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The map label for this gene is noeK

Identifier: 16519648

GI number: 16519648

Start: 46885

End: 48309

Strand: Direct

Name: noeK

Synonym: NGR_a00390

Alternate gene names: 16519648

Gene position: 46885-48309 (Clockwise)

Preceding gene: 16519656

Following gene: 16519647

Centisome position: 8.74

GC content: 58.81

Gene sequence:

>1425_bases
ATGGGTCCCAAATTCGGCACAAGTGGTCTGCGCGGGTTGGCAACAGAACTCGTGGGTAGTGTGTCGGCGCTCTATGCTAC
AGCCTTTTCGAGGATGCTCCTCGACAGAGGACGGGTCGCGCCAGGGGCGACCGTATTGGTCGGTCGCGACTTCCGCGATT
CAAGTTCGGAAATCGCCGCTATCTGCATGGCGGCGCTCGCCCGGGCGGGAATGGTGCCGGTCGACTGCGGAGGGCTGCCG
ACACCAGCGCTTGCATTGTACGGCCGAAAACTCGGTGCAGCATCACTCATGATCACAGGCTCGCATATTCCGGCCGACCG
AAACGGCATTAAGTTCTATCTGCCTGACGGTGAGATCAACAAGGCCGACGAGCAGGCGATTACGGCGTTGGCGGAGCAGC
TTTCAGCCGATGCAGATGCAACCAGGGTTGAGTGTGGCCGCGGCGCCGACCACTCCAGCGAAGCAACTGACTTCTATATC
CAACGTTACGAAACGCTGCTTCCAAAATCGGGCCTTAAGGGGCTAAAGATCGGCTTATATCAGCACAGCAGCGTTGCCCG
CGATATTTTGACCACCATCTTGGAAGGTCATGGCGCAAATGTCGTACCGGTAGGCCGATCTGAGGTCTTCATCCCTGTTG
ACACGGAAGCTATTTCGGCGGCGACATGTAAGATGCTCGCTGCCTGGGCGAAGGAGTTCGCCTTTGACGCCATTGTATCG
TCCGACGCAGATGCCGATCGGCCCCTGCTAACGGATGAAACGGGAACTCCATTGCGCGGTGATCTGCTCGGTCTTATTTG
CGCAAGGCTGCTGGAGGCCAAGCTTATTGCTACGCCAATAACCAGCAACTCCGGGATCGAGGCGGCGAGTGGCGTCGAGG
TGGTGCGTACCCGCGTTGGCTCACCTTACGTCATTGCAGCCATGACTGAGGCGGTTGCCCGTGGCAAGCAGCGGGTGATG
GGCTTCGAGGCCAACGGTGGCGTCATGCTAGGTTCGAACTTCTCGTTCGGAGGCGCGTCGCTTCCCGCCTTGCCGACCCG
GGACTGCGTCCTTCCCATCATTGCAGCGCTCCACATGGCAGTAGAGGCCAAAACTCCCCTCTCGGGGATCGTCGCGATGC
ATCGTTTGCCAGTCGCTTTGTCCGGCCGGATCGAGAACTATCCGTTCGATAGGAGCGACGCCCTAGTGGCATTCTTGAAA
GCGTCAAAAGCTAATGTTTCCCATTTATTCAGCCGGATCGGTCGCGTGGCGGGCACGGACGACGTGGATGGCCTGCGCCT
GACATTTGAAGGCGGCCGTATCCTGCACATCCGCCCTTCAGGAAATGCGCCTGAACTGCGTTGCTACGTCGAGGCAGACG
ACCCAGATGCTGCCGAACATTTGCTGGCTCAGGGACTGGCGGTCCTTAACAGTTCAATGGTGTAA

Upstream 100 bases:

>100_bases
CGAGAGCGAAGCAATCTCATTAGTGGATGCGAATTCATTCGGCTTGCCCCGGTGGCGTCGACTACCTGCTGAACGCTGCC
CGGCAAAAAAAGGCTAGTTA

Downstream 100 bases:

>100_bases
GTTAGGCTTTGCTGATATGCAGATCTGTTACCGCTAGCGTCGATGGTTCGCCACCTAACGTGAAGATAAGCCCTGAAAGA
CACGTCCCCTTTACATCCAA

Product: phosphomanomutase

Products: NA

Alternate protein names: PMM

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MGPKFGTSGLRGLATELVGSVSALYATAFSRMLLDRGRVAPGATVLVGRDFRDSSSEIAAICMAALARAGMVPVDCGGLP
TPALALYGRKLGAASLMITGSHIPADRNGIKFYLPDGEINKADEQAITALAEQLSADADATRVECGRGADHSSEATDFYI
QRYETLLPKSGLKGLKIGLYQHSSVARDILTTILEGHGANVVPVGRSEVFIPVDTEAISAATCKMLAAWAKEFAFDAIVS
SDADADRPLLTDETGTPLRGDLLGLICARLLEAKLIATPITSNSGIEAASGVEVVRTRVGSPYVIAAMTEAVARGKQRVM
GFEANGGVMLGSNFSFGGASLPALPTRDCVLPIIAALHMAVEAKTPLSGIVAMHRLPVALSGRIENYPFDRSDALVAFLK
ASKANVSHLFSRIGRVAGTDDVDGLRLTFEGGRILHIRPSGNAPELRCYVEADDPDAAEHLLAQGLAVLNSSMV

Sequences:

>Translated_474_residues
MGPKFGTSGLRGLATELVGSVSALYATAFSRMLLDRGRVAPGATVLVGRDFRDSSSEIAAICMAALARAGMVPVDCGGLP
TPALALYGRKLGAASLMITGSHIPADRNGIKFYLPDGEINKADEQAITALAEQLSADADATRVECGRGADHSSEATDFYI
QRYETLLPKSGLKGLKIGLYQHSSVARDILTTILEGHGANVVPVGRSEVFIPVDTEAISAATCKMLAAWAKEFAFDAIVS
SDADADRPLLTDETGTPLRGDLLGLICARLLEAKLIATPITSNSGIEAASGVEVVRTRVGSPYVIAAMTEAVARGKQRVM
GFEANGGVMLGSNFSFGGASLPALPTRDCVLPIIAALHMAVEAKTPLSGIVAMHRLPVALSGRIENYPFDRSDALVAFLK
ASKANVSHLFSRIGRVAGTDDVDGLRLTFEGGRILHIRPSGNAPELRCYVEADDPDAAEHLLAQGLAVLNSSMV
>Mature_473_residues
GPKFGTSGLRGLATELVGSVSALYATAFSRMLLDRGRVAPGATVLVGRDFRDSSSEIAAICMAALARAGMVPVDCGGLPT
PALALYGRKLGAASLMITGSHIPADRNGIKFYLPDGEINKADEQAITALAEQLSADADATRVECGRGADHSSEATDFYIQ
RYETLLPKSGLKGLKIGLYQHSSVARDILTTILEGHGANVVPVGRSEVFIPVDTEAISAATCKMLAAWAKEFAFDAIVSS
DADADRPLLTDETGTPLRGDLLGLICARLLEAKLIATPITSNSGIEAASGVEVVRTRVGSPYVIAAMTEAVARGKQRVMG
FEANGGVMLGSNFSFGGASLPALPTRDCVLPIIAALHMAVEAKTPLSGIVAMHRLPVALSGRIENYPFDRSDALVAFLKA
SKANVSHLFSRIGRVAGTDDVDGLRLTFEGGRILHIRPSGNAPELRCYVEADDPDAAEHLLAQGLAVLNSSMV

Specific function: Unknown

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=464, Percent_Identity=27.5862068965517, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NOEK_RHISN (P55356)

Other databases:

- EMBL:   U00090
- RefSeq:   NP_443768.1
- ProteinModelPortal:   P55356
- GeneID:   962306
- GenomeReviews:   U00090_GR
- KEGG:   rhi:NGR_a00390
- HOGENOM:   HBG644964
- ProtClustDB:   CLSK784548
- GO:   GO:0009877
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- Gene3D:   G3DSA:3.40.120.10

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.8

Molecular weight: Translated: 49672; Mature: 49540

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 101-101

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPKFGTSGLRGLATELVGSVSALYATAFSRMLLDRGRVAPGATVLVGRDFRDSSSEIAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHH
ICMAALARAGMVPVDCGGLPTPALALYGRKLGAASLMITGSHIPADRNGIKFYLPDGEIN
HHHHHHHHCCCCEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCC
KADEQAITALAEQLSADADATRVECGRGADHSSEATDFYIQRYETLLPKSGLKGLKIGLY
CHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEE
QHSSVARDILTTILEGHGANVVPVGRSEVFIPVDTEAISAATCKMLAAWAKEFAFDAIVS
CCHHHHHHHHHHHHCCCCCCEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHC
SDADADRPLLTDETGTPLRGDLLGLICARLLEAKLIATPITSNSGIEAASGVEVVRTRVG
CCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHCC
SPYVIAAMTEAVARGKQRVMGFEANGGVMLGSNFSFGGASLPALPTRDCVLPIIAALHMA
CCEEHHHHHHHHHCCHHHEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VEAKTPLSGIVAMHRLPVALSGRIENYPFDRSDALVAFLKASKANVSHLFSRIGRVAGTD
HHCCCCHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
DVDGLRLTFEGGRILHIRPSGNAPELRCYVEADDPDAAEHLLAQGLAVLNSSMV
CCCCEEEEECCCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GPKFGTSGLRGLATELVGSVSALYATAFSRMLLDRGRVAPGATVLVGRDFRDSSSEIAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHH
ICMAALARAGMVPVDCGGLPTPALALYGRKLGAASLMITGSHIPADRNGIKFYLPDGEIN
HHHHHHHHCCCCEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCC
KADEQAITALAEQLSADADATRVECGRGADHSSEATDFYIQRYETLLPKSGLKGLKIGLY
CHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEE
QHSSVARDILTTILEGHGANVVPVGRSEVFIPVDTEAISAATCKMLAAWAKEFAFDAIVS
CCHHHHHHHHHHHHCCCCCCEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHC
SDADADRPLLTDETGTPLRGDLLGLICARLLEAKLIATPITSNSGIEAASGVEVVRTRVG
CCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHCC
SPYVIAAMTEAVARGKQRVMGFEANGGVMLGSNFSFGGASLPALPTRDCVLPIIAALHMA
CCEEHHHHHHHHHCCHHHEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VEAKTPLSGIVAMHRLPVALSGRIENYPFDRSDALVAFLKASKANVSHLFSRIGRVAGTD
HHCCCCHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
DVDGLRLTFEGGRILHIRPSGNAPELRCYVEADDPDAAEHLLAQGLAVLNSSMV
CCCCEEEEECCCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424