAAATGTGAAAAAAATTTTAAGCGTG
CTGATGAAATCAGAGATTTTTTTGCCAAAAAAGGTTTTGTTTTGGTTGATACTAAGGAAGGAACTAAGGTTAAAAGAGGC
TAA

Upstream 100 bases:

>100_bases
GAGGCTTAATATTGATTTTTTTAAGAAAATTATTTAGGCTTTTAGGCATACGTACTTAATAATAAATTAGATTTTTTATT
TTTTCAATTTTGAGAAATGT

Downstream 100 bases:

>100_bases
CATTTGGCTATTTTTTTAAAAAACAAATATTTTTATTTAAGCCTGATTTTTATTATTTTTTTATTTTTATTTGTTTTTTC
TGGATTTTTATTTTATTCAA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MILKLYNTRTKDFSELTNFENVKVYACGPTVYNYAHIGNFRTYIFGDLLIKTLRFLGYKVNYAMNITDIGHLTGDLDDGE
DKVAKTAREKGLTVYEISEFFTEAFFNDCRKLNIVYPDKVLVASKHIPIMIEVVKILEEKKITYFSNGNVYFDTSCFKSY
GEMAGIDLIDKDMTLPRVDVDKFKRNKTDFVLWFTNSKFKDQEMKWDSPWGFGYPSWHLECAAMNLEYFKDALDIHLGGV
DHIGVHHINEIAIAECFLNKKWCDVFVHGEFLIMDYNKMSKSRGNFITVKDLEDQNFSPLDFRYLCLTSHYRNQLKFSLD
NLQASKIARENLINKLSYFYESLDPVDLNTLNKDLKNFGFSVEKEYYDSFVEKISFDLNVAQGLALLWEIIKSDNLSFVS
KLRLAFIFDEIMSLNLREEILKNLQNHDVVIDENMKALIEERRIAKCEKNFKRADEIRDFFAKKGFVLVDTKEGTKVKRG

Sequences:

>Translated_480_residues
MILKLYNTRTKDFSELTNFENVKVYACGPTVYNYAHIGNFRTYIFGDLLIKTLRFLGYKVNYAMNITDIGHLTGDLDDGE
DKVAKTAREKGLTVYEISEFFTEAFFNDCRKLNIVYPDKVLVASKHIPIMIEVVKILEEKKITYFSNGNVYFDTSCFKSY
GEMAGIDLIDKDMTLPRVDVDKFKRNKTDFVLWFTNSKFKDQEMKWDSPWGFGYPSWHLECAAMNLEYFKDALDIHLGGV
DHIGVHHINEIAIAECFLNKKWCDVFVHGEFLIMDYNKMSKSRGNFITVKDLEDQNFSPLDFRYLCLTSHYRNQLKFSLD
NLQASKIARENLINKLSYFYESLDPVDLNTLNKDLKNFGFSVEKEYYDSFVEKISFDLNVAQGLALLWEIIKSDNLSFVS
KLRLAFIFDEIMSLNLREEILKNLQNHDVVIDENMKALIEERRIAKCEKNFKRADEIRDFFAKKGFVLVDTKEGTKVKRG
>Mature_480_residues
MILKLYNTRTKDFSELTNFENVKVYACGPTVYNYAHIGNFRTYIFGDLLIKTLRFLGYKVNYAMNITDIGHLTGDLDDGE
DKVAKTAREKGLTVYEISEFFTEAFFNDCRKLNIVYPDKVLVASKHIPIMIEVVKILEEKKITYFSNGNVYFDTSCFKSY
GEMAGIDLIDKDMTLPRVDVDKFKRNKTDFVLWFTNSKFKDQEMKWDSPWGFGYPSWHLECAAMNLEYFKDALDIHLGGV
DHIGVHHINEIAIAECFLNKKWCDVFVHGEFLIMDYNKMSKSRGNFITVKDLEDQNFSPLDFRYLCLTSHYRNQLKFSLD
NLQASKIARENLINKLSYFYESLDPVDLNTLNKDLKNFGFSVEKEYYDSFVEKISFDLNVAQGLALLWEIIKSDNLSFVS
KLRLAFIFDEIMSLNLREEILKNLQNHDVVIDENMKALIEERRIAKCEKNFKRADEIRDFFAKKGFVLVDTKEGTKVKRG

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=324, Percent_Identity=34.5679012345679, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI62240992, Length=244, Percent_Identity=32.7868852459016, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI10835051, Length=244, Percent_Identity=32.7868852459016, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI21269877, Length=244, Percent_Identity=32.7868852459016, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI303304987, Length=244, Percent_Identity=32.7868852459016, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1786737, Length=491, Percent_Identity=32.9938900203666, Blast_Score=231, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17509797, Length=251, Percent_Identity=31.8725099601594, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17509795, Length=251, Percent_Identity=31.8725099601594, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324082, Length=347, Percent_Identity=29.1066282420749, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI19922218, Length=510, Percent_Identity=30.1960784313725, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI19922364, Length=243, Percent_Identity=30.4526748971193, Blast_Score=132, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 56023; Mature: 56023

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKLYNTRTKDFSELTNFENVKVYACGPTVYNYAHIGNFRTYIFGDLLIKTLRFLGYKV
CEEEEECCCCCCHHHHCCCCCEEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHCEEE
NYAMNITDIGHLTGDLDDGEDKVAKTAREKGLTVYEISEFFTEAFFNDCRKLNIVYPDKV
EEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHEEEEECCCEE
LVASKHIPIMIEVVKILEEKKITYFSNGNVYFDTSCFKSYGEMAGIDLIDKDMTLPRVDV
EEECCCCCHHHHHHHHHHHCCEEEEECCCEEEECHHHHHHHHHCCCEEECCCCCCCCCCH
DKFKRNKTDFVLWFTNSKFKDQEMKWDSPWGFGYPSWHLECAAMNLEYFKDALDIHLGGV
HHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHEEECCC
DHIGVHHINEIAIAECFLNKKWCDVFVHGEFLIMDYNKMSKSRGNFITVKDLEDQNFSPL
CCCCHHHHHHHHHHHHHCCCCEEEEEEECEEEEEECHHHCCCCCCEEEEEECCCCCCCCC
DFRYLCLTSHYRNQLKFSLDNLQASKIARENLINKLSYFYESLDPVDLNTLNKDLKNFGF
CEEEEEEEHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
SVEKEYYDSFVEKISFDLNVAQGLALLWEIIKSDNLSFVSKLRLAFIFDEIMSLNLREEI
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHH
LKNLQNHDVVIDENMKALIEERRIAKCEKNFKRADEIRDFFAKKGFVLVDTKEGTKVKRG
HHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MILKLYNTRTKDFSELTNFENVKVYACGPTVYNYAHIGNFRTYIFGDLLIKTLRFLGYKV
CEEEEECCCCCCHHHHCCCCCEEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHCEEE
NYAMNITDIGHLTGDLDDGEDKVAKTAREKGLTVYEISEFFTEAFFNDCRKLNIVYPDKV
EEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHEEEEECCCEE
LVASKHIPIMIEVVKILEEKKITYFSNGNVYFDTSCFKSYGEMAGIDLIDKDMTLPRVDV
EEECCCCCHHHHHHHHHHHCCEEEEECCCEEEECHHHHHHHHHCCCEEECCCCCCCCCCH
DKFKRNKTDFVLWFTNSKFKDQEMKWDSPWGFGYPSWHLECAAMNLEYFKDALDIHLGGV
HHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHEEECCC
DHIGVHHINEIAIAECFLNKKWCDVFVHGEFLIMDYNKMSKSRGNFITVKDLEDQNFSPL
CCCCHHHHHHHHHHHHHCCCCEEEEEEECEEEEEECHHHCCCCCCEEEEEECCCCCCCCC
DFRYLCLTSHYRNQLKFSLDNLQASKIARENLINKLSYFYESLDPVDLNTLNKDLKNFGF
CEEEEEEEHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
SVEKEYYDSFVEKISFDLNVAQGLALLWEIIKSDNLSFVSKLRLAFIFDEIMSLNLREEI
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHH
LKNLQNHDVVIDENMKALIEERRIAKCEKNFKRADEIRDFFAKKGFVLVDTKEGTKVKRG
HHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA