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The map label for this gene is mrpG

Identifier: 16080217

GI number: 16080217

Start: 3251992

End: 3252366

Strand: Direct

Name: mrpG

Synonym: BSU31660

Alternate gene names: 16080217

Gene position: 3251992-3252366 (Clockwise)

Preceding gene: 255767722

Following gene: 255767726

Centisome position: 77.14

GC content: 44.8

Gene sequence:

>375_bases
ATGATCGAAACCGCTAAGGTCGTTGTGGCTGTATTCATTTTGCTGGGTGCTCTTATATGCCTCATTGCTTCATTTGGCGT
ACTTCGCCTTCCCGATGTGTTTACACGCGCTCATGCTGCTTCTAAAGGCTCAACATTAGGTGTCAATATGATTCTGCTCG
GTGTCTTCTTCTATTTGTGGTTTGTGACGGGGGAGCTCTCCGCTAAAATCCTGCTTGGGATTCTCTTTATCTTTATTACG
TCGCCTATCGGCGGGCACTTGATCTGCCGTGCTGCGTATAACTCCGGCGTCAAGCTTGATGAGAGAAGTGTGCAAGATGA
CTATAACGGAATCAGAAACTTTGTGATTAAACGAAAAGAGGATTCTTATTTATAA

Upstream 100 bases:

>100_bases
ACAAGTGCGTTTTTGGATATTATTTTGTTGCTGGGGATTTTATCGTTTATCGGAACGATCGCATTTTCCAAGTTCCTGGA
GAAAGGAGAGATTATCGAAA

Downstream 100 bases:

>100_bases
AAATAAGCAGCCGGACAGGCAGAGTTCCGGCTGTTTTTTTATTTCTTGATGACAGCCAGCGTGCATCTGGATATACAGAT
CAGCCTCTCTTGCTCGTCAT

Product: monovalent cation/H+ antiporter subunit G

Products: NA

Alternate protein names: Mrp complex subunit G; Multiple resistance and pH homeostasis protein G

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MIETAKVVVAVFILLGALICLIASFGVLRLPDVFTRAHAASKGSTLGVNMILLGVFFYLWFVTGELSAKILLGILFIFIT
SPIGGHLICRAAYNSGVKLDERSVQDDYNGIRNFVIKRKEDSYL

Sequences:

>Translated_124_residues
MIETAKVVVAVFILLGALICLIASFGVLRLPDVFTRAHAASKGSTLGVNMILLGVFFYLWFVTGELSAKILLGILFIFIT
SPIGGHLICRAAYNSGVKLDERSVQDDYNGIRNFVIKRKEDSYL
>Mature_124_residues
MIETAKVVVAVFILLGALICLIASFGVLRLPDVFTRAHAASKGSTLGVNMILLGVFFYLWFVTGELSAKILLGILFIFIT
SPIGGHLICRAAYNSGVKLDERSVQDDYNGIRNFVIKRKEDSYL

Specific function: Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual N

COG id: COG1320

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhG subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRPG_BACSU (O05227)

Other databases:

- EMBL:   Z93932
- EMBL:   AL009126
- PIR:   E70008
- RefSeq:   NP_391044.1
- EnsemblBacteria:   EBBACT00000000588
- GeneID:   938864
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU31660
- NMPDR:   fig|224308.1.peg.3169
- GenoList:   BSU31660
- GeneTree:   EBGT00050000002508
- HOGENOM:   HBG754276
- OMA:   RMHSASK
- ProtClustDB:   PRK12674
- BioCyc:   BSUB:BSU31660-MONOMER
- InterPro:   IPR005133
- TIGRFAMs:   TIGR01300

Pfam domain/function: PF03334 PhaG_MnhG_YufB

EC number: NA

Molecular weight: Translated: 13626; Mature: 13626

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11cbc9d4)-; HASH(0x11ba74cc)-; HASH(0x120fb860)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETAKVVVAVFILLGALICLIASFGVLRLPDVFTRAHAASKGSTLGVNMILLGVFFYLW
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
FVTGELSAKILLGILFIFITSPIGGHLICRAAYNSGVKLDERSVQDDYNGIRNFVIKRKE
HHHCCHHHHHHHHHHHHHHHCCCCCHHEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
DSYL
CCCH
>Mature Secondary Structure
MIETAKVVVAVFILLGALICLIASFGVLRLPDVFTRAHAASKGSTLGVNMILLGVFFYLW
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
FVTGELSAKILLGILFIFITSPIGGHLICRAAYNSGVKLDERSVQDDYNGIRNFVIKRKE
HHHCCHHHHHHHHHHHHHHHCCCCCHHEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
DSYL
CCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 10198001; 11356194