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The map label for this gene is yplQ

Identifier: 16079238

GI number: 16079238

Start: 2295302

End: 2295943

Strand: Direct

Name: yplQ

Synonym: BSU21790

Alternate gene names: 16079238

Gene position: 2295302-2295943 (Clockwise)

Preceding gene: 16079237

Following gene: 255767480

Centisome position: 54.45

GC content: 44.08

Gene sequence:

>642_bases
TTGTTTACAATCAAAGAAGAGATCGCCAATGCGATTACACACGGCATCGGTGTCCTCTTATCCATCCCAGCATTAGTGTT
TCTAATCATATTTGCGGCTAATTACGGGTCTGCATGGGACATTGTCAGCTTTACAATATTCGGTGTCTCTATGCTGCTGT
TATATTTGAGCTCCACCCTGCTTCACAGCATCACACATAAAAAAACGAAGGACATTTTGGAGATTATTGATCATAGCGCA
ATTTACGTACTCATCGCCGGAACCTACACGCCTTTTTTGCTTGGGCCGCTGAAAGGCACACTCGGCTTTACCCTGTTGGT
TATCGTATGGTCACTTGCCCTAGGCGGAATCGTTTTTAAAATTTTCTTTGTGAAACGGTTTATCCTATTGTCAACCTTCG
TGTATTTAGTCATGGGGTGGCTGATGATTATTGCAGTTAAACCTTTATATGCTTCACTGAGCGGAGCGGGATTCAGCCTC
CTTTTTCTCGGCGGCATTTTATACTCTGTCGGAACCATCTTTTACATTTGGAAAAAGATCCCCTTCCATCACGCCATTTG
GCACAGCTTTGTATTGGGCGGGAGCGCTGCCATGTTTTTCTGCGTGCTCTTCTATTGTGTAAAGGTGCCTTTCCTTTCGT
AA

Upstream 100 bases:

>100_bases
AAAGCCGCGGACGCGCAGGCACAAAAATTACCTTTGAGGGCTTGAGCTTTATAGAGACGTTAAAAAATCAAATGATCTAG
CGATCGAAAGGAGAATGTAC

Downstream 100 bases:

>100_bases
CAGTAACAGAAAAGCGCAGTCTTCACGACTGCGCTTTTTTATGCACGTAATTGTTTTTCATTGGCAGGTATATAAGCTTT
TGAAAAGGACAATTCAATGT

Product: membrane hydrolase

Products: NA

Alternate protein names: Hemolysin III homolog

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MFTIKEEIANAITHGIGVLLSIPALVFLIIFAANYGSAWDIVSFTIFGVSMLLLYLSSTLLHSITHKKTKDILEIIDHSA
IYVLIAGTYTPFLLGPLKGTLGFTLLVIVWSLALGGIVFKIFFVKRFILLSTFVYLVMGWLMIIAVKPLYASLSGAGFSL
LFLGGILYSVGTIFYIWKKIPFHHAIWHSFVLGGSAAMFFCVLFYCVKVPFLS

Sequences:

>Translated_213_residues
MFTIKEEIANAITHGIGVLLSIPALVFLIIFAANYGSAWDIVSFTIFGVSMLLLYLSSTLLHSITHKKTKDILEIIDHSA
IYVLIAGTYTPFLLGPLKGTLGFTLLVIVWSLALGGIVFKIFFVKRFILLSTFVYLVMGWLMIIAVKPLYASLSGAGFSL
LFLGGILYSVGTIFYIWKKIPFHHAIWHSFVLGGSAAMFFCVLFYCVKVPFLS
>Mature_213_residues
MFTIKEEIANAITHGIGVLLSIPALVFLIIFAANYGSAWDIVSFTIFGVSMLLLYLSSTLLHSITHKKTKDILEIIDHSA
IYVLIAGTYTPFLLGPLKGTLGFTLLVIVWSLALGGIVFKIFFVKRFILLSTFVYLVMGWLMIIAVKPLYASLSGAGFSL
LFLGGILYSVGTIFYIWKKIPFHHAIWHSFVLGGSAAMFFCVLFYCVKVPFLS

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family

Homologues:

Organism=Homo sapiens, GI52630445, Length=218, Percent_Identity=27.9816513761468, Blast_Score=87, Evalue=8e-18,
Organism=Homo sapiens, GI154759275, Length=215, Percent_Identity=30.2325581395349, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI154759277, Length=239, Percent_Identity=27.1966527196653, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1789266, Length=205, Percent_Identity=47.3170731707317, Blast_Score=190, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI71996356, Length=209, Percent_Identity=31.5789473684211, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640324, Length=222, Percent_Identity=29.2792792792793, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HLY3_BACSU (P54175)

Other databases:

- EMBL:   L77246
- EMBL:   AL009126
- PIR:   D69938
- RefSeq:   NP_390062.1
- ProteinModelPortal:   P54175
- EnsemblBacteria:   EBBACT00000003604
- GeneID:   939095
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU21790
- NMPDR:   fig|224308.1.peg.2185
- GenoList:   BSU21790
- GeneTree:   EBGT00050000001179
- HOGENOM:   HBG717325
- OMA:   IDHSSIY
- PhylomeDB:   P54175
- ProtClustDB:   CLSK887467
- BioCyc:   BSUB:BSU21790-MONOMER
- GO:   GO:0019835
- InterPro:   IPR004254
- InterPro:   IPR005744
- PANTHER:   PTHR20855
- PANTHER:   PTHR20855:SF3
- TIGRFAMs:   TIGR01065

Pfam domain/function: PF03006 HlyIII

EC number: NA

Molecular weight: Translated: 23589; Mature: 23589

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x104e4410)-; HASH(0x10208518)-; HASH(0x1055feb8)-; HASH(0x10546248)-; HASH(0x1055b5cc)-; HASH(0xfe3c438)-; HASH(0x10250054)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTIKEEIANAITHGIGVLLSIPALVFLIIFAANYGSAWDIVSFTIFGVSMLLLYLSSTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LHSITHKKTKDILEIIDHSAIYVLIAGTYTPFLLGPLKGTLGFTLLVIVWSLALGGIVFK
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFVKRFILLSTFVYLVMGWLMIIAVKPLYASLSGAGFSLLFLGGILYSVGTIFYIWKKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
PFHHAIWHSFVLGGSAAMFFCVLFYCVKVPFLS
CHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MFTIKEEIANAITHGIGVLLSIPALVFLIIFAANYGSAWDIVSFTIFGVSMLLLYLSSTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LHSITHKKTKDILEIIDHSAIYVLIAGTYTPFLLGPLKGTLGFTLLVIVWSLALGGIVFK
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFVKRFILLSTFVYLVMGWLMIIAVKPLYASLSGAGFSLLFLGGILYSVGTIFYIWKKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
PFHHAIWHSFVLGGSAAMFFCVLFYCVKVPFLS
CHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377