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The map label for this gene is ktrA

Identifier: 16080161

GI number: 16080161

Start: 3188414

End: 3189082

Strand: Direct

Name: ktrA

Synonym: BSU31090

Alternate gene names: 16080161

Gene position: 3188414-3189082 (Clockwise)

Preceding gene: 16080160

Following gene: 16080162

Centisome position: 75.63

GC content: 42.3

Gene sequence:

>669_bases
TTGGGAAGAATTAAAAATAAGCAATTTGCCGTGATCGGGCTGGGCCGGTTTGGCGGCAGCATTTGTAAAGAACTTCATAG
AATGGGGCATGAGGTCCTTGCGGTTGATATCAACGAAGAAAAGGTCAATGCATATGCTTCTTACGCCACTCATGCGGTAA
TTGCCAACGCCACCGAAGAAAACGAATTGCTTTCATTAGGAATACGCAATTTTGAATATGTGATTGTTGCCATCGGAGCA
AATATTCAAGCGAGTACGCTGACCACCCTATTATTAAAGGAGCTTGATATTCCAAATATTTGGGTGAAGGCTCAAAACTA
TTATCATCACAAGGTGCTTGAAAAAATAGGCGCTGACCGCATTATTCATCCTGAAAAAGATATGGGGGTTAAAATCGCAC
AAAGCCTTTCAGACGAAAATGTTTTGAATTACATTGATCTATCTGATGAATACAGTATTGTCGAGCTGCTGGCTACGCGC
AAGCTTGATTCAAAATCGATTATTGACCTGAATGTAAGAGCAAAGTACGGCTGCACGATCCTGGCCATTAAACATCATGG
AGATATCTGTCTTTCCCCCGCGCCTGAAGACATCATTCGCGAGCAAGATTGCCTGGTGATCATGGGCCACAAAAAGGATA
TTAAACGTTTTGAAAACGAAGGGATGTAG

Upstream 100 bases:

>100_bases
ACCTCGTAGGCGTATACAGAGAGGAGGTCTATTATCGGCCATTCTTTGCAATGGTCTTTTTTGTTTCAAAAACGTTAATT
CACTAAGGGAGATATGAACA

Downstream 100 bases:

>100_bases
ACAAAGGTGACACTTCAAAAGGATAAAGTGATCAAATGGGTTCGGTTTACACCGCCTCAAGTGCTTGCCATTGGTTTTTT
CCTTACCATTATCATCGGGG

Product: potassium uptake protein

Products: NA

Alternate protein names: K(+)-uptake protein ktrA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MGRIKNKQFAVIGLGRFGGSICKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATEENELLSLGIRNFEYVIVAIGA
NIQASTLTTLLLKELDIPNIWVKAQNYYHHKVLEKIGADRIIHPEKDMGVKIAQSLSDENVLNYIDLSDEYSIVELLATR
KLDSKSIIDLNVRAKYGCTILAIKHHGDICLSPAPEDIIREQDCLVIMGHKKDIKRFENEGM

Sequences:

>Translated_222_residues
MGRIKNKQFAVIGLGRFGGSICKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATEENELLSLGIRNFEYVIVAIGA
NIQASTLTTLLLKELDIPNIWVKAQNYYHHKVLEKIGADRIIHPEKDMGVKIAQSLSDENVLNYIDLSDEYSIVELLATR
KLDSKSIIDLNVRAKYGCTILAIKHHGDICLSPAPEDIIREQDCLVIMGHKKDIKRFENEGM
>Mature_221_residues
GRIKNKQFAVIGLGRFGGSICKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATEENELLSLGIRNFEYVIVAIGAN
IQASTLTTLLLKELDIPNIWVKAQNYYHHKVLEKIGADRIIHPEKDMGVKIAQSLSDENVLNYIDLSDEYSIVELLATRK
LDSKSIIDLNVRAKYGCTILAIKHHGDICLSPAPEDIIREQDCLVIMGHKKDIKRFENEGM

Specific function: Catalytic subunit of the ktrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and ktrCD confer resistance to both suddenly imposed and prolonged osmotic stress

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KTRA_BACSU (O32080)

Other databases:

- EMBL:   AL009126
- PIR:   C70005
- RefSeq:   NP_390987.1
- PDB:   1LSU
- PDB:   2HMS
- PDB:   2HMT
- PDB:   2HMU
- PDB:   2HMV
- PDB:   2HMW
- PDBsum:   1LSU
- PDBsum:   2HMS
- PDBsum:   2HMT
- PDBsum:   2HMU
- PDBsum:   2HMV
- PDBsum:   2HMW
- ProteinModelPortal:   O32080
- SMR:   O32080
- EnsemblBacteria:   EBBACT00000001102
- GeneID:   937145
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU31090
- NMPDR:   fig|224308.1.peg.3112
- GenoList:   BSU31090
- GeneTree:   EBGT00050000000827
- HOGENOM:   HBG320753
- OMA:   YVVEIHI
- ProtClustDB:   CLSK872713
- BioCyc:   BSUB:BSU31090-MONOMER
- GO:   GO:0005488
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148
- Gene3D:   G3DSA:3.40.50.720

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N

EC number: NA

Molecular weight: Translated: 24882; Mature: 24751

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS51202 RCK_C; PS51201 RCK_N

Important sites: BINDING 16-16 BINDING 109-109 BINDING 125-125

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRIKNKQFAVIGLGRFGGSICKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATEE
CCCCCCCEEEEEEEHHCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHEEEECCCCC
NELLSLGIRNFEYVIVAIGANIQASTLTTLLLKELDIPNIWVKAQNYYHHKVLEKIGADR
CCEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCC
IIHPEKDMGVKIAQSLSDENVLNYIDLSDEYSIVELLATRKLDSKSIIDLNVRAKYGCTI
CCCCCCCCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEEEEECCEEE
LAIKHHGDICLSPAPEDIIREQDCLVIMGHKKDIKRFENEGM
EEEEECCCEEECCCCHHHHCCCCCEEEECCHHHHHHHHCCCC
>Mature Secondary Structure 
GRIKNKQFAVIGLGRFGGSICKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATEE
CCCCCCEEEEEEEHHCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHEEEECCCCC
NELLSLGIRNFEYVIVAIGANIQASTLTTLLLKELDIPNIWVKAQNYYHHKVLEKIGADR
CCEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCC
IIHPEKDMGVKIAQSLSDENVLNYIDLSDEYSIVELLATRKLDSKSIIDLNVRAKYGCTI
CCCCCCCCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEEEEECCEEE
LAIKHHGDICLSPAPEDIIREQDCLVIMGHKKDIKRFENEGM
EEEEECCCEEECCCCHHHHCCCCCEEEECCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 12086676