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The map label for this gene is ktrB

Identifier: 16080162

GI number: 16080162

Start: 3189089

End: 3190426

Strand: Direct

Name: ktrB

Synonym: BSU31100

Alternate gene names: 16080162

Gene position: 3189089-3190426 (Clockwise)

Preceding gene: 16080161

Following gene: 16080166

Centisome position: 75.65

GC content: 43.2

Gene sequence:

>1338_bases
GTGACACTTCAAAAGGATAAAGTGATCAAATGGGTTCGGTTTACACCGCCTCAAGTGCTTGCCATTGGTTTTTTCCTTAC
CATTATCATCGGGGCTGTCCTATTAATGCTTCCGATTTCCACTACGAAGCCATTGTCATGGATAGATGCCCTTTTTACTG
CGGCTTCCGCTACAACTGTTACAGGGCTTGCTGTTGTCGATACCGGCACTCAATTTACGGTATTCGGGCAAACAGTAATT
ATGGGGCTGATTCAGATTGGCGGGCTTGGATTTATGACATTTGCGGTCTTGATCGTCATGATATTAGGAAAAAAAATCGG
CTTAAAAGAACGAATGCTCGTCCAGGAAGCCTTAAACCAGCCGACAATCGGCGGTGTCATTGGCCTTGTCAAAGTCCTGT
TTCTGTTTTCGATCAGTATTGAATTGATAGCAGCACTCATTTTATCCATCCGGCTTGTACCTCAATACGGCTGGTCATCC
GGCTTGTTTGCAAGTTTGTTTCACGCAATATCTGCTTTTAACAATGCCGGGTTTTCGTTGTGGCCTGATAATTTGATGAG
CTACGTTGGCGATCCTACAGTGAACCTCGTGATTACTTTCTTATTTATTACAGGAGGGATCGGATTTACGGTTCTGTTTG
ATGTGATGAAAAATCGGCGTTTTAAAACTTTTTCTTTACATACAAAGCTCATGCTTACAGGAACGCTGATGTTGAATGCG
ATCGCTATGCTTACGGTCTTTATTTTAGAATACAGCAACCCCGGCACGCTCGGCCACCTGCATATAGTGGATAAACTGTG
GGCCTCCTATTTTCAGGCAGTGACGCCGAGAACCGCAGGGTTCAATTCTCTAGATTTTGGAAGCATGAGAGAAGGAACAA
TTGTATTTACTTTATTATTGATGTTTATCGGAGCAGGAAGCGCATCAACGGCGAGCGGCATTAAGCTGACTACGTTCATC
GTGATTTTAACATCTGTTATTGCTTACTTGAGAGGTAAAAAAGAAACGGTTATTTTCCGCCGTTCCATCAAATATCCGAT
TATCATTAAAGCTTTAGCTGTGAGCGTCACCAGTTTGTTCATCGTGTTTTTAGGGATTTTCGCCCTGACGATCACAGAAC
AAGCGCCATTTCTTCAAATTGTGTTTGAAACCTTTTCCGCATTCGGAACTGTCGGCCTTACGATGGGGCTTACTCCTGAA
CTGACAACAGCTGGCAAGTGTATCATCATTGTCATCATGTTTATCGGAAGAATTGGTCCTTTAACGTTCGTGTTTTCATT
CGCAAAAACAGAGCAATCAAATATCCGTTATCCTGATGGCGAAGTGTTTACAGGGTGA

Upstream 100 bases:

>100_bases
CCCCGCGCCTGAAGACATCATTCGCGAGCAAGATTGCCTGGTGATCATGGGCCACAAAAAGGATATTAAACGTTTTGAAA
ACGAAGGGATGTAGACAAAG

Downstream 100 bases:

>100_bases
TATCAAAAAAATCCGGCGTGCAGTCGCCGGATTTTTTATGATTCGATATGAGATTGATTTTGTCTTTTTTCCTGTTCCGC
GATGATTTCGTTATCCTCCG

Product: potassium transporter ATPase

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: K(+)-uptake protein ktrB

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MTLQKDKVIKWVRFTPPQVLAIGFFLTIIIGAVLLMLPISTTKPLSWIDALFTAASATTVTGLAVVDTGTQFTVFGQTVI
MGLIQIGGLGFMTFAVLIVMILGKKIGLKERMLVQEALNQPTIGGVIGLVKVLFLFSISIELIAALILSIRLVPQYGWSS
GLFASLFHAISAFNNAGFSLWPDNLMSYVGDPTVNLVITFLFITGGIGFTVLFDVMKNRRFKTFSLHTKLMLTGTLMLNA
IAMLTVFILEYSNPGTLGHLHIVDKLWASYFQAVTPRTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFI
VILTSVIAYLRGKKETVIFRRSIKYPIIIKALAVSVTSLFIVFLGIFALTITEQAPFLQIVFETFSAFGTVGLTMGLTPE
LTTAGKCIIIVIMFIGRIGPLTFVFSFAKTEQSNIRYPDGEVFTG

Sequences:

>Translated_445_residues
MTLQKDKVIKWVRFTPPQVLAIGFFLTIIIGAVLLMLPISTTKPLSWIDALFTAASATTVTGLAVVDTGTQFTVFGQTVI
MGLIQIGGLGFMTFAVLIVMILGKKIGLKERMLVQEALNQPTIGGVIGLVKVLFLFSISIELIAALILSIRLVPQYGWSS
GLFASLFHAISAFNNAGFSLWPDNLMSYVGDPTVNLVITFLFITGGIGFTVLFDVMKNRRFKTFSLHTKLMLTGTLMLNA
IAMLTVFILEYSNPGTLGHLHIVDKLWASYFQAVTPRTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFI
VILTSVIAYLRGKKETVIFRRSIKYPIIIKALAVSVTSLFIVFLGIFALTITEQAPFLQIVFETFSAFGTVGLTMGLTPE
LTTAGKCIIIVIMFIGRIGPLTFVFSFAKTEQSNIRYPDGEVFTG
>Mature_444_residues
TLQKDKVIKWVRFTPPQVLAIGFFLTIIIGAVLLMLPISTTKPLSWIDALFTAASATTVTGLAVVDTGTQFTVFGQTVIM
GLIQIGGLGFMTFAVLIVMILGKKIGLKERMLVQEALNQPTIGGVIGLVKVLFLFSISIELIAALILSIRLVPQYGWSSG
LFASLFHAISAFNNAGFSLWPDNLMSYVGDPTVNLVITFLFITGGIGFTVLFDVMKNRRFKTFSLHTKLMLTGTLMLNAI
AMLTVFILEYSNPGTLGHLHIVDKLWASYFQAVTPRTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFIV
ILTSVIAYLRGKKETVIFRRSIKYPIIIKALAVSVTSLFIVFLGIFALTITEQAPFLQIVFETFSAFGTVGLTMGLTPEL
TTAGKCIIIVIMFIGRIGPLTFVFSFAKTEQSNIRYPDGEVFTG

Specific function: Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family. Ktr (TC 2.A.38.4) subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KTRB_BACSU (O32081)

Other databases:

- EMBL:   AL009126
- PIR:   B70007
- RefSeq:   NP_390988.1
- ProteinModelPortal:   O32081
- EnsemblBacteria:   EBBACT00000003352
- GeneID:   938835
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU31100
- NMPDR:   fig|224308.1.peg.3113
- GenoList:   BSU31100
- GeneTree:   EBGT00050000000977
- HOGENOM:   HBG565935
- OMA:   YWSTFGQ
- ProtClustDB:   CLSK2748872
- BioCyc:   BSUB:BSU31100-MONOMER
- InterPro:   IPR003445
- InterPro:   IPR004772
- TIGRFAMs:   TIGR00933

Pfam domain/function: PF02386 TrkH

EC number: NA

Molecular weight: Translated: 48438; Mature: 48307

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x116c36ec)-; HASH(0x11c65798)-; HASH(0x11df76d8)-; HASH(0x11f431b4)-; HASH(0x11eae5b0)-; HASH(0x119934b4)-; HASH(0x118fe9e8)-; HASH(0x1202b738)-; HASH(0x11bdc818)-; HASH(0x10f3fb34)-; HASH(0x11ae1ce8)-; HASH(0x10dc4944)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCCCCCCCCCCH
>Mature Secondary Structure 
TLQKDKVIKWVRFTPPQVLAIGFFLTIIIGAVLLMLPISTTKPLSWIDALFTAASATTV
CCCHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TGLAVVDTGTQFTVFGQTVIMGLIQIGGLGFMTFAVLIVMILGKKIGLKERMLVQEALNQ
EEEEEEECCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
PTIGGVIGLVKVLFLFSISIELIAALILSIRLVPQYGWSSGLFASLFHAISAFNNAGFSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC
WPDNLMSYVGDPTVNLVITFLFITGGIGFTVLFDVMKNRRFKTFSLHTKLMLTGTLMLNA
CHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
IAMLTVFILEYSNPGTLGHLHIVDKLWASYFQAVTPRTAGFNSLDFGSMREGTIVFTLLL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
MFIGAGSASTASGIKLTTFIVILTSVIAYLRGKKETVIFRRSIKYPIIIKALAVSVTSLF
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
IVFLGIFALTITEQAPFLQIVFETFSAFGTVGLTMGLTPELTTAGKCIIIVIMFIGRIGP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHCCCH
LTFVFSFAKTEQSNIRYPDGEVFTG
HHHHHHHHHCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377