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The map label for this gene is cssR

Identifier: 16080354

GI number: 16080354

Start: 3385724

End: 3386401

Strand: Direct

Name: cssR

Synonym: BSU33010

Alternate gene names: 16080354

Gene position: 3385724-3386401 (Clockwise)

Preceding gene: 16080351

Following gene: 255767751

Centisome position: 80.31

GC content: 45.72

Gene sequence:

>678_bases
TTGTCATACACCATTTATCTAGTTGAAGATGAGGATAACCTGAATGAACTGCTGACGAAGTATTTAGAGAATGAGGGCTG
GAACATTACATCTTTTACGAAAGGTGAAGACGCCAGAAAGAAAATGACACCGTCTCCCCACCTATGGATTCTCGATATCA
TGCTGCCGGATACCGACGGCTATACATTAATAAAAGAAATCAAGGCGAAAGATCCTGACGTGCCGGTCATTTTTATTTCC
GCCCGAGATGCGGATATTGACAGAGTGCTTGGCTTAGAGCTTGGCAGCAATGACTACATTTCAAAGCCGTTTTTGCCGCG
GGAGCTGATTATCCGTGTGCAAAAGCTGCTGCAGCTCGTATATAAGGAAGCTCCTCCTGTCCAAAAAAATGAAATTGCCG
TCTCCTCGTATCGGGTCGCTGAAGACGCCCGCGAGGTCTATGACGAAAACGGGAATATCATCAATTTGACGTCAAAGGAA
TTTGATCTGCTGCTATTATTTATCCATCATAAAGGGCATCCATACTCTCGTGAGGATATCCTCCTAAAAGTGTGGGGACA
TGACTACTTCGGAACAGACCGGGTCGTTGATGATCTCGTCCGGAGACTGCGCAGAAAGATGCCTGAATTGAAGGTGGAGA
CGATTTACGGTTTCGGCTACAGGATGATGTCATCATGA

Upstream 100 bases:

>100_bases
ACATTGTGGGATAAAAATGAAAAGAATATGTGAAATTATGAAAATTGCCTGCCGTATGTTAAAACTAGTTTATAATGACG
TTGAAAGGATGTGAAGAGCC

Downstream 100 bases:

>100_bases
AAAACAAGCCGCTCGCGTTTCAGATATGGGTTGTCATATCCGGCATCCTGTTAGCGATATCGATTTTACTGCTTGTGTTA
TTTTCAAACACGCTGCGAGA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MSYTIYLVEDEDNLNELLTKYLENEGWNITSFTKGEDARKKMTPSPHLWILDIMLPDTDGYTLIKEIKAKDPDVPVIFIS
ARDADIDRVLGLELGSNDYISKPFLPRELIIRVQKLLQLVYKEAPPVQKNEIAVSSYRVAEDAREVYDENGNIINLTSKE
FDLLLLFIHHKGHPYSREDILLKVWGHDYFGTDRVVDDLVRRLRRKMPELKVETIYGFGYRMMSS

Sequences:

>Translated_225_residues
MSYTIYLVEDEDNLNELLTKYLENEGWNITSFTKGEDARKKMTPSPHLWILDIMLPDTDGYTLIKEIKAKDPDVPVIFIS
ARDADIDRVLGLELGSNDYISKPFLPRELIIRVQKLLQLVYKEAPPVQKNEIAVSSYRVAEDAREVYDENGNIINLTSKE
FDLLLLFIHHKGHPYSREDILLKVWGHDYFGTDRVVDDLVRRLRRKMPELKVETIYGFGYRMMSS
>Mature_224_residues
SYTIYLVEDEDNLNELLTKYLENEGWNITSFTKGEDARKKMTPSPHLWILDIMLPDTDGYTLIKEIKAKDPDVPVIFISA
RDADIDRVLGLELGSNDYISKPFLPRELIIRVQKLLQLVYKEAPPVQKNEIAVSSYRVAEDAREVYDENGNIINLTSKEF
DLLLLFIHHKGHPYSREDILLKVWGHDYFGTDRVVDDLVRRLRRKMPELKVETIYGFGYRMMSS

Specific function: Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=32.8947368421053, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=36.1607142857143, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=35.2173913043478, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=33.6206896551724, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=33.7777777777778, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=35.2173913043478, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=34.375, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=32.7586206896552, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=33.7777777777778, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=30.5936073059361, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=28.8288288288288, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=28.448275862069, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=27.1493212669683, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=28.4444444444444, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790299, Length=130, Percent_Identity=29.2307692307692, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=31.8965517241379, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CSSR_BACSU (O32192)

Other databases:

- EMBL:   Z93941
- EMBL:   AJ223978
- EMBL:   AL009126
- PIR:   C70045
- RefSeq:   NP_391181.1
- ProteinModelPortal:   O32192
- SMR:   O32192
- EnsemblBacteria:   EBBACT00000001336
- GeneID:   938594
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU33010
- NMPDR:   fig|224308.1.peg.3307
- GenoList:   BSU33010
- GeneTree:   EBGT00070000031925
- HOGENOM:   HBG753323
- OMA:   FMSARNE
- ProtClustDB:   CLSK887853
- BioCyc:   BSUB:BSU33010-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00448
- SMART:   SM00862

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C; SSF46894 Bipartite_resp_reg_C-effector; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 26212; Mature: 26081

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYTIYLVEDEDNLNELLTKYLENEGWNITSFTKGEDARKKMTPSPHLWILDIMLPDTDG
CCEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCCCEEEEEEEECCCCC
YTLIKEIKAKDPDVPVIFISARDADIDRVLGLELGSNDYISKPFLPRELIIRVQKLLQLV
HHHHHHHHCCCCCCCEEEEECCCCCCHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
YKEAPPVQKNEIAVSSYRVAEDAREVYDENGNIINLTSKEFDLLLLFIHHKGHPYSREDI
HHCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEECCCCCCCCCCE
LLKVWGHDYFGTDRVVDDLVRRLRRKMPELKVETIYGFGYRMMSS
EEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEECCC
>Mature Secondary Structure 
SYTIYLVEDEDNLNELLTKYLENEGWNITSFTKGEDARKKMTPSPHLWILDIMLPDTDG
CEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCCCEEEEEEEECCCCC
YTLIKEIKAKDPDVPVIFISARDADIDRVLGLELGSNDYISKPFLPRELIIRVQKLLQLV
HHHHHHHHCCCCCCCEEEEECCCCCCHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
YKEAPPVQKNEIAVSSYRVAEDAREVYDENGNIINLTSKEFDLLLLFIHHKGHPYSREDI
HHCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEECCCCCCCCCCE
LLKVWGHDYFGTDRVVDDLVRRLRRKMPELKVETIYGFGYRMMSS
EEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9639930; 9384377; 11555295