Click here to switch to the map view.

The map label for this gene is citT [C]

Identifier: 15668853

GI number: 15668853

Start: 597692

End: 598990

Strand: Reverse

Name: citT [C]

Synonym: MJ0672

Alternate gene names: 15668853

Gene position: 598990-597692 (Counterclockwise)

Preceding gene: 15668856

Following gene: 15668852

Centisome position: 35.98

GC content: 29.87

Gene sequence:

>1299_bases
ATGAGATTATCCAAAGAATTTATAGGCTTAGGGATAATTACAGCTTCTCTTATTTTTGGCTCATCTTTACCAGATATATA
CAAAGGTATTGTTATATTAATAGTTGCTGGATGTTTATGGTTTTTTGAATTATTGCCTCTTCCAGTTACATCCTTAGCAA
TACCAATAATGGCAGTGTTTTTAGGAATTTTTAATTTAAAAGAGGCTTTAACATACTTTGCCCATCCAATAATATTTTTG
TTTTTGGGAGGATTTATGCTTGCACAGGCATTAAAAAATCATAACTTAGATAAATTTATTGCCTATAAGCTACTAAATTA
TGGAAAGGATTTTAAAACTACATGTTTTTTAATGTTTCTATCGGCTTATTTTCTATCAATGTGGATTAGTAACACCTCTG
CCACATTAATTTTGTTGCCCATAGCTCTTGGTCTATTACATAAAAAAACTGGTAAATTGAGAGATTTTTTATTGTTAGGA
GTTGCTTATTCTGCCTCTATAGGAGGAATAGCAACAATTATCGGCTCTCCACCAAATGCCATAGCAAGTAGCTATCTAGA
TTATGGATTTTTTAGCTGGTTTAAAGTGGGATTTCCAATAAGTTTATTGTTATTTTTGATTTGTACTTTAACATTATATA
TTTACTTTAAAAAGTGGATTCCAAAAGAAGATATTGCTATTCAAGCAAGAATGGAGTTGAGTAGAAACGCTTATAAATTA
TTGGTCATATTTGTGTTAATAGCTTCACTTTGGATAATTAGCGACTATTTGAGTGAAATTTTTAATGTCCAATATTTTGA
TTCAGTTATTGCCATATTCGCCATAATTTTATTGTTTGTATTTAATTTAGTTGAAGTTAATGATTTTAAGAAAATAGATT
GGGGAACTTTAATTTTATTTGGTGGAGCTTTATGTTTGGGAGGAGTTATTGTTAAGAGTGGAGCAAATACATTCTTATCT
GAAAAACTTATAGCTATCTTAGGAAATTTAACTCCAATTGTTCTTTTATTTTTAGTAGTTACAATAACAATAATTCTAAC
TAATTTTATAAGCAACACTGGATTGACTGGAATAATAGTCCCAATACTATTTGGAGTATCTTTAGGAATTCCAAAAGAGA
TTTTAATACTGGCTGTTGGTATGTCAGCATCGTGCTCTTTTATTCTGCCAGTAGGGACTCCTCCCAACGCTATTGTATAT
AGTGAAGGTGTCAAAAAAGAAGAAATGATGAAAATTGGGATGATTTTATCAATACTATCTGCAGCTGTAATAACTCTATA
TTCCATTCTTTATCTATAA

Upstream 100 bases:

>100_bases
GAGTCTATGAATAATGAATAAACATACAAGAGATATAAAAACTTAACTATTAACATACCTAAGTTATAAAGTAAAGAAAT
AAATCTGGTGGGGGAGGGAT

Downstream 100 bases:

>100_bases
AATTTAGCTATCATTTAGAATATAAAACTTAAATTTTATTAACTAAACATTTAAAATTGGTGATGGTAATGGAAAAAAAG
CCATACATTATCTCAAATGT

Product: membrane bound transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MRLSKEFIGLGIITASLIFGSSLPDIYKGIVILIVAGCLWFFELLPLPVTSLAIPIMAVFLGIFNLKEALTYFAHPIIFL
FLGGFMLAQALKNHNLDKFIAYKLLNYGKDFKTTCFLMFLSAYFLSMWISNTSATLILLPIALGLLHKKTGKLRDFLLLG
VAYSASIGGIATIIGSPPNAIASSYLDYGFFSWFKVGFPISLLLFLICTLTLYIYFKKWIPKEDIAIQARMELSRNAYKL
LVIFVLIASLWIISDYLSEIFNVQYFDSVIAIFAIILLFVFNLVEVNDFKKIDWGTLILFGGALCLGGVIVKSGANTFLS
EKLIAILGNLTPIVLLFLVVTITIILTNFISNTGLTGIIVPILFGVSLGIPKEILILAVGMSASCSFILPVGTPPNAIVY
SEGVKKEEMMKIGMILSILSAAVITLYSILYL

Sequences:

>Translated_432_residues
MRLSKEFIGLGIITASLIFGSSLPDIYKGIVILIVAGCLWFFELLPLPVTSLAIPIMAVFLGIFNLKEALTYFAHPIIFL
FLGGFMLAQALKNHNLDKFIAYKLLNYGKDFKTTCFLMFLSAYFLSMWISNTSATLILLPIALGLLHKKTGKLRDFLLLG
VAYSASIGGIATIIGSPPNAIASSYLDYGFFSWFKVGFPISLLLFLICTLTLYIYFKKWIPKEDIAIQARMELSRNAYKL
LVIFVLIASLWIISDYLSEIFNVQYFDSVIAIFAIILLFVFNLVEVNDFKKIDWGTLILFGGALCLGGVIVKSGANTFLS
EKLIAILGNLTPIVLLFLVVTITIILTNFISNTGLTGIIVPILFGVSLGIPKEILILAVGMSASCSFILPVGTPPNAIVY
SEGVKKEEMMKIGMILSILSAAVITLYSILYL
>Mature_432_residues
MRLSKEFIGLGIITASLIFGSSLPDIYKGIVILIVAGCLWFFELLPLPVTSLAIPIMAVFLGIFNLKEALTYFAHPIIFL
FLGGFMLAQALKNHNLDKFIAYKLLNYGKDFKTTCFLMFLSAYFLSMWISNTSATLILLPIALGLLHKKTGKLRDFLLLG
VAYSASIGGIATIIGSPPNAIASSYLDYGFFSWFKVGFPISLLLFLICTLTLYIYFKKWIPKEDIAIQARMELSRNAYKL
LVIFVLIASLWIISDYLSEIFNVQYFDSVIAIFAIILLFVFNLVEVNDFKKIDWGTLILFGGALCLGGVIVKSGANTFLS
EKLIAILGNLTPIVLLFLVVTITIILTNFISNTGLTGIIVPILFGVSLGIPKEILILAVGMSASCSFILPVGTPPNAIVY
SEGVKKEEMMKIGMILSILSAAVITLYSILYL

Specific function: Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates. [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family

Homologues:

Organism=Homo sapiens, GI29171306, Length=496, Percent_Identity=25.8064516129032, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI4506979, Length=526, Percent_Identity=26.615969581749, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI301069346, Length=490, Percent_Identity=23.265306122449, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI225637549, Length=469, Percent_Identity=26.6524520255864, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI225637552, Length=469, Percent_Identity=26.6524520255864, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI31795546, Length=327, Percent_Identity=28.1345565749235, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI31377715, Length=351, Percent_Identity=25.0712250712251, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI58761541, Length=351, Percent_Identity=25.0712250712251, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI301069353, Length=351, Percent_Identity=25.0712250712251, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI301069349, Length=331, Percent_Identity=24.4712990936556, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI19923838, Length=341, Percent_Identity=28.4457478005865, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71989118, Length=504, Percent_Identity=26.3888888888889, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71988385, Length=495, Percent_Identity=27.2727272727273, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI32565804, Length=457, Percent_Identity=27.3522975929978, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17551790, Length=510, Percent_Identity=24.5098039215686, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32564681, Length=482, Percent_Identity=25.103734439834, Blast_Score=95, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6324340, Length=403, Percent_Identity=27.2952853598015, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322263, Length=402, Percent_Identity=26.1194029850746, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319885, Length=419, Percent_Identity=26.9689737470167, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI45551633, Length=472, Percent_Identity=25.4237288135593, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281366409, Length=472, Percent_Identity=25.4237288135593, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17737623, Length=472, Percent_Identity=25.4237288135593, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24666468, Length=472, Percent_Identity=25.4237288135593, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y672_METJA (Q58086)

Other databases:

- EMBL:   L77117
- PIR:   H64383
- RefSeq:   NP_247656.1
- ProteinModelPortal:   Q58086
- GeneID:   1451538
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0672
- NMPDR:   fig|243232.1.peg.693
- TIGR:   MJ0672
- HOGENOM:   HBG616159
- OMA:   MLTLAWL
- ProtClustDB:   CLSK2517643
- BioCyc:   MJAN243232:MJ_0672-MONOMER
- InterPro:   IPR001898
- TIGRFAMs:   TIGR00785

Pfam domain/function: PF00939 Na_sulph_symp

EC number: NA

Molecular weight: Translated: 47542; Mature: 47542

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS01271 NA_SULFATE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcff5088)-; HASH(0xd4773c8)-; HASH(0xd3e7694)-; HASH(0xc7f62dc)-; HASH(0xccb3200)-; HASH(0xca71468)-; HASH(0xbd69c48)-; HASH(0xd4ac804)-; HASH(0xcd9a32c)-; HASH(0xbf285c0)-; HASH(0xb2b6ec0)-; HASH(0xd1a4948)-; HASH(0xc5d9630)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHH
>Mature Secondary Structure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HHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087