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The map label for this gene is tktB [C]

Identifier: 15668862

GI number: 15668862

Start: 607002

End: 607826

Strand: Reverse

Name: tktB [C]

Synonym: MJ0681

Alternate gene names: 15668862

Gene position: 607826-607002 (Counterclockwise)

Preceding gene: 15668863

Following gene: 15668861

Centisome position: 36.51

GC content: 34.91

Gene sequence:

>825_bases
ATGGATAATAACTTAGAAATAAAAGATTTGGAAAAAATAGCAAAAAAGGTTAGATATAATATTGTAAAAATGGTTGGTTT
AGCAAAGTCTGGACATCCAGGTGGAAGTTTATCAGCAACTGATATTATAGTAGCTCTATACTTTAAACTAATGAACTACT
CTCCAGATAATCCATATAAAAAAGATAGAGATAGGTTTGTTTTAAGTAAAGGACATGCTGCTCCAGCATTATATGCAGTT
TTGTCTGAGTTGGGTATAATAGAAGAGGAGGAGTTATGGAAATTGAGAAGATTGGAAGGGAAGTTGCAAGGACACCCATC
AATGGATACACCAGGAGTTGAGATTTGCACCGGTTCATTGGGACAAGGTTTTTCAGCAGCAGTAGGAATGGCTTTGGGAT
GTAGATTAGATAAGTTAAACAACTACGTTTATGTCTTATTAGGGGATGGAGAATGTCAAGAGGGTATAGTTTGGGAAGCT
GCAATGGCAGCAGCCCACTACAAGTTGGATAACTTAATTGCCTTTATTGATAGAAATAAACTGCAGATAGATGGATGTAC
TGAGGATGTTATGAGTTTAGGAGATATAAAAGCTAAATTTGAGGCATTTGGATGGGATGTCTTTGAAATAGATGGACATA
ACTTTGAAGAGATTATAAATACTGTAGAAAAAGCCAAAAGCATGAAAAATGGCAAACCAAAGATGATTATTGCATATACC
GTTAAAGGTAAGGGAGTTTCATTCATGGAGAATAATGTTGCATTCCATGGAAAGGCTCCAAATGAAGAACAATTAAAACA
AGCATTAGAAGAATTAAGTGAATAA

Upstream 100 bases:

>100_bases
ATTATTTTAGCATAACATCATTATGGATTTTTTGTTTTTGCTTTTTTTATTAATTCATTGAGTAATGATATTATTTTTTA
AATCTTAAAAAGGTGAAACT

Downstream 100 bases:

>100_bases
AATTTTATTTTTTGGTGATTTAAATGATTAAAATTGGAGCTTCAATACTATCTGCTGATTTTGGGCATTTAAGGGAGGAG
ATTAAAAAGGCAGAGGAAGC

Product: transketolase'

Products: NA

Alternate protein names: TK

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MDNNLEIKDLEKIAKKVRYNIVKMVGLAKSGHPGGSLSATDIIVALYFKLMNYSPDNPYKKDRDRFVLSKGHAAPALYAV
LSELGIIEEEELWKLRRLEGKLQGHPSMDTPGVEICTGSLGQGFSAAVGMALGCRLDKLNNYVYVLLGDGECQEGIVWEA
AMAAAHYKLDNLIAFIDRNKLQIDGCTEDVMSLGDIKAKFEAFGWDVFEIDGHNFEEIINTVEKAKSMKNGKPKMIIAYT
VKGKGVSFMENNVAFHGKAPNEEQLKQALEELSE

Sequences:

>Translated_274_residues
MDNNLEIKDLEKIAKKVRYNIVKMVGLAKSGHPGGSLSATDIIVALYFKLMNYSPDNPYKKDRDRFVLSKGHAAPALYAV
LSELGIIEEEELWKLRRLEGKLQGHPSMDTPGVEICTGSLGQGFSAAVGMALGCRLDKLNNYVYVLLGDGECQEGIVWEA
AMAAAHYKLDNLIAFIDRNKLQIDGCTEDVMSLGDIKAKFEAFGWDVFEIDGHNFEEIINTVEKAKSMKNGKPKMIIAYT
VKGKGVSFMENNVAFHGKAPNEEQLKQALEELSE
>Mature_274_residues
MDNNLEIKDLEKIAKKVRYNIVKMVGLAKSGHPGGSLSATDIIVALYFKLMNYSPDNPYKKDRDRFVLSKGHAAPALYAV
LSELGIIEEEELWKLRRLEGKLQGHPSMDTPGVEICTGSLGQGFSAAVGMALGCRLDKLNNYVYVLLGDGECQEGIVWEA
AMAAAHYKLDNLIAFIDRNKLQIDGCTEDVMSLGDIKAKFEAFGWDVFEIDGHNFEEIINTVEKAKSMKNGKPKMIIAYT
VKGKGVSFMENNVAFHGKAPNEEQLKQALEELSE

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family

Homologues:

Organism=Homo sapiens, GI205277463, Length=268, Percent_Identity=40.6716417910448, Blast_Score=202, Evalue=3e-52,
Organism=Homo sapiens, GI4507521, Length=268, Percent_Identity=40.6716417910448, Blast_Score=202, Evalue=3e-52,
Organism=Homo sapiens, GI133778974, Length=269, Percent_Identity=39.4052044609665, Blast_Score=194, Evalue=7e-50,
Organism=Homo sapiens, GI225637459, Length=266, Percent_Identity=30.8270676691729, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI225637461, Length=235, Percent_Identity=31.4893617021277, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI225637463, Length=230, Percent_Identity=31.7391304347826, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI1788808, Length=273, Percent_Identity=37.3626373626374, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI48994911, Length=275, Percent_Identity=36.3636363636364, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1786304, Length=285, Percent_Identity=25.9649122807018, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17539652, Length=251, Percent_Identity=44.6215139442231, Blast_Score=216, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6325331, Length=279, Percent_Identity=39.7849462365591, Blast_Score=161, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6319593, Length=276, Percent_Identity=36.231884057971, Blast_Score=155, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24666278, Length=267, Percent_Identity=38.5767790262172, Blast_Score=185, Evalue=3e-47,
Organism=Drosophila melanogaster, GI45551847, Length=253, Percent_Identity=38.7351778656126, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI45550715, Length=253, Percent_Identity=38.7351778656126, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24645119, Length=214, Percent_Identity=40.1869158878505, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TKTN_METJA (Q58094)

Other databases:

- EMBL:   L77117
- PIR:   A64385
- RefSeq:   NP_247665.1
- ProteinModelPortal:   Q58094
- SMR:   Q58094
- GeneID:   1451547
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0681
- NMPDR:   fig|243232.1.peg.702
- TIGR:   MJ0681
- HOGENOM:   HBG670382
- OMA:   WYSVLAR
- ProtClustDB:   CLSK876292
- BioCyc:   MJAN243232:MJ_0681-MONOMER
- BRENDA:   2.2.1.1
- InterPro:   IPR005474

Pfam domain/function: PF00456 Transketolase_N

EC number: =2.2.1.1

Molecular weight: Translated: 30336; Mature: 30336

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNNLEIKDLEKIAKKVRYNIVKMVGLAKSGHPGGSLSATDIIVALYFKLMNYSPDNPYK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
KDRDRFVLSKGHAAPALYAVLSELGIIEEEELWKLRRLEGKLQGHPSMDTPGVEICTGSL
CCCCCEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
GQGFSAAVGMALGCRLDKLNNYVYVLLGDGECQEGIVWEAAMAAAHYKLDNLIAFIDRNK
CCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCE
LQIDGCTEDVMSLGDIKAKFEAFGWDVFEIDGHNFEEIINTVEKAKSMKNGKPKMIIAYT
EEECCCHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
VKGKGVSFMENNVAFHGKAPNEEQLKQALEELSE
ECCCCCEEEECCEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDNNLEIKDLEKIAKKVRYNIVKMVGLAKSGHPGGSLSATDIIVALYFKLMNYSPDNPYK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
KDRDRFVLSKGHAAPALYAVLSELGIIEEEELWKLRRLEGKLQGHPSMDTPGVEICTGSL
CCCCCEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
GQGFSAAVGMALGCRLDKLNNYVYVLLGDGECQEGIVWEAAMAAAHYKLDNLIAFIDRNK
CCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCE
LQIDGCTEDVMSLGDIKAKFEAFGWDVFEIDGHNFEEIINTVEKAKSMKNGKPKMIIAYT
EEECCCHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
VKGKGVSFMENNVAFHGKAPNEEQLKQALEELSE
ECCCCCEEEECCEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087