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The map label for this gene is y4tK

Identifier: 16519957

GI number: 16519957

Start: 181114

End: 182109

Strand: Reverse

Name: y4tK

Synonym: NGR_a01480

Alternate gene names: NA

Gene position: 182109-181114 (Counterclockwise)

Preceding gene: 16519956

Following gene: 16519958

Centisome position: 33.97

GC content: 57.13

Gene sequence:

>996_bases
ATGCCTACAATGAAAATACTCACTGAGGGGGAGTTGAGGCAAATCGTGCCGCTCGACCTCGACGCGGTTAAGTGCACCGA
AGACGCTTTCCGCGCACTCGCCGTACCAAACGCCGTAAAAATGCCGCCCATTCTGCGCTTGGACGTGCCTGACAGCAGGG
GTGAAGTCGATGTGAAAACTGCGTATATTCCCGGTTTGGGCGGTTTTGCGATTAAGATCAGCCCCGGCTTCTTCGACAAC
CCAAAGATCGGCCTTCCGAGCACAAATGGGATGATGGTATTGCTCTCGAGCCAAACGGGTTTGGTTCAAGCGCTTCTTTT
AGACAATGGTTACCTCACCGACGTTCGTACGGCGGCCGCTGGCGCCGTTGCTGCAAAACATTTGTCGCAACAAGATGCTT
CGGTCGCAACCATCTTTGGAGCGGGCGTTCAGGCGAGACTGCAACTGCGTGCGCTGACTCTGGTGAGGCCTATCCGCCAA
GCCCGTATATGGGCGCGCGATCAGCTTAAGGCGGAGGCACTCGTCGAGCAGTTGAAGCTTGAGCATAGCTTCGCCATCAG
CGCGTCCGATGATCCACGGCAAGCCGTTTCCGGTGCCCATATCGTTGTTACGACGACGCCCGCAGACCGGCCAATCCTCG
TAGCGTCCTGGCTTGAAGCTGGGCAGCATGTAACTGCAATGGGCTCCGACGCTGAGCATAAAAACGAACTTGATCCAGCG
GCAATCGCGCGCGCGGATGTTTATGTGGCGGATAGTCTTACACAGACACGGAGACTGGGTGAACTTCACCATGCCATAGA
GGCAGGCCTCATCGCGCGGGACGCTGCTTTTCCGGAGTTGGGGGAGGTGATTGCGGGCGTGAAAACCGGACGTACCCGCG
AGTCAGATATCACTATAGCAGATCTTACGGGGACCGGTGTCCAGGACACGGCAATTGCCACGCTTGCCTTTCAGCGCGCC
GAAGAACGCAGTGCCGGAAGCCTATTCGAGAGCTGA

Upstream 100 bases:

>100_bases
GCGGAGGTTCAGTAGGAGTCGTTTTGTCAGGTCAAAACATCGACATGGGCCTGCATCGGGAGGTCATTAACGGAGTTGTC
AGAGCGACCGAGGAGGATTG

Downstream 100 bases:

>100_bases
ACAACTCGCGCTCCTGACGCCTCAGCCATGTTGAGGCGCTGACTTCTCATCTGTTCACACGTTACCTTAGTATCCGCCGT
CCTGCGGACAATCATGCAAC

Product: ectoine utilization protein EutC

Products: L-proline; NH3

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MPTMKILTEGELRQIVPLDLDAVKCTEDAFRALAVPNAVKMPPILRLDVPDSRGEVDVKTAYIPGLGGFAIKISPGFFDN
PKIGLPSTNGMMVLLSSQTGLVQALLLDNGYLTDVRTAAAGAVAAKHLSQQDASVATIFGAGVQARLQLRALTLVRPIRQ
ARIWARDQLKAEALVEQLKLEHSFAISASDDPRQAVSGAHIVVTTTPADRPILVASWLEAGQHVTAMGSDAEHKNELDPA
AIARADVYVADSLTQTRRLGELHHAIEAGLIARDAAFPELGEVIAGVKTGRTRESDITIADLTGTGVQDTAIATLAFQRA
EERSAGSLFES

Sequences:

>Translated_331_residues
MPTMKILTEGELRQIVPLDLDAVKCTEDAFRALAVPNAVKMPPILRLDVPDSRGEVDVKTAYIPGLGGFAIKISPGFFDN
PKIGLPSTNGMMVLLSSQTGLVQALLLDNGYLTDVRTAAAGAVAAKHLSQQDASVATIFGAGVQARLQLRALTLVRPIRQ
ARIWARDQLKAEALVEQLKLEHSFAISASDDPRQAVSGAHIVVTTTPADRPILVASWLEAGQHVTAMGSDAEHKNELDPA
AIARADVYVADSLTQTRRLGELHHAIEAGLIARDAAFPELGEVIAGVKTGRTRESDITIADLTGTGVQDTAIATLAFQRA
EERSAGSLFES
>Mature_330_residues
PTMKILTEGELRQIVPLDLDAVKCTEDAFRALAVPNAVKMPPILRLDVPDSRGEVDVKTAYIPGLGGFAIKISPGFFDNP
KIGLPSTNGMMVLLSSQTGLVQALLLDNGYLTDVRTAAAGAVAAKHLSQQDASVATIFGAGVQARLQLRALTLVRPIRQA
RIWARDQLKAEALVEQLKLEHSFAISASDDPRQAVSGAHIVVTTTPADRPILVASWLEAGQHVTAMGSDAEHKNELDPAA
IARADVYVADSLTQTRRLGELHHAIEAGLIARDAAFPELGEVIAGVKTGRTRESDITIADLTGTGVQDTAIATLAFQRAE
ERSAGSLFES

Specific function: Unknown

COG id: COG2423

COG function: function code E; Predicted ornithine cyclodeaminase, mu-crystallin homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ornithine cyclodeaminase family

Homologues:

Organism=Homo sapiens, GI4503065, Length=286, Percent_Identity=29.7202797202797, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI62241008, Length=281, Percent_Identity=29.8932384341637, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24642678, Length=297, Percent_Identity=26.2626262626263, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y4TK_RHISN (P55665)

Other databases:

- EMBL:   U00090
- RefSeq:   NP_444077.1
- ProteinModelPortal:   P55665
- SMR:   P55665
- GeneID:   962225
- GenomeReviews:   U00090_GR
- KEGG:   rhi:NGR_a01480
- HOGENOM:   HBG300196
- ProtClustDB:   PRK08291
- GO:   GO:0005488
- InterPro:   IPR014334
- InterPro:   IPR016040
- InterPro:   IPR003462
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR13812
- TIGRFAMs:   TIGR02992

Pfam domain/function: PF02423 OCD_Mu_crystall

EC number: 4.3.1.12

Molecular weight: Translated: 35208; Mature: 35076

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTMKILTEGELRQIVPLDLDAVKCTEDAFRALAVPNAVKMPPILRLDVPDSRGEVDVKT
CCCCEEEECCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEE
AYIPGLGGFAIKISPGFFDNPKIGLPSTNGMMVLLSSQTGLVQALLLDNGYLTDVRTAAA
EEECCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEHHHHHHH
GAVAAKHLSQQDASVATIFGAGVQARLQLRALTLVRPIRQARIWARDQLKAEALVEQLKL
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHSFAISASDDPRQAVSGAHIVVTTTPADRPILVASWLEAGQHVTAMGSDAEHKNELDPA
HHEEEEECCCCHHHHHCCCEEEEEECCCCCCEEEEEHHHCCCEEEECCCCCCCCCCCCHH
AIARADVYVADSLTQTRRLGELHHAIEAGLIARDAAFPELGEVIAGVKTGRTRESDITIA
HHHHEEEEEEHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEE
DLTGTGVQDTAIATLAFQRAEERSAGSLFES
EECCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PTMKILTEGELRQIVPLDLDAVKCTEDAFRALAVPNAVKMPPILRLDVPDSRGEVDVKT
CCCEEEECCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEE
AYIPGLGGFAIKISPGFFDNPKIGLPSTNGMMVLLSSQTGLVQALLLDNGYLTDVRTAAA
EEECCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEHHHHHHH
GAVAAKHLSQQDASVATIFGAGVQARLQLRALTLVRPIRQARIWARDQLKAEALVEQLKL
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHSFAISASDDPRQAVSGAHIVVTTTPADRPILVASWLEAGQHVTAMGSDAEHKNELDPA
HHEEEEECCCCHHHHHCCCEEEEEECCCCCCEEEEEHHHCCCEEEECCCCCCCCCCCCHH
AIARADVYVADSLTQTRRLGELHHAIEAGLIARDAAFPELGEVIAGVKTGRTRESDITIA
HHHHEEEEEEHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEE
DLTGTGVQDTAIATLAFQRAEERSAGSLFES
EECCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-ornithine

Specific reaction: L-ornithine = L-proline + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424